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Sung Ho Jang - One of the best experts on this subject based on the ideXlab platform.
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relationships among language ability the arcuate fasciculus and lesion volume in patients with Putaminal Hemorrhage a diffusion tensor imaging study
Journal of Integrative Neuroscience, 2021Co-Authors: Min Jye Cho, Sung Ho JangAbstract:Relationships among language ability, arcuate fasciculus and lesion volume were investigated by use of diffusion tensor tractography in patients with Putaminal Hemorrhage. Thirty-three right-handed patients within six weeks of Hemorrhage onset were recruited. Correlation of the aphasia quotient with subset (fluency, comprehension, repetition, naming) scores, diffusion tensor tractography parameters and lesion volume of patients, aphasia quotient (r = 0.446) with subset (naming: r = 0.489) score had moderate positive correlations with fractional anisotropy of the left arcuate fasciculus. The aphasia quotient subset (repetition) score had a strong positive correlation with fractional anisotropy of the left arcuate fasciculus (r = 0.520), whereas, aphasia quotient subset (fluency and comprehension) scores had no significant correlations with fractional anisotropy of the left arcuate fasciculus after Benjamini-Hochberg correction. Aphasia quotient (r = 0.668) with subset (fluency: r = 0.736, comprehension: r = 0.739, repetition: r = 0.649, naming: r = 0.766) scores had strong positive correlations with the tract volume of the left arcuate fasciculus and strong negative correlations with lesion volume (r = -0.521, fluency: r = -0.520, comprehension: r = -0.513, repetition: r = -0.518, naming: r = -0.562). Fractional anisotropy of the left arcuate fasciculus had a moderate negative correlation with lesion volume (r = -0.462), whereas the tract volume of the left arcuate fasciculus had a strong negative correlation with lesion volume (r = -0.700). According to the result of mediation analysis, tract volume of the left arcuate fasciculus fully mediated the effect of lesion volume on the aphasia quotient. Regarding the receiver operating characteristic curve, the lesion volume cut-off value was 29.17 cm3 and the area under the curve (0.74), sensitivity (0.77) and specificity (0.80) were higher than those of fractional anisotropy, tract volume and aphasia quotient cut-off values. It was found that level of language disability was related to lesion volume as well as to injury severity of arcuate fasciculus in the dominant hemisphere of patients with Putaminal Hemorrhage. In particular, the tract volume of the arcuate fasciculus in the dominant hemisphere fully mediated the effect of lesion volume on language ability. Additionally, a lesion volume of approximately 30 cm3 was helpful in discriminating arcuate fasciculus discontinuation in the dominant hemisphere.
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difference of recovery course of motor weakness according to state of corticospinal tract in Putaminal Hemorrhage
Neuroscience Letters, 2017Co-Authors: Sung Ho Jang, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Jiwon Park, Won Hee Choi, You Sung SeoAbstract:Abstract Objectives We investigated differences in recovery course of motor weakness according to the state of the corticospinal tract (CST) in Putaminal Hemorrhage, using diffusion tensor tractography (DTT). Methods We recruited 36 patients with complete weakness of the affected extremities at onset. The patients were classified into two groups according to the findings of DTT for the CST at chronic stage: group A- preserved integrity of the CST around the lesion, and group B- discontinued integrity of the CST. Motor function of the affected extremities was measured over a six month period using the Motricity Index (MI). Results The MI scores differed significantly each month, except at the onset, between group A and group B (p 0.05). The degree of difference between months was as follows: onset ∼1 month, 1 month ∼2 months, 2 months ∼3 months, and 3 months ∼4 months. Conclusions Patients with preserved integrity of the CST showed better motor function than patients with discontinued integrity of the CST. In both groups, significant motor recovery was achieved during the first four months after onset. In addition, the most rapid motor recovery occurred during the first month and then decreased gradually with the passage of time.
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change of an injured corticospinal tract during 3 weeks rehabilitation after Putaminal Hemorrhage
American Journal of Physical Medicine & Rehabilitation, 2017Co-Authors: Sung Ho Jang, Younghyeon Kwon, So Young KwakAbstract:A 51-yr-old, right-handed woman presented with right hemiplegia due to a Putaminal Hemorrhage in the left hemisphere (Fig. 1A). She underwent conservative management at the department of neurosurgery of a university hospital. The patient showed moderate weakness of the right limbs 2 wks after the in
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difference of injury of the corticospinal tract according to surgical or conservative treatment in patients with Putaminal Hemorrhage
International Journal of Neuroscience, 2016Co-Authors: Ah Young Lee, Chul Hoon Chang, Young Jin Jung, Seong Ho Kim, Byung Yun Choi, Sung Ho JangAbstract:Objective: We investigated difference of injury of the corticospinal tract (CST) according to surgical or conservative treatment in patients with Putaminal Hemorrhage (PH), using diffusion tensor tractography (DTT). Methods: Forty-six patients with PH (hematoma volume on the brain CT: 20–40 ml) were recruited. Patients were classified as the surgical treatment group and the conservative treatment group. The hematoma volume on the initial brain CT (median 2 hours after onset; range 1–14 hours) and volumes of the hematoma, the total lesion and the peri-hematomal edema volume on the follow-up brain magnetic resonance imaging (MRI) (median 23.5 days after onset; range 12–46 days) were estimated. Diffusion tensor imaging was performed and we defined the injury of the CST in terms of the configuration or abnormal DTT parameters. Results: In the conservative treatment group, the total lesion volume on the brain MRI was increased compared with the hematoma volume on the initial brain CT (p < 0.05). On brain MRI, ...
