The Experts below are selected from a list of 831 Experts worldwide ranked by ideXlab platform
Scott A Laney - One of the best experts on this subject based on the ideXlab platform.
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patterns of Progressive Massive Fibrosis on modern coal miner chest radiographs
Archives of Environmental & Occupational Health, 2020Co-Authors: Cara N Halldin, David J Blackley, Travis Markle, Robert A Cohen, Scott A LaneyAbstract:Clinical teaching generally asserts that large opacities of Progressive Massive Fibrosis (PMF) on chest radiographs present primarily bilaterally in the upper lung zones, and with an elevated backg...
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Progressive Massive Fibrosis resurgence identified in u s coal miners filing for black lung benefits 1970 2016
Annals of the American Thoracic Society, 2018Co-Authors: David J Blackley, Cara N Halldin, Eileen Storey, Scott A Laney, Robert A Cohen, Kirsten S Almberg, Cecile S RoseAbstract:Rationale: There has been a resurgence of Progressive Massive Fibrosis (PMF) in the United States, particularly among central Appalachian miners.Objectives: We characterized the proportion of PMF a...
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work practices and respiratory health status of appalachian coal miners with Progressive Massive Fibrosis
Journal of Occupational and Environmental Medicine, 2018Co-Authors: Laura E Reynolds, David J Blackley, Eileen Storey, Scott A Laney, Jay F Colinet, Drew J Potts, Connie Short, Ron Carson, Kathleen A Clark, Cara N HalldinAbstract:OBJECTIVE The aim of this study was to characterize workplace practices and respiratory health among coal miners with large opacities consistent with Progressive Massive Fibrosis (PMF) who received care at a federally funded black lung clinic network in Virginia. METHODS Participants were interviewed about their workplace practices and respiratory health. Medical records were reviewed. RESULTS Nineteen former coal miners were included. Miners reported cutting rock, working downwind of dust-generating equipment, nonadherence to mine ventilation plans (including dust controls), improper sampling of respirable coal mine dust exposures, working after developing respiratory illness, and suffering from debilitating respiratory symptoms. CONCLUSION Consistent themes of suboptimal workplace practices contributing to development of PMF emerged during the interviews. Some of the practices reported were unsafe and unacceptable. Further research is needed to determine the prevalence of these factors and how best to address them.
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Progressive Massive Fibrosis in coal miners from 3 clinics in virginia
JAMA, 2018Co-Authors: David J Blackley, Cara N Halldin, Eileen Storey, Laura E Reynolds, Connie Short, Ron Carson, Scott A LaneyAbstract:This study describes the demographic and radiographic characteristics of 416 coal miners with Progressive Massive pulmonary Fibrosis (PMF) identified by pneumoconiosis screening as part of the US Coal Workers’ Health Surveillance Program.
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radiographic disease progression in contemporary us coal miners with Progressive Massive Fibrosis
Occupational and Environmental Medicine, 2017Co-Authors: Scott A Laney, David J Blackley, Cara N HalldinAbstract:Introduction Among contemporary US coal miners, there has been an increase in the prevalence and severity of pneumoconiosis, including its advanced form Progressive Massive Fibrosis (PMF). We examine radiographic progression in Coal Workers’ Health Surveillance Program (CWHSP) participants. Methods CWHSP participants with a final determination of PMF during 1 January 2000–1 October 2016 with at least one prior radiograph in the system were included. We characterised demographics, participation and progression patterns. Results A total of 192 miners with a PMF determination contributed at least one additional radiograph (total count: 2–10). Mean age at first radiograph was 28.8 years, 162 (84%) worked in Kentucky, Virginia or West Virginia and 169 (88%) worked exclusively underground. A total of 163 (85%) miners had a normal initial radiograph. Mean time from most recent normal radiograph to one with a PMF determination was 20.7 years (range: 1–43) and 27 (17%) progressed to PMF in less than 10 years. Discussion Dust exposure is the sole cause of this disease, and a substantial number of these miners progressed from normal to PMF in less than a decade. Participation in CWHSP is voluntary, and these findings are influenced by participation patterns, so for many miners it remains unclear how rapidly their disease progressed. The National Institute for Occupational Safety and Health recommends all working miners to participate in radiographic surveillance at 5-year intervals. Improved participation could allow more precise characterisation of the burden and characteristics of pneumoconiosis in US coal miners and provide an important early detection tool to prevent cases of severe disease.
