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Linda A Taillon - One of the best experts on this subject based on the ideXlab platform.

  • First-Pass Radionuclide Angiographie Analysis with Two Regions of Interest to Improve Left Ventricular Ejection Fraction Accuracy
    2015
    Co-Authors: Kim A Williams, Todd A. Bryant, Linda A Taillon
    Abstract:

    First-pass Radionuclide angiographie (FPRNA) analysis, using the standard, single-fixed region of interest (ROI)drawn at end-diastole, often underestimates the left ventricular ejection fraction (LVEF) as determined by other standard techniques. This study examined the hypothesis that correction for the anatomic motion of the aortic valve plane toward the apex during systole, which results in im proper inclusion of aortic counts within the single-fixed ROI, using a two-ROI method to compensate for this motion would eliminate this underestimation. Methods: In 70 patients who underwent FPRNA and planar gated equilibrium Radionuclide Angiography (GERNA) on the same day, Fourier transform phase and amplitude images were used to generate functional maps of the aorta and the left ventricle on the FPRNA representative cycle. The region of low amplitude between the aorta and left ventricle, which corresponds to the degree of aortic valve plane motion, was used to guide the manua

  • left ventricular function in patients with coronary artery disease assessed by gated tomographic myocardial perfusion images comparison with assessment by contrast ventriculography and first pass Radionuclide Angiography
    Journal of the American College of Cardiology, 1996
    Co-Authors: Kim A Williams, Linda A Taillon
    Abstract:

    Objectives. This study evaluated the use of gated single-photon emission computed tomographic (SPECT) myocardial perfusion images for determination of left ventricular ejection fraction. Background. Gated SPECT has expanded the applications of myocardial perfusion imaging to include the evaluation of left ventricular size, regional wall motion and regional systolic thickening. Accurate automated or semi-automated methods for quantitation of left ventricular ejection fraction from tomographic perfusion images would provide additional valuable clinical information. Methods. Rest gated SPECT was performed on the stress distribution of technetium-99m sestamibi, using eight frames per cardiac cycle. Mid-horizontal long-axis and vertical long-axis gated tomographic perfusion images were analyzed after digital matrix inversion, which enhances edge detection, for ejection fraction determination. These ejection fractions were compared with those determined by contrast ventriculography (n = 54, including 45 biplane and 9 single plane) and first-pass Radionuclide Angiography (n = 38) in patients with coronary artery disease. Results. Myocardial perfusion SPECT image inversion-derived ejection fractions were slightly lower (2.7 ejection fraction units, p Conclusions. Semiautomated ejection fractions can be obtained from gated SPECT technetium-99m sestamibi perfusion images using the image inversion technique. These results are reproducible and correlate well with results of first-pass Radionuclide Angiography but are closer in value to those obtained with contrast ventriculography.

Kazuo Munakata - One of the best experts on this subject based on the ideXlab platform.

  • global and regional evaluation of systolic and diastolic left ventricular temporal parameters using a novel program for ecg gated myocardial perfusion spect validation by comparison with gated equilibrium Radionuclide Angiography and speckle tracking
    Annals of Nuclear Medicine, 2007
    Co-Authors: Akira Yamamoto, Naoto Takahashi, Kazuo Munakata, Tetsuo Hosoya, Masato Shiiba, Takao Okuyama, Tadashi Kaneshiro, Haruko Tsuruta, Toshi Takama, Masashi Sato
    Abstract:

    Background: A newly developed program, named cardioGRAF, enabled the evaluation of left ventricular (LV) systolic and diastolic temporal parameters for the estimation of heart failure using ECG-gated myocardial perfusion SPECT (GMPS).Objective: The feasibility of those global (g-) and regional (r-) parameters was validated to compare with gated equilibrium Radionuclide Angiography (ERNA) and speckle-tracking radial strain (STS) from echocardiography.Methods: Thirty-three patients were studied using GMPS and ERNA (n=11) or GMPS and STS (n=22). The following g- or r-parameters obtained by cardioGRAF and ERNA or STS were compared: time to en systole (TES), time from end systole to peak filling rate (TPF1), time from 0 to peak filling rate (TPF2), time to peak radial strain (TPS), time from peak strain to peak negative strain rate (TP-SR1), and time from 0 to peak negative strain rate (TP-SR2).Results: All g-parameters were successfully obtained by cardioGRAF and ERNA. The results demonstrated good correlations (g-TES: r=0.79, p<0.005; g-TPF1: r=0.75, p<0.02; TPF2: r=0.83, p<0.005). The differences were 11.9±31.8 ms in g-TES, 19.9±65.4 ms in g-TPF1, and 37.7±67.4 ms in g-TPF2. All r-parameters were successfully obtained by cardioGRAF. Eight patients and 12 segments were excluded because of the inadequate quality of routine echocardiography for STS analysis. However, r-parameters obtained by cardioGRAF were significantly correlated with those of STS (r-TES and r-TPS: r=0.61, p=1×10−8; r-TPF1 and r-TP-SR1: r=0.69, p=3×10−11; r-TPF2 and r-TP-SR2: r=0.76, p=2×10−15). The differences were 21.1±38.2 ms between r-TES and r-TPS, 7.0±123.4 ms between r-TPF1 and r-TP-SR1, and 38.1±111.5 ms between r-TPF2 and r-TP-SR2.Conclusion: The feasibility of evaluating systolic and diastolic temporal parameters by a new program was validated. This program has the potential to evaluate both diastolic and systolic heterogeneous wall motions which express dyssynchrony in heart failure.

  • assessment of left ventricular diastolic function with electrocardiography gated myocardial perfusion spect comparison with multigated equilibrium Radionuclide Angiography
    Journal of Nuclear Cardiology, 2001
    Co-Authors: Shinichiro Kumita, Keiichi Cho, Hidenobu Nakajo, Masahiro Toba, Mariko Uwamori, Sunao Mizumura, Tatsuo Kumazaki, Junko Sano, Shunta Sakai, Kazuo Munakata
    Abstract:

    Background Technetium-labeled myocardial perfusion tracers allow the simultaneous assessment of myocardial perfusion and left ventricular function by electrocardiography (ECG)—gated myocardial perfusion single photon emission computed tomography (SPECT). This study evaluates left ventricular systolic and diastolic function by ECG-gated SPECT with the use of higher framing (32 frames per cardiac cycle) data acquisition.

Sabine Gauvain - One of the best experts on this subject based on the ideXlab platform.

Kim A Williams - One of the best experts on this subject based on the ideXlab platform.

  • First-Pass Radionuclide Angiographie Analysis with Two Regions of Interest to Improve Left Ventricular Ejection Fraction Accuracy
    2015
    Co-Authors: Kim A Williams, Todd A. Bryant, Linda A Taillon
    Abstract:

    First-pass Radionuclide angiographie (FPRNA) analysis, using the standard, single-fixed region of interest (ROI)drawn at end-diastole, often underestimates the left ventricular ejection fraction (LVEF) as determined by other standard techniques. This study examined the hypothesis that correction for the anatomic motion of the aortic valve plane toward the apex during systole, which results in im proper inclusion of aortic counts within the single-fixed ROI, using a two-ROI method to compensate for this motion would eliminate this underestimation. Methods: In 70 patients who underwent FPRNA and planar gated equilibrium Radionuclide Angiography (GERNA) on the same day, Fourier transform phase and amplitude images were used to generate functional maps of the aorta and the left ventricle on the FPRNA representative cycle. The region of low amplitude between the aorta and left ventricle, which corresponds to the degree of aortic valve plane motion, was used to guide the manua

  • left ventricular function in patients with coronary artery disease assessed by gated tomographic myocardial perfusion images comparison with assessment by contrast ventriculography and first pass Radionuclide Angiography
    Journal of the American College of Cardiology, 1996
    Co-Authors: Kim A Williams, Linda A Taillon
    Abstract:

    Objectives. This study evaluated the use of gated single-photon emission computed tomographic (SPECT) myocardial perfusion images for determination of left ventricular ejection fraction. Background. Gated SPECT has expanded the applications of myocardial perfusion imaging to include the evaluation of left ventricular size, regional wall motion and regional systolic thickening. Accurate automated or semi-automated methods for quantitation of left ventricular ejection fraction from tomographic perfusion images would provide additional valuable clinical information. Methods. Rest gated SPECT was performed on the stress distribution of technetium-99m sestamibi, using eight frames per cardiac cycle. Mid-horizontal long-axis and vertical long-axis gated tomographic perfusion images were analyzed after digital matrix inversion, which enhances edge detection, for ejection fraction determination. These ejection fractions were compared with those determined by contrast ventriculography (n = 54, including 45 biplane and 9 single plane) and first-pass Radionuclide Angiography (n = 38) in patients with coronary artery disease. Results. Myocardial perfusion SPECT image inversion-derived ejection fractions were slightly lower (2.7 ejection fraction units, p Conclusions. Semiautomated ejection fractions can be obtained from gated SPECT technetium-99m sestamibi perfusion images using the image inversion technique. These results are reproducible and correlate well with results of first-pass Radionuclide Angiography but are closer in value to those obtained with contrast ventriculography.

Robert J Siegel - One of the best experts on this subject based on the ideXlab platform.

  • correspondence of left ventricular ejection fraction determinations from two dimensional echocardiography Radionuclide Angiography and contrast cineAngiography
    Journal of the American College of Cardiology, 1995
    Co-Authors: Manish M Naik, Ariel Soffer, George A Diamond, Robert J Siegel
    Abstract:

    Objectives. This study assessed the agreement of left ventricular ejection fraction determinations from two-dimensional echocardiography, Radionuclide Angiography and contrast cineAngiography. Background. Previously published reports suggest that twodimensional echocardiography, Radionuclide Angiography and contrast cineAngiography are equally acceptable methods of assessing left ventrieular ejection fraction on the basis of high coefficients of correlation. However, correlation of methods does not necessarily imply agreement. Methods. In a prospective analysis, 25 consecutive subjects all had two-dimensional echocardiography and Radionuclide Angiography performed within 10 days of each other in the cardiology department of a metropolitan community hospital. A retrospective computer search (Medline) revealed seven studies, using the coefficient of correlation (r), comparing two-dimensional echocardiographic left ventricular ejection fraction (n = 268) with Radionuclide angiographic (n = 174) or contrast cineangiographic (n = 119) left ventricular ejection fractions. Results. The eight individual studies (n = 293) comparing two-dimensional echocardiography with either Radionuclide Angiography or contrast cineAngiography exhibited coefficients of correlation ranging from 0.78 to 0.93. Agreement analysis using the method of Bland and Altman was performed by averaging the results obtained from the two techniques and determining how disparate any single ejection fraction was (with 95% confidence limits) from the mean value. Agreement ranged from 23% to 42% around the mean ejection fraction. The average lack of agreement between the two methods for all studies involved was 17%, with an average r value of 0.86. Conclusions. Left ventricular ejection fraction determinations by means of two-dimensional echocardiography, Radionuclide Angiography and contrast cineAngiography exhibit high correlation and only moderate agreement. High correlation does not always imply high agreement. These results suggest that, when validated by agreement analysis, multiple studies may not be necessary in appropriate clinical situations, potentially reducing costs. (J Am Coil Cardiol 1995;25:937-42) Left ventricular ejection fraction is an important clinical variable with respect to diagnosis, prognosis and treatment in various clinical situations. Currently, there are three commonly used methods for determining left ventricular ejection fraction: 1) two-dimensional echocardiography, 2) Radionuclide Angiography, and 3) contrast cineAngiography. Because the clinical situation may dictate using one method versus another, it is important for the clinician to know whether the results of ejection fraction estimates are comparable among the three methods and if they can be used interchangeably. If the answer is yes, this could reduce the need for multiple tests and thereby reduce the cost of health care to the patient. Previously published reports (1-3) suggest that twodimensional echocardiography, Radionuclide Angiography and