The Experts below are selected from a list of 225 Experts worldwide ranked by ideXlab platform

Seung Goun Hong - One of the best experts on this subject based on the ideXlab platform.

  • tranexamic acid induced acute Renal Cortical Necrosis in post endoscopic papillectomy bleeding
    Clinical Endoscopy, 2017
    Co-Authors: Doo Hyun Ko, Ja Joong Gu, Baek Hyun Yoon, Ji Hong Oh, Seung Goun Hong
    Abstract:

    : Acute Renal failure can be the result of acute Renal Cortical Necrosis (RCN), which commonly occurs from complications occurring during pregnancy. RCN is rarely caused by medications, although tranexamic acid, which is used in patients with acute bleeding for its antifibrinolytic effects, reportedly causes acute RCN in rare cases. An 82-year-old woman experienced gastrointestinal bleeding after endoscopic papillectomy of an ampullary adenoma. The bleeding was controlled with tranexamic acid administration; however, 4 days later, her urine volume decreased and she developed pulmonary edema and dyspnea. Serum creatinine levels increased from 0.8 to 3.9 mg/dL and dialysis was performed. Abdominal pelvic computed tomography with contrast enhancement revealed bilateral RCN with no Renal cortex enhancement. Renal dysfunction and oliguria persisted and hemodialysis was continued. Clinicians must be aware that acute RCN can occur after tranexamic acid administration to control bleeding.

Veronique Baudouin - One of the best experts on this subject based on the ideXlab platform.

  • acute Renal Cortical Necrosis due to acquired antiprotein s antibodies
    Pediatric Nephrology, 2009
    Co-Authors: Anis Larakeb, Solene Evrard, Ferielle Louillet, Theresa Kwon, Hadji Djaffar, Brigitte Llanas, Georges Deschenes, Mariefrancoise Hurtaudroux, Veronique Baudouin
    Abstract:

    Although varicella is a common disease of childhood, Renal complications are quite rare. We report here the interesting case of a-22 month-old boy exhibiting Renal Cortical Necrosis related to an acquired protein S deficiency following varicella. Ten days after the vesicle eruption appearance, he presented with ecchymosed heels, oligoanuric kidney failure, anemia [hemoglobin (Hb) 78 g/L], schizocytosis (2.5%), but normal platelet count. Kidney sonography and magnetic resonance imaging evoked Renal Cortical Necrosis. All together, these features suggested acquired protein S deficiency secondary to varicella. Strikingly, it was confirmed by a dramatic decrease in protein S plasma activity and a huge increase in immunoglobulin (Ig)G antibodies against protein S in the plasma. Anticoagulation therapy in addition with plasmapheresis and steroid pulses allowed a dramatic decrease in the antibodies against protein S and recovery of normal protein S activity. Undelayed diagnosis and treatment did not avoid kidney insufficiency but prevented life-threatening complications. In the light of this case report, protein S deficiency due to antibody inhibition should be carefully monitored anytime in the context of varicella when kidney insufficiency or Necrosis occurs.

Joon Sung Park - One of the best experts on this subject based on the ideXlab platform.

  • bilateral Renal Cortical Necrosis following binge drinking
    Alcohol and Alcoholism, 2012
    Co-Authors: Yeon Soon Jung, Ho Sik Shin, Kiseok Jang, Moon Hyang Park, Joon Sung Park, Chong Myung Kang
    Abstract:

    Renal Cortical Necrosis (RCN) is a rare cause of acute kidney injury secondary to ischemic Necrosis of the Renal cortex. Acute tubular Necrosis after binge drinking is usually attributed to volume depletion, idiosyncratic reaction to alcohol, rhabdomyolysis or a combination with non-steroidal anti-inflammatory drugs. Binge drinking itself as a cause of RCN has not yet been reported. We report a case of a 25-year-old Asian male who developed bilateral RCN following binge drinking.