Robert A Cohen - One of the best experts on this subject based on the ideXlab platform.
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patterns of Progressive Massive Fibrosis on modern coal miner chest radiographs
Archives of Environmental & Occupational Health, 2020Co-Authors: Cara N Halldin, David J Blackley, Travis Markle, Robert A Cohen, Scott A LaneyAbstract:Clinical teaching generally asserts that large opacities of Progressive Massive Fibrosis (PMF) on chest radiographs present primarily bilaterally in the upper lung zones, and with an elevated backg...
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Progressive Massive Fibrosis resurgence identified in u s coal miners filing for black lung benefits 1970 2016
Annals of the American Thoracic Society, 2018Co-Authors: David J Blackley, Cara N Halldin, Eileen Storey, Scott A Laney, Robert A Cohen, Kirsten S Almberg, Cecile S RoseAbstract:Rationale: There has been a resurgence of Progressive Massive Fibrosis (PMF) in the United States, particularly among central Appalachian miners.Objectives: We characterized the proportion of PMF a...
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lung pathology in u s coal workers with rapidly Progressive pneumoconiosis implicates silica and silicates
American Journal of Respiratory and Critical Care Medicine, 2016Co-Authors: Robert A Cohen, Cecile S Rose, Edward L Petsonk, Andrew Churg, Byron Young, Jerrold L Abraham, Michael Regier, Asif Najmuddin, Francis H Y GreenAbstract:Rationale: Recent reports of Progressive Massive Fibrosis and rapidly Progressive pneumoconiosis in U.S. coal miners have raised concerns about excessive exposures to coal mine dust, despite reports of declining dust levels.Objectives: To evaluate the histologic abnormalities and retained dust particles in available coal miner lung pathology specimens, and to compare these findings with those derived from corresponding chest radiographs.Methods: Miners with severe disease and available lung tissue were identified through investigator outreach. Demographic as well as smoking and work history information was obtained. Chest radiographs were interpreted according to the International Labor Organization classification scheme to determine if criteria for rapidly Progressive pneumoconiosis were confirmed. Pathology slides were scored by three expert pulmonary pathologists using a standardized nomenclature and scoring system.Measurements and Main Results: Thirteen cases were reviewed, many of which had features ...
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lung disease caused by exposure to coal mine and silica dust
Seminars in Respiratory and Critical Care Medicine, 2008Co-Authors: Robert A Cohen, Aiyub Patel, Francis H Y GreenAbstract:Susceptible workers exposed to coal mine and silica dust may develop a variety of pulmonary diseases. The prime example is classical pneumoconiosis, a nodular interstitial lung disease that, in severe cases, may lead to Progressive Massive Fibrosis (PMF) . Exposure to silica and coal mine dusts may also result in pulmonary scarring in a pattern that mimics idiopathic pulmonary Fibrosis, and in chronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis, that appears indistinguishable from obstructive lung disease caused by exposure to tobacco smoke. Coal mine and silica dust may therefore result in restrictive, obstructive, or mixed patterns of impairment on pulmonary function testing. Most physicians are aware of the nodular fibrosing pulmonary tissue reactions in response to retained dust, but they may not realize that these other reactions of the pulmonary parenchyma and airways to dust exist and can result in significant respiratory dysfunction in sensitive individuals. This article discusses current data on exposure to coal mine and silica dust in the United States, the epidemiology of the diseases caused by these exposures, and new concepts of causation and pathogenesis. We also review the patterns of pulmonary disease and impairment that may result.
Cara N Halldin - One of the best experts on this subject based on the ideXlab platform.
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patterns of Progressive Massive Fibrosis on modern coal miner chest radiographs
Archives of Environmental & Occupational Health, 2020Co-Authors: Cara N Halldin, David J Blackley, Travis Markle, Robert A Cohen, Scott A LaneyAbstract:Clinical teaching generally asserts that large opacities of Progressive Massive Fibrosis (PMF) on chest radiographs present primarily bilaterally in the upper lung zones, and with an elevated backg...
