The Experts below are selected from a list of 807 Experts worldwide ranked by ideXlab platform
Wu Hui-yin - One of the best experts on this subject based on the ideXlab platform.
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Telazosin hydrochloride combined with Qianlieanshuan treat chronic abacterial prostatitis/chronic Pelvis Pain Syndrome
Journal of Clinical and Experimental Medicine, 2008Co-Authors: Wu Hui-yinAbstract:Objective To investigate the efficacy and mechanism of telazosin hydrochloride combined with Qianlieanshuan to treat chronic abacterial prostatitis and chronic pelvic Pain Syndrome (CAP/CPPS).Methods Seventy eight patients diagnosed as CAP/CPPS were undergone a series of examinations including physical examination, urine analysis, seminal fluid conventional microscopic examination, bacteria cultivation of expressed prostatic secretions (EPS), medistream urine before prostatic massage and the beginning section urine after prostatic massage. The patients were randomly divided into experimental group and control group. After 6 weeks treatment, curative effect was compared between the two groups.Results Of the 40 cases in experimental group, 29 cases were cured, 7 cases improved, the total effective rate was 90.0%; of the 38 cases in control group, 16 cases were cured, 9 cases improved, the total effective rate was 65.8%. The difference between the two groups was significant (P0.01).Conclusion The combined use of telazosin hydrochloride and Qianlieanshuan for the treatment of CAP/CPPS may relax urethral smooth muscle and improve the urinary function, therefore relieve the symptoms of the chronic pelvic Pain and improve the effectiveness of the treatment. The combined treatment is safe.
W U Huiyin - One of the best experts on this subject based on the ideXlab platform.
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telazosin hydrochloride combined with qianlieanshuan treat chronic abacterial prostatitis chronic Pelvis Pain Syndrome
Journal of Clinical and Experimental Medicine, 2008Co-Authors: W U HuiyinAbstract:Objective To investigate the efficacy and mechanism of telazosin hydrochloride combined with Qianlieanshuan to treat chronic abacterial prostatitis and chronic pelvic Pain Syndrome (CAP/CPPS).Methods Seventy eight patients diagnosed as CAP/CPPS were undergone a series of examinations including physical examination, urine analysis, seminal fluid conventional microscopic examination, bacteria cultivation of expressed prostatic secretions (EPS), medistream urine before prostatic massage and the beginning section urine after prostatic massage. The patients were randomly divided into experimental group and control group. After 6 weeks treatment, curative effect was compared between the two groups.Results Of the 40 cases in experimental group, 29 cases were cured, 7 cases improved, the total effective rate was 90.0%; of the 38 cases in control group, 16 cases were cured, 9 cases improved, the total effective rate was 65.8%. The difference between the two groups was significant (P0.01).Conclusion The combined use of telazosin hydrochloride and Qianlieanshuan for the treatment of CAP/CPPS may relax urethral smooth muscle and improve the urinary function, therefore relieve the symptoms of the chronic pelvic Pain and improve the effectiveness of the treatment. The combined treatment is safe.
Anthony J. Schaeffer - One of the best experts on this subject based on the ideXlab platform.
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Prostatitis: US perspective.
International Journal of Antimicrobial Agents, 1998Co-Authors: Anthony J. SchaefferAbstract:The diagnosis and management of prostatitis Syndromes is a challenge to the clinician. Careful history and examination of the prostate fluid and quantitative segmented bacteriologic cultures will lead to proper categorization into the recognized forms of the prostatitis Syndrome. Antimicrobial therapy is effective in the majority of men with acute and chronic bacterial prostatitis (CBP). Fluoroquinolone agents appear to have an increasingly important role in this regard, although a randomized, prospective, double-blind study is still lacking. Alpha-1-selective blocking agents may relieve symptomatology of chronic Pelvis Pain Syndrome (CPPS). Other non-prostatic sources of voiding symptoms should be sought and ruled out, especially malignancy or inflammatory disorders.
Vladimira Kružić - One of the best experts on this subject based on the ideXlab platform.