  • clinical aspects bilateral Renal Cortical Necrosis following binge drinking
    2012
    Co-Authors: Yeon Soon Jung, Ho Sik Shin, Kiseok Jang, Moon Hyang Park, Joon Sung Park, Chong Myung Kang
    Abstract:

    Renal Cortical Necrosis (RCN) is a rare cause of acute kidney injury secondary to ischemic Necrosis of the Renal cortex. Acute tubular Necrosis after binge drinking is usually attributed to volume depletion, idiosyncratic reaction to alcohol, rhabdomyoly- sis or a combination with non-steroidal anti-inflammatory drugs. Binge drinking itself as a cause of RCN has not yet been reported. We report a case of a 25-year-old Asian male who developed bilateral RCN following binge drinking.

  • bilateral acute Renal Cortical Necrosis in sle associated antiphospholipid syndrome
    American Journal of Kidney Diseases, 2011
    Co-Authors: Chong Myung Kang, Joon Sung Park
    Abstract:

    Acute Renal Cortical Necrosis (ARCN) is a rare cause of acute kidney injury and is characterized by the entire destruction of the Renal cortex. We describe a 16-year-old girl with unremarkable personal or family history who presented with acute anuria and dyspnea. Evaluation showed acute kidney injury associated with metabolic acidosis, hyperkalemia, anemia, thrombocytopenia, hematuria, and proteinuria. Serologic tests showed systemic lupus erythematosus–related antiphospholipid syndrome with low serum complement C3 levels, positive anti–double-stranded DNA antibody, positive antiphospholipid antibody, and positive antinuclear antibody. Contrast-enhanced abdominal computed tomography confirmed the presence of ARCN by showing contrasted medulla and a thin layer of subcapsular cortex, but without bilateral enhancement of the Renal cortex. This case shows the role of imaging in patients with bilateral ARCN in systemic lupus erythematosus–related antiphospholipid syndrome.

Takahiro Ueda - One of the best experts on this subject based on the ideXlab platform.

  • unilateral Renal Cortical Necrosis with contralateral hydronephrosis after surgery for uterus carcinoma
    Clinical and Experimental Nephrology, 2003
    Co-Authors: Seiji Hashimoto, Kouichi Shiroshita, Tetsuo Sakurai, Akio Takada, Tetsuya Kawata, Takao Koike, Hidetoshi Sato, Takahiro Ueda
    Abstract:

    Renal Cortical Necrosis (RCN) represents a rare cause of acute Renal failure that is characterized by Necrosis of the Renal cortex with sparing of the medulla. Most previous RCN cases reported have been bilateral and have occurred in pregnancy. Unilateral RCN is a quite rare disorder. Here, we report a case of unilateral RCN with contralateral hydronephrosis after surgery for uterus carcinoma. In this patient it seems that hydronephrosis had been present before RCN occurrence. It is suggested that ureteric obstruction protects against RCN development.

Doo Hyun Ko - One of the best experts on this subject based on the ideXlab platform.

  • tranexamic acid induced acute Renal Cortical Necrosis in post endoscopic papillectomy bleeding
    Clinical Endoscopy, 2017
    Co-Authors: Doo Hyun Ko, Ja Joong Gu, Baek Hyun Yoon, Ji Hong Oh, Seung Goun Hong
    Abstract:

    : Acute Renal failure can be the result of acute Renal Cortical Necrosis (RCN), which commonly occurs from complications occurring during pregnancy. RCN is rarely caused by medications, although tranexamic acid, which is used in patients with acute bleeding for its antifibrinolytic effects, reportedly causes acute RCN in rare cases. An 82-year-old woman experienced gastrointestinal bleeding after endoscopic papillectomy of an ampullary adenoma. The bleeding was controlled with tranexamic acid administration; however, 4 days later, her urine volume decreased and she developed pulmonary edema and dyspnea. Serum creatinine levels increased from 0.8 to 3.9 mg/dL and dialysis was performed. Abdominal pelvic computed tomography with contrast enhancement revealed bilateral RCN with no Renal cortex enhancement. Renal dysfunction and oliguria persisted and hemodialysis was continued. Clinicians must be aware that acute RCN can occur after tranexamic acid administration to control bleeding.