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Progressive Massive Fibrosis resurgence identified in u s coal miners filing for black lung benefits 1970 2016
Annals of the American Thoracic Society, 2018Co-Authors: David J Blackley, Cara N Halldin, Eileen Storey, Scott A Laney, Robert A Cohen, Kirsten S Almberg, Cecile S RoseAbstract:Rationale: There has been a resurgence of Progressive Massive Fibrosis (PMF) in the United States, particularly among central Appalachian miners.Objectives: We characterized the proportion of PMF a...
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work practices and respiratory health status of appalachian coal miners with Progressive Massive Fibrosis
Journal of Occupational and Environmental Medicine, 2018Co-Authors: Laura E Reynolds, David J Blackley, Eileen Storey, Scott A Laney, Jay F Colinet, Drew J Potts, Connie Short, Ron Carson, Kathleen A Clark, Cara N HalldinAbstract:OBJECTIVE The aim of this study was to characterize workplace practices and respiratory health among coal miners with large opacities consistent with Progressive Massive Fibrosis (PMF) who received care at a federally funded black lung clinic network in Virginia. METHODS Participants were interviewed about their workplace practices and respiratory health. Medical records were reviewed. RESULTS Nineteen former coal miners were included. Miners reported cutting rock, working downwind of dust-generating equipment, nonadherence to mine ventilation plans (including dust controls), improper sampling of respirable coal mine dust exposures, working after developing respiratory illness, and suffering from debilitating respiratory symptoms. CONCLUSION Consistent themes of suboptimal workplace practices contributing to development of PMF emerged during the interviews. Some of the practices reported were unsafe and unacceptable. Further research is needed to determine the prevalence of these factors and how best to address them.
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Progressive Massive Fibrosis in coal miners from 3 clinics in virginia
JAMA, 2018Co-Authors: David J Blackley, Cara N Halldin, Eileen Storey, Laura E Reynolds, Connie Short, Ron Carson, Scott A LaneyAbstract:This study describes the demographic and radiographic characteristics of 416 coal miners with Progressive Massive pulmonary Fibrosis (PMF) identified by pneumoconiosis screening as part of the US Coal Workers’ Health Surveillance Program.
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radiographic disease progression in contemporary us coal miners with Progressive Massive Fibrosis
Occupational and Environmental Medicine, 2017Co-Authors: Scott A Laney, David J Blackley, Cara N HalldinAbstract:Introduction Among contemporary US coal miners, there has been an increase in the prevalence and severity of pneumoconiosis, including its advanced form Progressive Massive Fibrosis (PMF). We examine radiographic progression in Coal Workers’ Health Surveillance Program (CWHSP) participants. Methods CWHSP participants with a final determination of PMF during 1 January 2000–1 October 2016 with at least one prior radiograph in the system were included. We characterised demographics, participation and progression patterns. Results A total of 192 miners with a PMF determination contributed at least one additional radiograph (total count: 2–10). Mean age at first radiograph was 28.8 years, 162 (84%) worked in Kentucky, Virginia or West Virginia and 169 (88%) worked exclusively underground. A total of 163 (85%) miners had a normal initial radiograph. Mean time from most recent normal radiograph to one with a PMF determination was 20.7 years (range: 1–43) and 27 (17%) progressed to PMF in less than 10 years. Discussion Dust exposure is the sole cause of this disease, and a substantial number of these miners progressed from normal to PMF in less than a decade. Participation in CWHSP is voluntary, and these findings are influenced by participation patterns, so for many miners it remains unclear how rapidly their disease progressed. The National Institute for Occupational Safety and Health recommends all working miners to participate in radiographic surveillance at 5-year intervals. Improved participation could allow more precise characterisation of the burden and characteristics of pneumoconiosis in US coal miners and provide an important early detection tool to prevent cases of severe disease.
Michael D Attfield - One of the best experts on this subject based on the ideXlab platform.
