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Oliver Findl - One of the best experts on this subject based on the ideXlab platform.

  • Posterior Capsule opacification and capsular bag performance of a microincision intraocular lens
    Journal of Cataract and Refractive Surgery, 2011
    Co-Authors: Vinod Gangwani, Nino Hirnschall, John Koshy, Alja Crnej, Yutaro Nishi, Vincenzo Maurino, Oliver Findl
    Abstract:

    Purpose To assess the axial stability and Posterior Capsule opacification (PCO)–inhibiting efficacy of a microincision hydrophilic intraocular lens (IOL) (Idea 613 XC) and a standard hydrophobic open-loop acrylic IOL (Acrysof SA60AT). Setting Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom. Design Clinical trial. Methods Patients with bilateral cataract received a microincision cataract surgery (MICS) IOL in 1 eye and a small-incision cataract surgery (SICS) IOL in the contralateral eye. Follow-up examinations were performed immediately after surgery and postoperatively at 1 week and 3 and 24 months. Posterior Capsule opacification was assessed using retroillumination photography. Anterior chamber depth (ACD) was measured using partial coherence laser interferometry, and IOL tilt and decentration were measured using a Purkinje meter. Results Seventy eyes (35 patients) were enrolled. The mean ACD at 3 months was 4.91 mm ± 0.26 (SD) in the MICS group and 4.60 ± 0.23 mm in the SICS group. The anterior IOL shift over the first 3 months was slightly smaller with the MICS IOL (81 μm) than with the SICS IOL (254 μm). The mean ACD was 0.377 ± 178 μm deeper with the MICS IOL (P Conclusions Two years after surgery, the PCO rate was slightly higher with the MICS IOL. The 2 IOLs had similar performance in terms of axial stability, decentration, and tilt. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes.

  • Posterior Capsule opacification and capsular bag performance of a microincision intraocular lens
    Journal of Cataract and Refractive Surgery, 2011
    Co-Authors: Vinod Gangwani, Nino Hirnschall, John Koshy, Alja Crnej, Yutaro Nishi, Vincenzo Maurino, Oliver Findl
    Abstract:

    Purpose To assess the axial stability and Posterior Capsule opacification (PCO)–inhibiting efficacy of a microincision hydrophilic intraocular lens (IOL) (Idea 613 XC) and a standard hydrophobic open-loop acrylic IOL (Acrysof SA60AT). Setting Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom. Design Clinical trial. Methods Patients with bilateral cataract received a microincision cataract surgery (MICS) IOL in 1 eye and a small-incision cataract surgery (SICS) IOL in the contralateral eye. Follow-up examinations were performed immediately after surgery and postoperatively at 1 week and 3 and 24 months. Posterior Capsule opacification was assessed using retroillumination photography. Anterior chamber depth (ACD) was measured using partial coherence laser interferometry, and IOL tilt and decentration were measured using a Purkinje meter. Results Seventy eyes (35 patients) were enrolled. The mean ACD at 3 months was 4.91 mm ± 0.26 (SD) in the MICS group and 4.60 ± 0.23 mm in the SICS group. The anterior IOL shift over the first 3 months was slightly smaller with the MICS IOL (81 μm) than with the SICS IOL (254 μm). The mean ACD was 0.377 ± 178 μm deeper with the MICS IOL ( P t test). Two years postoperatively, the amount of regeneratory PCO was higher with the MICS IOL than with the SICS IOL (image analysis software score 2.6 versus 1.9; P =.005). Conclusions Two years after surgery, the PCO rate was slightly higher with the MICS IOL. The 2 IOLs had similar performance in terms of axial stability, decentration, and tilt. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes.

  • effect of intraocular lens design on Posterior Capsule opacification
    Journal of Cataract and Refractive Surgery, 2008
    Co-Authors: Wolf Buehl, Oliver Findl
    Abstract:

    Posterior Capsule opacification (PCO) remains the most common long-term complication after cataract surgery. Many studies have attempted to identify factors that influence the development of PCO. The aim of this systematic review based on Cochrane methodology was to summarize the effects of intraocular lens (IOL) geometry, including modifications of the IOL optic (especially optic edge design) and haptics, on the development of PCO. Twenty-six prospective randomized controlled trials with a follow-up of at least 12 months were included. In 5 of 7 studies, visual acuity was better in sharp-edged IOLs than in round-edged IOL. The PCO score was significantly lower with sharp-edged IOLs but did not differ significantly between 1-piece and 3-piece open-loop IOLs. Because of the significant difference in the PCO score, sharp-edged IOL optics should be preferred to round-edged IOL optics.

