The Experts below are selected from a list of 1857 Experts worldwide ranked by ideXlab platform
Matthew E Falagas - One of the best experts on this subject based on the ideXlab platform.
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fever and Periorbital Edema a review
Survey of Ophthalmology, 2007Co-Authors: Petros I Rafailidis, Matthew E FalagasAbstract:Fever and Periorbital swelling are the manifestation of a broad array of diseases. Among them are emergency situations, which need prompt physician input. Swiftly formulating a differential diagnosis approach is crucial. Diseases causing fever and Periorbital Edema are either local or systemic. Nevertheless, their impact can be systemic if they evade diagnosis. Infectious diseases and non-infectious diseases (inflammatory and allergic diseases, autoimmune diseases, neoplastic diseases, and trauma) can all lead to fever and Periorbital Edema. A meticulous history and physical examination in association with targeted tests against the presented spectrum of diseases (specific serological tests, radiological tests, cultures taken from the surface of the Periorbital area and other relevant areas, and skin biopsy for histological and microbiological examination) will clarify the diagnosis.
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REVIEWS IN MEDICINE
2007Co-Authors: Robert Weinberg, Petros I Rafailidis, Matthew E FalagasAbstract:Fever and Periorbital swelling are the manifestation of a broad array of diseases. Among them are emergency situations, which need prompt physician input. Swiftly formulating a differential diagnosis approach is crucial. Diseases causing fever and Periorbital Edema are either local or systemic. Nevertheless, their impact can be systemic if they evade diagnosis. Infectious diseases and non- infectious diseases (inflammatory and allergic diseases, autoimmune diseases, neoplastic diseases, and trauma) can all lead to fever and Periorbital Edema. A meticulous history and physical examination in association with targeted tests against the presented spectrum of diseases (specific serological tests, radiological tests, cultures taken from the surface of the Periorbital area and other relevant areas, and skin biopsy for histological and microbiological examination) will clarify the diagnosis. (Surv
Philip L Custer - One of the best experts on this subject based on the ideXlab platform.
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Periorbital Edema secondary to imatinib mesylate
Clinical Ophthalmology, 2010Co-Authors: Collin M Mcclelland, George J Harocopos, Philip L CusterAbstract:Imatinib mesylate (Gleevec®) is a well-established pharmacologic treatment for all phases of chronic myeloid leukemia and for advanced gastrointestinal stromal tumors (GISTs). Edema-related side effects are relatively common in imatinib therapy with the periocular skin representing one of the most common sites for localized Edema. While the adverse effect of Periorbital Edema with imatinib is well documented in the oncology literature, there is limited reference to this common reaction in the ophthalmology literature. We report two patients with upper eyelid Edema associated with imatinib therapy who required surgical intervention to ameliorate significant visual field obstruction. We highlight the details of each case including the histopathologic findings of excised redundant skin followed by a thorough review of the literature on imatinib related Periorbital Edema.
Bruce Freundlich - One of the best experts on this subject based on the ideXlab platform.
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bilateral Periorbital Edema in systemic lupus erythematosus
The Journal of Rheumatology, 1993Co-Authors: D Norden, J Weinberg, H R Schumacher, G Keenan, Bruce FreundlichAbstract:Periorbital Edema is a rare manifestation of systemic lupus erythematosus (SLE). We describe a patient with SLE who developed bilateral Periorbital Edema during her lupus flares. Conjunctival biopsy confirmed the presence of inflammation. Resolution incurred only after high doses of corticosteroids. The differential diagnosis of Periorbital Edema and possible etiologies of the Edema are briefly discussed
D M P Thomson - One of the best experts on this subject based on the ideXlab platform.
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localized unilateral Periorbital Edema induced by aspirin
Annals of Allergy Asthma & Immunology, 1997Co-Authors: Kursteen S Price, D M P ThomsonAbstract:Background Aspirin intolerance manifested as bronchospasm or urticaria/angioEdema has been observed since the beginning of this century. Objective To report a novel case of intolerance to aspirin ingestion. Methods Case report; routine skin testing; pulmonary function testing; aspirin challenge. Results A 30-year-old man with a history of left ocular trauma at the age of 10 noted a 3-year history of left Periorbital angioEdema after aspirin but not other nonsteroidal anti-inflammatory drugs. Incremental oral aspirin challenge resulted in this unilateral symptomatology at a dose of 673 mg. Conclusion To the best of our knowledge, this is the first reported case of unilateral Periorbital Edema following aspirin ingestion.
James K. Mangan - One of the best experts on this subject based on the ideXlab platform.
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dose related Periorbital Edema following sorafenib in a patient with acute myeloid leukemia
Journal of Oncology Pharmacy Practice, 2019Co-Authors: Craig W. Freyer, James K. ManganAbstract:We describe a case of dose-related Periorbital Edema in a patient with FLT3-mutated acute myeloid leukemia taking sorafenib and voriconazole that resolved following sorafenib dose reduction. We hypothesize that the mechanism of this adverse event may be related to the inhibition of platelet-derived growth factor receptor (PDGFR) by sorafenib. Clinicians should be aware of this possible dose-related adverse event and the potential role of sorafenib dose reduction when on concurrent voriconazole.
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Dose-related Periorbital Edema following sorafenib in a patient with acute myeloid leukemia:
Journal of Oncology Pharmacy Practice, 2018Co-Authors: Craig W. Freyer, James K. ManganAbstract:We describe a case of dose-related Periorbital Edema in a patient with FLT3-mutated acute myeloid leukemia taking sorafenib and voriconazole that resolved following sorafenib dose reduction. We hyp...