The Experts below are selected from a list of 6333 Experts worldwide ranked by ideXlab platform
Herta Flor - One of the best experts on this subject based on the ideXlab platform.
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Phantom Limb perception interferes with motor imagery after unilateral upper Limb amputation
Scientific Reports, 2016Co-Authors: Yuanyuan Lyu, Herta Flor, Robin Bekraterbodmann, Xiaoli Guo, Shanbao TongAbstract:A potential contributor to impaired motor imagery in amputees is an alteration of the body schema as a result of the presence of a Phantom Limb. However, the nature of the relationship between motor imagery and Phantom experiences remains unknown. In this study, the influence of Phantom Limb perception on motor imagery was investigated using a hand mental rotation task by means of behavioral and electrophysiological measures. Compared with healthy controls, significantly prolonged response time for both the intact and missing hand were observed specifically in amputees who perceived a Phantom Limb during the task but not in amputees without Phantom Limb perception. Event-related desynchronization of EEG in the beta band (beta-ERD) in central and parietal areas showed an angular disparity specifically in amputees with Phantom Limb perception, with its source localized in the right inferior parietal lobule. The response time as well as the beta-ERD values were significantly positively correlated with Phantom vividness. Our results suggest that Phantom Limb perception during the task is an important interferential factor for motor imagery after amputation and the interference might be related to a change of the body representation resulting from an unnatural posture of the Phantom Limb.
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Phantom Limb Pain
2016Co-Authors: Herta Flor, Xaver FuchsAbstract:Phantom Limb pain occurs following Limb amputations and is characterzed by pain emanating from the no longer existing Limb. In many cases, this problem develops into pervasive chronic pain impairing the amputees' quality of life. In this article, we describe phenomena observable in amputees and distinguish Phantom Limb pain from non-painful Phantom Limb sensations, referred sensations and residual Limb pain. We review and discuss research on both the role of the peripheral and the central nervous system and of how they interact with psychological factors. Clinical implications and treatment approaches based on these mechanisms are discussed.
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Phantom Limb pain. Psychological treatment strategies
Schmerz (Berlin Germany), 2013Co-Authors: Martin Diers, Herta FlorAbstract:Similar to other pain syndromes Phantom Limb pain is characterized by learning and memory processes that maintain the pain and increase maladaptive plastic changes of the brain: therefore, psychological interventions that change maladaptive memory processes are useful. In addition to traditional psychological interventions, such as pain management training and biofeedback, more recent developments that involve sensory discrimination training, mirror treatment, graded motor imagery, prosthesis training and training in virtual reality are interesting. These interventions not only reduce Phantom Limb pain but also reverse the associated maladaptive brain changes.
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Phantom Limb pain after lower Limb trauma origins and treatments
The International Journal of Lower Extremity Wounds, 2011Co-Authors: Jens Foell, Herta Flor, Robin Bekraterbodmann, Jonathan ColeAbstract:Phantom sensations, that is, sensations perceived in a body part that has been lost, are a common consequence of accidental or clinical extremity amputations. Most amputation patients report a continuing presence of the Limb, with some describing additional sensations such as numbness, tickling, or cramping of the Phantom Limb. The type, frequency, and stability of these Phantom sensations can vary immensely. The phenomenon of painful Phantom sensations, that is, Phantom Limb pain, presents a challenge for practitioners and researchers and is often detrimental to the patient’s quality of life. In addition to the use of conventional therapies for chronic pain disorders, recent years have seen the development of novel treatments for Phantom Limb pain, based on an increasing body of research on neurophysiological changes after amputation. This article describes the current state of research in regard to the demographics, causal factors, and treatments of Phantom Limb pain.
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Phantom Limb pain characteristics causes and treatment
Lancet Neurology, 2002Co-Authors: Herta FlorAbstract:Phantom-Limb pain is a common sequela of amputation, occurring in up to 80% of people who undergo the procedure. It must be differentiated from non-painful Phantom phenomena, residual-Limb pain, and non-painful residual-Limb phenomena. Central changes seem to be a major determinant of Phantom-Limb pain; however, peripheral and psychological factors may contribute to it. A comprehensive model of Phantom-Limb pain is presented that assigns major roles to pain occurring before the amputation and to central as well as peripheral changes related to it. So far, few mechanism-based treatments for Phantom-Limb pain have been proposed. Most published reports are based on anecdotal evidence. Interventions targeting central changes seem promising. The prevention of Phantom-Limb pain by peripheral analgesia has not yielded consistent results. Additional measures that reverse or prevent the formation of central memory processes might be more effective.