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predictability of motor outcome according to the time of motor evoked potentials from the onset of stroke in patients with Putaminal Hemorrhage
Annals of Rehabilitation Medicine, 2015Co-Authors: Yong Min Kwon, Sung Ho Jang, Jung Won LeeAbstract:OBJECTIVE: To determine the predictability of motor evoked potentials (MEP) in patients with Putaminal Hemorrhage (PH) according to the time of MEP from the onset of stroke. METHODS: Sixty consecutive patients with PH from January 2006 to November 2013 were retrospectively reviewed. Motor function of affected extremities was measured at onset time and at six months after the onset. Patients were classified into two groups according to the time of MEP from the onset of stroke: early MEP group (within 15 days from onset) and late MEP group (16-30 days from onset). Patients were also classified into two groups according to the presence of MEP on the affected abductor pollicis brevis (APB): MEP (+) group-patients (showing MEP in the affected APB) and MEP (-) group-patients (no MEP in the affected APB). Motor outcome was compared between the two early and late MEP groups or between the presence and absence of MEP in the affected APB groups. RESULTS: For patients with MEP (+), a larger portion in the late MEP group showed good prognosis compared to the early MEP group (late MEP, 94.4%; early MEP, 80%). In contrast, in patients with MEP (-), a larger portion of patients in the late MEP group showed bad prognosis compared to the early MEP group (late MEP, 80%; early MEP, 71.4%). No significant improvement of MI between MEP (+) and MEP (-) was observed when MEP was performed early or late. CONCLUSION: Our results revealed that the predictability of motor outcome might be better if MEP is performed late compared to that when MEP is performed early in patients with PH.
Chul Hoon Chang - One of the best experts on this subject based on the ideXlab platform.
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abstract tp544 differences in ascending reticular activating systems between persistent vegetative and minimally conscious states following Putaminal Hemorrhage
Stroke, 2019Co-Authors: Chul Hoon ChangAbstract:Object: Investigated differences in ascending reticular activating systems(ARAS) of persistent vegetative state(PVS) and minimally conscious states(MCS) following Putaminal Hemorrhage(PH) Method: 1...
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difference of recovery course of motor weakness according to state of corticospinal tract in Putaminal Hemorrhage
Neuroscience Letters, 2017Co-Authors: Sung Ho Jang, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Jiwon Park, Won Hee Choi, You Sung SeoAbstract:Abstract Objectives We investigated differences in recovery course of motor weakness according to the state of the corticospinal tract (CST) in Putaminal Hemorrhage, using diffusion tensor tractography (DTT). Methods We recruited 36 patients with complete weakness of the affected extremities at onset. The patients were classified into two groups according to the findings of DTT for the CST at chronic stage: group A- preserved integrity of the CST around the lesion, and group B- discontinued integrity of the CST. Motor function of the affected extremities was measured over a six month period using the Motricity Index (MI). Results The MI scores differed significantly each month, except at the onset, between group A and group B (p 0.05). The degree of difference between months was as follows: onset ∼1 month, 1 month ∼2 months, 2 months ∼3 months, and 3 months ∼4 months. Conclusions Patients with preserved integrity of the CST showed better motor function than patients with discontinued integrity of the CST. In both groups, significant motor recovery was achieved during the first four months after onset. In addition, the most rapid motor recovery occurred during the first month and then decreased gradually with the passage of time.
