The Experts below are selected from a list of 291 Experts worldwide ranked by ideXlab platform
Eiki Goto - One of the best experts on this subject based on the ideXlab platform.
-
surgical management of lacrimal Punctal cauterization in chronic gvhd related dry eye with recurrent Punctal Plug extrusion
Bone Marrow Transplantation, 2012Co-Authors: Shigeo Yaguchi, Yoko Ogawa, Mizuka Kamoi, Miki Uchino, Y Tatematsu, E Ohba, Shinichiro Okamoto, Eiki GotoAbstract:Surgical management of lacrimal Punctal cauterization in chronic GVHD-related dry eye with recurrent Punctal Plug extrusion
-
Surgical management of lacrimal Punctal cauterization in chronic GVHD-related dry eye with recurrent Punctal Plug extrusion
Bone Marrow Transplantation, 2012Co-Authors: Shigeo Yaguchi, Yoko Ogawa, Mizuka Kamoi, Miki Uchino, Y Tatematsu, E Ohba, Shinichiro Okamoto, Eiki Goto, K TsubotaAbstract:We investigated the efficacy of lacrimal Punctal occlusion surgery with a cautery device in patients with chronic GVHD (cGVHD)-related dry eye, with recanalization of puncta and recurrent Punctal Plug extrusion. A total of 23 puncta from 14 eyes of 10 patients with chronic GVHD (cGVHD)-related dry eye underwent punctual thermal cauterization with a high-temperature disposable cautery device. All patients were refractory to conventional treatment, including artificial tear eye drops, autologous serum eye drops and vitamin A eye drops, and had a history of recanalization and recurrent Punctal Plug extrusion. The effect of lacrimal Punctal cauterization by thermal cautery device was evaluated by changes in subjective symptom scores, corrected distance visual acuity, Schirmer's test values, fluorescein staining scores, rose bengal staining scores, and tear-film break-up time before and 3 months after the surgery. Subjective symptom scores, Schirmer's test values, fluorescein and rose bengal scores, and tear-film break-up time improved significantly 3 months after the surgery. Recanalization of puncta was not observed in all the cases (0 of 14 eyes, 0%). Lacrimal Punctal cauterization was effective with no recanalization and significant improvements in subjective symptoms and the ocular surface environment in cGVHD-related dry eye patients who had been refractory to conventional treatments.
-
surgical Punctal occlusion with a high heat energy releasing cautery device for severe dry eye with recurrent Punctal Plug extrusion
American Journal of Ophthalmology, 2011Co-Authors: E Ohba, Murat Dogru, Kazuo Tsubota, Yoko Ogawa, Y Tatematsu, Eri Hosaka, Asako Yamazaki, Rie Asaga, Eiki GotoAbstract:Purpose To report the rate of recanalization and the efficacy of Punctal occlusion surgery with a high heat-energy–releasing cautery device in patients with severe dry eye disease and recurrent Punctal Plug extrusion. Design Prospective, interventional case series. Methods Seventy puncta from 44 eyes of 28 dry eye patients underwent Punctal occlusion with thermal cautery. All patients had a history of recurrent Punctal Plug extrusion. A high heat-energy–releasing thermal cautery device (Optemp II V; Alcon Japan) was used for Punctal occlusion surgery. Symptom scores, best-corrected visual acuity, fluorescein staining score, rose bengal staining score, tear film break-up time, and Schirmer test values were compared before and 3 months after the surgery. Rate of Punctal recanalization also was examined. Results Three months after surgical cauterization, symptom score decreased from 3.9 ± 0.23 to 0.56 ± 0.84 ( P P = .003). Fluorescein staining score, rose bengal staining score, tear film break-up time, and the Schirmer test value also improved significantly after the surgery. Only 1 of 70 puncta recanalized after thermal cauterization (1.4%). Conclusions Punctal occlusion with the high heat-energy–releasing cautery device not only was associated with a low recanalization rate, but also with improvements in ocular surface wetness and better visual acuity.
E Ohba - One of the best experts on this subject based on the ideXlab platform.
