The Experts below are selected from a list of 417 Experts worldwide ranked by ideXlab platform
Nilüfer İrem Tunçer - One of the best experts on this subject based on the ideXlab platform.
-
efficiency of piezosurgery technique in miniscrew supported en masse retraction a single centre randomized controlled trial
European Journal of Ophthalmology, 2017Co-Authors: Nilüfer İrem Tunçer, Bahar Füsun Oduncuoğlu, Ayca Armanozcirpici, Julide Sedef Gocmen, Alpdogan KantarciAbstract:Background Piezoelectric surgery is a newly introduced technique for Rapid Tooth Movement. However, the efficiency of this technique has not been investigated on en-masse retraction cases yet. Objective To investigate the efficiency of piezosurgery technique in accelerating miniscrew supported en-masse retraction and study the biological tissue response. In addition, to show if this technique induces a difference in dental, skeletal and soft tissue changes on lateral cephalograms, and in canine and molar rotations, besides intercanine and intermolar widths on dental casts. Design, setting, participants We conducted a randomized, single-centred, parallel-group, controlled trial, requiring upper right and left first premolar extractions on 30 patients above the minimum age of 14 years at the beginning of retraction. Interventions Piezosurgery-assisted versus conventional en-masse retraction anchored from miniscrews placed between second premolars and first molars, bilaterally. Outcomes The main outcome was the en-masse retraction rate. Secondary outcomes were gingival crevicular fluid (GCF) volume and GCF content of receptor activator of nuclear factor κβ ligand (RANKL), changes regarding cephalometric and dental cast variables, and miniscrew success rates. Randomization Accomplished with opaque, sealed envelopes. Blinding Applicable for data assessment only. Recruitment Commenced in February 2013 and ended in October 2014. Results Thirty-one patients were included in the study and divided into 2 groups of piezosurgery (n = 16) and control (n = 15). After 9.3 months of follow-up, no statistically significant difference was observed between groups for neither retraction rates (P = 0.958) nor GCF parameters (P > 0.05). Changes in lateral cephalometric and dental cast variables, and miniscrew success rates did not show significant differences either. Conclusion Based on the results of this study, piezosurgery technique was found to be ineffective in accelerating en-masse retraction, and promoting a difference in the studied GCF parameters, skeletal and dental variables. Registration The trial was not registered. Protocol The full protocol of this PhD thesis study can be accessed from tez.yok.gov.tr. Funding This work was supported by Baskent University Research Fund. No conflict of interest was declared.
-
Osseous outgrowth on the buccal maxilla associated with piezosurgery-assisted en-masse retraction: A case series.
Korean journal of orthodontics, 2017Co-Authors: Nilüfer İrem Tunçer, Ayça Arman-Özçırpıcı, Bahar Füsun Oduncuoğlu, And Alpdoğan KantarcıAbstract:Piezoelectric surgery is a novel surgical approach used in orthodontic treatment for Rapid Tooth Movement. This paper presents a case series wherein osseous outgrowths were observed in response to piezosurgery-assisted en-masse retraction. Sixteen patients requiring upper premolar extractions were treated with miniscrew-supported en-masse retraction and received minimally invasive decortication via piezosurgery. Computed tomography (CT) of the maxillary anterior region was performed to investigate the nature of the outgrowths. In 8 of the 16 patients, hemispheric or disc-shaped osseous outgrowths were observed on the sites where piezosurgery was performed during retraction. CT images revealed that these outgrowths were alveolar bone. This case series presents a previously unreported osseous response to piezosurgery-assisted Tooth Movement during orthodontic treatment. The response is mostly transient and is observed in 50% of the treated patients, suggesting a bone turnover that can be assessed clinically and radiographically.
Xiaofang Zhu - One of the best experts on this subject based on the ideXlab platform.
