The Experts below are selected from a list of 90 Experts worldwide ranked by ideXlab platform
James E Peacock - One of the best experts on this subject based on the ideXlab platform.
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Pseudallescheria boydii Brain Abscess Successfully Treated with Voriconazole and Surgical Drainage: Case Report and Literature Review of Central Nervous
2016Co-Authors: System Pseudallescheriasis, Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circum-stances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is dif®cult, therapeutic options are lim-ited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the ®rst such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options. The fungi that most commonly cause CNS infections are Candida species and Cryptococcus neoformans [1±3]. However, with the increasing prevalence of immunosuppression (in pa-tients who have undergone organ transplantation, who are re-ceiving chemotherapy for neoplasm, who have AIDS, etc.), other opportunistic fungi have recently emerged as important pathogenic organisms [4±6]. Among these emerging agents, P
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pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage case report and literature review of central nervous system Pseudallescheriasis
Clinical Infectious Diseases, 2000Co-Authors: Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circumstances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is difficult, therapeutic options are limited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the first such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options.
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pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage case report and literature review of central nervous system Pseudallescheriasis
Clinical Infectious Diseases, 2000Co-Authors: Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circumstances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is difficult, therapeutic options are limited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the first such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options. The fungi that most commonly cause CNS infections are Candida species and Cryptococcus neoformans [1‐3]. However, with the increasing prevalence of immunosuppression (in patients who have undergone organ transplantation, who are receiving chemotherapy for neoplasm, who have AIDS, etc.), other opportunistic fungi have recently emerged as important pathogenic organisms [4‐6]. Among these emerging agents, P. boydii is a relatively rare but well-documented potential CNS pathogen. P. boydii (previously known as Allescheria boydii and Petriellidium boydii) and its asexual form, Scedosporium apiospermum (previously Monosporium apiospermum), are ubiquitous saprophytic fungi found in soil, manure, decaying vegetation, and polluted streams [7, 8]. Although P. boydii most often causes cutaneous infection (i.e., mycetoma), invasive disease can occur in immunocompromised hosts, in patients with impaired anatomic barriers (trauma, burns, etc.), and in cases of massive inoculation (near-drowning in polluted water). When P. boydii infection with CNS involvement occurs, it most frequently manifests as either multiple or solitary parenchymal brain abscesses. For the vast majority of patients, the outcome is fatal, even when the diagnosis is promptly established and early and aggressive therapeutic intervention is undertaken [9,
Mark A Nesky - One of the best experts on this subject based on the ideXlab platform.
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Pseudallescheria boydii Brain Abscess Successfully Treated with Voriconazole and Surgical Drainage: Case Report and Literature Review of Central Nervous
2016Co-Authors: System Pseudallescheriasis, Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circum-stances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is dif®cult, therapeutic options are lim-ited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the ®rst such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options. The fungi that most commonly cause CNS infections are Candida species and Cryptococcus neoformans [1±3]. However, with the increasing prevalence of immunosuppression (in pa-tients who have undergone organ transplantation, who are re-ceiving chemotherapy for neoplasm, who have AIDS, etc.), other opportunistic fungi have recently emerged as important pathogenic organisms [4±6]. Among these emerging agents, P
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pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage case report and literature review of central nervous system Pseudallescheriasis
Clinical Infectious Diseases, 2000Co-Authors: Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circumstances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is difficult, therapeutic options are limited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the first such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options.
