Saccule

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Mario Gagliardi - One of the best experts on this subject based on the ideXlab platform.

  • preservation of vestibular evoked myogenic potentials with modified translabyrinthine approach
    Archives of Otolaryngology-head & Neck Surgery, 2007
    Co-Authors: Giuseppe Magliulo, Donato Parrotto, Giuseppe Cuiuli, Francesca Romana Alla, Mario Gagliardi
    Abstract:

    estibular evoked myogenic potentials (VEMPs) represent a relatively recent subject Vestibular evoked myogenic potentials (VEMPs) represent a relatively recent subject of investigation in regard to diagnosing specific vestibular disorders. Numerous experimental animal models 1-3 and clinical studies 4-9 suggest that VEMPs are a vestibularcolic reflex, the afferent branch of which originates in the acoustic cells of the Saccule, conducting signals through the inferior vestibular nerve. These studies have proposed hypotheses based on the possibility of VEMPs originating in the Saccule but have provided no definitive proof to that effect.

Joseph A Sisneros - One of the best experts on this subject based on the ideXlab platform.

  • Auditory saccular sensitivity of the vocal Lusitanian toadfish: low frequency tuning allows acoustic communication throughout the year
    Journal of Comparative Physiology A-neuroethology Sensory Neural and Behavioral Physiology, 2011
    Co-Authors: Raquel O. Vasconcelos, Joseph A Sisneros, M. Clara P. Amorim, Paulo J. Fonseca
    Abstract:

    A novel form of auditory plasticity for enhanced detection of social signals was described in a teleost fish, Porichthys notatus (Batrachoididae, Porichthyinae). The seasonal onset of male calling coincides with inshore migration from deep waters by both sexes and increased female sensitivity to dominant frequencies of male calls. The closely related Lusitanian toadfish, Halobatrachus didactylus, (Batrachoididae, Halophryninae) also breeds seasonally and relies on acoustic communication to find mates but, instead, both sexes stay in estuaries and show vocal activity throughout the year. We investigated whether the sensitivity of the inner ear Saccule of H. didactylus is seasonally plastic and sexually dimorphic. We recorded evoked potentials from populations of saccular hair cells from non-reproductive and reproductive males and females in response to 15–945 Hz tones. Saccular hair cells were most sensitive at 15–205 Hz (thresholds between 111 and 118 dB re. 1 μPa). Both sexes showed identical hearing sensitivity and no differences were found across seasons. The Saccule was well suited to detect conspecific vocalizations and low frequencies that overlapped with lateral line sensitivity. We showed that the Saccule in H. didactylus has major importance in acoustic communication throughout the year and that significant sensory differences may exist between the two batrachoidid subfamilies.

  • directional and frequency saccular sensitivity of the little skate raja erinacea
    Journal of the Acoustical Society of America, 2011
    Co-Authors: Joseph A Sisneros
    Abstract:

    Although a number of previous behavioral studies have demonstrated that elasmobranch fishes can detect and are attracted to low frequency sounds, few physiological studies have characterized the auditory response properties of the elasmobranch inner ear to such low frequency sounds. In this study, we examined the directional and frequency responses of the inner ear Saccule in the little skate, Raja erinacea to low frequency stimuli. Evoked microphonic potentials were recorded from the middle region of the Saccule while sound was generated using a shaker table designed to mimic the particle motion vector component of sound. 8 test frequencies (50, 64, 84, 100, 140, 185, 243, and 303 Hz) and 11 directions were used to characterize the displacement sensitivity, frequency response and directional response properties of the skate Saccule. Saccular potentials were evoked and measured at twice the stimulus frequency in vivo using a wave analyzer while stimuli were generated via the shaker table system. The right...

  • auditory saccular potentials of the little skate raja erinacea
    Journal of the Acoustical Society of America, 2009
    Co-Authors: Joseph A Sisneros
    Abstract:

    Previous behavioral studies have shown that elasmobranch fishes can be attracted to low‐frequency sound sources (< 80 Hz) in their natural habitat, but relatively few studies have characterized the auditory response properties of the elasmobranch inner ear to low‐frequency sounds. Here, we examine the response properties of evoked saccular potentials from the skate inner ear to determine the auditory threshold sensitivity and frequency response of saccular hair cells to low‐frequency stimuli. Saccular potentials were recorded from the medial region of the Saccule while sound was generated using a shaker table designed to mimic the particle motion component of sound. Four test frequencies (50, 64, 84, and 100 Hz) and 11 directions were used to characterize the displacement sensitivity, frequency response, and directional response properties of the skate Saccule. Saccular potentials were evoked and measured at twice the stimulus frequency in vivo using a wave analyzer, while stimuli were generated via the s...

