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Marie-roberte Guichaoua - One of the best experts on this subject based on the ideXlab platform.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian journal of andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3–6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (≥40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian Journal of Andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3-6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (>= 40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period. Asian Journal of Andrology (2012) 14, 584-590; doi:10.1038/aja.2011.173; published online 23 April 2012

Philippe Durand - One of the best experts on this subject based on the ideXlab platform.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian journal of andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3–6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (≥40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian Journal of Andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3-6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (>= 40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period. Asian Journal of Andrology (2012) 14, 584-590; doi:10.1038/aja.2011.173; published online 23 April 2012

  • Quantitation by image analysis of global DNA methylation in human spermatozoa and its prognostic value in in vitro fertilization: a preliminary study
    Fertility and sterility, 2003
    Co-Authors: Mehdi Benchaib, Mounir Ajina, Jacqueline Lornage, Alain Niveleau, Philippe Durand, Jean François Guerin
    Abstract:

    Abstract Objective: To determine the relationship between sperm DNA methylation level and sperm characteristics and pregnancy rates. Design: Prospective study. Quantitation by image analysis of DNA methylation in sperm nucleus. Setting: Department of Reproduction Biology, Edouard Herriot Hospital, Lyon, France. Patient(s): Infertile couples undergoing IVF-ET. Intervention(s): The immunostaining of 5 methyl-cytosine was performed on the spare sperm suspension that was used for an assisted Reproduction technology procedure. Main outcome measure(s): Sperm characteristics according to World Health Organization criteria, sperm motility parameters with computer-assisted semen analysis, sperm DNA methylation level, and heterogeneity index (HI). Result(s): Sperm DNA methylation level and HI are correlated with sperm DNA characteristics. HI is negatively correlated with fertilization rate; sperm DNA methylation level is correlated with pregnancy rate. Conclusion(s): The DNA methylation level in human spermatozoa could be a new approach to evaluating the ability of spermatozoa to fertilize and lead to normal embryo development.

C. Geoffroy-siraudin - One of the best experts on this subject based on the ideXlab platform.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian journal of andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3–6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (≥40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian Journal of Andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3-6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (>= 40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period. Asian Journal of Andrology (2012) 14, 584-590; doi:10.1038/aja.2011.173; published online 23 April 2012

Vincent Achard - One of the best experts on this subject based on the ideXlab platform.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian journal of andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3–6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (≥40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian Journal of Andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3-6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (>= 40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period. Asian Journal of Andrology (2012) 14, 584-590; doi:10.1038/aja.2011.173; published online 23 April 2012

Anderson Loundou - One of the best experts on this subject based on the ideXlab platform.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian journal of andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3–6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (≥40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period.

  • Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France
    Asian Journal of Andrology, 2012
    Co-Authors: C. Geoffroy-siraudin, Philippe Durand, Anderson Loundou, Fanny Romain, Vincent Achard, Blandine Courbiere, Marie-hélène Perrard, Marie-roberte Guichaoua
    Abstract:

    Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille (France) between 1988 and 2007. After 3-6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration (>= 40 million per ejaculate). The whole population demonstrated declining trends in sperm concentration (1.5% per year), total sperm count (1.6% per year), total motility (0.4% per year), rapid motility (5.5% per year) and normal morphology (2.2% per year). In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the quality of semen decreased in this population over the study period. Asian Journal of Andrology (2012) 14, 584-590; doi:10.1038/aja.2011.173; published online 23 April 2012