The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
C. Crosti - One of the best experts on this subject based on the ideXlab platform.
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guess what subungual squamous cell carcinoma mimicking chronic Paronychia
European Journal of Dermatology, 2000Co-Authors: R Betti, Raffaella Vergani, Elena Inselvini, E Tolomio, C. CrostiAbstract:This clinical-pathological picture is consistent with subungual squamous cell carcinoma. A disarticulation of the little finger was then performed. Routine blood tests gave normal values, chest x-ray and medical examination were normal. The patient underwent a regular follow-up composed of medical examination every 6 months, chest X-ray and abdomen echography every year. During 2 years of follow-up signs of metastasis or recurrence have been [...]
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Unusual clinical features of fingernail infection by Fusarium oxysporum
1997Co-Authors: C. Gianni, A. Cerri, C. CrostiAbstract:Four cases of invasion of fingernails caused by Fusarium oxysporum are described. The typical picture of onychomycosis by this non-dermatophytic mould is a 'white superficial onychomycosis' which usually affects the great toenail. Only few cases of fingernail infections by this organism have been described in the literature and, to our knowledge, there are no reported cases on the pustulous and eczema-like aspect of Paronychia by Fusarium oxysporum. We report different and unusual clinical features of this infection successfully treated with systemic antifungals. Two patients were treated with terbinafine, 250 mg daily for 3 months, and two patients with itraconazole, 200 mg daily for 3 months
R Betti - One of the best experts on this subject based on the ideXlab platform.
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guess what subungual squamous cell carcinoma mimicking chronic Paronychia
European Journal of Dermatology, 2000Co-Authors: R Betti, Raffaella Vergani, Elena Inselvini, E Tolomio, C. CrostiAbstract:This clinical-pathological picture is consistent with subungual squamous cell carcinoma. A disarticulation of the little finger was then performed. Routine blood tests gave normal values, chest x-ray and medical examination were normal. The patient underwent a regular follow-up composed of medical examination every 6 months, chest X-ray and abdomen echography every year. During 2 years of follow-up signs of metastasis or recurrence have been [...]
Salomon M Stemmer - One of the best experts on this subject based on the ideXlab platform.
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staphylococcus coagulase positive skin inflammation associated with epidermal growth factor receptor targeted therapy an early and a late phase of papulopustular eruptions
Oncologist, 2010Co-Authors: Iris Amitaylaish, Michael David, Salomon M StemmerAbstract:Objective.Cutaneouseruptions,mainlypapulopustular, are the most common associated side effects of epidermal growth factor receptor inhibitors (EGFRIs). This study investigated the possible role of bacterial infection in EGFRI-induced eruptions and its relation to clinical morphology. PatientsandMethods.Thestudygroupconsistedofall 29 patients referred for dermatologic evaluation of side effects of cetuximab or erlotinib from March 2008 to November 2009. Specimens were taken for bacterial culture from pustules in patients with grade >1 papulopustular rash and from periungual secretions in patients with Paronychia. Results. Twenty-four of 29 patients had a papulopustular reaction; five of 29 had Paronychia/xerosis. Of the papulopustular eruption patients, time to rash appearance yielded two distinct groups: early-phase, median 8 days after drug initiation, located mainly on the face (n 17) and late-phase, median 200 days after drug
Mirella Dandrea - One of the best experts on this subject based on the ideXlab platform.
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are topical beta blockers really effective in real life for targeted therapy induced Paronychia
Supportive Care in Cancer, 2019Co-Authors: Vincent Sibaud, E Casassa, Mirella DandreaAbstract:Paronychia and periungual pyogenic granuloma represent one of the most common and bothersome dermatologic toxicities observed with ErbB inhibitors. There is no standardized treatment, and management remains challenging. Moreover, conservative management with noninvasive treatment should be promoted for fragile patients in a metastatic setting. Over the last few years, the efficacy of topical blocking agents has been considered for managing cutaneous or mucosal pyogenic granulomas. Very recently, the use of topical propranolol or of timolol has been reported in several patients undergoing treatment with EGFR inhibitors and developing pyogenic granulomas of the nail. We performed a retrospective single-center review of patients with targeted therapy-related Paronychia/periungual pyogenic granulomas who had been treated with topical timolol, either alone or in combination with other topical treatments. Nearly two thirds of patients showed at least a partial response after 1 month of therapy, and the use of a topical beta-blocker in our population was associated with a favorable safety profile. Finally, topical timolol may represent a promising treatment option for the management of cancer patients suffering from painful periungual lesions. Comparative clinical trials, however, are still needed.
Amir Feily - One of the best experts on this subject based on the ideXlab platform.
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images in clinical medicine squamous cell carcinoma of the nail bed
The New England Journal of Medicine, 2015Co-Authors: Amir FeilyAbstract:A healthy 61-year-old woman presented with a 3-year history of a nail deformity accompanied by an indolent ulcer on the left thumb. The lesion had been diagnosed as Paronychia and treated several times with incision and antibiotics. Mycologic results were negative.
