The Experts below are selected from a list of 15 Experts worldwide ranked by ideXlab platform

Luis E Cuca - One of the best experts on this subject based on the ideXlab platform.

  • fingerprint analysis of unfractionated Piper Plant extracts by hplc uv dad coupled with chemometric methods
    Journal of The Chilean Chemical Society, 2012
    Co-Authors: Freddy A Bernal, Wilman A Delgado, Luis E Cuca
    Abstract:

    crude ethanolic extracts of Piper Plants were analyzed by combining HPLC fingerprints and chemometric methods including principal component analysis (PCA), hierarchical clustering analysis (HCA) and parallel factor analysis (PARAFAC). All statistical analysis were carried out both with and without previous preprocessing by counting with alignment of the fingerprints by correlation optimized warping (COW) and several normalization methods. Normalization processes of autoscaling, range scaling and vast scaling resulted to be the better offering the most relevant information. Both direct two-way methods (PCA and HCA) and HCA after data minimization employing a three-way method (PARAFAC) were demonstrated to be useful in the establishment of chemical composition relationships among Piper samples, and resulting in agreement with phylogenic relationships previously reported in literature to some Piper species. . So, at present botanical products are being accepted as prominent alternatives for pests control. However, the biopotential of crude extracts as pest controllers is determined by chemical composition of the source Plant, so that a possibility to search new Plant extracts possessing a determined biological activity can be based on comparison of secondary metabolites profiles obtained by high resolution separation techniques (CG, HPLC, etc.) with those to previously verify active extracts, mainly using different statistical tools (principal component analysis, hierarchical clustering, similarity analysis, etc.), which can include analysis of n-way matrices (PARAFAC, Tucker, etc.), depending on acquired data. Therefore, by continuing our research on Colombian higher Plants 9 , in this paper are presented chromatographic and chemometric analysis of Piper Plant extracts without any pretreatment by multi-wavelength-HPLC (the simplest hyphenated technique to characterization of Plant natural products 10 ), including a comparison of results to PCA and HCA analysis to integrated HPLC profiles with results of PARAFAC and HCA analysis to HPLC-UV-DAD profiles, both with and without different data preprocessing (alignment and several normalization processes).

Freddy A Bernal - One of the best experts on this subject based on the ideXlab platform.

  • fingerprint analysis of unfractionated Piper Plant extracts by hplc uv dad coupled with chemometric methods
    Journal of The Chilean Chemical Society, 2012
    Co-Authors: Freddy A Bernal, Wilman A Delgado, Luis E Cuca
    Abstract:

    crude ethanolic extracts of Piper Plants were analyzed by combining HPLC fingerprints and chemometric methods including principal component analysis (PCA), hierarchical clustering analysis (HCA) and parallel factor analysis (PARAFAC). All statistical analysis were carried out both with and without previous preprocessing by counting with alignment of the fingerprints by correlation optimized warping (COW) and several normalization methods. Normalization processes of autoscaling, range scaling and vast scaling resulted to be the better offering the most relevant information. Both direct two-way methods (PCA and HCA) and HCA after data minimization employing a three-way method (PARAFAC) were demonstrated to be useful in the establishment of chemical composition relationships among Piper samples, and resulting in agreement with phylogenic relationships previously reported in literature to some Piper species. . So, at present botanical products are being accepted as prominent alternatives for pests control. However, the biopotential of crude extracts as pest controllers is determined by chemical composition of the source Plant, so that a possibility to search new Plant extracts possessing a determined biological activity can be based on comparison of secondary metabolites profiles obtained by high resolution separation techniques (CG, HPLC, etc.) with those to previously verify active extracts, mainly using different statistical tools (principal component analysis, hierarchical clustering, similarity analysis, etc.), which can include analysis of n-way matrices (PARAFAC, Tucker, etc.), depending on acquired data. Therefore, by continuing our research on Colombian higher Plants 9 , in this paper are presented chromatographic and chemometric analysis of Piper Plant extracts without any pretreatment by multi-wavelength-HPLC (the simplest hyphenated technique to characterization of Plant natural products 10 ), including a comparison of results to PCA and HCA analysis to integrated HPLC profiles with results of PARAFAC and HCA analysis to HPLC-UV-DAD profiles, both with and without different data preprocessing (alignment and several normalization processes).

Wilman A Delgado - One of the best experts on this subject based on the ideXlab platform.

