The Experts below are selected from a list of 16038 Experts worldwide ranked by ideXlab platform
Takahisa Hirose - One of the best experts on this subject based on the ideXlab platform.
-
Superior thyroid artery mean Peak Systolic Velocity for the diagnosis of thyrotoxicosis in Japanese patients.
Endocrine journal, 2010Co-Authors: Toyoyoshi Uchida, Kageumi Takeno, Masahiro Goto, Rei Kanno, Sayaka Kubo, Satomi Takahashi, K. Azuma, Ken Sakai, Yoshio Fujitani, Takahisa HiroseAbstract:Thyrotoxicosis with diffuse thyroid disease can be caused by Graves' disease (GD) or destructive thyroiditis (DT). Optimal treatment of the underlying condition requires a prompt and accurate method for the diagnosis of thyrotoxicosis. This study evaluated measurement of the mean Peak Systolic Velocity of the superior thyroid artery (STA-PSV) by ultrasonography in detecting thyrotoxicosis in Japanese patients. We recruited 44 patients with untreated GD, 13 with DT, 55 with treated GD, and 49 subjects without thyroid disease. Blood samples were taken to analyze thyroid function and STA-PSV was measured by ultrasonography. The mean STA-PSV was the highest in the untreated GD group, followed by treated GD patients and then those with DT. Receiver operating characteristic curves of the STA-PSV values demonstrated that the area under the curve required discriminating untreated GD from DT was 0.941. The optimal sensitivity and specificity were 83.7% and 92.3%, respectively, using 45 cm/sec as the cutoff value. In conclusion measurement of STA-PSV by ultrasonography is useful for the diagnosis of thyrotoxicosis in Japanese patients.
Maria Cristina Chammas - One of the best experts on this subject based on the ideXlab platform.
-
color duplex doppler us can follow up the response of radioiodine in graves disease by evaluating the thyroid volume and Peak Systolic Velocity
Ultraschall in Der Medizin, 2020Co-Authors: Thiago Adler Ralho Rodrigues Santos, Suemi Marui, Tomoco Watanabe, Nicolau Lima, Claudia Okanobo Ozaki, Giovanni Guido Cerri, Maria Cristina ChammasAbstract:Purpose The objective of this study was to prove the efficacy of Doppler ultrasonography (US-Doppler) in the follow-up of patients with GD treated with radioactive iodine. Methods 97 patients (77 female and 20 male) with a mean age of 42 years (SD ± 15) and with prior diagnosis of GD were treated with radioiodine. In total, 88.5 % achieved euthyroidism or hypothyroidism after treatment. The study was documented before treatment and one, three, and six months after treatment with radioactive iodine (131I) by a single investigator. The volume, echogenicity, echotexture and vascularization of the glands as well as the Peak Systolic Velocity (PSV) of the inferior thyroid arteries were evaluated and compared with the laboratory data. Results Thyroid volume and PSV had a statistically significant correlation with hormone levels (p Conclusion Doppler US was useful for monitoring the therapeutic response of GD patients after treatment with radioiodine by evaluating the thyroid volume and Peak Systolic Velocity.
-
Color Duplex Doppler US can Follow up the Response of Radioiodine in Graves' Disease by Evaluating the Thyroid Volume and Peak Systolic Velocity.