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difference of injury of the corticospinal tract according to surgical or conservative treatment in patients with Putaminal Hemorrhage
International Journal of Neuroscience, 2016Co-Authors: Ah Young Lee, Chul Hoon Chang, Young Jin Jung, Seong Ho Kim, Byung Yun Choi, Sung Ho JangAbstract:Objective: We investigated difference of injury of the corticospinal tract (CST) according to surgical or conservative treatment in patients with Putaminal Hemorrhage (PH), using diffusion tensor tractography (DTT). Methods: Forty-six patients with PH (hematoma volume on the brain CT: 20–40 ml) were recruited. Patients were classified as the surgical treatment group and the conservative treatment group. The hematoma volume on the initial brain CT (median 2 hours after onset; range 1–14 hours) and volumes of the hematoma, the total lesion and the peri-hematomal edema volume on the follow-up brain magnetic resonance imaging (MRI) (median 23.5 days after onset; range 12–46 days) were estimated. Diffusion tensor imaging was performed and we defined the injury of the CST in terms of the configuration or abnormal DTT parameters. Results: In the conservative treatment group, the total lesion volume on the brain MRI was increased compared with the hematoma volume on the initial brain CT (p < 0.05). On brain MRI, ...
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Is thalamocortical tract injury responsible for memory impairment in a patient with Putaminal Hemorrhage
Neural Regeneration Research, 2015Co-Authors: Hyeok Gyu Kwon, Chul Hoon ChangAbstract:Prior to development of diffusion tensor imaging (DTI), there were many difficulties in visualization and estimation of the Papez circuit in the live human brain (Papez, 1995). Diffusion tensor tractography (DTT), derived from DTI, allows for identification and visualization of neural tracts in the Papez circuit (Concha et al., 2005; Kwon et al., 2010; Granziera et al., 2011; Jang and Yeo, 2013; Jang et al., 2014a). In the current study, using DTT, we report on a patient who showed injured thalamocortical tract between the anterior thalamic nuclei and the cingulate gyrus following a Putaminal Hemorrhage. A 55-year-old male patient received conservative management for a Putaminal Hemorrhage in the left hemisphere (Figure 1A). He showed cognitive dysfunction since the onset of Putaminal Hemorrhage. Results of evaluation at 5 weeks after onset using the Memory Assessment Scale (MAS) which is a comprehensive standardized memory assessment battery that consists of four memory subsets: global memory, short-term memory, verbal memory, and visual memory indicate severe memory impairment (global memory: 71 (3%ile), short term memory: 75 (5%ile), verbal memory: 64 (1%ile), and visual memory: 94 (35%ile)) although Wechsler Adult Intelligence Scale (IQ) was within normal range as 94 (Williams, 1991). Figure 1 Brain CT, T2-weighted MR images, and diffusion tensor tractography (DTT) images of a 55-year-old male patient with a Putaminal Hemorrhage in the left hemisphere exhibiting cognitive dysfunction. DTI data was acquired at 5 weeks after onset using a 6-channel head coil on a 1.5 T Philips Gyroscan Intera (Philips, Ltd., Best, the Netherlands) with single-shot echo-planar imaging. For each of the 32 non-collinear diffusion sensitizing gradients, we acquired 70 contiguous slices parallel to the anterior commissure-posterior commissure line. Imaging parameters were as follows: acquisition matrix = 96 × 96; reconstructed to matrix = 192 × 192; field of view = 240 × 240 mm2; repetition time (TR) = 10,398 ms; echo time (TE) = 72 ms; parallel imaging reduction factor (SENSE factor) = 2; echo planar imaging factor = 59; b = 1,000 s/mm2; and a slice thickness of 2.5 mm. Fiber tracking was performed using a probabilistic tractography method based, and applied in the present study utilizing tractography routines implemented in Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB) Software Library (FSL; www.fmrib.ox.ac.uk/fsl). Each neural tract of the Papez circuit was determined by selection of fibers passing through seed and target regions of interest (ROIs) (Concha et al., 2005; Kwon et al., 2010; Jang and Yeo, 2013). We manually drew the ROIs as follows: thalamocortical tract: seed ROI – the cingulate gyrus, first target ROI – anterior limb of internal capsule, second target ROI – anterior thalamic nuclei; fornix: seed ROI – mammillary body, target ROI – crus of fornix; mammillothalamic tract: seed ROI – anterior thalamic nucleus, first target ROI – portion of isolated mammillothalamic tract, second target ROI – mammillary body; cingulum: seed ROI – middle portion of the cingulum, target ROI – posterior portion of the cingulum. Out of 5,000 samples generated from a seed voxel, results were visualized at the threshold of 5 streamline through each voxel for analysis. In the right hemisphere, the whole Papez circuit including the thalamocortical tract, cingulum, fornix, and mammillothalamic tract were reconstructed. By contrast, the thalamocortical tract was not reconstructed in the left hemisphere due to the Putaminal Hemorrhage. The Papez circuit, described by James Papez in 1937, is known to play important roles in control of emotion and memory (Papez, 1995). The pathway of the Papez circuit was reported as follows: hippocampal formation – fornix – mammillary bodies – anterior thalamic nuclei – cingulate gyrus – cingulum – parahippocampal gyrus – hippocampus (Papez, 1995). Previous studies using DTT have reported on injury of a portion of the Papez circuit including fornix, mammillothalamic tract and cingulum (Wang et al., 2008; Yeo and Jang, 2013; Jang et al., 2014a, b; Kwon et al., 2014). Regarding the thalamocortical tract between anterior thalamic nuclei and cingulate gyrus, a recent study reported on a patient who showed thinned thalamocortical tract and non-reconstruction of the mammillothalamic tract following anterior thalamic infarction (Jang et al., 2014a). In the current study, we investigated DTT findings of the neural tracts of the Papez circuit and found injury of the left thalamocortical tract between anterior thalamic nuclei and cingulate gyrus. We think that this patient's memory impairment was mainly the result of the injury of this tract in the Papez circuit. To the best of our knowledge, this is the first study to demonstrate neural tract injuries of the Papez circuit following an intracerebral Hemorrhage. We think that further studies involving larger numbers of patients and recovery of memory function using follow up DTT are necessary. This study was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology, No. 2012R1A1A4A01001873.
