The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Andrew Steptoe - One of the best experts on this subject based on the ideXlab platform.
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cortisol awakening response and Psychosocial Factors a systematic review and meta analysis
Biological Psychology, 2009Co-Authors: Yoichi Chida, Andrew SteptoeAbstract:The magnitude of the cortisol awakening response, a relatively new indicator of hypothalamic-pituitary-adrenocortical (HPA) axis activation, has been related to a number of Psychosocial Factors. But findings have been inconsistent across studies. We systematically reviewed previous studies investigating the association between the cortisol awakening response and Psychosocial Factors. 147 eligible studies from 62 articles were identified. Separate analyses were carried out on the increase in cortisol following waking (CARi), and the integrated volume of cortisol released over the waking period (CARauc). We found that the CARi was positively associated with job stress and general life stress. It was negatively associated with fatigue, burnout, or exhaustion. There were less reliable negative associations between the CARi and positive affects. The CARauc was positively related to general life stress and negatively related to posttraumatic stress syndrome. This review concludes that different Psychosocial Factors are associated with an enhanced or reduced cortisol awakening response.
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Do stress-related Psychosocial Factors contribute to cancer incidence and survival?
NAT CLIN PRACT ONCOL, 2008Co-Authors: Andrew SteptoeAbstract:A substantial body of research has investigated the associations between stress related Psychosocial Factors and cancer outcomes. Previous narrative reviews have been inconclusive. In this Review, we evaluated longitudinal associations between stress and cancer using meta-analytic methods. The results of 165 studies indicate that stress-related Psychosocial Factors are associated with higher cancer incidence in initially healthy populations (P = 0.005); in addition, poorer survival in patients with diagnosed cancer was noted in 330 studies (P < 0.001), and higher cancer mortality was seen in 53 studies (P < 0.001). Subgroup meta-analyses demonstrate that stressful life experiences are related to poorer cancer survival and higher mortality but not to an increased incidence. Stress-prone personality or unfavorable coping styles and negative emotional responses or poor quality of life were related to higher cancer incidence, poorer cancer survival and higher cancer mortality. Site-specific analyses indicate that Psychosocial Factors are associated with a higher incidence of lung cancer and poorer survival in patients with breast, lung, head and neck, hepatobiliary, and lymphoid or hematopoietic cancers. These analyses suggest that stress-related Psychosocial Factors have an adverse effect on cancer incidence and survival, although there is evidence of publication bias and results should be interpreted with caution.
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a bidirectional relationship between Psychosocial Factors and atopic disorders a systematic review and meta analysis
Psychosomatic Medicine, 2008Co-Authors: Yoichi Chida, Mark Hamer, Andrew SteptoeAbstract:Objective:There is growing epidemiological literature focusing on the bidirectional association between Psychosocial Factors and atopic disorders, but no efforts to quantify the relationship systematically have been published.Methods:We searched Medline, PsycINFO, Web of Science, and PubMed up to Ju
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Psychosocial Factors in the development of coronary artery disease
Progress in Cardiovascular Diseases, 2004Co-Authors: Philip C Strike, Andrew SteptoeAbstract:The fact that traditional risk Factors only account for approximately two thirds of cases of coronary artery disease (CAD) has stimulated increasing interest in the relationship between CAD and Psychosocial Factors. Five areas--chronic stress, socioeconomic status (SES), personality, depression, and social support--have been most thoroughly examined. There is evidence to support a causal relationship between chronic stress, SES, depression, and social support and development of CAD. In this article, we discuss the epidemiologic evidence linking Psychosocial Factors and CAD, and review the effects of Psychosocial Factors on several pathophysiologic mechanisms that have been proposed as potential mediators of CAD. The hypothalamic-pituitary-adrenal axis, hypertension and cardiovascular reactivity, endothelial function, inflammatory markers, platelets, coagulation Factors, fibrinogen, lipids, glucose metabolism, and lifestyle Factors have all been implicated in this process. Recently, the first intervention trials have been carried out, although with initially disappointing results. Reducing the cardiovascular risk due to these Psychosocial Factors will be one of the major health care challenges in the future.
Gary J Macfarlane - One of the best experts on this subject based on the ideXlab platform.