Gyorgy Levay - One of the best experts on this subject based on the ideXlab platform.
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sensory stimulation enhances Phantom Limb perception and movement decoding
Journal of Neural Engineering, 2020Co-Authors: Luke Osborn, Keqin Ding, Mark Hays, Rohit Bose, Mark M Iskarous, Andrei Dragomir, Zied Tayeb, Gyorgy LevayAbstract:Objective. A major challenge for controlling a prosthetic arm is communication between the device and the user's Phantom Limb. We show the ability to enhance Phantom Limb perception and improve movement decoding through targeted transcutaneous electrical nerve stimulation in individuals with an arm amputation. Approach. Transcutaneous nerve stimulation experiments were performed with four participants with arm amputation to map Phantom Limb perception. We measured myoelectric signals during Phantom hand movements before and after participants received sensory stimulation. Using electroencephalogram (EEG) monitoring, we measured the neural activity in sensorimotor regions during Phantom movements and stimulation. In one participant, we also tracked sensory mapping over 2 years and movement decoding performance over 1 year. Main results. Results show improvements in the participants' ability to perceive and move the Phantom hand as a result of sensory stimulation, which leads to improved movement decoding. In the extended study with one participant, we found that sensory mapping remains stable over 2 years. Sensory stimulation improves within-day movement decoding while performance remains stable over 1 year. From the EEG, we observed cortical correlates of sensorimotor integration and increased motor-related neural activity as a result of enhanced Phantom Limb perception. Significance. This work demonstrates that Phantom Limb perception influences prosthesis control and can benefit from targeted nerve stimulation. These findings have implications for improving prosthesis usability and function due to a heightened sense of the Phantom hand.
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sensory stimulation enhances Phantom Limb perception and movement decoding
medRxiv, 2020Co-Authors: Luke Osborn, Keqin Ding, Mark Hays, Rohit Bose, Mark M Iskarous, Andrei Dragomir, Zied Tayeb, Gyorgy Levay, Christopher L Hunt, Gordon ChengAbstract:Objective. A major challenge for controlling a prosthetic arm is communication between the device and the user9s Phantom Limb. We show the ability to enhance amputees9 Phantom Limb perception and improve movement decoding through targeted transcutaneous electrical nerve stimulation (tTENS). Approach. Transcutaneous nerve stimulation experiments were performed with four amputee participants to map Phantom Limb perception. We measured myoelectric signals during Phantom hand movements before and after amputees received sensory stimulation. Using electroencephalogram (EEG) monitoring, we measure the neural activity in sensorimotor regions during Phantom movements and stimulation. In one participant, we also tracked sensory mapping over 2 years and movement decoding performance over 1 year. Main results. Results show improvements in the amputees9 ability to perceive and move the Phantom hand as a result of sensory stimulation, which leads to improved movement decoding. In the extended study with one amputee, we found that sensory mapping remains stable over 2 years. Remarkably, sensory stimulation improves within-day movement decoding while performance remains stable over 1 year. From the EEG, we observed cortical correlates of sensorimotor integration and increased motor-related neural activity as a result of enhanced Phantom Limb perception. Significance. This work demonstrates that Phantom Limb perception influences prosthesis control and can benefit from targeted nerve stimulation. These findings have implications for improving prosthesis usability and function due to a heightened sense of the Phantom hand.
Rohit Bose - One of the best experts on this subject based on the ideXlab platform.
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sensory stimulation enhances Phantom Limb perception and movement decoding
Journal of Neural Engineering, 2020Co-Authors: Luke Osborn, Keqin Ding, Mark Hays, Rohit Bose, Mark M Iskarous, Andrei Dragomir, Zied Tayeb, Gyorgy LevayAbstract:Objective. A major challenge for controlling a prosthetic arm is communication between the device and the user's Phantom Limb. We show the ability to enhance Phantom Limb perception and improve movement decoding through targeted transcutaneous electrical nerve stimulation in individuals with an arm amputation. Approach. Transcutaneous nerve stimulation experiments were performed with four participants with arm amputation to map Phantom Limb perception. We measured myoelectric signals during Phantom hand movements before and after participants received sensory stimulation. Using electroencephalogram (EEG) monitoring, we measured the neural activity in sensorimotor regions during Phantom movements and stimulation. In one participant, we also tracked sensory mapping over 2 years and movement decoding performance over 1 year. Main results. Results show improvements in the participants' ability to perceive and move the Phantom hand as a result of sensory stimulation, which leads to improved movement decoding. In the extended study with one participant, we found that sensory mapping remains stable over 2 years. Sensory stimulation improves within-day movement decoding while performance remains stable over 1 year. From the EEG, we observed cortical correlates of sensorimotor integration and increased motor-related neural activity as a result of enhanced Phantom Limb perception. Significance. This work demonstrates that Phantom Limb perception influences prosthesis control and can benefit from targeted nerve stimulation. These findings have implications for improving prosthesis usability and function due to a heightened sense of the Phantom hand.
