The Experts below are selected from a list of 3285 Experts worldwide ranked by ideXlab platform

Daniel Tomé - One of the best experts on this subject based on the ideXlab platform.

  • Impact of the diet on net endogenous acid production and acid-base balance.
    Clinical nutrition (Edinburgh Scotland), 2012
    Co-Authors: Nathalie Poupin, Juliane Calvez, Camille Lassale, C Chesneau, Daniel Tomé
    Abstract:

    Summary Net acid production, which is composed of volatile acids (15,000 mEq/day) and metabolic acids (70–100 mEq/day) is relatively small compared to whole-body H + turnover (150,000 mEq/day). Metabolic acids are ingested from the diet or produced as intermediary or end products of endogenous metabolism. The three commonly reported sources of net acid production are the metabolism of sulphur amino acids, the metabolism or ingestion of organic acids, and the metabolism of phosphate esters or dietary phosphoproteins. Net base production occurs mainly as a result of absorption of organic anions from the diet. To maintain acid-base balance, ingested and endogenously produced acids are neutralized within the body by buffer systems or eliminated from the body through the Respiratory (Excretion of volatile acid in the form of CO 2 ) and urinary (Excretion of fixed acids and remaining H + ) pathways. Because of the many reactions involved in the acid-base balance, the direct determination of acid production is complex and is usually estimated through direct or indirect measurements of acid Excretion. However, indirect approaches, which assess the acid-forming potential of the ingested diet based on its composition, do not take all the acid-producing reactions into account. Direct measurements therefore seem more reliable. Nevertheless, acid Excretion does not truly provide information on the way acidity is dealt with in the plasma and this measurement should be interpreted with caution when assessing acid-base imbalance.

  • Impact of the diet on net endogenous acid production and acid–base balance
    Clinical Nutrition, 2012
    Co-Authors: Nathalie Poupin, Juliane Calvez, Camille Lassale, C Chesneau, Daniel Tomé
    Abstract:

    Net acid production, which is composed of volatile acids (15,000 mEq/day) and metabolic acids (70-100 mEq/day) is relatively small compared to whole-body H+ turnover (150,000 mEq/day). Metabolic acids are ingested from the diet or produced as intermediary or end products of endogenous metabolism. The three commonly reported sources of net acid production are the metabolism of sulphur amino acids, the metabolism or ingestion of organic acids, and the metabolism of phosphate esters or dietary phosphoproteins. Net base production occurs mainly as a result of absorption of organic anions from the diet. To maintain acid-base balance, ingested and endogenously produced acids are neutralized within the body by buffer systems or eliminated from the body through the Respiratory (Excretion of volatile acid in the form of CO2) and urinary (Excretion of fixed acids and remaining H+) pathways. Because of the many reactions involved in the acid-base balance, the direct determination of acid production is complex and is usually estimated through direct or indirect measurements of acid Excretion. However, indirect approaches, which assess the acid-forming potential of the ingested diet based on its composition, do not take all the acid-producing reactions into account. Direct measurements therefore seem more reliable. Nevertheless, acid Excretion does not truly provide information on the way acidity is dealt with in the plasma and this measurement should be interpreted with caution when assessing acid-base imbalance. (C) 2012 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Nathalie Poupin - One of the best experts on this subject based on the ideXlab platform.

  • Impact of the diet on net endogenous acid production and acid-base balance.
    Clinical nutrition (Edinburgh Scotland), 2012
    Co-Authors: Nathalie Poupin, Juliane Calvez, Camille Lassale, C Chesneau, Daniel Tomé
    Abstract:

    Summary Net acid production, which is composed of volatile acids (15,000 mEq/day) and metabolic acids (70–100 mEq/day) is relatively small compared to whole-body H + turnover (150,000 mEq/day). Metabolic acids are ingested from the diet or produced as intermediary or end products of endogenous metabolism. The three commonly reported sources of net acid production are the metabolism of sulphur amino acids, the metabolism or ingestion of organic acids, and the metabolism of phosphate esters or dietary phosphoproteins. Net base production occurs mainly as a result of absorption of organic anions from the diet. To maintain acid-base balance, ingested and endogenously produced acids are neutralized within the body by buffer systems or eliminated from the body through the Respiratory (Excretion of volatile acid in the form of CO 2 ) and urinary (Excretion of fixed acids and remaining H + ) pathways. Because of the many reactions involved in the acid-base balance, the direct determination of acid production is complex and is usually estimated through direct or indirect measurements of acid Excretion. However, indirect approaches, which assess the acid-forming potential of the ingested diet based on its composition, do not take all the acid-producing reactions into account. Direct measurements therefore seem more reliable. Nevertheless, acid Excretion does not truly provide information on the way acidity is dealt with in the plasma and this measurement should be interpreted with caution when assessing acid-base imbalance.

  • Impact of the diet on net endogenous acid production and acid–base balance
    Clinical Nutrition, 2012
    Co-Authors: Nathalie Poupin, Juliane Calvez, Camille Lassale, C Chesneau, Daniel Tomé
    Abstract:

    Net acid production, which is composed of volatile acids (15,000 mEq/day) and metabolic acids (70-100 mEq/day) is relatively small compared to whole-body H+ turnover (150,000 mEq/day). Metabolic acids are ingested from the diet or produced as intermediary or end products of endogenous metabolism. The three commonly reported sources of net acid production are the metabolism of sulphur amino acids, the metabolism or ingestion of organic acids, and the metabolism of phosphate esters or dietary phosphoproteins. Net base production occurs mainly as a result of absorption of organic anions from the diet. To maintain acid-base balance, ingested and endogenously produced acids are neutralized within the body by buffer systems or eliminated from the body through the Respiratory (Excretion of volatile acid in the form of CO2) and urinary (Excretion of fixed acids and remaining H+) pathways. Because of the many reactions involved in the acid-base balance, the direct determination of acid production is complex and is usually estimated through direct or indirect measurements of acid Excretion. However, indirect approaches, which assess the acid-forming potential of the ingested diet based on its composition, do not take all the acid-producing reactions into account. Direct measurements therefore seem more reliable. Nevertheless, acid Excretion does not truly provide information on the way acidity is dealt with in the plasma and this measurement should be interpreted with caution when assessing acid-base imbalance. (C) 2012 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

W.m. Deen - One of the best experts on this subject based on the ideXlab platform.

  • Metabolism and Excretion of methylamines in rats.
    Toxicology and applied pharmacology, 1994
    Co-Authors: J.l. Smith, John S. Wishnok, W.m. Deen
    Abstract:

    Experiments were performed with rats to examine the sources and disposition of dimethylamine (DMA), trimethylamine (TMA), and trimethylamine N-oxide (TMAO), all potential substrates for in vivo nitrosation to form N-nitrosodimethylamine (NDMA), a potent carcinogen. When bolus doses of [14C]DMA or [14C]TMA were given ip, recovery of radioactivity in the urine was essentially complete, and Respiratory Excretion, fecal Excretion, and accumulation in tissues of these amines or their metabolites were negligible. Urine analysis following doses of stable isotopes showed that DMA was not converted to TMA or TMAO. Varying amounts of TMA were oxidized to TMAO, the fraction oxidized decreasing at higher doses of TMA. Ingestion and Excretion of naturally occurring methylamines were monitored over a 5-day period in separate groups of normal and germ-free rats. The results of these metabolic balance studies indicate that there is net synthesis of DMA by gut bacteria and net consumption of TMAO by endogenous processes. The net intake or Excretion of TMA and TMAO observed in normal and germ-free rats is consistent with bacterial synthesis of TMA followed by its almost complete oxidation to TMAO. Blood concentrations of DMA and TMA were measured in rats for 8 hr following

Danielle Thouvenot - One of the best experts on this subject based on the ideXlab platform.