-
6 shogaol promotes bone resorption and accelerates orthodontic Tooth Movement through the jnk nfatc1 signaling axis
Journal of Bone and Mineral Metabolism, 2021Co-Authors: Xiaofang Zhu, Hao Yuan, Ouyang Ningjuan, Carroll Ann Trotman, Thomas E Van Dyke, Jake Jinkun Chen, Guofang ShenAbstract:Corticotomy is widely used in clinical practice to accelerate Tooth Movement and shorten the duration of orthodontic treatment. It is effective, but an invasive surgery is needed to induce alveolar bone osteopenia that enable Rapid Tooth Movement. In this study, we discovered the potential of 6-shogaol as a more patient-friendly non-invasive alternative to induce transient osteopenia and accelerate Tooth Movement. The effects of 6-shogaol on the bone marrow macrophages (BMM) proliferation and osteoclast differentiation, and bone resorption were determined in vitro. Sprague–Dawley rats were distributed into three groups: CON, IPinj or Localinj and euthanized at day 28. Micro-CT, histology, immunohistological, and TUNEL analysis were performed to evaluate the Tooth Movement acceleration effect of 6-shogaol. In vitro, 6-shogaol promotes osteoclast differentiation and functional demineralization of alveolar bone. RANKL-induced mRNA expression of osteoclastic-specific genes was significantly higher in the presence of 6-shogaol. A dose-dependent increase in the area of TRAP-positive cells was observed with 6-shogaol treatment. F-actin ring formation and increased bone resorption confirmed that osteoclasts treated with 6-shogaol were mature and functional. 6-shogaol stimulated JNK activation and NFATc1 expression during osteoclast differentiation. In vivo, 6-shogaol promotes alveolar bone transient osteopenia and accelerates orthodontic Tooth Movement. Alveolar bone mass was reduced, more osteoclasts were observed in bone resorption lacunae on the compression side, and the expression of RANKL and sclerostin were higher than the control group. In conclusion, our results suggest that 6-shogoal accelerates Tooth Movement by inducing osteopenia by a mechanism similar to surgically induced bone injury.
Bahar Füsun Oduncuoğlu - One of the best experts on this subject based on the ideXlab platform.
-
efficiency of piezosurgery technique in miniscrew supported en masse retraction a single centre randomized controlled trial
European Journal of Ophthalmology, 2017Co-Authors: Nilüfer İrem Tunçer, Bahar Füsun Oduncuoğlu, Ayca Armanozcirpici, Julide Sedef Gocmen, Alpdogan KantarciAbstract:Background Piezoelectric surgery is a newly introduced technique for Rapid Tooth Movement. However, the efficiency of this technique has not been investigated on en-masse retraction cases yet. Objective To investigate the efficiency of piezosurgery technique in accelerating miniscrew supported en-masse retraction and study the biological tissue response. In addition, to show if this technique induces a difference in dental, skeletal and soft tissue changes on lateral cephalograms, and in canine and molar rotations, besides intercanine and intermolar widths on dental casts. Design, setting, participants We conducted a randomized, single-centred, parallel-group, controlled trial, requiring upper right and left first premolar extractions on 30 patients above the minimum age of 14 years at the beginning of retraction. Interventions Piezosurgery-assisted versus conventional en-masse retraction anchored from miniscrews placed between second premolars and first molars, bilaterally. Outcomes The main outcome was the en-masse retraction rate. Secondary outcomes were gingival crevicular fluid (GCF) volume and GCF content of receptor activator of nuclear factor κβ ligand (RANKL), changes regarding cephalometric and dental cast variables, and miniscrew success rates. Randomization Accomplished with opaque, sealed envelopes. Blinding Applicable for data assessment only. Recruitment Commenced in February 2013 and ended in October 2014. Results Thirty-one patients were included in the study and divided into 2 groups of piezosurgery (n = 16) and control (n = 15). After 9.3 months of follow-up, no statistically significant difference was observed between groups for neither retraction rates (P = 0.958) nor GCF parameters (P > 0.05). Changes in lateral cephalometric and dental cast variables, and miniscrew success rates did not show significant differences either. Conclusion Based on the results of this study, piezosurgery technique was found to be ineffective in accelerating en-masse retraction, and promoting a difference in the studied GCF parameters, skeletal and dental variables. Registration The trial was not registered. Protocol The full protocol of this PhD thesis study can be accessed from tez.yok.gov.tr. Funding This work was supported by Baskent University Research Fund. No conflict of interest was declared.
-
Osseous outgrowth on the buccal maxilla associated with piezosurgery-assisted en-masse retraction: A case series.
Korean journal of orthodontics, 2017Co-Authors: Nilüfer İrem Tunçer, Ayça Arman-Özçırpıcı, Bahar Füsun Oduncuoğlu, And Alpdoğan KantarcıAbstract:Piezoelectric surgery is a novel surgical approach used in orthodontic treatment for Rapid Tooth Movement. This paper presents a case series wherein osseous outgrowths were observed in response to piezosurgery-assisted en-masse retraction. Sixteen patients requiring upper premolar extractions were treated with miniscrew-supported en-masse retraction and received minimally invasive decortication via piezosurgery. Computed tomography (CT) of the maxillary anterior region was performed to investigate the nature of the outgrowths. In 8 of the 16 patients, hemispheric or disc-shaped osseous outgrowths were observed on the sites where piezosurgery was performed during retraction. CT images revealed that these outgrowths were alveolar bone. This case series presents a previously unreported osseous response to piezosurgery-assisted Tooth Movement during orthodontic treatment. The response is mostly transient and is observed in 50% of the treated patients, suggesting a bone turnover that can be assessed clinically and radiographically.