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potential determinants of coal workers pneumoconiosis advanced pneumoconiosis and Progressive Massive Fibrosis among underground coal miners in the united states 2005 2009
American Journal of Public Health, 2012Co-Authors: Scott A Laney, Edward L Petsonk, Janet M Hale, Anita L Wolfe, Michael D AttfieldAbstract:Objectives. We better defined the distribution and determinants of coal workers’ pneumoconiosis (CWP) among US underground coal miners.Methods. We obtained chest radiographs from the mobile unit of an enhanced surveillance program begun in 2005 by the National Institute for Occupational Safety and Health for underground coal miners. B Readers classified them for presence of pneumoconiosis.Results. Miners from 15 states participated (n = 6658). The prevalence of CWP was higher in 3 states (Kentucky, 9.0%; Virginia, 8.0%; West Virginia, 4.8%) than in 12 other states (age-adjusted risk ratio [RR] = 4.5; 95% confidence interval [CI] = 3.3, 6.1). Miners in these 3 states were younger and had less mining tenure, but advanced CWP (category ≥ 2/1; RR = 8.1; 95% CI = 3.9, 16.9) and Progressive Massive Fibrosis (RR = 10.5; 95% CI = 3.8, 29.1) was more prevalent among them. Advanced CWP and Progressive Massive Fibrosis were more prevalent among workers at mines with fewer than 155 miners, irrespective of mining regi...
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does selection bias explain increases in pneumoconiosis observed in united states coal miners
European Respiratory Journal, 2011Co-Authors: Edward L Petsonk, Janet M Hale, Eva Suarthana, A S Laney, Anita Wolfe, Nicole T Edwards, Michael D AttfieldAbstract:Background: Radiographic surveillance among U.S. coal miners showed declining tenure-specific disease prevalence until 2000, when abnormalities consistent with coal workers9 pneumoconiosis (CWP) and Progressive Massive Fibrosis (PMF) began to increase. Some have suggested the increase may be due to selection bias in the surveillance programs. Methods: For the period 2006-2009, results from the routine health surveillance program (in which costs of radiographs are paid by industry) were compared with results of a government-funded enhanced surveillance program utilizing a mobile examination unit stationed in mining regions. Observed disease prevalence was stratified by region and by mining tenure, and compared between participants in the two programs. Results: Overall, participants in the routine and enhanced surveillance programs were similar for participation rate, mining location (surface/underground), gender, and race/ethnicity. Participants in the enhanced program were older (47.1 vs 36.4 yr), had longer tenure (21.8 vs 11.4 yr), and higher prevalence of abnormal radiographs (3.9% vs 1.9%) compared to the routine program. However, among miners with at least 20 years of mining, rates of both CWP (6.1% vs 7.0%) and PMF (1.1% vs 0.9%) were similar for participants in the enhanced and routine surveillance programs, respectively. Conclusions: Tenure-specific prevalences in the routine and enhanced surveillance programs were similar, indicating that selection bias does not explain the recent increases in CWP and PMF among U.S. miners. Previous reports have implicated increased lung deposition of respirable dust and silica as explanations for the ongoing pneumoconiosis problem.
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coal workers pneumoconiosis and Progressive Massive Fibrosis are increasingly more prevalent among workers in small underground coal mines in the united states
Occupational and Environmental Medicine, 2010Co-Authors: Scott A Laney, Michael D AttfieldAbstract:Objective To determine whether the prevalence of coal workers’ pneumoconiosis (CWP) or Progressive Massive Fibrosis (PMF) among United States underground miners is associated with mine size. Methods We examined chest radiographs from 1970 to 2009 of working miners who participated in the National Coal Workers Health Surveillance Program for the presence of small and large opacities consistent with pneumoconiosis, based upon the International Labour Organization classification system. Results A total of 145512 miners contributed 240067 radiographs for analysis. From the 1990s to the 2000s, the prevalence of radiographic CWP increased among miners in mines of all sizes, while miners working in mines with fewer than 50 employees had a significantly higher prevalence of CWP compared to miners who worked in mines with 50 or more employees (p<0.0001). When adjusted for age and within-miner correlation, the difference in prevalence of CWP by mine size was significant for all decades. Since 1999, miners from small mines were five times more likely to have radiographic evidence of PMF (1.0% of miners) compared to miners from larger mines (0.2% of miners) with a prevalence ratio of 5.0 and 95% CI 3.3 to 7.5. Conclusion The prevalence of CWP among United States coal miners is increasing in mines of all sizes, while CWP and PMF are much more prevalent among workers from underground mines with fewer than 50 workers.