-
surgical management of lacrimal Punctal cauterization in chronic gvhd related dry eye with recurrent Punctal Plug extrusion
Bone Marrow Transplantation, 2012Co-Authors: Shigeo Yaguchi, Yoko Ogawa, Mizuka Kamoi, Miki Uchino, Y Tatematsu, E Ohba, Shinichiro Okamoto, Eiki GotoAbstract:Surgical management of lacrimal Punctal cauterization in chronic GVHD-related dry eye with recurrent Punctal Plug extrusion
-
Surgical management of lacrimal Punctal cauterization in chronic GVHD-related dry eye with recurrent Punctal Plug extrusion
Bone Marrow Transplantation, 2012Co-Authors: Shigeo Yaguchi, Yoko Ogawa, Mizuka Kamoi, Miki Uchino, Y Tatematsu, E Ohba, Shinichiro Okamoto, Eiki Goto, K TsubotaAbstract:We investigated the efficacy of lacrimal Punctal occlusion surgery with a cautery device in patients with chronic GVHD (cGVHD)-related dry eye, with recanalization of puncta and recurrent Punctal Plug extrusion. A total of 23 puncta from 14 eyes of 10 patients with chronic GVHD (cGVHD)-related dry eye underwent punctual thermal cauterization with a high-temperature disposable cautery device. All patients were refractory to conventional treatment, including artificial tear eye drops, autologous serum eye drops and vitamin A eye drops, and had a history of recanalization and recurrent Punctal Plug extrusion. The effect of lacrimal Punctal cauterization by thermal cautery device was evaluated by changes in subjective symptom scores, corrected distance visual acuity, Schirmer's test values, fluorescein staining scores, rose bengal staining scores, and tear-film break-up time before and 3 months after the surgery. Subjective symptom scores, Schirmer's test values, fluorescein and rose bengal scores, and tear-film break-up time improved significantly 3 months after the surgery. Recanalization of puncta was not observed in all the cases (0 of 14 eyes, 0%). Lacrimal Punctal cauterization was effective with no recanalization and significant improvements in subjective symptoms and the ocular surface environment in cGVHD-related dry eye patients who had been refractory to conventional treatments.
-
surgical Punctal occlusion with a high heat energy releasing cautery device for severe dry eye with recurrent Punctal Plug extrusion
American Journal of Ophthalmology, 2011Co-Authors: E Ohba, Murat Dogru, Kazuo Tsubota, Yoko Ogawa, Y Tatematsu, Eri Hosaka, Asako Yamazaki, Rie Asaga, Eiki GotoAbstract:Purpose To report the rate of recanalization and the efficacy of Punctal occlusion surgery with a high heat-energy–releasing cautery device in patients with severe dry eye disease and recurrent Punctal Plug extrusion. Design Prospective, interventional case series. Methods Seventy puncta from 44 eyes of 28 dry eye patients underwent Punctal occlusion with thermal cautery. All patients had a history of recurrent Punctal Plug extrusion. A high heat-energy–releasing thermal cautery device (Optemp II V; Alcon Japan) was used for Punctal occlusion surgery. Symptom scores, best-corrected visual acuity, fluorescein staining score, rose bengal staining score, tear film break-up time, and Schirmer test values were compared before and 3 months after the surgery. Rate of Punctal recanalization also was examined. Results Three months after surgical cauterization, symptom score decreased from 3.9 ± 0.23 to 0.56 ± 0.84 ( P P = .003). Fluorescein staining score, rose bengal staining score, tear film break-up time, and the Schirmer test value also improved significantly after the surgery. Only 1 of 70 puncta recanalized after thermal cauterization (1.4%). Conclusions Punctal occlusion with the high heat-energy–releasing cautery device not only was associated with a low recanalization rate, but also with improvements in ocular surface wetness and better visual acuity.
Shigeo Yaguchi - One of the best experts on this subject based on the ideXlab platform.