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characteristics of injury of the corticospinal tract and corticoreticular pathway in hemiparetic patients with Putaminal Hemorrhage
BMC Neurology, 2014Co-Authors: Jin Sun Yoo, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Sung Ho JangAbstract:No study on the characteristics of injury of the corticospinal tract (CST) or corticoreticular pathway (CRP) in patients with Putaminal Hemorrhage has been reported. In this study, using diffusion tensor tractography, we attempted to investigate the characteristics of injury of the CST and CRP in hemiparetic patients with Putaminal Hemorrhage. Fifty seven consecutive patients with Putaminal Hemorrhage and 57 healthy control subjects were recruited for this study. Diffusion tensor imaging was performed during the early period (8 ~ 30 days) after onset. We defined injury of the CST or CRP in terms of the configuration (discontinuation of a neural tract) or abnormal DTT parameters (the fractional anisotrophy value or fiber number was more than two standard deviations lower than that of normal control subjects). The Motricity Index, the modified Brunnstrom Classification, and the Functional Ambulation Categories were used for evaluation of motor function. Among 57 patients, injury of the CST was found in 41 patients (71.9%) and injury of the CRP was found in 50 patients (87.8%), respectively, and 37 patients (64.9%) had injury of both the CST and CRP. All three motor functions of patients with injury of both the CST and CRP were significantly lower than those of patients with injury of either the CST or CRP (p < 0.05). Our results indicate that the Putaminal Hemorrhage frequently accompanies injury of both the CST and CRP, and the CRP appears to be more vulnerable to Putaminal Hemorrhage than the CST. These findings suggest the necessity for evaluation of both the CRP and the CST in patients with Putaminal Hemorrhage.
Shigeru Sonoda - One of the best experts on this subject based on the ideXlab platform.
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influence of hematoma volume and age on cognitive functions and adl after Putaminal Hemorrhage
Journal of Stroke & Cerebrovascular Diseases, 2020Co-Authors: Makoto Watanabe, Shinichiro Maeshima, Kotaro Takeda, Takaji Suzuki, Shigeru SonodaAbstract:Abstract Background and objective After cerebral Hemorrhage, cognitive functions and activities of daily living (ADL) are affected by various factors, including hematoma volume and patient age. In the present study, we investigated the effect of age and hematoma volume on cognitive functions and on ADL. Methods The sample comprised 274 patients (183 men and 91 women; mean age 58.2 ± 12.5 years) with Putaminal Hemorrhage who were hospitalized in a convalescent rehabilitation ward. Hematoma volume was estimated from computed tomography imaging at stroke onset. Cognitive functions were evaluated using Raven's Colored Progressive Matrices test (RCPM) and the Mini-Mental State Examination (MMSE) at hospital admission, while ADL score was assessed at discharge using the Functional Independence Measure motor subscale (FIM-M). In the present study, we classified the patients into six groups according to whether they were non-elderly or elderly (cutoff age, 60 years) and whether their hematoma was small, medium, or large (cutoff volumes, 20 and 40 mL, respectively). Subsequently, the scores on the RCPM, MMSE, and FIM-M were compared among the groups. Results In both age groups, patients with a larger hematoma volume had lower RCPM and MMSE scores. Patients Conclusions In the present study, we demonstrated that advancing age increases the effect of hematoma volume on RCPM and MMSE scores and identified differences in the effects observed on these two scores. Thus, it may be important to use the RCPM alongside the MMSE for patient assessment.