Ultraschall in der Medizin (Stuttgart Germany : 1980), 2019Co-Authors: Thiago Adler Ralho Rodrigues Santos, Suemi Marui, Tomoco Watanabe, Nicolau Lima, Claudia Okanobo Ozaki, Giovanni Guido Cerri, Maria Cristina ChammasAbstract:The objective of this study was to prove the efficacy of Doppler ultrasonography (US-Doppler) in the follow-up of patients with GD treated with radioactive iodine. 97 patients (77 female and 20 male) with a mean age of 42 years (SD ± 15) and with prior diagnosis of GD were treated with radioiodine. In total, 88.5 % achieved euthyroidism or hypothyroidism after treatment. The study was documented before treatment and one, three, and six months after treatment with radioactive iodine (131I) by a single investigator. The volume, echogenicity, echotexture and vascularization of the glands as well as the Peak Systolic Velocity (PSV) of the inferior thyroid arteries were evaluated and compared with the laboratory data. Thyroid volume and PSV had a statistically significant correlation with hormone levels (p < 0.05). The mean pre-dose therapeutic thyroid volume was 43.01 ± 3.88 cm3 and was 11.58 ± 11.26 cm3 6 months after treatment. The mean PSV before 131I was 90.06 ± 44.13 cm/s and decreased significantly over time (p < 0.001). Six months after the therapeutic dose, the mean PSV was 32.95 ± 16.36 cm/s. However, the subjective parameters did not have a significant correlation with the normalization of the thyroid hormones. Doppler US was useful for monitoring the therapeutic response of GD patients after treatment with radioiodine by evaluating the thyroid volume and Peak Systolic Velocity. Thieme. All rights reserved.
Kenneth J Moise - One of the best experts on this subject based on the ideXlab platform.
-
the effect of fetal heart rate on the Peak Systolic Velocity of the fetal middle cerebral artery
Obstetrics & Gynecology, 2009Co-Authors: Anthony Swartz, Michael S Ruma, Eunhee Kim, Amy H Herring, Kathryn M Menard, Kenneth J MoiseAbstract:OBJECTIVE To estimate the effect of an increase in the basal heart rate of the fetus on the middle cerebral artery Peak Systolic Velocity (MCA-PSV). METHODS This was a prospective longitudinal cohort. Patients between 14 and 36 weeks of gestation were enrolled (N=66). Ultrasound examinations were performed monthly. MCA-PSV measurements were assessed at 0-degree angle of insonation at basal fetal heart rate and after application of vibroacoustic stimulation. RESULTS A total of 514 MCA-PSV measurements were obtained in 66 fetuses. No difference in fetal heart rate before and after vibroacoustic stimulation was noted before 27 weeks of gestation. A significant increase in fetal heart rate after vibroacoustic stimulation was detected from a mean+/-standard deviation gestational age of 27.1+/-1.3 weeks onward. A significant decrease in the MCA-PSV was noted between before vibroacoustic stimulation and after vibroacoustic stimulation measurements for examinations 3,4, and 5 (P<.001 for all). CONCLUSION Acceleration of the fetal heart rate in the third trimester is associated with a decrease in the middle cerebral artery Peak Systolic Velocity. Assessment of the MCA-PSV for the detection of fetal anemia, particularly in the third trimester, should be undertaken during a period of baseline fetal heart rate to avoid the potential of a false-negative result. LEVEL OF EVIDENCE II.
-
Angle correction can be used to measure Peak Systolic Velocity in the fetal middle cerebral artery
American Journal of Obstetrics and Gynecology, 2009Co-Authors: Michael S Ruma, Eunhee Kim, Amy H Herring, Anthony E. Swartz, M. Kathryn Menard, Kenneth J MoiseAbstract:Objective The objective of the study was to compare Doppler ultrasound measurements of the fetal middle cerebral artery Peak Systolic Velocity (MCA-PSV) obtained at a 0° angle of insonation to assessment at 30° and 30° with angle correction. Study Design Patients between 14 and 36 weeks' gestation were enrolled (n = 66). MCA-PSV measurements were assessed at 0°, 30°, and 30° with angle correction. The data were analyzed using a mixed model adjusted for gestational age. Pairwise comparisons of mean MCA-PSV measurements were made using the Tukey multiple comparison test. Results All measurements were obtained for 50 fetuses (76%). Mean MCA-PSV measurements were statistically different between 0° vs 30° ( P = .03 to P = .34-.99) at each of the 5 gestational age groupings. Conclusion Assessment of the MCA-PSV at 0° and 30° with angle correction provides comparable measurements during the second and third trimester of pregnancy.
-
The effect of fetal heart rate on the Peak Systolic Velocity of the fetal middle cerebral artery.
