The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform
Deng Shi - One of the best experts on this subject based on the ideXlab platform.
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The general pharmacological effects of zedoary turmeric Oil Gelatin Microspheres via Hepatic Artery
The Chinese Journal of Modern Applied Pharmacy, 2003Co-Authors: Deng ShiAbstract:OBJECTIVE The effect of Zedoary Turmeric Oil Gelatin Microspheres(ZT GMS) on rat's nervous system as well as canine respiration and cardiovascular systems were observed, and it's safety for intervention therapy was probed. METHOD To consider the effect of ZT GMS to rats' psyche nerve system by stomach duodenum Artery cannula to Proper Hepatic Artery modelling interventional therapy. Rats' general behavior and ability to walk a 90 cm long×2.5 cm wide wood beam were observed after ZT GMS administered through Proper Hepatic Artery. The effect of ZT GMS to respiratory system and cardiovascular system were recorded by six channel physiological recorder after ZT GMS administered from femoral Artery to Proper Hepatic Artery under x rays and arterial contrast.RESULTS ZT GMS doesn't affect rat's general behavior, posture, gait and pupil. There is no salivation and muscular tremor in rats. In the test of ability to walk the wood beam, the falling of times is less than three times every 3 minutes. Also, ZT GMS doesn't affect respiratory frequency, blood pressure and heart rates of dogs.CONCLUSION The study indicated that intervention therapy of ZT GMS from Hepatic Artery has no obvious effects on respiratory, cardiovascular, and nervous systems. It exerts only local action, while the systemic side effect is little.
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Experimental Study of the Acute Toxicity of the Zedoary Turmeric Oil Gelatin Microsphere
Herald of Medicine, 2002Co-Authors: Deng ShiAbstract:Objective:In order to observe the safety of a special preparation form zedoary turmeric oil gelatin microspheres (ZT GMS) for interventional therapy, we studied the acute toxicity of ZT GMS. Methods:ZT MGS was administered through the Proper Hepatic Artery, the manifestations of acute toxicity was observed for 14 days, the biochemical indices of blood tested, and the LD 50 calculated with Bliss method. Results:The LD 50 of ZT GMS administered via Proper Hepatic Artery was 17.19 mg·kg 1 , the GPT?GOT?T BiL?D BiL?BCr and BUN of the dead animals were significantly increased, while changes of the biochemical indices in the survived animals were not significant. The results of the histopathological examination suggested the possibility of dystopic embolism occurrence in animals administered with ZT GMS. Conclusion:The study indicated that the acute toxicity of ZT GMS might result from the dystopic embolism rather than the oil of zedoary turmeric itself entrapped in ZT GMS.
Yoshito Takeuchi - One of the best experts on this subject based on the ideXlab platform.
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extraHepatic arterial supply to the liver observation with a unified ct and angiography system during temporary balloon occlusion of the Proper Hepatic Artery
Radiology, 1998Co-Authors: Yoshito Takeuchi, Yasuaki Arai, Y Inaba, K Ohno, T Maeda, Y ItaiAbstract:PURPOSE: To evaluate routes of potential extraHepatic arterial supply to the liver. MATERIALS AND METHODS: Twenty-three patients with liver tumors underwent computed tomographic (CT) arteriography of extraHepatic arteries before and after temporary balloon occlusion of the Proper Hepatic Artery. The right inferior phrenic Artery (RIPA), left inferior phrenic Artery (LIPA), superior mesenteric Artery (SMA), celiac axis, and left gastric Artery (LGA) were evaluated. RESULTS: During temporary balloon occlusion of the Proper Hepatic Artery, extraHepatic arterial supply was immediately evident in 22 of 23 patients (96%). The liver was supplied by the RIPA in 17 of 20 patients (85%), by the LIPA in five of six (83%), by the SMA in eight of 16 (50%), by the celiac axis in two of 10 (20%), and by the LGA in one of six (17%). There was no apparent relationship between the enhanced zones supplied by extraHepatic arteries and the presence or absence of nearby tumors. CONCLUSION: ExtraHepatic arterial supply to the l...
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Arterial redistribution of extraHepatic collaterals to the liver under temporary balloon occlusion of the Proper Hepatic Artery
Nihon Igaku Hōshasen Gakkai zasshi. Nippon acta radiologica, 1998Co-Authors: Yoshito Takeuchi, Yasuaki Arai, K Ohno, Inaba Y, Maeda T, Itai YAbstract:: Three patients with liver metastases receiving transarterial chemotherapy underwent embolization of extraHepatic collaterals to the liver under temporary balloon occlusion of the Proper Hepatic Artery. Enhancement in the liver and tumors was observed at CT arteriography through the right inferior phrenic Artery and was accentuated under balloon occlusion in all patients. A Cyanoacrylate-Lipiodol mixture was infused through the right inferior phrenic Artery to occlude arterial communications with intraHepatic arteries. Better contrast agent distribution was obtained in all patients after embolization. It is suggested that this procedure can be effective for arterial redistribution against extraHepatic collaterals to the liver.
Carlo Bartolozzi - One of the best experts on this subject based on the ideXlab platform.
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Image Fusion of Preprocedural CTA with Real-time Fluoroscopy to Guide Proper Hepatic Artery Catheterization During Transarterial Chemoembolization of Hepatocellular Carcinoma: A Feasibility Study
Cardiovascular and interventional radiology, 2012Co-Authors: Irene Bargellini, F Turini, Elena Bozzi, Dario Luca Lauretti, A Cicorelli, Alessandro Lunardi, Roberto Cioni, Carlo BartolozziAbstract:Purpose To assess feasibility of Proper Hepatic Artery catheterization using a 3D model obtained from preprocedural computed tomographic angiography (CTA), fused with real-time fluoroscopy, during transarterial chemoembolization of hepatocellular carcinoma.