  • fingerprint analysis of unfractionated Piper Plant extracts by hplc uv dad coupled with chemometric methods
    Journal of The Chilean Chemical Society, 2012
    Co-Authors: Freddy A Bernal, Wilman A Delgado, Luis E Cuca
    Abstract:

    crude ethanolic extracts of Piper Plants were analyzed by combining HPLC fingerprints and chemometric methods including principal component analysis (PCA), hierarchical clustering analysis (HCA) and parallel factor analysis (PARAFAC). All statistical analysis were carried out both with and without previous preprocessing by counting with alignment of the fingerprints by correlation optimized warping (COW) and several normalization methods. Normalization processes of autoscaling, range scaling and vast scaling resulted to be the better offering the most relevant information. Both direct two-way methods (PCA and HCA) and HCA after data minimization employing a three-way method (PARAFAC) were demonstrated to be useful in the establishment of chemical composition relationships among Piper samples, and resulting in agreement with phylogenic relationships previously reported in literature to some Piper species. . So, at present botanical products are being accepted as prominent alternatives for pests control. However, the biopotential of crude extracts as pest controllers is determined by chemical composition of the source Plant, so that a possibility to search new Plant extracts possessing a determined biological activity can be based on comparison of secondary metabolites profiles obtained by high resolution separation techniques (CG, HPLC, etc.) with those to previously verify active extracts, mainly using different statistical tools (principal component analysis, hierarchical clustering, similarity analysis, etc.), which can include analysis of n-way matrices (PARAFAC, Tucker, etc.), depending on acquired data. Therefore, by continuing our research on Colombian higher Plants 9 , in this paper are presented chromatographic and chemometric analysis of Piper Plant extracts without any pretreatment by multi-wavelength-HPLC (the simplest hyphenated technique to characterization of Plant natural products 10 ), including a comparison of results to PCA and HCA analysis to integrated HPLC profiles with results of PARAFAC and HCA analysis to HPLC-UV-DAD profiles, both with and without different data preprocessing (alignment and several normalization processes).

Sungeun Lee - One of the best experts on this subject based on the ideXlab platform.

  • naturally occurring Piper Plant amides potential in agricultural and pharmaceutical industries perspectives of Piperine and Piperlongumine
    Applied Biological Chemistry, 2019
    Co-Authors: Hwangju Jeon, Kyeongnam Kim, Y S Kim, Sungeun Lee
    Abstract:

    Piperaceae Plants consist of about 3600 species, of which about 2000 are Piper Plants. Their habitat is distributed across pantropical regions. The representative Plant is Piper nigrum, known as black pepper. These Plants have been widely used in folk medicine in Korean traditional medicine. This review collected papers identifying and separating the amides obtained from these Piper Plants, with a focus on Piper amides potential to control the production and growth of fungal strains that cause Plant disease and their insecticidal properties against agricultural pests. Piper amide benefits include antiaflatoxigenic activities, antiparasitic activities, anticancer properties, antiplatelet activities, and anti-inflammatory activities, among other therapeutic properties for the treatment of human diseases. In addition, this review paper provides a total synthesis study on the mass production of Piper amides and their derivatives, with a formulation study for industrial use. This review paper is designed to help inform future studies on Piper amide applications.

Mohd Nazir, Syaza Sailah - One of the best experts on this subject based on the ideXlab platform.

  • Antibacterial activities of Piper sarmentosum (kaduk) methanolic extract
    'Department of Biology (UPM)', 2019
    Co-Authors: Ibrahim, Maizatul Akma, Mohd Nazir, Syaza Sailah
    Abstract:

    Piper sarmentosum or locally known as Kaduk is a tropical herbal Plant that is well established for many traditional medicinal purposes. The antibacterial properties of methanolic extract for P. sarmentosum leaves have been investigated in this study. From the disc diffusion test, the methanolic extract of P. sarmentosum was found to be active against Gram-positive bacteria namely Staphylococcus saprophyticus (ATCC 15305) and Staphylococcus aureus (ATCC 25923) with zone of inhibition at 17.1 and 11.3 mm, respectively. Meanwhile, the extract showed no or minimal activity against Gram-negative bacteria (Klebsiella pneumoniae ATCC 700603, Pseudomonas aeroginosa ATCC 27853, Enterococcus aerogenes ATCC 13048, Shigella flexneri IMR S 430/07 B, Salmonella typhimurium IMR S 974/05 B) as well as Gram-positive bacteria of Bacillus subtilis (IMR B145/11C). Accordingly, further study by Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were conducted on S. saprophyticus and S. Aureus. The MIC value of methanolic extract for the tested S. saprophyticus and S. aureus were both at 7.5 mg/mL. The MBC showed bacteriostatic for S. saprophyticus and S. aureus at 15 mg/mL. The result of this study indicated that this Piper Plant extract can be potential antibacterial agent in the future if the active component can be identified