The Experts below are selected from a list of 210 Experts worldwide ranked by ideXlab platform

Mustafa K Basskaya - One of the best experts on this subject based on the ideXlab platform.

  • microsurgical anatomy of the supracerebellar transtentorial approach to the Posterior mediobasal temporal region technical considerations with a case illustration
    Neurosurgery, 2008
    Co-Authors: Roham Moftakhar, Yusuf Izci, Mustafa K Basskaya
    Abstract:

    OBJECTIVE: Surgical access to the Posterior portion of the mediobasal temporal lobe presents a formidable challenge to neurosurgeons, and much controversy still exists regarding the selection of the surgical approach to this region. The supracerebellar transtentorial (SCTT) approach to the Posterior mediobasal temporal region can be used as an alternative to the subtemporal or transtemporal approaches. The aim of this study was to demonstrate the surgical anatomy of the SCTT approach and review the gyral, sulcal, and vascular anatomy of the Posterior mediobasal temporal lobe. The use of this approach in the resection of a ganglioglioma located in the left Posterior Parahippocampal Gyrus is illustrated. METHODS: The SCTT approach to the Posterior Parahippocampal Gyrus was performed on three silicone-injected cadaveric heads. The gyral, sulcal, and arterial anatomy of the Posterior mediobasal temporal lobe was studied in six formalin-fixed injected hemispheres. RESULTS: The SCTT approach provided a direct path to the Posterior mediobasal temporal lobe and exposed the Posterior Parahippocampal Gyrus as well as the adjacent gyri in all of the cadaveric specimens. Through this approach, gross total resection of the ganglioglioma was possible in out patient. CONCLUSION: The SCTT approach provided a viable surgical route to the Posterior mediobasal temporal lobe in the cadaveric studies. This approach provides an advantage over the subtemporal and transtemporal routes in that there is less temporal lobe retraction.

  • Microsurgical Anatomy of the Supracerebellar Transtentorial Approach to the Posterior Mediobasal Temporal Region: Technical Considerations With a Case Illustration
    Operative Neurosurgery, 2008
    Co-Authors: Roham Moftakhar, Yusuf Izci, Mustafa K Basskaya
    Abstract:

    Abstract Objective: Surgical access to the Posterior portion of the mediobasal temporal lobe presents a formidable challenge to neurosurgeons, and much controversy still exists regarding the selection of the surgical approach to this region. The supracerebellar transtentorial (SCTT) approach to the Posterior mediobasal temporal region can be used as an alternative to the subtemporal or transtemporal approaches. The aim of this study was to demonstrate the surgical anatomy of the SCTT approach and review the gyral, sulcal, and vascular anatomy of the Posterior mediobasal temporal lobe. The use of this approach in the resection of a ganglioglioma located in the left Posterior parahippocam-pal Gyrus is illustrated. Methods: The SCTT approach to the Posterior Parahippocampal Gyrus was performed on three silicone-injected cadaveric heads. The gyral, sulcal, and arterial anatomy of the Posterior mediobasal temporal lobe was studied in six formalin-fixed injected hemispheres. Results: The SCTT approach provided a direct path to the Posterior mediobasal temporal lobe and exposed the Posterior Parahippocampal Gyrus as well as the adjacent gyri in all of the cadaveric specimens. Through this approach, gross total resection of the ganglioglioma was possible in our patient. Conclusion: The SCTT approach provided a viable surgical route to the Posterior mediobasal temporal lobe in the cadaveric studies. This approach provides an advantage over the subtemporal and transtemporal routes in that there is less temporal lobe retraction.

Roham Moftakhar - One of the best experts on this subject based on the ideXlab platform.

  • microsurgical anatomy of the supracerebellar transtentorial approach to the Posterior mediobasal temporal region technical considerations with a case illustration
    Neurosurgery, 2008
    Co-Authors: Roham Moftakhar, Yusuf Izci, Mustafa K Basskaya
    Abstract:

    OBJECTIVE: Surgical access to the Posterior portion of the mediobasal temporal lobe presents a formidable challenge to neurosurgeons, and much controversy still exists regarding the selection of the surgical approach to this region. The supracerebellar transtentorial (SCTT) approach to the Posterior mediobasal temporal region can be used as an alternative to the subtemporal or transtemporal approaches. The aim of this study was to demonstrate the surgical anatomy of the SCTT approach and review the gyral, sulcal, and vascular anatomy of the Posterior mediobasal temporal lobe. The use of this approach in the resection of a ganglioglioma located in the left Posterior Parahippocampal Gyrus is illustrated. METHODS: The SCTT approach to the Posterior Parahippocampal Gyrus was performed on three silicone-injected cadaveric heads. The gyral, sulcal, and arterial anatomy of the Posterior mediobasal temporal lobe was studied in six formalin-fixed injected hemispheres. RESULTS: The SCTT approach provided a direct path to the Posterior mediobasal temporal lobe and exposed the Posterior Parahippocampal Gyrus as well as the adjacent gyri in all of the cadaveric specimens. Through this approach, gross total resection of the ganglioglioma was possible in out patient. CONCLUSION: The SCTT approach provided a viable surgical route to the Posterior mediobasal temporal lobe in the cadaveric studies. This approach provides an advantage over the subtemporal and transtemporal routes in that there is less temporal lobe retraction.

  • Microsurgical Anatomy of the Supracerebellar Transtentorial Approach to the Posterior Mediobasal Temporal Region: Technical Considerations With a Case Illustration
    Operative Neurosurgery, 2008
    Co-Authors: Roham Moftakhar, Yusuf Izci, Mustafa K Basskaya
    Abstract:

    Abstract Objective: Surgical access to the Posterior portion of the mediobasal temporal lobe presents a formidable challenge to neurosurgeons, and much controversy still exists regarding the selection of the surgical approach to this region. The supracerebellar transtentorial (SCTT) approach to the Posterior mediobasal temporal region can be used as an alternative to the subtemporal or transtemporal approaches. The aim of this study was to demonstrate the surgical anatomy of the SCTT approach and review the gyral, sulcal, and vascular anatomy of the Posterior mediobasal temporal lobe. The use of this approach in the resection of a ganglioglioma located in the left Posterior parahippocam-pal Gyrus is illustrated. Methods: The SCTT approach to the Posterior Parahippocampal Gyrus was performed on three silicone-injected cadaveric heads. The gyral, sulcal, and arterial anatomy of the Posterior mediobasal temporal lobe was studied in six formalin-fixed injected hemispheres. Results: The SCTT approach provided a direct path to the Posterior mediobasal temporal lobe and exposed the Posterior Parahippocampal Gyrus as well as the adjacent gyri in all of the cadaveric specimens. Through this approach, gross total resection of the ganglioglioma was possible in our patient. Conclusion: The SCTT approach provided a viable surgical route to the Posterior mediobasal temporal lobe in the cadaveric studies. This approach provides an advantage over the subtemporal and transtemporal routes in that there is less temporal lobe retraction.

Adam Zeman - One of the best experts on this subject based on the ideXlab platform.

  • the neural basis of autobiographical memory deficits in transient epileptic amnesia
    Neuropsychologia, 2012
    Co-Authors: Fraser Milton, Christopher Collett Butler, Abdelmalek Benattayallah, Adam Zeman
    Abstract:

    Transient epileptic amnesia (TEA) is a recently recognized form of temporal lobe epilepsy which is often associated with persistent interictal impairment of autobiographical memory. We used fMRI to investigate the neural basis of this deficit. Eleven patients with TEA, who had no significant deficits on standard tests of anterograde memory, and 17 age and IQ matched healthy controls retrieved memories from across the lifespan. Both groups engaged the autobiographical memory network, but activation in patients was less extensive than in controls. Direct comparison revealed hypoactivation of regions in the right hemisphere. Specifically, patients showed reduced activation of the Posterior Parahippocampal Gyrus (pPHG), especially for mid-life and recent memories, with decreased engagement of the right temporoparietal junction and the cerebellum. In addition, we found reduced effective connectivity in patients between the right pPHG and the right middle temporal Gyrus. Our results are consistent with other evidence that TEA is a syndrome of medial temporal lobe epilepsy and indicate that it affects the function and connectivity of regions within the autobiographical memory network.

  • MP 2 An fMRI study of autobiographical memory deficits in transient epileptic amnesia
    Journal of Neurology Neurosurgery and Psychiatry, 2012
    Co-Authors: Fraser Milton, Abdelmalek Benattayallah, C R Butler, Adam Zeman
    Abstract:

    Objective To identify the neural basis of autobiographical memory deficits in transient epileptic amnesia (TEA). Method 11 people (mean age: 65.91; SD=7.63) diagnosed with transient epileptic amnesia, all of whom complained of extensive autobiographical memory loss, and 17 age and IQ matched controls were recruited. Participants were matched on standard measures of anterograde memory. Participants recalled 32 previously identified autobiographical memories, specific in time and place, from four different time periods (childhood, young adult, middle aged and recent), during fMRI scanning. Activations were analysed using SPM8 software, effective connectivity using dynamic causal modelling (DCM). Post-scan ratings of the subjective vividness, level of detail, pleasantness, personal significance and frequency of retrieval of the memories were recorded. Results Both patients and controls activated core regions of the autobiographical memory network. However, patients had reduced activation in the right Posterior Parahippocampal Gyrus (pPHG), particularly for more recent memories, together with decreased engagement of the right temporoparietal junction and the right cerebellum. In addition, we found reduced effective connectivity in patients between the right pPHG and the right middle temporal Gyrus. There were no differences in the subjective ratings of memories between patients and control participants. Conclusion The reduction of activity in the right pPHG is consistent with other evidence that TEA is a disorder of the medial temporal lobes (MTL) and further implicates the pPHG as a key region for contextual information. These MTL differences were most marked for recent and mid-life periods suggesting that, at least at the neural level, remote memories are more robust than recent memories. We also found reduced effective connectivity in patients between the right pPHG and the right middle temporal Gyrus. This may reflect persisting effects of the seizures, the continued presence of sub-clinical epileptiform activity or the sequelae of subtle structural changes in the MTL in our patient group.

  • An fMRI study of long-term everyday memory using SenseCam
    Memory, 2011
    Co-Authors: Fraser Milton, Nils Muhlert, Christopher Collett Butler, Abdelmalek Benattayallah, Alicia Smith, Adam Zeman
    Abstract:

    We used a novel automatic camera, SenseCam, to investigate recognition memory for real-life events at a 5-month retention interval. Using fMRI we assessed recollection and familiarity memory using the remember/know procedure. Recollection evoked no medial temporal lobe (MTL) activation compared to familiarity and new responses. Instead, recollection activated diverse regions in neocortex including medial prefrontal cortex. We observed decreased activation in anterior hippocampus/ anterior Parahippocampal Gyrus (aPHG) at 5 months compared to a 36-hour retention interval. Familiarity was associated with greater activation in aPHG and Posterior Parahippocampal Gyrus (pPHG) than recollection and new responses. Familiarity activation decreased over time in anterior hippocampus/aPHG and Posterior hippocampus/pPHG. The engagement of neocortical regions such as medial prefrontal cortex at a 5-month delay, together with the reduced MTL activation at 5 months relative to at 36 hours is in line with the assumptions of Consolidation theory. SenseCam provides a valuable technique for assessing the processes that underlie remote everyday recognition memory.

  • The neural correlates of everyday recognition memory.
    Brain and Cognition, 2011
    Co-Authors: Fraser Milton, Nils Muhlert, Christopher Collett Butler, Abdelmalek Benattayallah, Adam Zeman
    Abstract:

    We used a novel automatic camera, SenseCam, to create a recognition memory test for real-life events. Adapting a ‘Remember/Know’ paradigm, we asked healthy undergraduates, who wore SenseCam for 2 days, in their everyday environments, to classify images as strongly or weakly remembered, strongly or weakly familiar or novel, while brain activation was recorded with functional MRI. Overlapping, widely distributed sets of brain regions were activated by recollected and familiar stimuli. Within the medial temporal lobes, ‘Remember’ responses specifically elicited greater activity in the right anterior and Posterior Parahippocampal Gyrus than ‘Know’ responses. ‘New’ responses activated anterior Parahippocampal regions. A parametric analysis, across correctly recognised items, revealed increasing activation in the right hippocampus and Posterior Parahippocampal Gyrus (pPHG). This may reflect modulation of these regions by the degree of recollection or, alternatively, by increasing memory strength. Strong recollection elicited greater activity in the left Posterior hippocampus/pPHG than weak recollection indicating that this region is specifically modulated by the degree of recollection.

Alain Berthoz - One of the best experts on this subject based on the ideXlab platform.

  • timing of Posterior Parahippocampal Gyrus activity reveals multiple scene processing stages
    Human Brain Mapping, 2013
    Co-Authors: Julien Bastin, Giorgia Committeri, Philippe Kahane, Gaspare Galati, Lorella Minotti, Jean-philippe Lachaux, Alain Berthoz
    Abstract:

    Posterior Parahippocampal Gyrus (PPHG) is strongly involved during scene recognition and spatial cognition. How PPHG electrophysiological activity could underlie these functions, and whether they share similar timing mechanisms is unknown. We addressed this question in two intracerebral experiments which revealed that PPHG neural activity dissociated an early stimulus-driven effect (>200 and 600 and <800 ms). Strongest PPHG gamma band (50-150 Hz) activities were found early when subjects passively viewed scenes (scene selectivity effect) and lately when they had to estimate the position of an object relative to the environment (allocentric effect). Based on single trial analyses, we were able to predict when patients viewed scenes (compared to other visual categories) and when they performed allocentric judgments (compared to other spatial judgments). The anatomical location corresponding to the strongest effects was in the depth of the col- lateral sulcus. Our findings directly affect current theories of visual scene processing and spatial orien- tation by providing new timing constraints and by demonstrating the existence of separable information processing stages in the functionally defined Parahippocampal place area. Hum Brain