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pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage case report and literature review of central nervous system Pseudallescheriasis
Clinical Infectious Diseases, 2000Co-Authors: Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circumstances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is difficult, therapeutic options are limited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the first such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options. The fungi that most commonly cause CNS infections are Candida species and Cryptococcus neoformans [1‐3]. However, with the increasing prevalence of immunosuppression (in patients who have undergone organ transplantation, who are receiving chemotherapy for neoplasm, who have AIDS, etc.), other opportunistic fungi have recently emerged as important pathogenic organisms [4‐6]. Among these emerging agents, P. boydii is a relatively rare but well-documented potential CNS pathogen. P. boydii (previously known as Allescheria boydii and Petriellidium boydii) and its asexual form, Scedosporium apiospermum (previously Monosporium apiospermum), are ubiquitous saprophytic fungi found in soil, manure, decaying vegetation, and polluted streams [7, 8]. Although P. boydii most often causes cutaneous infection (i.e., mycetoma), invasive disease can occur in immunocompromised hosts, in patients with impaired anatomic barriers (trauma, burns, etc.), and in cases of massive inoculation (near-drowning in polluted water). When P. boydii infection with CNS involvement occurs, it most frequently manifests as either multiple or solitary parenchymal brain abscesses. For the vast majority of patients, the outcome is fatal, even when the diagnosis is promptly established and early and aggressive therapeutic intervention is undertaken [9,
Ugo Salvolini - One of the best experts on this subject based on the ideXlab platform.
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Mycotic Aneurysms as Lethal Complication of Brain Pseudallescheriasis in a Near-Drowned Child: A CT Demonstration
2015Co-Authors: Anna Messori, Cecilia Lanza, Maurizio De Nicola, Francesco Menichelli, Tiziana Capriotti, Letterio Morabito, Ugo SalvoliniAbstract:and generally lethal. We report a case of a near-drowned child with brain abscesses due to Pseudallescheria boydii, a saprophytic fungus, who died after subarachnoid hemor-rhage occurred. CT showed contrast-enhancing lesions in-dicative of aneurysms of basilar and right posterior cere-bral arteries that could not be appreciated 2 days before. P. boydii is often resistant to commonly used antimycotic drugs. Because CNS infection is frequently associated with near-drowning, early diagnosis and specific therapy are strongly recommended for these patients. Pseudallescheria boydii (previously named Petriel-lidium boydii) and its asexual form, Scedosporium ap-iospermum, are ubiquitous saprophytic fungi that cause chronic subcutaneous infection (ie, true fungal mycetoma, “maduromycosis”) and, less frequently
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mycotic aneurysms as lethal complication of brain Pseudallescheriasis in a near drowned child a ct demonstration
American Journal of Neuroradiology, 2002Co-Authors: Anna Messori, Cecilia Lanza, Maurizio De Nicola, Francesco Menichelli, Tiziana Capriotti, Letterio Morabito, Ugo SalvoliniAbstract:Intracranial true mycotic aneurysms are rare and generally lethal. We report a case of a near-drowned child with brain abscesses due to Pseudallescheria boydii, a saprophytic fungus, who died after subarachnoid hemorrhage occurred. CT showed contrast-enhancing lesions indicative of aneurysms of basilar and right posterior cerebral arteries that could not be appreciated 2 days before. P. boydii is often resistant to commonly used antimycotic drugs. Because CNS infection is frequently associated with near-drowning, early diagnosis and specific therapy are strongly recommended for these patients.
Colin E Mcdougal - One of the best experts on this subject based on the ideXlab platform.
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Pseudallescheria boydii Brain Abscess Successfully Treated with Voriconazole and Surgical Drainage: Case Report and Literature Review of Central Nervous
2016Co-Authors: System Pseudallescheriasis, Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circum-stances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is dif®cult, therapeutic options are lim-ited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the ®rst such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options. The fungi that most commonly cause CNS infections are Candida species and Cryptococcus neoformans [1±3]. However, with the increasing prevalence of immunosuppression (in pa-tients who have undergone organ transplantation, who are re-ceiving chemotherapy for neoplasm, who have AIDS, etc.), other opportunistic fungi have recently emerged as important pathogenic organisms [4±6]. Among these emerging agents, P
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pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage case report and literature review of central nervous system Pseudallescheriasis
Clinical Infectious Diseases, 2000Co-Authors: Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circumstances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is difficult, therapeutic options are limited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the first such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options.