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risks of occupational respiratory diseases among u s coal miners
Applied Occupational and Environmental Hygiene, 1997Co-Authors: Eileen D Kuempel, Michael D Attfield, Randall J Smith, Leslie T StaynerAbstract:Abstract The excess (exposure-attributable) risks of certain respiratory diseases and outcomes were estimated for U.S. coal miners exposed to respirable coal mine dust for various durations and concentrations, including a 45-year working lifetime at the current 2-mg/m3 standard. Multiple linear and logistic regression models were used to compute predicted prevalence and excess risk of disease, using data and regression results from published epidemiological studies of U.S. coal miners. Disease outcomes evaluated include simple coal workers' pneumoconiosis, Progressive Massive Fibrosis, and clinically significant deficits in lung function, measured as forced expiratory volume in 1 second of < 80% or < 65% of predicted normal values. Point estimates of excess risk of Progressive Massive Fibrosis ranged from 1/1000 to 167/1000 among coal miners exposed to respirable coal mine dust at a mean concentration of 2 mg/m3 for 45 years. This range reflects coal rank and study differences. Point estimates for an exce...
David Shitrit - One of the best experts on this subject based on the ideXlab platform.
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artificial stone silicosis disease resurgence among artificial stone workers
Chest, 2012Co-Authors: Mordechai R. Kramer, Elizabeth Fireman, Paul D Blanc, Anat Amital, Alexander Guber, Nader Abdul Rhahman, David ShitritAbstract:Background Silicosis is a Progressive, fibrotic, occupational lung disease resulting from inhalation of respirable crystalline silica. This disease is preventable through appropriate workplace practices. We systematically assessed an outbreak of silicosis among patients referred to our center for lung transplant. Methods This retrospective cohort analysis included all patients with a diagnosis of silicosis who were referred for evaluation to the National Lung Transplantation Program in Israel from January 1997 through December 2010. We also compared the incidence of lung transplantation (LTX) due to silicosis in Israel with that of the International Society for Heart and Lung Transplantation (ISHLT) registry. Results During the 14-year study period, 25 patients with silicosis were referred for evaluation, including 10 patients who went on to undergo LTX. All patients were exposed by dry cutting a relatively new, artificial, decorative stone product with high crystalline silica content used primarily for kitchen countertops and bathroom fixtures. The patients had moderate-to-severe restrictive lung disease. Two patients developed Progressive Massive Fibrosis; none manifested acute silicosis (silicoproteinosis). Three patients died during follow-up, without LTX. Based on the ISHLT registry incidence, 0.68 silicosis cases would have been expected instead of the 10 observed (incidence ratio, 14.6; 95% CI, 7.02-26.8). Conclusions This silicosis outbreak is important because of the worldwide use of this and similar high-silica-content, artificial stone products. Further cases are likely to occur unless effective preventive measures are undertaken and existing safety practices are enforced.
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artificial stone silicosis corrected disease resurgence among artificial stone workers
Chest, 2012Co-Authors: Mordechai R. Kramer, Elizabeth Fireman, Paul D Blanc, Anat Amital, Alexander Guber, Nader Abdul Rhahman, David ShitritAbstract:Background Silicosis is a Progressive, fibrotic, occupational lung disease resulting from inhalation of respirable crystalline silica. This disease is preventable through appropriate workplace practices. We systematically assessed an outbreak of silicosis among patients referred to our center for lung transplant. Methods This retrospective cohort analysis included all patients with a diagnosis of silicosis who were referred for evaluation to the National Lung Transplantation Program in Israel from January 1997 through December 2010. We also compared the incidence of lung transplantation (LTX) due to silicosis in Israel with that of the International Society for Heart and Lung Transplantation (ISHLT) registry. Results During the 14-year study period, 25 patients with silicosis were referred for evaluation, including 10 patients who went on to undergo LTX. All patients were exposed by dry cutting a relatively new, artificial, decorative stone product with high crystalline silica content used primarily for kitchen countertops and bathroom fixtures. The patients had moderate-to-severe restrictive lung disease. Two patients developed Progressive Massive Fibrosis; none manifested acute silicosis (silicoproteinosis). Three patients died during follow-up, without LTX. Based on the ISHLT registry incidence, 0.68 silicosis cases would have been expected instead of the 10 observed (incidence ratio, 14.6; 95% CI, 7.02-26.8). Conclusions This silicosis outbreak is important because of the worldwide use of this and similar high-silica-content, artificial stone products. Further cases are likely to occur unless effective preventive measures are undertaken and existing safety practices are enforced.