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sensory stimulation enhances Phantom Limb perception and movement decoding
medRxiv, 2020Co-Authors: Luke Osborn, Keqin Ding, Mark Hays, Rohit Bose, Mark M Iskarous, Andrei Dragomir, Zied Tayeb, Gyorgy Levay, Christopher L Hunt, Gordon ChengAbstract:Objective. A major challenge for controlling a prosthetic arm is communication between the device and the user9s Phantom Limb. We show the ability to enhance amputees9 Phantom Limb perception and improve movement decoding through targeted transcutaneous electrical nerve stimulation (tTENS). Approach. Transcutaneous nerve stimulation experiments were performed with four amputee participants to map Phantom Limb perception. We measured myoelectric signals during Phantom hand movements before and after amputees received sensory stimulation. Using electroencephalogram (EEG) monitoring, we measure the neural activity in sensorimotor regions during Phantom movements and stimulation. In one participant, we also tracked sensory mapping over 2 years and movement decoding performance over 1 year. Main results. Results show improvements in the amputees9 ability to perceive and move the Phantom hand as a result of sensory stimulation, which leads to improved movement decoding. In the extended study with one amputee, we found that sensory mapping remains stable over 2 years. Remarkably, sensory stimulation improves within-day movement decoding while performance remains stable over 1 year. From the EEG, we observed cortical correlates of sensorimotor integration and increased motor-related neural activity as a result of enhanced Phantom Limb perception. Significance. This work demonstrates that Phantom Limb perception influences prosthesis control and can benefit from targeted nerve stimulation. These findings have implications for improving prosthesis usability and function due to a heightened sense of the Phantom hand.
Andrei Dragomir - One of the best experts on this subject based on the ideXlab platform.
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sensory stimulation enhances Phantom Limb perception and movement decoding
Journal of Neural Engineering, 2020Co-Authors: Luke Osborn, Keqin Ding, Mark Hays, Rohit Bose, Mark M Iskarous, Andrei Dragomir, Zied Tayeb, Gyorgy LevayAbstract:Objective. A major challenge for controlling a prosthetic arm is communication between the device and the user's Phantom Limb. We show the ability to enhance Phantom Limb perception and improve movement decoding through targeted transcutaneous electrical nerve stimulation in individuals with an arm amputation. Approach. Transcutaneous nerve stimulation experiments were performed with four participants with arm amputation to map Phantom Limb perception. We measured myoelectric signals during Phantom hand movements before and after participants received sensory stimulation. Using electroencephalogram (EEG) monitoring, we measured the neural activity in sensorimotor regions during Phantom movements and stimulation. In one participant, we also tracked sensory mapping over 2 years and movement decoding performance over 1 year. Main results. Results show improvements in the participants' ability to perceive and move the Phantom hand as a result of sensory stimulation, which leads to improved movement decoding. In the extended study with one participant, we found that sensory mapping remains stable over 2 years. Sensory stimulation improves within-day movement decoding while performance remains stable over 1 year. From the EEG, we observed cortical correlates of sensorimotor integration and increased motor-related neural activity as a result of enhanced Phantom Limb perception. Significance. This work demonstrates that Phantom Limb perception influences prosthesis control and can benefit from targeted nerve stimulation. These findings have implications for improving prosthesis usability and function due to a heightened sense of the Phantom hand.