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pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage case report and literature review of central nervous system Pseudallescheriasis
Clinical Infectious Diseases, 2000Co-Authors: Mark A Nesky, Colin E Mcdougal, James E PeacockAbstract:Pseudallescheria boydii and its asexual form, Scedosporium apiospermum, are ubiquitous, saprophytic fungi that commonly cause cutaneous infection. However, in certain circumstances, P. boydii can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is difficult, therapeutic options are limited, and the prognosis is poor. We report a case of Pseudallescheria brain abscess successfully treated with surgical drainage and systemic voriconazole, the first such case to be described in the literature. We also review previously reported cases of CNS Pseudallescheriasis and evaluate therapeutic options. The fungi that most commonly cause CNS infections are Candida species and Cryptococcus neoformans [1‐3]. However, with the increasing prevalence of immunosuppression (in patients who have undergone organ transplantation, who are receiving chemotherapy for neoplasm, who have AIDS, etc.), other opportunistic fungi have recently emerged as important pathogenic organisms [4‐6]. Among these emerging agents, P. boydii is a relatively rare but well-documented potential CNS pathogen. P. boydii (previously known as Allescheria boydii and Petriellidium boydii) and its asexual form, Scedosporium apiospermum (previously Monosporium apiospermum), are ubiquitous saprophytic fungi found in soil, manure, decaying vegetation, and polluted streams [7, 8]. Although P. boydii most often causes cutaneous infection (i.e., mycetoma), invasive disease can occur in immunocompromised hosts, in patients with impaired anatomic barriers (trauma, burns, etc.), and in cases of massive inoculation (near-drowning in polluted water). When P. boydii infection with CNS involvement occurs, it most frequently manifests as either multiple or solitary parenchymal brain abscesses. For the vast majority of patients, the outcome is fatal, even when the diagnosis is promptly established and early and aggressive therapeutic intervention is undertaken [9,
Anna Messori - One of the best experts on this subject based on the ideXlab platform.
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Mycotic Aneurysms as Lethal Complication of Brain Pseudallescheriasis in a Near-Drowned Child: A CT Demonstration
2015Co-Authors: Anna Messori, Cecilia Lanza, Maurizio De Nicola, Francesco Menichelli, Tiziana Capriotti, Letterio Morabito, Ugo SalvoliniAbstract:and generally lethal. We report a case of a near-drowned child with brain abscesses due to Pseudallescheria boydii, a saprophytic fungus, who died after subarachnoid hemor-rhage occurred. CT showed contrast-enhancing lesions in-dicative of aneurysms of basilar and right posterior cere-bral arteries that could not be appreciated 2 days before. P. boydii is often resistant to commonly used antimycotic drugs. Because CNS infection is frequently associated with near-drowning, early diagnosis and specific therapy are strongly recommended for these patients. Pseudallescheria boydii (previously named Petriel-lidium boydii) and its asexual form, Scedosporium ap-iospermum, are ubiquitous saprophytic fungi that cause chronic subcutaneous infection (ie, true fungal mycetoma, “maduromycosis”) and, less frequently
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mycotic aneurysms as lethal complication of brain Pseudallescheriasis in a near drowned child a ct demonstration
American Journal of Neuroradiology, 2002Co-Authors: Anna Messori, Cecilia Lanza, Maurizio De Nicola, Francesco Menichelli, Tiziana Capriotti, Letterio Morabito, Ugo SalvoliniAbstract:Intracranial true mycotic aneurysms are rare and generally lethal. We report a case of a near-drowned child with brain abscesses due to Pseudallescheria boydii, a saprophytic fungus, who died after subarachnoid hemorrhage occurred. CT showed contrast-enhancing lesions indicative of aneurysms of basilar and right posterior cerebral arteries that could not be appreciated 2 days before. P. boydii is often resistant to commonly used antimycotic drugs. Because CNS infection is frequently associated with near-drowning, early diagnosis and specific therapy are strongly recommended for these patients.