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evaluation of work related Psychosocial Factors and regional musculoskeletal pain results from a eular task force
Annals of the Rheumatic Diseases, 2009Co-Authors: Gary J Macfarlane, Paivi Leinoarjas, A J Silman, N Pallewatte, Priyamvada Paudyal, Fiona M Blyth, David Coggon, Geert Crombez, Steven J Linton, Rob J E M SmeetsAbstract:Objectives: To establish whether review articles provide consistent conclusions on associations between work- place Psychosocial Factors and musculoskeletal pain and, if differences exist, to explore whether this is related to the methods used. Methods: Reviews, reported up to February 2007, that included consideration of workplace Psychosocial Factors and upper limb, back or knee pain were identified through searches of multiple databases. The specific work-related Psychosocial Factors considered were job demands, support, job autonomy and job satisfaction. The conclu- sions of each review on one or more of the Psychosocial/ musculoskeletal pain associations were extracted. Results: 15 review articles were identified that considered one or more of the regional pain syndromes included in the study. For back pain, the most consistent conclusions (four reviews positive out of six) were with high job demands and low job satisfaction. The studies of upper limb pain were exclusively related to shoulder and/ or neck pain, and the most consistent positive conclusions were with high and low job demands (four reviews positive out of six and two reviews positive out of three, respectively). For knee pain, only a single review was identified. For individual reviews of back and upper limb pain, there were marked differences in the number of associations concluded to be positive between reviews. Conclusions: The reasons for reviews coming to different conclusions included that they were often evaluating different bodies of evidence (according to their search criteria, the year when the review was conducted, the role that quality assessment played in whether studies contributed to evidence, and the combination of risk Factors addressed in individual studies), but more important was whether the review specified explicit criteria for making conclusions on strength of evidence. These conclusions emphasise the importance of devel- oping standardised methods for conducting such evalua- tions of existing evidence and the importance of new longitudinal studies for clarifying the temporal relationship between Psychosocial Factors and musculoskeletal pain in the workplace.
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low back pain in schoolchildren the role of mechanical and Psychosocial Factors
Archives of Disease in Childhood, 2003Co-Authors: Kath D Watson, Ann C Papageorgiou, Gareth T Jones, Stewart Taylor, Deborah P M Symmons, A J Silman, Gary J MacfarlaneAbstract:Background: Low back pain (LBP) in schoolchildren with no apparent clinical cause is known to be a common problem, but considerably less is understood regarding the aetiology of such pain. Aim: To assess the role of both mechanical and Psychosocial Factors (including emotional and behavioural problems and other somatic pain complaints) in childhood LBP. Methods: A cross sectional study was carried out in a population of 1446 schoolchildren aged 11–14 years. Information on these potential risk Factors for LBP was sought using a self complete questionnaire and a five day bag weight diary. Results: Mechanical Factors such as physical activity and school bag weight were not associated with LBP. However, strong associations with LBP were observed for emotional problems, conduct problems, troublesome headaches, abdominal pain, sore throats, and daytime tiredness. Conclusion: Results suggest that Psychosocial Factors rather than mechanical Factors are more important in LBP occurring in young populations and could possibly be a reflection of distress in schoolchildren.
Heikki Ukkonen - One of the best experts on this subject based on the ideXlab platform.
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Childhood Psychosocial Factors and Coronary Artery Calcification in Adulthood: The Cardiovascular Risk in Young Finns Study.