  • long term effect of 1 piece and 3 piece hydrophobic acrylic intraocular lens on Posterior Capsule opacification a randomized trial
    Ophthalmology, 2007
    Co-Authors: Christina Leydolt, Wolf Buehl, Rupert Menapace, Sofija Davidovic, Stefan Sacu, Thomas Neumayer, Ana Prinz, Oliver Findl
    Abstract:

    Purpose To compare the intensity of Posterior Capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants Fifty-two patients with bilateral age-related cataract (104 eyes). Methods Each study patient had cataract surgery in both eyes and received a 1-piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of Posterior Capsule opacification (score range, 0–10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure Posterior Capsule opacification score (scale, 0–10). Results There was no significant difference between the 1-piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior Capsule opacification, and Posterior Capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium–aluminium–garnet laser treatment rate 5 years after surgery.

  • long term changes in the morphology of Posterior Capsule opacification
    Journal of Cataract and Refractive Surgery, 2005
    Co-Authors: Thomas Neumayer, Oliver Findl, Wolf Buehl, Rupert Menapace, Stefan Sacu, Michael Georgopoulos
    Abstract:

    Purpose To classify the morphologic appearance of Posterior Capsule opacification (PCO) and to observe and document the changes over longer periods of time. Setting Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods Eighty-one pseudophakic eyes of 53 patients with PCO of varying degrees were included in this prospective study. Digital retroillumination images of the Posterior Capsule were taken in a standardized fashion 1, 2, and 3 years after cataract surgery. The PCO morphology was classified, and changes among the 3 follow-up images were analyzed. Results At 1, 2, and 3 years, pearls occurred in 16 (20%), 41 (51%), and 57 (63%) eyes. Pearls increased in size and number. Cases with thin layers of PCO decreased from 53 to 33 to 16 eyes. Conversely, cases with thick layers increased from 18 to 45 and 64 eyes. “Cheese holes” appeared most frequently as the predominant structure (range 47% to 51%), followed by plates (range 28% to 31%), islands (range 15% to 20%), and traces of PCO (range 1% to 5%). Changes in expansion of the PCO area were observed in 61 eyes (75%) during period 1 (1 to 2 years) and period 2 (2 to 3 years). Regions of expansion and regression in the same eye occurred in periods 1 and 2 in 11 eyes (14%) and 9 eyes (11%), respectively. The phenomenon of thinning bridges, a regression of syncytial extensions of PCO, occurred in 22 eyes (27%) and 32 eyes (40%), respectively. An overlapping growth of 2 layers was observed in 18 eyes (22%). Conclusions The morphology of PCO is multifaceted. Apart from the Elschnig pearls, categories such as cheese holes, plates, islands, and traces of PCO were distinguished. Over the years, pearls increased in frequency, size, and number. Expansion and regression occurred simultaneously in some cases. Two or more layers grew on top of each other in some eyes.

Karsten König - One of the best experts on this subject based on the ideXlab platform.

  • in vitro femtosecond laser assisted nanosurgery of porcine Posterior Capsule
    Journal of Cataract and Refractive Surgery, 2008
    Co-Authors: Sergey Toropygin, Berthold Seitz, Pedro Mestres, Iris Riemann, Klaus W. Ruprecht, M Krause, Karsten König
    Abstract:

    Purpose To investigate femtosecond laser–assisted nanosurgery of the Posterior Capsule in a prospective in vitro animal study. Setting Department of Ophthalmology and Eye Hospital, University of Saarland, Homburg, and Fraunhofer Institute for Biomedical Engineering, St. Ingbert, Germany. Methods The Posterior Capsules of 12 porcine eyes were irradiated with a nonamplified 90 MHz near-infrared 750 nm titanium:sapphire femtosecond laser. Intratissue and superficial laser cuts of laser-ablated (5 Capsules) and control (1 Capsule) specimens were examined by femtosecond multiphoton laser scanning microscopy (MLSM) and transmission electron microscopy (TEM). Results Laser exposure time and pulse power determined the width of the lesions, which ranged from 0.69 μm ± 0.19 (SD) to 2.81 ± 0.5 μm. Both MLSM and TEM revealed minimal collateral alterations in the tissue surrounding the laser cuts. Conclusions Nonamplified near-infrared femtosecond laser pulses at low pulse energies may be a promising strategy for precise lamellar noncontact nanosurgery of the Posterior Capsule, with minimal structural collateral damage to surrounding tissue. High-resolution MLSM offers 3-dimensional, noninvasive, nondestructive imaging at submicrometer resolution within seconds before and after ablation.