-
surgical management of lacrimal Punctal cauterization in chronic gvhd related dry eye with recurrent Punctal Plug extrusion
Bone Marrow Transplantation, 2012Co-Authors: Shigeo Yaguchi, Yoko Ogawa, Mizuka Kamoi, Miki Uchino, Y Tatematsu, E Ohba, Shinichiro Okamoto, Eiki GotoAbstract:Surgical management of lacrimal Punctal cauterization in chronic GVHD-related dry eye with recurrent Punctal Plug extrusion
-
Surgical management of lacrimal Punctal cauterization in chronic GVHD-related dry eye with recurrent Punctal Plug extrusion
Bone Marrow Transplantation, 2012Co-Authors: Shigeo Yaguchi, Yoko Ogawa, Mizuka Kamoi, Miki Uchino, Y Tatematsu, E Ohba, Shinichiro Okamoto, Eiki Goto, K TsubotaAbstract:We investigated the efficacy of lacrimal Punctal occlusion surgery with a cautery device in patients with chronic GVHD (cGVHD)-related dry eye, with recanalization of puncta and recurrent Punctal Plug extrusion. A total of 23 puncta from 14 eyes of 10 patients with chronic GVHD (cGVHD)-related dry eye underwent punctual thermal cauterization with a high-temperature disposable cautery device. All patients were refractory to conventional treatment, including artificial tear eye drops, autologous serum eye drops and vitamin A eye drops, and had a history of recanalization and recurrent Punctal Plug extrusion. The effect of lacrimal Punctal cauterization by thermal cautery device was evaluated by changes in subjective symptom scores, corrected distance visual acuity, Schirmer's test values, fluorescein staining scores, rose bengal staining scores, and tear-film break-up time before and 3 months after the surgery. Subjective symptom scores, Schirmer's test values, fluorescein and rose bengal scores, and tear-film break-up time improved significantly 3 months after the surgery. Recanalization of puncta was not observed in all the cases (0 of 14 eyes, 0%). Lacrimal Punctal cauterization was effective with no recanalization and significant improvements in subjective symptoms and the ocular surface environment in cGVHD-related dry eye patients who had been refractory to conventional treatments.
Shigeru Kinoshita - One of the best experts on this subject based on the ideXlab platform.
-
Outcome of Punctal Plug occlusion therapy for severe dry eye syndrome
Nippon Ganka Gakkai zasshi, 2020Co-Authors: Kentaro Kojima, Norihiko Yokoi, Jiro Sugita, Yo Nakamura, Yoko Takada, Hiroko Sato, Aoi Komuro, Shigeru KinoshitaAbstract:Punctal occlusion using a silicone Plug is one way of treating tear-deficient dry eye and it has been reported to be effective. We studied the outcome of Punctal Plug occlusion therapy for severe dry eye syndrome at our dry eye clinic. Subjects were 76 eyes of 51 patients [6 eyes of 5 males, 70 eyes of 46 females, mean age: 58.6 +/- 13.4 (mean +/- standard deviation), 49 eyes of 30 patients with Sjögren's syndrome, 27 eyes of 21 patients without Sjögren's syndrome] with severe tear-deficient dry eye who underwent Punctal occlusion using a silicone Plug (Punctal Plug, FCI Co. Ltd, France) during the period of Nov. 1996 to Mar. 2000 at our dry eye clinic. They were under observation for 632 +/- 405 days (mean +/- standard deviation). We studied if there is difference in tolerance between the sizes of Punctal Plug, compared epithelial damage before and after Plug insertion, and studied relief in symptoms using self-assessment. In tolerance of Punctal Plugs, 55.9% of all Plugs were lost during our follow up, but there was no difference in time to loss between the sizes. Epithelial damage was reduced (p < 0.001). Dryness was the most reduced symptom: 26 patients (79%) got better, and only epiphora was increased, with 12 patients (36%) complaining slightly. Punctal Plug occlusion therapy for tear-deficient dry eye is conclusively very effective.
-
Canaliculitis caused by Actinomyces in a case of dry eye with Punctal Plug occlusion
Nippon Ganka Gakkai zasshi, 2020Co-Authors: Maki Takemura, Norihiko Yokoi, Jiro Sugita, Yo Nakamura, Aoi Komuro, Shigeru KinoshitaAbstract:We report a case of canaliculitis caused by Actinomyces odontolyticus in a case of dry eye with Punctal Plugs. A 64-year-old female with Sjögren's syndrome type of dry eye developed lacrimation, congestion in the lower palpebral conjunctiva and corneal epithelial damage in her right eye 30 months after Punctal Plug occlusion. After removal of the Plug from lower punctum in her right eye, white material exuded from the punctum. However, even after the removal of a Plug, corneal epithelial keratopathy did not get worse, implying that the granulation tissue formed by the Plug completely occluded the canaliculus. Actinomices odontolyticus was cultured from the white material. One week after topical antibiotic treatment, conjunctival congestion and irritation were resolved. This report indicates the possibility of canaliculitis as a complication of Punctal Plug occlusion. Careful observation is necessary after Punctal occlusion with Punctal Plugs.