JAMA pediatrics, 2016Co-Authors: Markus Juonala, Laura Pulkki-råback, Marko Elovainio, Christian Hakulinen, Costan G. Magnussen, Matthew A. Sabin, David Burgner, David L Hare, Olli Hartiala, Heikki UkkonenAbstract:Importance There is increasing evidence supporting the importance of Psychosocial Factors in the pathophysiology of atherosclerotic disease. They have been shown to be associated with the population attributable risk for myocardial infarction. Objective To determine if a score of favorable childhood Psychosocial Factors would be associated with decreased coronary artery calcification in adulthood. Design, Setting, and Participants The analyses were performed in 2015 using data gathered in 1980 and 2008 within the longitudinal Cardiovascular Risk in Young Finns Study. The data source consisted of 311 individuals who had Psychosocial Factors measured at ages 12 years to 18 years and coronary artery calcification measured 28 years later in adulthood. The summary measure of Psychosocial Factors in childhood comprised measures of socioeconomic Factors, emotional Factors, parental health behaviors, stressful events, self-regulation of the child, and social adjustment of the child. Main Outcomes and Measures Coronary artery calcification at ages 40 years to 46 years. Results Of the 311 participants, 48.2% were men. Of the participants, 55 (17.7%) had some calcium observed in their coronary arteries. A 1-SD increase in a favorable summary score of childhood psychological Factors was associated with an adulthood coronary artery calcification probability of 0.85 (95% CI, 0.76-0.95) ( P = .006). This inverse relationship remained significant after adjustment for age, sex, and conventional childhood risk Factors (0.85; 95% CI, 0.74-0.97; P = .02) or for age, sex, adulthood conventional cardiovascular risk Factors, socioeconomic status, social support, and depressive symptoms (0.83; 95% CI, 0.71-0.97; P = .02). Conclusions and Relevance In this longitudinal study, we observed an independent association between childhood Psychosocial well-being and reduced coronary artery calcification in adulthood. A positive childhood Psychosocial environment may decrease cardiovascular risk in adulthood and may represent a potentially modifiable risk determinant.
Hisashi Eguchi - One of the best experts on this subject based on the ideXlab platform.
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work related Psychosocial Factors and metabolic syndrome onset among workers a systematic review and meta analysis
Obesity Reviews, 2018Co-Authors: Kazuhiro Watanabe, Hisashi Eguchi, Asuka Sakuraya, Norito Kawakami, Kotaro Imamura, Emiko Ando, Yumi Asai, Yuka Kobayashi, Norimitsu Nishida, Hideaki ArimaAbstract:Background Work-related Psychosocial Factors have been associated with metabolic syndrome. However, no systematic reviews or meta-analyses have evaluated this association. Methods A systematic literature search was conducted, using PubMed, Embase, PsycINFO, PsycARTICLES and the Japan Medical Abstracts Society. Eligible studies included those that examined the previously mentioned association; had a longitudinal or prospective cohort design; were conducted among workers; provided sufficient data for calculating odds ratios, relative risks or hazard ratios with 95% confidence intervals; were original articles in English or Japanese; and were published no later than 2016. Study characteristics, exposure and outcome variables and association measures of studies were extracted by the investigators independently. Results Among 4,664 identified studies, 8 were eligible for review and meta-analysis. The pooled risk of adverse work-related stress on metabolic syndrome onset was significant and positive (RR = 1.47; 95% CI, 1.22-1.78). Sensitivity analyses limiting only the effects of job strain and shift work also indicated a significant positive relationship (RR = 1.75; 95% CI, 1.09-2.79; and RR = 1.59; 95% CI, 1.00-2.54, P = 0.049 respectively). Conclusion This study reveals a strong positive association between work-related Psychosocial Factors and an elevated risk of metabolic syndrome onset. The effects of job strain and shift work on metabolic syndrome appear to be significant.
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Psychosocial Factors and colleagues perceptions of return to work opportunities for workers with a psychiatric disorder a japanese population based study
Environmental Health and Preventive Medicine, 2017Co-Authors: Hisashi Eguchi, Koji Wada, Yoshiyuki Higuchi, Derek R SmithAbstract:This study examined associations between Psychosocial Factors and the perception that adequate employment opportunities might not be provided for people with limited work capacity due to psychiatric disorders. We conducted an online, cross-sectional survey of 3,710 employed individuals aged 20 to 69 years in Japan. Our survey included the Brief Job Stress Questionnaire and investigated participants’ perception of opportunities in their workplace for individuals with a psychiatric disorder returning to work (colleagues’ negative perception) and Psychosocial Factors (job demand, job control, and workplace social support). Multiple logistic regression analysis was used to evaluate potential associations between Psychosocial Factors and colleagues’ negative perception. Colleagues’ negative perception was associated with low workplace social support (middle tertile: Odds Ratio [OR]: 1.26, 95% Confidence Interval [CI]: 1.12–1.40; low tertile: OR 1.45, 95% CI: 1.32–1.58; p for trend <0.01); low levels of job control (middle tertile: OR 1.22, 95% CI: 1.06–1.38; low tertile: OR 1.64, 95% CI: 1.46–1.81; p for trend <0.01); and no previous experience working with a person with a psychiatric disorder (OR 1.74, 95% CI: 1.60–1.88). Psychosocial Factors may affect colleagues’ perceptions of individuals with a psychiatric disorder returning to work in Japan. Greater consideration of Psychosocial Factors in the workplace may be necessary to facilitate people with a psychiatric disorder successfully returning to work in Japan, as elsewhere.