Obstetrics and gynecology, 2009Co-Authors: Anthony E. Swartz, Michael S Ruma, Eunhee Kim, Amy H Herring, M. Kathryn Menard, Kenneth J MoiseAbstract:OBJECTIVE To estimate the effect of an increase in the basal heart rate of the fetus on the middle cerebral artery Peak Systolic Velocity (MCA-PSV). METHODS This was a prospective longitudinal cohort. Patients between 14 and 36 weeks of gestation were enrolled (N=66). Ultrasound examinations were performed monthly. MCA-PSV measurements were assessed at 0-degree angle of insonation at basal fetal heart rate and after application of vibroacoustic stimulation. RESULTS A total of 514 MCA-PSV measurements were obtained in 66 fetuses. No difference in fetal heart rate before and after vibroacoustic stimulation was noted before 27 weeks of gestation. A significant increase in fetal heart rate after vibroacoustic stimulation was detected from a mean+/-standard deviation gestational age of 27.1+/-1.3 weeks onward. A significant decrease in the MCA-PSV was noted between before vibroacoustic stimulation and after vibroacoustic stimulation measurements for examinations 3,4, and 5 (P
-
Determinants of the middle cerebral artery Peak Systolic Velocity in the human fetus.
American Journal of Obstetrics and Gynecology, 2007Co-Authors: Amy H. Picklesimer, Kenneth J Moise, Dick Oepkes, Michelle Kush, Carl P. Weiner, Christopher Harman, Ahmet BaschatAbstract:Objective The purpose of this study was to identify physiologic determinants of the Peak Systolic blood flow Velocity (PSV) of the middle cerebral artery (MCA) in the human fetus. Study Design MCA PSV was measured with pulsed wave Doppler ultrasound in human fetuses who underwent cordocentesis. Hemoglobin, hematocrit, and blood gas values were analyzed from umbilical venous blood, and the data were normalized for gestational age. Total oxygen content of fetal venous blood was calculated from oxygen saturation, hemoglobin value, and pO 2 . Correlation and logistic regression analyses were performed to identify primary physiologic determinants of MCA PSV. Results In 136 fetuses who underwent cordocentesis (predominantly for alloimmune disease), hematocrit, hemoglobin, and blood oxygen content correlated significantly with the MCA PSV ( P 2 , but not pO 2 or fetal blood oxygen content, accounted for increases in MCA PSV. Conclusion Under physiologic circumstances, fetal hemoglobin, and not fetal oxygenation, primarily determines the middle cerebral artery Peak Systolic Velocity.
-
Determinants of the middle cerebral artery Peak Systolic Velocity in the human fetus.
American journal of obstetrics and gynecology, 2007Co-Authors: Amy H. Picklesimer, Kenneth J Moise, Dick Oepkes, Michelle Kush, Carl P. Weiner, Christopher R Harman, Ahmet BaschatAbstract:The purpose of this study was to identify physiologic determinants of the Peak Systolic blood flow Velocity (PSV) of the middle cerebral artery (MCA) in the human fetus. MCA PSV was measured with pulsed wave Doppler ultrasound in human fetuses who underwent cordocentesis. Hemoglobin, hematocrit, and blood gas values were analyzed from umbilical venous blood, and the data were normalized for gestational age. Total oxygen content of fetal venous blood was calculated from oxygen saturation, hemoglobin value, and pO2. Correlation and logistic regression analyses were performed to identify primary physiologic determinants of MCA PSV. In 136 fetuses who underwent cordocentesis (predominantly for alloimmune disease), hematocrit, hemoglobin, and blood oxygen content correlated significantly with the MCA PSV (P < .01). Logistic regression modeling demonstrated that fetal hemoglobin content (odds ratio, 7.1; 95% CI, 3.71-13.7) and pCO2, but not pO2 or fetal blood oxygen content, accounted for increases in MCA PSV. Under physiologic circumstances, fetal hemoglobin, and not fetal oxygenation, primarily determines the middle cerebral artery Peak Systolic Velocity.
Toyoyoshi Uchida - One of the best experts on this subject based on the ideXlab platform.
-
Superior thyroid artery mean Peak Systolic Velocity for the diagnosis of thyrotoxicosis in Japanese patients.