  • in vitro femtosecond laser assisted nanosurgery of porcine Posterior Capsule
    Journal of Cataract and Refractive Surgery, 2008
    Co-Authors: Sergey Toropygin, Berthold Seitz, Pedro Mestres, Iris Riemann, Klaus W. Ruprecht, M Krause, Karsten König
    Abstract:

    Purpose To investigate femtosecond laser–assisted nanosurgery of the Posterior Capsule in a prospective in vitro animal study. Setting Department of Ophthalmology and Eye Hospital, University of Saarland, Homburg, and Fraunhofer Institute for Biomedical Engineering, St. Ingbert, Germany. Methods The Posterior Capsules of 12 porcine eyes were irradiated with a nonamplified 90 MHz near-infrared 750 nm titanium:sapphire femtosecond laser. Intratissue and superficial laser cuts of laser-ablated (5 Capsules) and control (1 Capsule) specimens were examined by femtosecond multiphoton laser scanning microscopy (MLSM) and transmission electron microscopy (TEM). Results Laser exposure time and pulse power determined the width of the lesions, which ranged from 0.69 μm ± 0.19 (SD) to 2.81 ± 0.5 μm. Both MLSM and TEM revealed minimal collateral alterations in the tissue surrounding the laser cuts. Conclusions Nonamplified near-infrared femtosecond laser pulses at low pulse energies may be a promising strategy for precise lamellar noncontact nanosurgery of the Posterior Capsule, with minimal structural collateral damage to surrounding tissue. High-resolution MLSM offers 3-dimensional, noninvasive, nondestructive imaging at submicrometer resolution within seconds before and after ablation.

Abhay R Vasavada - One of the best experts on this subject based on the ideXlab platform.

  • Posterior Capsule opacification after lens implantation incidence risk factors and management
    Expert Review of Ophthalmology, 2013
    Co-Authors: Abhay R Vasavada, Gauri D. Shah, Shetal M Raj, Mayank A Nanavaty
    Abstract:

    Postoperative capsular opacification is a multifactorial physiological consequence of cataract surgery. Opacification involving the central Posterior Capsule has a significant impact on high- and low-contrast acuity and low-contrast sensitivity. The proliferation, migration and abnormal differentiation of residual lens epithelial cells and fibers in the capsular bag have been implicated in the pathogenesis of Posterior Capsule opacification (PCO). The incidence and severity of PCO correlates to the use of surgical techniques, intraocular lens optic edge designs and intraocular lens materials. This article summarizes the clinical studies with recommendations for retarding the development of central PCO. These studies will remain critical for future endeavors undertaken for the eradication of PCO.

  • incidence and influence of Posterior Capsule striae on the development of Posterior Capsule opacification after 1 piece hydrophobic acrylic intraocular lens implantation
    Journal of Cataract and Refractive Surgery, 2012
    Co-Authors: Gauri D. Shah, Alpesh R. Shah, Abhay R Vasavada, M R Praveen, Rupal H Trivedi
    Abstract:

    Purpose To determine the incidence of intraoperative Posterior Capsule striae after implantation of a 1-piece hydrophobic acrylic intraocular lens (IOL), study the clinical impact on the patients’ vision, and assess whether the presence of Posterior Capsule striae increases the risk for Posterior Capsule opacification (PCO). Setting Iladevi Cataract & IOL Research Centre, Ahmedabad, India. Design Case-control study. Methods Part 1 of this study evaluated consecutive adult eyes having cataract surgery performed using standardized techniques with in-the-bag 1-piece hydrophobic acrylic IOL implantation. Posterior Capsule striae details were noted at the end of surgery. Part 2 was a case-control study comprising all patients with intraoperative striae and an age- and biometry-matched control group without striae, which was selected on a 1:1 ratio. Results Intraoperative Posterior Capsule striae were observed in 68 (13.6%) of 500 eyes. A single stria was seen in 43 eyes [63.2%], and multiple striae were seen in 25 eyes [36.7%]). There was no significant difference in logMAR corrected distance visual acuity at baseline ( P =.881) or at 3 years ( P =.191) between cases and controls. At 3 years, there was no statistically significant between-group difference in the median Evaluation of Posterior Capsule Opacification score or area values in the capsulorhexis margin ( P =.36 and P =.39, respectively) or in the central 3.0 mm optic area ( P =.40 and P =.42, respectively). Conclusion The incidence of Posterior Capsule striae was 13.6%. Intraoperative striae did not influence visual acuity or the development of PCO at the 3-year follow-up. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.