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relationship between hematoma volume and motor impairment in Putaminal Hemorrhage
Journal of Stroke & Cerebrovascular Diseases, 2020Co-Authors: Hitoshi Ohnishi, Shinichiro Maeshima, Kotaro Takeda, Makoto Watanabe, Shigeru SonodaAbstract:Abstract Purpose: Computed tomography (CT) is used for initial assessment of patients with suspected stroke. Motor outcome prediction using the initial CT image is important for clinical rehabilitation. However, there is inconsistency in the results reported by the few publications on hematoma volume and motor outcomes in patients with Putaminal Hemorrhage. To clarify the direction of hematoma and relationship between the hematoma volume and motor outcomes in patients with Putaminal Hemorrhage using an initial CT image, we evaluated the volume of direction of hematoma in 170 patients in the subacute phase after Putaminal Hemorrhage using CT at stroke onset. Methods: The patients were divided into 5 groups according to the direction of the hematoma. For each group, Spearman's correlation coefficients were calculated to investigate the relationship between hematoma volume and motor outcomes. Motor outcomes were assessed using the motor items of Stroke Impairment Assessment Set, which are impairment indexes for the distal and proximal functions of the upper and lower extremities after stroke. Results: Hematoma volume was significantly correlated with all the motor items in the group whose hematoma extended to the posterior limb of the internal capsule alone (Bonferroni corrected P
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predicting walking ability in hemiplegic patients with Putaminal Hemorrhage an observational study in a rehabilitation hospital
European Journal of Physical and Rehabilitation Medicine, 2020Co-Authors: Shinichiro Maeshima, Sayaka Okamoto, Hideto Okazaki, Shino Mizuno, Shigeru SonodaAbstract:Background In stroke rehabilitation, the most important concern of the patients and their families is whether the patients can walk independently and whether they need braces after discharge. Aim This study aims to investigate the relationship between several types of Putaminal Hemorrhage and walking independence and orthotic therapy in patients with hemiplegia. Design Observational study. Setting Inpatients rehabilitation department, Fujita Health University Nanakuri Memorial Hospital, Japan. Population Total 264 patients with Putaminal Hemorrhage admitted to our hospital. Methods Neurological and cognitive functions were examined as per the stroke scale of the National Institutes of Health and the Mini-mental state examination, respectively. The hematomas were classified into five types, and the volume was measured using computed tomography (CT). Walking ability was evaluated by Functional Ambulation Category (FAC), and walking independence was defined as FAC ≥4. The relationship between the types of hematomas and walking independence and orthotic therapy in patients with hemiplegia with Putaminal Hemorrhage was also analyzed. Results We observed differences within the hematoma types in volume, neurological symptoms, and cognitive function but not in age, sex, and lesion side aspects of these patients-143 of whom could walk independently (FAC≥4) and 121 non-independently. Walking independently and the need for orthosis were closely related to the type of hematoma. Conclusions CT imaging at stroke onset can provide useful information when examining walking independence and indicate necessity for an orthosis at the time of discharge to the rehabilitation ward. Clinical rehabilitation impact This study might help to better understand the role of neuroimaging in stroke rehabilitation.
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factors necessary for independent walking in patients with Putaminal Hemorrhage
Annals of Physical and Rehabilitation Medicine, 2018Co-Authors: Shinichiro Maeshima, Sayaka Okamoto, Hideto Okazaki, Hirokazu Hori, Kei Yagihashi, Ikuko Fuse, Hirofumi Maeda, Yuki Senju, A Kiso, Shigeru SonodaAbstract:Introduction/Background Putaminal haemorrhage accounts for 30%–40% of all cerebral haemorrhages and is responsible for various neurological symptoms, including motor paralysis. Its prognosis varies according to factors such as age, neurological severity, site and size of hematoma, complications, and choice of treatment. We examined the factors related to independent walking in patients with Putaminal Hemorrhage who were admitted to a rehabilitation hospital. Material and method We evaluated 264 patients with thalamic Hemorrhage (172 men and 92 women; age range, 29–88 years) who were admitted to our rehabilitation hospital. The mean duration from symptom onset to rehabilitation hospital admission was 29.9 ± 14.8 days, and the mean rehabilitation hospital stay was 74.6 ± 35.3 days. Patients’ neurological and cognitive functions were examined with the National Institutes of Health Stroke Scale (NIHSS) and Mini-Mental State Examination (MMSE), respectively. The relationship between patients’ scores on these scales and their walking ability at discharge from the rehabilitation hospital was analyzed. Additionally, a decision-tree analysis was used to create a model for predicting independent walking upon referral to the rehabilitation hospital. Results Among the patients, 143 could walk independently and 121 could not. The two patient groups were significantly different in terms of age, duration from symptom onset to rehabilitation hospital admission, hematoma type, hematoma volume, neurological symptoms, and cognitive function. The decision-tree analysis revealed that the patient's age, motor leg of the NIHSS, MMSE score, and hematoma volume were factors that could predict independent walking. Conclusion In patients with Putaminal Hemorrhage, the neurological symptoms, and neuroimaging factors at onset are useful for predicting independent walking.