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sensory stimulation enhances Phantom Limb perception and movement decoding
medRxiv, 2020Co-Authors: Luke Osborn, Keqin Ding, Mark Hays, Rohit Bose, Mark M Iskarous, Andrei Dragomir, Zied Tayeb, Gyorgy Levay, Christopher L Hunt, Gordon ChengAbstract:Objective. A major challenge for controlling a prosthetic arm is communication between the device and the user9s Phantom Limb. We show the ability to enhance amputees9 Phantom Limb perception and improve movement decoding through targeted transcutaneous electrical nerve stimulation (tTENS). Approach. Transcutaneous nerve stimulation experiments were performed with four amputee participants to map Phantom Limb perception. We measured myoelectric signals during Phantom hand movements before and after amputees received sensory stimulation. Using electroencephalogram (EEG) monitoring, we measure the neural activity in sensorimotor regions during Phantom movements and stimulation. In one participant, we also tracked sensory mapping over 2 years and movement decoding performance over 1 year. Main results. Results show improvements in the amputees9 ability to perceive and move the Phantom hand as a result of sensory stimulation, which leads to improved movement decoding. In the extended study with one amputee, we found that sensory mapping remains stable over 2 years. Remarkably, sensory stimulation improves within-day movement decoding while performance remains stable over 1 year. From the EEG, we observed cortical correlates of sensorimotor integration and increased motor-related neural activity as a result of enhanced Phantom Limb perception. Significance. This work demonstrates that Phantom Limb perception influences prosthesis control and can benefit from targeted nerve stimulation. These findings have implications for improving prosthesis usability and function due to a heightened sense of the Phantom hand.
Luke Osborn - One of the best experts on this subject based on the ideXlab platform.
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sensory stimulation enhances Phantom Limb perception and movement decoding
Journal of Neural Engineering, 2020Co-Authors: Luke Osborn, Keqin Ding, Mark Hays, Rohit Bose, Mark M Iskarous, Andrei Dragomir, Zied Tayeb, Gyorgy LevayAbstract:Objective. A major challenge for controlling a prosthetic arm is communication between the device and the user's Phantom Limb. We show the ability to enhance Phantom Limb perception and improve movement decoding through targeted transcutaneous electrical nerve stimulation in individuals with an arm amputation. Approach. Transcutaneous nerve stimulation experiments were performed with four participants with arm amputation to map Phantom Limb perception. We measured myoelectric signals during Phantom hand movements before and after participants received sensory stimulation. Using electroencephalogram (EEG) monitoring, we measured the neural activity in sensorimotor regions during Phantom movements and stimulation. In one participant, we also tracked sensory mapping over 2 years and movement decoding performance over 1 year. Main results. Results show improvements in the participants' ability to perceive and move the Phantom hand as a result of sensory stimulation, which leads to improved movement decoding. In the extended study with one participant, we found that sensory mapping remains stable over 2 years. Sensory stimulation improves within-day movement decoding while performance remains stable over 1 year. From the EEG, we observed cortical correlates of sensorimotor integration and increased motor-related neural activity as a result of enhanced Phantom Limb perception. Significance. This work demonstrates that Phantom Limb perception influences prosthesis control and can benefit from targeted nerve stimulation. These findings have implications for improving prosthesis usability and function due to a heightened sense of the Phantom hand.
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sensory stimulation enhances Phantom Limb perception and movement decoding
medRxiv, 2020Co-Authors: Luke Osborn, Keqin Ding, Mark Hays, Rohit Bose, Mark M Iskarous, Andrei Dragomir, Zied Tayeb, Gyorgy Levay, Christopher L Hunt, Gordon ChengAbstract:Objective. A major challenge for controlling a prosthetic arm is communication between the device and the user9s Phantom Limb. We show the ability to enhance amputees9 Phantom Limb perception and improve movement decoding through targeted transcutaneous electrical nerve stimulation (tTENS). Approach. Transcutaneous nerve stimulation experiments were performed with four amputee participants to map Phantom Limb perception. We measured myoelectric signals during Phantom hand movements before and after amputees received sensory stimulation. Using electroencephalogram (EEG) monitoring, we measure the neural activity in sensorimotor regions during Phantom movements and stimulation. In one participant, we also tracked sensory mapping over 2 years and movement decoding performance over 1 year. Main results. Results show improvements in the amputees9 ability to perceive and move the Phantom hand as a result of sensory stimulation, which leads to improved movement decoding. In the extended study with one amputee, we found that sensory mapping remains stable over 2 years. Remarkably, sensory stimulation improves within-day movement decoding while performance remains stable over 1 year. From the EEG, we observed cortical correlates of sensorimotor integration and increased motor-related neural activity as a result of enhanced Phantom Limb perception. Significance. This work demonstrates that Phantom Limb perception influences prosthesis control and can benefit from targeted nerve stimulation. These findings have implications for improving prosthesis usability and function due to a heightened sense of the Phantom hand.