  • Detection of measles vaccine in the throat of a vaccinated child.
    Vaccine, 2002
    Co-Authors: Florence Morfin, Anne Beguin, Bruno Lina, Danielle Thouvenot
    Abstract:

    Measles vaccine is widely used, most often in association with mumps and rubella vaccines. We report here the case of a child presenting with fever 8 days after vaccination with a measles–mumps–rubella vaccine. Measles virus was isolated in a throat swab taken 4 days after fever onset. This virus was then further genetically characterised as a vaccine-type virus. Fever occurring subsequent to measles vaccination is related to the replication of the live attenuated vaccine virus. In the case presented here, the vaccine virus was isolated in the throat, showing that subcutaneous injection of an attenuated measles strain can result in Respiratory Excretion of this virus.

C Chesneau - One of the best experts on this subject based on the ideXlab platform.

  • Impact of the diet on net endogenous acid production and acid-base balance.
    Clinical nutrition (Edinburgh Scotland), 2012
    Co-Authors: Nathalie Poupin, Juliane Calvez, Camille Lassale, C Chesneau, Daniel Tomé
    Abstract:

    Summary Net acid production, which is composed of volatile acids (15,000 mEq/day) and metabolic acids (70–100 mEq/day) is relatively small compared to whole-body H + turnover (150,000 mEq/day). Metabolic acids are ingested from the diet or produced as intermediary or end products of endogenous metabolism. The three commonly reported sources of net acid production are the metabolism of sulphur amino acids, the metabolism or ingestion of organic acids, and the metabolism of phosphate esters or dietary phosphoproteins. Net base production occurs mainly as a result of absorption of organic anions from the diet. To maintain acid-base balance, ingested and endogenously produced acids are neutralized within the body by buffer systems or eliminated from the body through the Respiratory (Excretion of volatile acid in the form of CO 2 ) and urinary (Excretion of fixed acids and remaining H + ) pathways. Because of the many reactions involved in the acid-base balance, the direct determination of acid production is complex and is usually estimated through direct or indirect measurements of acid Excretion. However, indirect approaches, which assess the acid-forming potential of the ingested diet based on its composition, do not take all the acid-producing reactions into account. Direct measurements therefore seem more reliable. Nevertheless, acid Excretion does not truly provide information on the way acidity is dealt with in the plasma and this measurement should be interpreted with caution when assessing acid-base imbalance.

  • Impact of the diet on net endogenous acid production and acid–base balance
    Clinical Nutrition, 2012
    Co-Authors: Nathalie Poupin, Juliane Calvez, Camille Lassale, C Chesneau, Daniel Tomé
    Abstract:

    Net acid production, which is composed of volatile acids (15,000 mEq/day) and metabolic acids (70-100 mEq/day) is relatively small compared to whole-body H+ turnover (150,000 mEq/day). Metabolic acids are ingested from the diet or produced as intermediary or end products of endogenous metabolism. The three commonly reported sources of net acid production are the metabolism of sulphur amino acids, the metabolism or ingestion of organic acids, and the metabolism of phosphate esters or dietary phosphoproteins. Net base production occurs mainly as a result of absorption of organic anions from the diet. To maintain acid-base balance, ingested and endogenously produced acids are neutralized within the body by buffer systems or eliminated from the body through the Respiratory (Excretion of volatile acid in the form of CO2) and urinary (Excretion of fixed acids and remaining H+) pathways. Because of the many reactions involved in the acid-base balance, the direct determination of acid production is complex and is usually estimated through direct or indirect measurements of acid Excretion. However, indirect approaches, which assess the acid-forming potential of the ingested diet based on its composition, do not take all the acid-producing reactions into account. Direct measurements therefore seem more reliable. Nevertheless, acid Excretion does not truly provide information on the way acidity is dealt with in the plasma and this measurement should be interpreted with caution when assessing acid-base imbalance. (C) 2012 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.