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Dysphagia Following Putaminal Hemorrhage at a Rehabilitation Hospital.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015Co-Authors: Shinichiro Maeshima, Sayaka Okamoto, Hideto Okazaki, Shiho Mizuno, Naoki Asano, Tetsuya Tsunoda, Mitsuko Masaki, Shinichiro Tanaka, Shigeru SonodaAbstract:Background Dysphagia occurs frequently during the acute phase of cerebral Hemorrhage; however, there are few reports of dysphagia associated with cerebral Hemorrhage in the subacute and chronic phase. We focused on Putaminal Hemorrhage at a rehabilitation hospital and evaluated the relationships between the frequencies of dysphagia, focus, and hematoma volume and type. Methods A hundred patients with Putaminal Hemorrhage referred to our rehabilitation hospital were evaluated. Bedside swallowing assessments (BSAs) were conducted and results were evaluated relative to the information obtained on computed tomography imaging, including hematoma type and volume, and oral intake at the time of admission/discharge from the hospital. Results A regular diet was provided to 48 patients, dysphagia diet to 44 patients, and enteral feeding to 8 patients. There were significant feeding group differences in age, hematoma volume and type, existence of ventricle rupture, neurological manifestation, cognitive function, existence of unilateral neglect and aphasia, initial BSA, activities of daily living (ADL) score using the Functional Independence Measure at the time of admission/discharge from the hospital, and length of stay. At discharge, we provided a regular diet to 81 patients and dysphagia diet to 19 patients. Age and ADL score had the greatest influence on oral intake at the time of discharge from the hospital. Conclusion The prognosis of dysphagia caused by Putaminal Hemorrhage is good, with no patient requiring enteral feeding, although Putaminal Hemorrhage often causes dysphagia. Patient age and ADL score on admission are used to predict the residual factors of dysphagia.
Young Jin Jung - One of the best experts on this subject based on the ideXlab platform.
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difference of recovery course of motor weakness according to state of corticospinal tract in Putaminal Hemorrhage
Neuroscience Letters, 2017Co-Authors: Sung Ho Jang, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Jiwon Park, Won Hee Choi, You Sung SeoAbstract:Abstract Objectives We investigated differences in recovery course of motor weakness according to the state of the corticospinal tract (CST) in Putaminal Hemorrhage, using diffusion tensor tractography (DTT). Methods We recruited 36 patients with complete weakness of the affected extremities at onset. The patients were classified into two groups according to the findings of DTT for the CST at chronic stage: group A- preserved integrity of the CST around the lesion, and group B- discontinued integrity of the CST. Motor function of the affected extremities was measured over a six month period using the Motricity Index (MI). Results The MI scores differed significantly each month, except at the onset, between group A and group B (p 0.05). The degree of difference between months was as follows: onset ∼1 month, 1 month ∼2 months, 2 months ∼3 months, and 3 months ∼4 months. Conclusions Patients with preserved integrity of the CST showed better motor function than patients with discontinued integrity of the CST. In both groups, significant motor recovery was achieved during the first four months after onset. In addition, the most rapid motor recovery occurred during the first month and then decreased gradually with the passage of time.
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difference of injury of the corticospinal tract according to surgical or conservative treatment in patients with Putaminal Hemorrhage
International Journal of Neuroscience, 2016Co-Authors: Ah Young Lee, Chul Hoon Chang, Young Jin Jung, Seong Ho Kim, Byung Yun Choi, Sung Ho JangAbstract:Objective: We investigated difference of injury of the corticospinal tract (CST) according to surgical or conservative treatment in patients with Putaminal Hemorrhage (PH), using diffusion tensor tractography (DTT). Methods: Forty-six patients with PH (hematoma volume on the brain CT: 20–40 ml) were recruited. Patients were classified as the surgical treatment group and the conservative treatment group. The hematoma volume on the initial brain CT (median 2 hours after onset; range 1–14 hours) and volumes of the hematoma, the total lesion and the peri-hematomal edema volume on the follow-up brain magnetic resonance imaging (MRI) (median 23.5 days after onset; range 12–46 days) were estimated. Diffusion tensor imaging was performed and we defined the injury of the CST in terms of the configuration or abnormal DTT parameters. Results: In the conservative treatment group, the total lesion volume on the brain MRI was increased compared with the hematoma volume on the initial brain CT (p < 0.05). On brain MRI, ...