  • Comparison of Posterior Capsule opacification with hydrophobic acrylic and hydrophilic acrylic intraocular lenses
    Journal of Cataract and Refractive Surgery, 2011
    Co-Authors: Abhay R Vasavada, Alpesh R. Shah, Gauri D. Shah, Viraj A. Vasavada
    Abstract:

    Purpose To compare Posterior Capsule opacification (PCO) 3 years postoperatively in contralateral eyes with a single-piece hydrophobic acrylic and 1 of 2 single-piece hydrophilic acrylic intraocular lenses (IOLs) with different configurations. Setting Iladevi Cataract and IOL Research Institute, Ahmedabad, India. Design Prospective randomized clinical trial. Methods A hydrophobic Acrysof (hydrophobic group) or a hydrophilic C-flex (hydrophilic group C) or Akreos Adapt IOL (hydrophilic group A) was randomized for implantation in the fellow eye or vice versa of each patient. The Evaluation of Posterior Capsule Opacification (EPCO) area, EPCO score, and neodymium:YAG (Nd:YAG) capsulotomy rates were compared using digital photographs. Results The study enrolled 68 patients. Although there was no significant difference at 1 month, the median EPCO score was statistically significantly lower in the hydrophobic group than in hydrophilic group C (P=.00) and hydrophilic group A (P=.000) at 3 years. There were no significant differences in the median EPCO area at 1 month; however, the area was statistically significantly less in the hydrophobic group than in hydrophilic group C and hydrophilic group A at 3 years (both P=.000). Four (12.9%) of 31 eyes in hydrophilic group C and 5 (16%) of 31 eyes in hydrophilic group A required an Nd:YAG capsulotomy; no eye in the hydrophobic group required a capsulotomy (P=.04 and P=.02, respectively). Conclusion Posterior Capsule opacification was significantly less with the Acrysof hydrophobic acrylic IOL at 3 years. Financial disclosure No author has a financial or proprietary interest in any material or method mentioned.

  • Posterior Capsule management in congenital cataract surgery
    Journal of Cataract and Refractive Surgery, 2011
    Co-Authors: Abhay R Vasavada, Viraj A. Vasavada, Sajani K Shah, Mamidipudi R Praveen, Mariejose Tassignon, Vaishali Vasavada, Jan Van Looveren, Ilse De Veuster, Rupal H Trivedi
    Abstract:

    Management of the Posterior Capsule significantly affects the outcome of pediatric cataract surgery. Posterior Capsule opacification (PCO) is rapid and virtually inevitable in very young children when adult-style cataract surgery is performed and the Posterior Capsule is left intact. In eyes with pediatric cataract, primary Posterior capsulotomy and vitrectomy are considered routine surgical steps, especially in younger children. The site of intraocular lens (IOL) fixation and the surgical technique used also affect the prevalence of PCO. The present systematic review evaluates the options available to prevent PCO or ensure a clear central visual axis after pediatric cataract surgery. Newer approaches to Posterior Capsule management such as pars plicata Posterior capsulorhexis, sutureless vitrectomy, sealed-Capsule irrigation, and bag-in-the-lens IOL are discussed. Management of the Posterior Capsule in the presence of a preexisting Posterior Capsule defect and Posterior Capsule plaque and options to treat PCO are also reviewed. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.

  • diagnosis of pre existing Posterior Capsule defect in traumatic white mature cataract with intact anterior Capsule
    Eye, 2006
    Co-Authors: Mayank A Nanavaty, Shetal M Raj, P A Mehta, Abhay R Vasavada
    Abstract:

    Diagnosis of pre-existing Posterior Capsule defect in traumatic white mature cataract with intact anterior Capsule

Rupal H Trivedi - One of the best experts on this subject based on the ideXlab platform.