-
Comparison of extrusion rate for two different design of Punctal Plugs
Nippon Ganka Gakkai zasshi, 2020Co-Authors: Masakazu Nishii, Norihiko Yokoi, Jiro Sugita, Kentaro Kojima, Yo Nakamura, Aoi Komuro, Shigeru KinoshitaAbstract:Punctal occlusion using a silicone Plug is an effective treatment for severe tear-deficient dry eye. At present, Plugs from two companies are available in Japan [Eagle Plug(EP); Eagle Vision, Punctal Plug(PP); FCI]. We compared the extrusion rate between EP and PP in our dry eye clinic. Subjects were 20 eyes of 18 patients for EP [5 eyes from 5 males, 15 eyes from 13 females, age: 58.1 +/- 17.5(mean +/- standard deviation)] and 76 eyes of 51 patients for PP (6 eyes from 5 males, 70 eyes from 46 females, age: 58.6 +/- 13.4), 62 eyes from 44 patients with Sjögren syndrome, 34 eyes from 25 patients with non-Sjögren syndrome with severe tear-deficient dry eye treated for the period of November 1996 to February 2002 in our dry eye clinic. We compared the extrusion rate for each Plug and necessity of reinsertion of the Plug. In the examination for EP, 72.2% Plugs were extruded during the follow-up periods, and the average period(59 days) until the extrusion was significantly shorter than for PP(p < 0.0001). In the examination for PP, 55.9% were extruded, and the average period until the extrusion was 287 days. Significant improvement of corneal epithelial damage was seen with PP after insertion of the Plug. For the PP, reinsertion of Plugs was sometimes impossible, probably because of the granulation formed inside the canaliculus, while for EP, reinsertion of the Plugs was possible for all cases. EP becomes extruded more easily than PP, and PP is seems for to form granulation more easily.
-
Clinical investigation of extrusion rate and other complications associated with Punctal Plug F
Japanese Journal of Ophthalmology, 2014Co-Authors: Kimura K, Norihiko Yokoi, Aoi Komuro, Inagaki K, Sonomura Y, Shigeru KinoshitaAbstract:To investigate the effectiveness, extrusion rate and other complications of Punctal Plug F (PPF) compared with Punctal Plug (PP), Super-Flex Plug (SFP) and SuperEagle Plug (SEP). This study involved 31 eyes of 24 dry-eye patients treated with PPF at the dry-eye clinic of Kyoto Prefectural University of Medicine, Kyoto, Japan. Intracanalicular migration rate, extrusion rate, granulation rate, accumulation of soft whitish material and enlargement of punctum size after Punctal-Plug extrusion were investigated and compared with previously published results of PP, SFP and SEP. No migration was observed in the PPF cases at the time of insertion. The extrusion rate was 43.5% during follow-up periods. The average time to extrusion was 158.2 +/- 175.7 (mean +/- SD) days, and the time until 50% of Plugs were extruded was 234 days, longer than that in the SFP cases (p = 0.0012). Granulation was seen in 4.3% of the eyes, but the frequency was lower than in the PP(19%, p = 0.015) and SEP cases (34.5%, p < 0.0001). No soft whitish material was seen around the PPF-cases' Plugs yet significant, post-extrusion punctum size (mm) enlargement (0.78 +/- 0.14) was observed compared to pre-insertion(0.61 +/- 0.18, p < 0.001). Our findings show that insertion of the PPF was easy and without intracanalicular migration, harder to extrude, similar to the PP, yet less susceptible to granulation formation compared with the PP.
-
Treatment progress of large-size puncta and clinical investigation of the extrusion rate and other complications associated with large-size Punctal Plugs
Japanese Journal of Ophthalmology, 2014Co-Authors: Kimura K, Norihiko Yokoi, Aoi Komuro, Inagaki K, Sonomura Y, Hiroaki Kato, Jun Yamada, Shigeru KinoshitaAbstract:One complication of Punctal Plug occlusion (PPO) is enlargement of the punctum. The purpose of the present study was to investigate large-size (over 1.0 mm) puncta after Punctal Plug extrusion. This study involved the treatment progress of 74 large-size (over 1.0 mm) puncta in 55 eyes of 46 patients who underwent PPO. The extrusion rate and other complications of the total 133 Punctal Plugs used for those puncta were investigated. Of the 74 puncta, 33 (44%) achieved occlusion by PPO alone, 20 (27%) achieved perfect occlusion of granulation, and 21 (29%) required surgical Punctal occlusion. Although larger or longer Punctal Plug sizes have been used for PPO, the average elapsed time until extrusion was 143.5 +/- 217.0 (mean +/- SD) days, and the time until 50% of the Plugs were extruded was 50 days. No significant extrusion rate was found among the Punctal Plugs, and there was 0% migration rate. Granulation was observed in 20.3% of the Plugs, yet no soft whitish material was seen around the Plugs. The findings of this study show that large-size puncta can successfully be occluded for a fixed period of time following PPO.