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characteristics of injury of the corticospinal tract and corticoreticular pathway in hemiparetic patients with Putaminal Hemorrhage
BMC Neurology, 2014Co-Authors: Jin Sun Yoo, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Sung Ho JangAbstract:No study on the characteristics of injury of the corticospinal tract (CST) or corticoreticular pathway (CRP) in patients with Putaminal Hemorrhage has been reported. In this study, using diffusion tensor tractography, we attempted to investigate the characteristics of injury of the CST and CRP in hemiparetic patients with Putaminal Hemorrhage. Fifty seven consecutive patients with Putaminal Hemorrhage and 57 healthy control subjects were recruited for this study. Diffusion tensor imaging was performed during the early period (8 ~ 30 days) after onset. We defined injury of the CST or CRP in terms of the configuration (discontinuation of a neural tract) or abnormal DTT parameters (the fractional anisotrophy value or fiber number was more than two standard deviations lower than that of normal control subjects). The Motricity Index, the modified Brunnstrom Classification, and the Functional Ambulation Categories were used for evaluation of motor function. Among 57 patients, injury of the CST was found in 41 patients (71.9%) and injury of the CRP was found in 50 patients (87.8%), respectively, and 37 patients (64.9%) had injury of both the CST and CRP. All three motor functions of patients with injury of both the CST and CRP were significantly lower than those of patients with injury of either the CST or CRP (p < 0.05). Our results indicate that the Putaminal Hemorrhage frequently accompanies injury of both the CST and CRP, and the CRP appears to be more vulnerable to Putaminal Hemorrhage than the CST. These findings suggest the necessity for evaluation of both the CRP and the CST in patients with Putaminal Hemorrhage.
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injury of the cingulum in patients with Putaminal Hemorrhage a diffusion tensor tractography study
Frontiers in Human Neuroscience, 2014Co-Authors: Hyeok Gyu Kwon, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Han Do Lee, Sung Ho JangAbstract:Objectives: Little is known about the pathophysiological mechanisms of cognitive impairment in patients with Putaminal Hemorrhage(PH). Using diffusion tensor tractography(DTT), we investigated injury of the cingulum in patients with PH. Methods: We recruited 63 patients with PH, who were classified according to three groups, based on integrity of the cingulum to the lower portion of the genu of the corpus callosum: group A; preserved integrity, group B; discontinuation of integrity in the affected hemisphere, and group C; discontinuation of integrity in both hemispheres. Results: Thirty four patients(54.0%) belonged to group A, 16 patients(25.4%) to group B, and the remaining 13 patients(20.6%) to group C. Regarding the Mini-Mental State Examination, significant differences were observed between group A and group C, and between group B and group C without significant difference between group A and group B(p<0.05). In terms of the volume of hematoma, significant differences were observed among the three groups(p<0.05). Regarding the most anterior point of the hematoma, significant differences were observed between group A and groups B and C(p<0.05); in contrast, regarding the most point of hematoma, significant differences were observed between group C and groups A and B, respectively(p<0.05). Conclusions: We found that the anterior cingulum is vulnerable to PH. Therefore, our results suggest the necessity for evaluation of the cingulum in patients with PH particularly if the hematoma is large or close to the anterior margin or midline of the brain.
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Anti-Americanism in Korea
2003Co-Authors: Hyeok Gyu Kwon, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Han Do Lee, John J. Foxe, Albert Einstein College, John ColeAbstract:doi: 10.3389/fnhum.2014.00366 Injury of the cingulum in patients with Putaminal Hemorrhage: a diffusion tensor tractography stud
Seong Ho Kim - One of the best experts on this subject based on the ideXlab platform.
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difference of recovery course of motor weakness according to state of corticospinal tract in Putaminal Hemorrhage
Neuroscience Letters, 2017Co-Authors: Sung Ho Jang, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Jiwon Park, Won Hee Choi, You Sung SeoAbstract:Abstract Objectives We investigated differences in recovery course of motor weakness according to the state of the corticospinal tract (CST) in Putaminal Hemorrhage, using diffusion tensor tractography (DTT). Methods We recruited 36 patients with complete weakness of the affected extremities at onset. The patients were classified into two groups according to the findings of DTT for the CST at chronic stage: group A- preserved integrity of the CST around the lesion, and group B- discontinued integrity of the CST. Motor function of the affected extremities was measured over a six month period using the Motricity Index (MI). Results The MI scores differed significantly each month, except at the onset, between group A and group B (p 0.05). The degree of difference between months was as follows: onset ∼1 month, 1 month ∼2 months, 2 months ∼3 months, and 3 months ∼4 months. Conclusions Patients with preserved integrity of the CST showed better motor function than patients with discontinued integrity of the CST. In both groups, significant motor recovery was achieved during the first four months after onset. In addition, the most rapid motor recovery occurred during the first month and then decreased gradually with the passage of time.