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The role of Chlamydia trachomatis in the etiology of chronic prostatitis
European Urology, 2002Co-Authors: Ivan Krhen, Slavko Schönwald, Zvonimir Mareković, Višnja Škerk, Leo Markovinović, Vladimira KružićAbstract:INTRODUCTION & OBJECTIVES: Basic factors for the classification of prostatitis Syndrome are clinical symptoms and signs and the presence of bacteria and leukocytes in selectively collected urine samples and in EPS by Meares and Stamey localisation technique. The aim of this study was to investigate the etiology of chronic bacterial prostatitis and inflammatory chronic Pelvis Pain Syndrome i.e. nonbacterial prostatitis. MATERIALS & METHODS: We examined a total of 388 patients, older than 18 years of age, with symptoms of chronic prostatitis. The inclusion criteria for chronic bacterial prostatitis was as follows: - a bacterial count of 103 cfu/ml or more (if only Gram-positive cocci are found in EPS, a bacterial count of 10 x 104 cfu/ml or more is required), and 10 or more WBCs/hpf (including macrophages) in EPS or VB3 -finding of 10 or many times greater number of bacteria in EPS and urine bladder sample collected immediately after prostatic massage, than in first voided urine or midstream urine. The inclusion criteria for Chlamydia trachomatis prostatitis was the presence of 10 or more WBCs/hpf in EPS or VB3, the presence of Chlamydia trachomatis in EPS or VB3, absence of Chlamydia trachomatis in urethral swabs and other possible pathogens of chronic prostatitis in VB1, VB2, EPS or VB3. The inclusion criteria for nonbacterial prostatitis or inflammatory chronic Pelvis Pain Syndrome was the isolation of Ureaplasma urealyticum, Mycoplasma hominis or Trichomonas vaginalis and 10 or more WBCs/hpf in EPS of VB3. RESULTS: Disease etiology was determined in 276 (71, 13%) patients. Chlamydia trachomatis was proved to be causative in 109 patients, Trichomonas vaginalis in 52, Escherichia coli in 26, Enterococcus in 25, Proteus mirabilis in 14, Klebsiella pneumoniae in 6, Streptococcus agalactiae in 8, Ureaplasma urealyticum in 7patients with chronic prostatitis. Other patients with had mixed infection. CONCLUSION: Chlamydia trachomatis was proved to be the causative pathogen in one third of patients with chronic prostatitis. Since Chlamydia trachomatis is a bacterium, chlamydial prostatic infection should be defined as chronic bacterial prostatitis.
Jun-kyu Suh - One of the best experts on this subject based on the ideXlab platform.
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The Relationship between Inflammation or Bacterial Infection according to the Traditional 4-glass Tests or Tc-99m Ciprofloxacin Imaging and the Scores of the National Institute of Health-Chronic Prostatitis Symptom Index in Men with Chronic Prostatit
Korean Journal of Urology, 2006Co-Authors: Jae-seung Chung, Hwan Seong, Hun Jae Lee, Yeonsook Moon, Jun-kyu SuhAbstract:Purpose: We wanted to determine whether inflammation and bacterial infection, as tested for by the traditional 4-glass test or Tc-99m ciprofloxacin imaging, correlate with the symptom severity in men with chronic prostatitis. Materials and Methods: The study included 256 patients with symptoms of prostatitis. The Korean version of the National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI) was used to measure the symptoms of each patient. To diagnose bacterial infection, four-glass tests were performed that included culture for general bacteria, Mycoplasma hominis and Ureaplasma urealyticum, and polymerase chain reaction was performed for Chlamydia trachomatis. The patients with established uropathogens localized to the expressed prostatic secretion or the voided urine 3 were classified as having chronic bacterial prostatitis (CBP). To further localize the infection, the single photon emission computerized tomography images were obtained 3 hours after intravenous injection of Tc-99m ciprofloxacin. Associations between the symptoms and the inflammation and infection were evaluated. Results: Based on the 4-glass tests, the patients were classified as CBP (n=16) or as chronic Pelvis Pain Syndrome (CCPS) (the inflammatory type, n=94; non-inflammatory type, n=146). The CBP patients had a higher Pain score than did the CPPS patients and there were no significant differences in the subscores for voiding symptoms and the quality of life between the groups. No significant differences were found in the total score or the subscores of the NIH-CPSI based on the presence or location of infection on the Tc-99m ciprofloxacin imaging. Conclusions: These findings suggest that bacterial infection, not inflammation, as determined by traditional laboratory tests contribute to the symptoms, especially Pain, in men with chronic prostatitis. (Korean J Urol 2006; 47:870-875)