Endocrine journal, 2010Co-Authors: Toyoyoshi Uchida, Kageumi Takeno, Masahiro Goto, Rei Kanno, Sayaka Kubo, Satomi Takahashi, K. Azuma, Ken Sakai, Yoshio Fujitani, Takahisa HiroseAbstract:Thyrotoxicosis with diffuse thyroid disease can be caused by Graves' disease (GD) or destructive thyroiditis (DT). Optimal treatment of the underlying condition requires a prompt and accurate method for the diagnosis of thyrotoxicosis. This study evaluated measurement of the mean Peak Systolic Velocity of the superior thyroid artery (STA-PSV) by ultrasonography in detecting thyrotoxicosis in Japanese patients. We recruited 44 patients with untreated GD, 13 with DT, 55 with treated GD, and 49 subjects without thyroid disease. Blood samples were taken to analyze thyroid function and STA-PSV was measured by ultrasonography. The mean STA-PSV was the highest in the untreated GD group, followed by treated GD patients and then those with DT. Receiver operating characteristic curves of the STA-PSV values demonstrated that the area under the curve required discriminating untreated GD from DT was 0.941. The optimal sensitivity and specificity were 83.7% and 92.3%, respectively, using 45 cm/sec as the cutoff value. In conclusion measurement of STA-PSV by ultrasonography is useful for the diagnosis of thyrotoxicosis in Japanese patients.
Timothy J Hurley - One of the best experts on this subject based on the ideXlab platform.
-
Discordant middle cerebral artery Peak Systolic Velocity Doppler studies in a fetus with RhD alloimmunization.
Obstetrics and gynecology, 2007Co-Authors: Eliza M F Berkley, Valerie J Rappaport, Timothy J HurleyAbstract:Doppler measurement of the fetal middle cerebral artery Peak Systolic Velocity is a valuable tool in detecting the presence of fetal anemia in Rh-sensitized pregnancies. We present a case in which discordant left and right middle cerebral artery Dopplers complicated clinical management. An RhD-alloimmunized patient had middle cerebral artery Dopplers at 30 weeks of gestation, which showed an elevated Peak Systolic Velocity in the left middle cerebral artery, greater than 1.55 multiples of the mean, but the right middle cerebral artery was within the normal range. The amniotic fluid change in optical density at a wavelength of 450 nm was consistent with the right middle cerebral artery Doppler. When both Dopplers were greater than or equal to 1.5 multiples of the mean, fetal blood sampling revealed a hematocrit of 28%. Postnatal cranial ultrasound examination showed normal architecture, but there was persistent discordant Dopplers in the left versus the right middle cerebral artery. Measurement of both left and right middle cerebral artery Peak Systolic velocities may identify patients with intrinsic variations in cranial blood vessels resulting in abnormal Doppler flows.
-
Discordant middle cerebral artery Peak Systolic Velocity Doppler studies in a fetus with RhD alloimmunization.
Obstetrics & Gynecology, 2007Co-Authors: Eliza M F Berkley, Valerie J Rappaport, Timothy J HurleyAbstract:BACKGROUND: Doppler measurement of the fetal middle cerebral artery Peak Systolic Velocity is a valuable tool in detecting the presence of fetal anemia in Rh-sensitized pregnancies. We present a case in which discordant left and right middle cerebral artery Dopplers complicated clinical management. CASE: An RhD-alloimmunized patient had middle cerebral artery Dopplers at 30 weeks of gestation, which showed an elevated Peak Systolic Velocity in the left middle cerebral artery, greater than 1.55 multiples of the mean, but the right middle cerebral artery was within the normal range. The amniotic fluid change in optical density at a wavelength of 450 nm was consistent with the right middle cerebral artery Doppler. When both Dopplers were greater than or equal to 1.5 multiples of the mean, fetal blood sampling revealed a hematocrit of 28%. Postnatal cranial ultrasound examination showed normal architecture, but there was persistent discordant Dopplers in the left versus the right middle cerebral artery. CONCLUSION: Measurement of both left and right middle cerebral artery Peak Systolic velocities may identify patients with intrinsic variations in cranial blood vessels resulting in abnormal Doppler flows.