  • Posterior Capsule opacification in pediatric eyes with and without traumatic cataract
    Journal of Cataract and Refractive Surgery, 2015
    Co-Authors: Rupal H Trivedi, Edward M Wilson
    Abstract:

    Purpose To compare the rate of visually significant Posterior Capsule opacification (PCO) in pediatric eyes with and without traumatic cataract. Setting Storm Eye Institute, Charleston, South Carolina, USA. Design Retrospective case control study. Methods Eyes operated on for traumatic cataract and having in-the-bag single-piece hydrophobic intraocular lens (IOL) implantation were identified. The control group of eyes operated on for nontraumatic cataract was matched with reference to age, management of the Posterior Capsule, type of IOL, and follow-up duration. Results Data from 58 eyes were studied. Age at surgery was comparable between the study group and the control group (7.3 versus 7.8 years) ( P = .7). The rate of PCO was statistically significantly different between the 2 groups (12/29 eyes versus 2/29 eyes) ( P = .002). This difference was more marked for those with intact Posterior Capsules (9/12 eyes [75%] and 1/12 eyes [8%] ( P = .001) compared with eyes with primary Posterior Capsulectomy and vitrectomy (3/17 [18%] and 1/17 [6%] ( P = .6). For eyes with intact Posterior Capsules, the duration between cataract surgery and intervention for PCO was 4 to 15 months in the traumatic cataract group; 1 eye in the nontraumatic cataract group required intervention 20 months after surgery. Conclusions Eyes with traumatic cataract were more likely to develop PCO than eyes without traumatic cataract. The results also suggest that PCO develops faster in eyes with traumatic cataract. Primary Posterior Capsulectomy and vitrectomy should be considered for children having traumatic cataract surgery, irrespective of age at the time of surgery. Financial Disclosure Neither author has a financial or proprietary interest in any material or method mentioned.

  • incidence and influence of Posterior Capsule striae on the development of Posterior Capsule opacification after 1 piece hydrophobic acrylic intraocular lens implantation
    Journal of Cataract and Refractive Surgery, 2012
    Co-Authors: Gauri D. Shah, Alpesh R. Shah, Abhay R Vasavada, M R Praveen, Rupal H Trivedi
    Abstract:

    Purpose To determine the incidence of intraoperative Posterior Capsule striae after implantation of a 1-piece hydrophobic acrylic intraocular lens (IOL), study the clinical impact on the patients’ vision, and assess whether the presence of Posterior Capsule striae increases the risk for Posterior Capsule opacification (PCO). Setting Iladevi Cataract & IOL Research Centre, Ahmedabad, India. Design Case-control study. Methods Part 1 of this study evaluated consecutive adult eyes having cataract surgery performed using standardized techniques with in-the-bag 1-piece hydrophobic acrylic IOL implantation. Posterior Capsule striae details were noted at the end of surgery. Part 2 was a case-control study comprising all patients with intraoperative striae and an age- and biometry-matched control group without striae, which was selected on a 1:1 ratio. Results Intraoperative Posterior Capsule striae were observed in 68 (13.6%) of 500 eyes. A single stria was seen in 43 eyes [63.2%], and multiple striae were seen in 25 eyes [36.7%]). There was no significant difference in logMAR corrected distance visual acuity at baseline ( P =.881) or at 3 years ( P =.191) between cases and controls. At 3 years, there was no statistically significant between-group difference in the median Evaluation of Posterior Capsule Opacification score or area values in the capsulorhexis margin ( P =.36 and P =.39, respectively) or in the central 3.0 mm optic area ( P =.40 and P =.42, respectively). Conclusion The incidence of Posterior Capsule striae was 13.6%. Intraoperative striae did not influence visual acuity or the development of PCO at the 3-year follow-up. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.