Kantarci Alpdogan - One of the best experts on this subject based on the ideXlab platform.
-
Efficiency of piezosurgery technique in miniscrew supported en-masse retraction: a single-centre, randomized controlled trial
'Oxford University Press (OUP)', 2017Co-Authors: Tuncer, Nilufer Irem, Arman-ozcirpici Ayca, Oduncuoglu, Bahar Fusun, Gocmen, Julide Sedef, Kantarci AlpdoganAbstract:Piezoelectric surgery is a newly introduced technique for Rapid Tooth Movement. However, the efficiency of this technique has not been investigated on en-masse retraction cases yet. To investigate the efficiency of piezosurgery technique in accelerating miniscrew supported en-masse retraction and study the biological tissue response. In addition, to show if this technique induces a difference in dental, skeletal and soft tissue changes on lateral cephalograms, and in canine and molar rotations, besides intercanine and intermolar widths on dental casts. We conducted a randomized, single-centred, parallel-group, controlled trial, requiring upper right and left first premolar extractions on 30 patients above the minimum age of 14 years at the beginning of retraction. Piezosurgery-assisted versus conventional en-masse retraction anchored from miniscrews placed between second premolars and first molars, bilaterally. The main outcome was the en-masse retraction rate. Secondary outcomes were gingival crevicular fluid (GCF) volume and GCF content of receptor activator of nuclear factor kappa beta ligand (RANKL), changes regarding cephalometric and dental cast variables, and miniscrew success rates. Accomplished with opaque, sealed envelopes. Applicable for data assessment only. Commenced in February 2013 and ended in October 2014. Thirty-one patients were included in the study and divided into 2 groups of piezosurgery (n = 16) and control (n = 15). After 9.3 months of follow-up, no statistically significant difference was observed between groups for neither retraction rates (P = 0.958) nor GCF parameters (P > 0.05). Changes in lateral cephalometric and dental cast variables, and miniscrew success rates did not show significant differences either. Based on the results of this study, piezosurgery technique was found to be ineffective in accelerating en-masse retraction, and promoting a difference in the studied GCF parameters, skeletal and dental variables. The trial was not registered. The full protocol of this PhD thesis study can be accessed from tez.yok.gov.tr
Alpdogan Kantarci - One of the best experts on this subject based on the ideXlab platform.
-
efficiency of piezosurgery technique in miniscrew supported en masse retraction a single centre randomized controlled trial
European Journal of Ophthalmology, 2017Co-Authors: Nilüfer İrem Tunçer, Bahar Füsun Oduncuoğlu, Ayca Armanozcirpici, Julide Sedef Gocmen, Alpdogan KantarciAbstract:Background Piezoelectric surgery is a newly introduced technique for Rapid Tooth Movement. However, the efficiency of this technique has not been investigated on en-masse retraction cases yet. Objective To investigate the efficiency of piezosurgery technique in accelerating miniscrew supported en-masse retraction and study the biological tissue response. In addition, to show if this technique induces a difference in dental, skeletal and soft tissue changes on lateral cephalograms, and in canine and molar rotations, besides intercanine and intermolar widths on dental casts. Design, setting, participants We conducted a randomized, single-centred, parallel-group, controlled trial, requiring upper right and left first premolar extractions on 30 patients above the minimum age of 14 years at the beginning of retraction. Interventions Piezosurgery-assisted versus conventional en-masse retraction anchored from miniscrews placed between second premolars and first molars, bilaterally. Outcomes The main outcome was the en-masse retraction rate. Secondary outcomes were gingival crevicular fluid (GCF) volume and GCF content of receptor activator of nuclear factor κβ ligand (RANKL), changes regarding cephalometric and dental cast variables, and miniscrew success rates. Randomization Accomplished with opaque, sealed envelopes. Blinding Applicable for data assessment only. Recruitment Commenced in February 2013 and ended in October 2014. Results Thirty-one patients were included in the study and divided into 2 groups of piezosurgery (n = 16) and control (n = 15). After 9.3 months of follow-up, no statistically significant difference was observed between groups for neither retraction rates (P = 0.958) nor GCF parameters (P > 0.05). Changes in lateral cephalometric and dental cast variables, and miniscrew success rates did not show significant differences either. Conclusion Based on the results of this study, piezosurgery technique was found to be ineffective in accelerating en-masse retraction, and promoting a difference in the studied GCF parameters, skeletal and dental variables. Registration The trial was not registered. Protocol The full protocol of this PhD thesis study can be accessed from tez.yok.gov.tr. Funding This work was supported by Baskent University Research Fund. No conflict of interest was declared.