Christian Hakulinen - One of the best experts on this subject based on the ideXlab platform.
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Childhood Psychosocial Factors and Coronary Artery Calcification in Adulthood: The Cardiovascular Risk in Young Finns Study.
JAMA pediatrics, 2016Co-Authors: Markus Juonala, Laura Pulkki-råback, Marko Elovainio, Christian Hakulinen, Costan G. Magnussen, Matthew A. Sabin, David Burgner, David L Hare, Olli Hartiala, Heikki UkkonenAbstract:Importance There is increasing evidence supporting the importance of Psychosocial Factors in the pathophysiology of atherosclerotic disease. They have been shown to be associated with the population attributable risk for myocardial infarction. Objective To determine if a score of favorable childhood Psychosocial Factors would be associated with decreased coronary artery calcification in adulthood. Design, Setting, and Participants The analyses were performed in 2015 using data gathered in 1980 and 2008 within the longitudinal Cardiovascular Risk in Young Finns Study. The data source consisted of 311 individuals who had Psychosocial Factors measured at ages 12 years to 18 years and coronary artery calcification measured 28 years later in adulthood. The summary measure of Psychosocial Factors in childhood comprised measures of socioeconomic Factors, emotional Factors, parental health behaviors, stressful events, self-regulation of the child, and social adjustment of the child. Main Outcomes and Measures Coronary artery calcification at ages 40 years to 46 years. Results Of the 311 participants, 48.2% were men. Of the participants, 55 (17.7%) had some calcium observed in their coronary arteries. A 1-SD increase in a favorable summary score of childhood psychological Factors was associated with an adulthood coronary artery calcification probability of 0.85 (95% CI, 0.76-0.95) ( P = .006). This inverse relationship remained significant after adjustment for age, sex, and conventional childhood risk Factors (0.85; 95% CI, 0.74-0.97; P = .02) or for age, sex, adulthood conventional cardiovascular risk Factors, socioeconomic status, social support, and depressive symptoms (0.83; 95% CI, 0.71-0.97; P = .02). Conclusions and Relevance In this longitudinal study, we observed an independent association between childhood Psychosocial well-being and reduced coronary artery calcification in adulthood. A positive childhood Psychosocial environment may decrease cardiovascular risk in adulthood and may represent a potentially modifiable risk determinant.
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cumulative effect of Psychosocial Factors in youth on ideal cardiovascular health in adulthood the cardiovascular risk in young finns study
Circulation, 2015Co-Authors: Laura Pulkkiraback, Marko Elovainio, Christian Hakulinen, Laura D Kubzansky, Jari Lipsanen, Mirka Hintsanen, Markus Jokela, Taina Hintsa, Anna Serlachius, Tomi T LaitinenAbstract:Background—The American Heart Association has defined a new metric of ideal cardiovascular health as part of its 2020 Impact Goals. We examined whether Psychosocial Factors in youth predict ideal cardiovascular health in adulthood. Methods and Results—Participants were 477 men and 612 women from the nationwide Cardiovascular Risk in Young Finns Study. Psychosocial Factors were measured from cohorts 3 to 18 years of age at the baseline of the study, and ideal cardiovascular health was examined 27 years later in adulthood. The summary measure of Psychosocial Factors in youth comprised socioeconomic Factors, emotional Factors, parental health behaviors, stressful events, self-regulation of the child, and social adjustment of the child. There was a positive association between a higher number of favorable Psychosocial Factors in youth and greater ideal cardiovascular health index in adulthood (β=0.16; P<0.001) that persisted after adjustment for age, sex, medication use, and cardiovascular risk Factors in chi...