Yoko Ogawa - One of the best experts on this subject based on the ideXlab platform.
-
surgical management of lacrimal Punctal cauterization in chronic gvhd related dry eye with recurrent Punctal Plug extrusion
Bone Marrow Transplantation, 2012Co-Authors: Shigeo Yaguchi, Yoko Ogawa, Mizuka Kamoi, Miki Uchino, Y Tatematsu, E Ohba, Shinichiro Okamoto, Eiki GotoAbstract:Surgical management of lacrimal Punctal cauterization in chronic GVHD-related dry eye with recurrent Punctal Plug extrusion
-
Surgical management of lacrimal Punctal cauterization in chronic GVHD-related dry eye with recurrent Punctal Plug extrusion
Bone Marrow Transplantation, 2012Co-Authors: Shigeo Yaguchi, Yoko Ogawa, Mizuka Kamoi, Miki Uchino, Y Tatematsu, E Ohba, Shinichiro Okamoto, Eiki Goto, K TsubotaAbstract:We investigated the efficacy of lacrimal Punctal occlusion surgery with a cautery device in patients with chronic GVHD (cGVHD)-related dry eye, with recanalization of puncta and recurrent Punctal Plug extrusion. A total of 23 puncta from 14 eyes of 10 patients with chronic GVHD (cGVHD)-related dry eye underwent punctual thermal cauterization with a high-temperature disposable cautery device. All patients were refractory to conventional treatment, including artificial tear eye drops, autologous serum eye drops and vitamin A eye drops, and had a history of recanalization and recurrent Punctal Plug extrusion. The effect of lacrimal Punctal cauterization by thermal cautery device was evaluated by changes in subjective symptom scores, corrected distance visual acuity, Schirmer's test values, fluorescein staining scores, rose bengal staining scores, and tear-film break-up time before and 3 months after the surgery. Subjective symptom scores, Schirmer's test values, fluorescein and rose bengal scores, and tear-film break-up time improved significantly 3 months after the surgery. Recanalization of puncta was not observed in all the cases (0 of 14 eyes, 0%). Lacrimal Punctal cauterization was effective with no recanalization and significant improvements in subjective symptoms and the ocular surface environment in cGVHD-related dry eye patients who had been refractory to conventional treatments.
-
surgical Punctal occlusion with a high heat energy releasing cautery device for severe dry eye with recurrent Punctal Plug extrusion
American Journal of Ophthalmology, 2011Co-Authors: E Ohba, Murat Dogru, Kazuo Tsubota, Yoko Ogawa, Y Tatematsu, Eri Hosaka, Asako Yamazaki, Rie Asaga, Eiki GotoAbstract:Purpose To report the rate of recanalization and the efficacy of Punctal occlusion surgery with a high heat-energy–releasing cautery device in patients with severe dry eye disease and recurrent Punctal Plug extrusion. Design Prospective, interventional case series. Methods Seventy puncta from 44 eyes of 28 dry eye patients underwent Punctal occlusion with thermal cautery. All patients had a history of recurrent Punctal Plug extrusion. A high heat-energy–releasing thermal cautery device (Optemp II V; Alcon Japan) was used for Punctal occlusion surgery. Symptom scores, best-corrected visual acuity, fluorescein staining score, rose bengal staining score, tear film break-up time, and Schirmer test values were compared before and 3 months after the surgery. Rate of Punctal recanalization also was examined. Results Three months after surgical cauterization, symptom score decreased from 3.9 ± 0.23 to 0.56 ± 0.84 ( P P = .003). Fluorescein staining score, rose bengal staining score, tear film break-up time, and the Schirmer test value also improved significantly after the surgery. Only 1 of 70 puncta recanalized after thermal cauterization (1.4%). Conclusions Punctal occlusion with the high heat-energy–releasing cautery device not only was associated with a low recanalization rate, but also with improvements in ocular surface wetness and better visual acuity.