  • Timing of Posterior Parahippocampal Gyrus activity reveals multiple scene processing stages.
    Human Brain Mapping, 2012
    Co-Authors: Julien Bastin, Giorgia Committeri, Philippe Kahane, Gaspare Galati, Lorella Minotti, Jean-philippe Lachaux, Alain Berthoz
    Abstract:

    Posterior Parahippocampal Gyrus (PPHG) is strongly involved during scene recognition and spatial cognition. How PPHG electrophysiological activity could underlie these functions, and whether they share similar timing mechanisms is unknown. We addressed this question in two intracerebral experiments which revealed that PPHG neural activity dissociated an early stimulus-driven effect (>200 and 600 and

Yusuf Izci - One of the best experts on this subject based on the ideXlab platform.

  • microsurgical anatomy of the supracerebellar transtentorial approach to the Posterior mediobasal temporal region technical considerations with a case illustration
    Neurosurgery, 2008
    Co-Authors: Roham Moftakhar, Yusuf Izci, Mustafa K Basskaya
    Abstract:

    OBJECTIVE: Surgical access to the Posterior portion of the mediobasal temporal lobe presents a formidable challenge to neurosurgeons, and much controversy still exists regarding the selection of the surgical approach to this region. The supracerebellar transtentorial (SCTT) approach to the Posterior mediobasal temporal region can be used as an alternative to the subtemporal or transtemporal approaches. The aim of this study was to demonstrate the surgical anatomy of the SCTT approach and review the gyral, sulcal, and vascular anatomy of the Posterior mediobasal temporal lobe. The use of this approach in the resection of a ganglioglioma located in the left Posterior Parahippocampal Gyrus is illustrated. METHODS: The SCTT approach to the Posterior Parahippocampal Gyrus was performed on three silicone-injected cadaveric heads. The gyral, sulcal, and arterial anatomy of the Posterior mediobasal temporal lobe was studied in six formalin-fixed injected hemispheres. RESULTS: The SCTT approach provided a direct path to the Posterior mediobasal temporal lobe and exposed the Posterior Parahippocampal Gyrus as well as the adjacent gyri in all of the cadaveric specimens. Through this approach, gross total resection of the ganglioglioma was possible in out patient. CONCLUSION: The SCTT approach provided a viable surgical route to the Posterior mediobasal temporal lobe in the cadaveric studies. This approach provides an advantage over the subtemporal and transtemporal routes in that there is less temporal lobe retraction.

  • Microsurgical Anatomy of the Supracerebellar Transtentorial Approach to the Posterior Mediobasal Temporal Region: Technical Considerations With a Case Illustration
    Operative Neurosurgery, 2008
    Co-Authors: Roham Moftakhar, Yusuf Izci, Mustafa K Basskaya
    Abstract:

    Abstract Objective: Surgical access to the Posterior portion of the mediobasal temporal lobe presents a formidable challenge to neurosurgeons, and much controversy still exists regarding the selection of the surgical approach to this region. The supracerebellar transtentorial (SCTT) approach to the Posterior mediobasal temporal region can be used as an alternative to the subtemporal or transtemporal approaches. The aim of this study was to demonstrate the surgical anatomy of the SCTT approach and review the gyral, sulcal, and vascular anatomy of the Posterior mediobasal temporal lobe. The use of this approach in the resection of a ganglioglioma located in the left Posterior parahippocam-pal Gyrus is illustrated. Methods: The SCTT approach to the Posterior Parahippocampal Gyrus was performed on three silicone-injected cadaveric heads. The gyral, sulcal, and arterial anatomy of the Posterior mediobasal temporal lobe was studied in six formalin-fixed injected hemispheres. Results: The SCTT approach provided a direct path to the Posterior mediobasal temporal lobe and exposed the Posterior Parahippocampal Gyrus as well as the adjacent gyri in all of the cadaveric specimens. Through this approach, gross total resection of the ganglioglioma was possible in our patient. Conclusion: The SCTT approach provided a viable surgical route to the Posterior mediobasal temporal lobe in the cadaveric studies. This approach provides an advantage over the subtemporal and transtemporal routes in that there is less temporal lobe retraction.