  • Posterior Capsule management in congenital cataract surgery
    Journal of Cataract and Refractive Surgery, 2011
    Co-Authors: Abhay R Vasavada, Viraj A. Vasavada, Sajani K Shah, Mamidipudi R Praveen, Mariejose Tassignon, Vaishali Vasavada, Jan Van Looveren, Ilse De Veuster, Rupal H Trivedi
    Abstract:

    Management of the Posterior Capsule significantly affects the outcome of pediatric cataract surgery. Posterior Capsule opacification (PCO) is rapid and virtually inevitable in very young children when adult-style cataract surgery is performed and the Posterior Capsule is left intact. In eyes with pediatric cataract, primary Posterior capsulotomy and vitrectomy are considered routine surgical steps, especially in younger children. The site of intraocular lens (IOL) fixation and the surgical technique used also affect the prevalence of PCO. The present systematic review evaluates the options available to prevent PCO or ensure a clear central visual axis after pediatric cataract surgery. Newer approaches to Posterior Capsule management such as pars plicata Posterior capsulorhexis, sutureless vitrectomy, sealed-Capsule irrigation, and bag-in-the-lens IOL are discussed. Management of the Posterior Capsule in the presence of a preexisting Posterior Capsule defect and Posterior Capsule plaque and options to treat PCO are also reviewed. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.

Viraj A. Vasavada - One of the best experts on this subject based on the ideXlab platform.

  • Comparison of Posterior Capsule opacification with hydrophobic acrylic and hydrophilic acrylic intraocular lenses
    Journal of Cataract and Refractive Surgery, 2011
    Co-Authors: Abhay R Vasavada, Alpesh R. Shah, Gauri D. Shah, Viraj A. Vasavada
    Abstract:

    Purpose To compare Posterior Capsule opacification (PCO) 3 years postoperatively in contralateral eyes with a single-piece hydrophobic acrylic and 1 of 2 single-piece hydrophilic acrylic intraocular lenses (IOLs) with different configurations. Setting Iladevi Cataract and IOL Research Institute, Ahmedabad, India. Design Prospective randomized clinical trial. Methods A hydrophobic Acrysof (hydrophobic group) or a hydrophilic C-flex (hydrophilic group C) or Akreos Adapt IOL (hydrophilic group A) was randomized for implantation in the fellow eye or vice versa of each patient. The Evaluation of Posterior Capsule Opacification (EPCO) area, EPCO score, and neodymium:YAG (Nd:YAG) capsulotomy rates were compared using digital photographs. Results The study enrolled 68 patients. Although there was no significant difference at 1 month, the median EPCO score was statistically significantly lower in the hydrophobic group than in hydrophilic group C (P=.00) and hydrophilic group A (P=.000) at 3 years. There were no significant differences in the median EPCO area at 1 month; however, the area was statistically significantly less in the hydrophobic group than in hydrophilic group C and hydrophilic group A at 3 years (both P=.000). Four (12.9%) of 31 eyes in hydrophilic group C and 5 (16%) of 31 eyes in hydrophilic group A required an Nd:YAG capsulotomy; no eye in the hydrophobic group required a capsulotomy (P=.04 and P=.02, respectively). Conclusion Posterior Capsule opacification was significantly less with the Acrysof hydrophobic acrylic IOL at 3 years. Financial disclosure No author has a financial or proprietary interest in any material or method mentioned.

  • Posterior Capsule management in congenital cataract surgery
    Journal of Cataract and Refractive Surgery, 2011
    Co-Authors: Abhay R Vasavada, Viraj A. Vasavada, Sajani K Shah, Mamidipudi R Praveen, Mariejose Tassignon, Vaishali Vasavada, Jan Van Looveren, Ilse De Veuster, Rupal H Trivedi
    Abstract:

    Management of the Posterior Capsule significantly affects the outcome of pediatric cataract surgery. Posterior Capsule opacification (PCO) is rapid and virtually inevitable in very young children when adult-style cataract surgery is performed and the Posterior Capsule is left intact. In eyes with pediatric cataract, primary Posterior capsulotomy and vitrectomy are considered routine surgical steps, especially in younger children. The site of intraocular lens (IOL) fixation and the surgical technique used also affect the prevalence of PCO. The present systematic review evaluates the options available to prevent PCO or ensure a clear central visual axis after pediatric cataract surgery. Newer approaches to Posterior Capsule management such as pars plicata Posterior capsulorhexis, sutureless vitrectomy, sealed-Capsule irrigation, and bag-in-the-lens IOL are discussed. Management of the Posterior Capsule in the presence of a preexisting Posterior Capsule defect and Posterior Capsule plaque and options to treat PCO are also reviewed. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.