Y Itai - One of the best experts on this subject based on the ideXlab platform.
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extraHepatic arterial supply to the liver observation with a unified ct and angiography system during temporary balloon occlusion of the Proper Hepatic Artery
Radiology, 1998Co-Authors: Yoshito Takeuchi, Yasuaki Arai, Y Inaba, K Ohno, T Maeda, Y ItaiAbstract:PURPOSE: To evaluate routes of potential extraHepatic arterial supply to the liver. MATERIALS AND METHODS: Twenty-three patients with liver tumors underwent computed tomographic (CT) arteriography of extraHepatic arteries before and after temporary balloon occlusion of the Proper Hepatic Artery. The right inferior phrenic Artery (RIPA), left inferior phrenic Artery (LIPA), superior mesenteric Artery (SMA), celiac axis, and left gastric Artery (LGA) were evaluated. RESULTS: During temporary balloon occlusion of the Proper Hepatic Artery, extraHepatic arterial supply was immediately evident in 22 of 23 patients (96%). The liver was supplied by the RIPA in 17 of 20 patients (85%), by the LIPA in five of six (83%), by the SMA in eight of 16 (50%), by the celiac axis in two of 10 (20%), and by the LGA in one of six (17%). There was no apparent relationship between the enhanced zones supplied by extraHepatic arteries and the presence or absence of nearby tumors. CONCLUSION: ExtraHepatic arterial supply to the l...
Shinichiro Kumita - One of the best experts on this subject based on the ideXlab platform.
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Contribution of extraHepatic collaterals to liver parenchymal circulation after Proper Hepatic Artery embolization.
Journal of gastroenterology and hepatology, 2014Co-Authors: Takahiko Mine, Satoru Murata, Tatsuo Ueda, Minako Takeda, Shiro Onozawa, Hidenori Yamaguchi, Youichi Kawano, Shinichiro KumitaAbstract:Background and Aim To retrospectively evaluate Proper Hepatic Artery embolization, with respect to the development of extraHepatic collaterals. Methods Proper Hepatic Artery embolization was performed in 18 patients with hemorrhagic arterial lesions in the Hepatic hilum. Post-procedural development of extraHepatic collaterals was evaluated by computed tomography or angiography. Embolization data and liver function tests were assessed. The correlation of outcomes with portal venous stenosis, Hepatic failure prior to embolization, elevation of prothrombin time, and insufficient collateral development were analyzed. Results Postoperative bleeding occurred in 17/18 patients, and one was treated for an idiopathic aneurysm of the Proper Hepatic Artery; all treatments achieved technical success. ExtraHepatic collaterals were confirmed in 13 patients. Elevations of liver function test values were transient and returned to baseline within 14 days in patients with collateral development (n = 13), but were unimproved in patients without collaterals (n = 5) (P
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contribution of extraHepatic collaterals to liver parenchymal circulation after Proper Hepatic Artery embolization
Journal of Gastroenterology and Hepatology, 2014Co-Authors: Takahiko Mine, Satoru Murata, Tatsuo Ueda, Minako Takeda, Shiro Onozawa, Hidenori Yamaguchi, Youichi Kawano, Shinichiro KumitaAbstract:Background and Aim To retrospectively evaluate Proper Hepatic Artery embolization, with respect to the development of extraHepatic collaterals. Methods Proper Hepatic Artery embolization was performed in 18 patients with hemorrhagic arterial lesions in the Hepatic hilum. Post-procedural development of extraHepatic collaterals was evaluated by computed tomography or angiography. Embolization data and liver function tests were assessed. The correlation of outcomes with portal venous stenosis, Hepatic failure prior to embolization, elevation of prothrombin time, and insufficient collateral development were analyzed. Results Postoperative bleeding occurred in 17/18 patients, and one was treated for an idiopathic aneurysm of the Proper Hepatic Artery; all treatments achieved technical success. ExtraHepatic collaterals were confirmed in 13 patients. Elevations of liver function test values were transient and returned to baseline within 14 days in patients with collateral development (n = 13), but were unimproved in patients without collaterals (n = 5) (P < 0.001). Portal venous stenosis; prior Hepatic failure; unrecovered, elevation of prothrombin time; and insufficient collateral development were significantly correlated with poor outcomes (P < 0.05, respectively). Conclusions Proper Hepatic Artery embolization is effective for hemostasis, and extraHepatic collateral development is expected. Therefore, this is a safe treatment without prolonged Hepatic ischemic damage, especially in patients without severe portal venous stenosis or prior Hepatic failure.
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Successful Management of a Proper Hepatic Artery Aneurysm by Embolization without Liver Dysfunction
2013Co-Authors: Fumie Sugihara, Satoru Murata, Fumio Uchiyama, Jun Watari, Yutaka Abe, Shinichiro KumitaAbstract:The occurrence of a Hepatic Artery aneurysm (HAA) is rare, accounting for approximately 20% of splanchnic aneurysms. Further, HAA rupture can become a lifethreatening situation. We describe the case of a 65-year-old woman with a Proper Hepatic Artery (PHA) aneurysm, which was managed successfully by transcatheter arterial embolization with microcoils. The patient was asymptomatic, and the lesion was incidentally detected by computed tomography (CT) examination. We successfully performed coil embolization of the PHA aneurysm by balloon occlusion of the common Hepatic Artery. The embolization did not cause complications such as liver dysfunction and liver infarction. Thus, given that transcatheter arterial embolization is minimally invasive, we consider it a valuable method in the initial treatment of an HAA.