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difference of injury of the corticospinal tract according to surgical or conservative treatment in patients with Putaminal Hemorrhage
International Journal of Neuroscience, 2016Co-Authors: Ah Young Lee, Chul Hoon Chang, Young Jin Jung, Seong Ho Kim, Byung Yun Choi, Sung Ho JangAbstract:Objective: We investigated difference of injury of the corticospinal tract (CST) according to surgical or conservative treatment in patients with Putaminal Hemorrhage (PH), using diffusion tensor tractography (DTT). Methods: Forty-six patients with PH (hematoma volume on the brain CT: 20–40 ml) were recruited. Patients were classified as the surgical treatment group and the conservative treatment group. The hematoma volume on the initial brain CT (median 2 hours after onset; range 1–14 hours) and volumes of the hematoma, the total lesion and the peri-hematomal edema volume on the follow-up brain magnetic resonance imaging (MRI) (median 23.5 days after onset; range 12–46 days) were estimated. Diffusion tensor imaging was performed and we defined the injury of the CST in terms of the configuration or abnormal DTT parameters. Results: In the conservative treatment group, the total lesion volume on the brain MRI was increased compared with the hematoma volume on the initial brain CT (p < 0.05). On brain MRI, ...
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characteristics of injury of the corticospinal tract and corticoreticular pathway in hemiparetic patients with Putaminal Hemorrhage
BMC Neurology, 2014Co-Authors: Jin Sun Yoo, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Sung Ho JangAbstract:No study on the characteristics of injury of the corticospinal tract (CST) or corticoreticular pathway (CRP) in patients with Putaminal Hemorrhage has been reported. In this study, using diffusion tensor tractography, we attempted to investigate the characteristics of injury of the CST and CRP in hemiparetic patients with Putaminal Hemorrhage. Fifty seven consecutive patients with Putaminal Hemorrhage and 57 healthy control subjects were recruited for this study. Diffusion tensor imaging was performed during the early period (8 ~ 30 days) after onset. We defined injury of the CST or CRP in terms of the configuration (discontinuation of a neural tract) or abnormal DTT parameters (the fractional anisotrophy value or fiber number was more than two standard deviations lower than that of normal control subjects). The Motricity Index, the modified Brunnstrom Classification, and the Functional Ambulation Categories were used for evaluation of motor function. Among 57 patients, injury of the CST was found in 41 patients (71.9%) and injury of the CRP was found in 50 patients (87.8%), respectively, and 37 patients (64.9%) had injury of both the CST and CRP. All three motor functions of patients with injury of both the CST and CRP were significantly lower than those of patients with injury of either the CST or CRP (p < 0.05). Our results indicate that the Putaminal Hemorrhage frequently accompanies injury of both the CST and CRP, and the CRP appears to be more vulnerable to Putaminal Hemorrhage than the CST. These findings suggest the necessity for evaluation of both the CRP and the CST in patients with Putaminal Hemorrhage.
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injury of the cingulum in patients with Putaminal Hemorrhage a diffusion tensor tractography study
Frontiers in Human Neuroscience, 2014Co-Authors: Hyeok Gyu Kwon, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Han Do Lee, Sung Ho JangAbstract:Objectives: Little is known about the pathophysiological mechanisms of cognitive impairment in patients with Putaminal Hemorrhage(PH). Using diffusion tensor tractography(DTT), we investigated injury of the cingulum in patients with PH. Methods: We recruited 63 patients with PH, who were classified according to three groups, based on integrity of the cingulum to the lower portion of the genu of the corpus callosum: group A; preserved integrity, group B; discontinuation of integrity in the affected hemisphere, and group C; discontinuation of integrity in both hemispheres. Results: Thirty four patients(54.0%) belonged to group A, 16 patients(25.4%) to group B, and the remaining 13 patients(20.6%) to group C. Regarding the Mini-Mental State Examination, significant differences were observed between group A and group C, and between group B and group C without significant difference between group A and group B(p<0.05). In terms of the volume of hematoma, significant differences were observed among the three groups(p<0.05). Regarding the most anterior point of the hematoma, significant differences were observed between group A and groups B and C(p<0.05); in contrast, regarding the most point of hematoma, significant differences were observed between group C and groups A and B, respectively(p<0.05). Conclusions: We found that the anterior cingulum is vulnerable to PH. Therefore, our results suggest the necessity for evaluation of the cingulum in patients with PH particularly if the hematoma is large or close to the anterior margin or midline of the brain.
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Anti-Americanism in Korea
2003Co-Authors: Hyeok Gyu Kwon, Chul Hoon Chang, Byung Yeon Choi, Young Jin Jung, Seong Ho Kim, Han Do Lee, John J. Foxe, Albert Einstein College, John ColeAbstract:doi: 10.3389/fnhum.2014.00366 Injury of the cingulum in patients with Putaminal Hemorrhage: a diffusion tensor tractography stud