  • Saccular potentials of the vocal plainfin midshipman fish, Porichthys notatus
    Journal of Comparative Physiology A, 2007
    Co-Authors: Joseph A Sisneros
    Abstract:

    The plainfin midshipman fish, Porichthys notatus , is a vocal species of teleost fish that generates acoustic signals for intraspecific communication during social and reproductive behaviors. All adult morphs (females and males) produce single short duration grunts important for agonistic encounters, but only nesting males produce trains of grunts and growls in agonistic contexts and long duration multiharmonic advertisement calls to attract gravid females for spawning. The midshipman fish uses the Saccule as the main acoustic endorgan for hearing to detect and locate vocalizing conspecifics. Here, I examined the response properties of evoked potentials from the midshipman Saccule to determine the frequency response and auditory threshold sensitivity of saccular hair cells to behaviorally-relevant single tone stimuli. Saccular potentials were recorded from the rostral, medial and caudal regions of the Saccule while sound was presented by an underwater speaker. Saccular potentials of the midshipman, like other teleosts, were evoked greatest at a frequency that was twice the stimulus frequency. Results indicate that midshipman saccular hair cells of non-reproductive adults had a peak frequency sensitivity that ranged from 75 (lowest frequency tested) to 145 Hz and were best suited to detect the low frequency components (≤105 Hz) of midshipman vocalizations.

Zhengmin Wang - One of the best experts on this subject based on the ideXlab platform.

  • Three-dimensional morphological measurements of the utricle, Saccule and stapes footplate
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2006
    Co-Authors: Tianyu Zhang, Zhengmin Wang, Pei-dong Dai, You-zhou Xie, Ke-qiang Wang
    Abstract:

    Objective To determine the optimal drill area on the footplate with the 3D measurements of the stapes and the vestibular end organs. Methods Four temporal bones were extracted from the fresh cadavers and undecalcified polymer-embedded. After serially sectioning, image processing and the 3D precisely reconstruction, a local Cartesian coordinates was established in which the tympanic surface of the footplate was supposed to be XY plane and the Z coordinate axis passed through the central point of the footplate and was vertical to the XY plane. The configurations of the utricle and Saccule were delineated quantitatively, and then any distance between one point on the surface of the footplate and another point on the surface of the utricle or Saccule and its orientation can be measured. Results There was a "V" shaped deft between the utricle and the Saccule. The angle of the" V" shaped deft was 50.31 ± 19.90 (17.00 - 68.00) degrees. The apex of the deft directed anterosuperiorly and approached the footplate center, while beneath the posteroinferior part of the footplate was an open and deep area. The vertical distance from the center point of the footplate to the vestibular end organs was (2.20 ± 0.548)mm, the maximum of 3.0 mm and the minimum of 1.6 mm Conclusions The posterior and inferior quadrant of the footplate may be the optimal drill area for the fenestra. Key words: Saccule and utricle; Stapes; Imaging, three-dimensional reconstruction

  • modified stapes prosthesis to limit postoperative vertigo
    Otolaryngology-Head and Neck Surgery, 2005
    Co-Authors: Zhengmin Wang
    Abstract:

    Objective To investigate the anatomic relationship between utricle, Saccule, and stapes footplate, and adapt the stapes prosthesis tip to reduce postoperative vertigo. Study design Five temporal bones were serially sectioned and stained, and the distance from the inner lining of stapes footplate to Saccule and utricle, respectively, were measured. The Fisch prosthesis was modified with a slope of 45 degrees at its tip to adapt to the anatomic configuration of the vestibule. Fisch’s original piston or the modified piston was used in 174 ears (Group I) and 108 ears (Group II), randomly. Results There was no statistically significant difference in hearing improvement between the 2 groups (P > 0.5). However, postoperative vertigo was significantly reduced when the modified prosthesis was inserted (P Conclusions The modified piston improved the hearing to the level of the original piston, and the incidence of postoperative vertigo was significantly decreased. Significance A modified prosthesis is presented for a patient undergoing stapedotomy.

Giuseppe Magliulo - One of the best experts on this subject based on the ideXlab platform.

  • preservation of vestibular evoked myogenic potentials with modified translabyrinthine approach
    Archives of Otolaryngology-head & Neck Surgery, 2007
    Co-Authors: Giuseppe Magliulo, Donato Parrotto, Giuseppe Cuiuli, Francesca Romana Alla, Mario Gagliardi
    Abstract:

    estibular evoked myogenic potentials (VEMPs) represent a relatively recent subject Vestibular evoked myogenic potentials (VEMPs) represent a relatively recent subject of investigation in regard to diagnosing specific vestibular disorders. Numerous experimental animal models 1-3 and clinical studies 4-9 suggest that VEMPs are a vestibularcolic reflex, the afferent branch of which originates in the acoustic cells of the Saccule, conducting signals through the inferior vestibular nerve. These studies have proposed hypotheses based on the possibility of VEMPs originating in the Saccule but have provided no definitive proof to that effect.

Arnaud Attyé - One of the best experts on this subject based on the ideXlab platform.

  • Endolymph magnetic resonance imaging: Contribution of Saccule and utricle analysis in the management of patients with sensorineural ear disorders.
    European Annals of Otorhinolaryngology Head and Neck Diseases, 2020
    Co-Authors: Arnaud Attyé, Michael Eliezer
    Abstract:

    Abstract Endolymphatic hydrops features excess endolymph in the membranous labyrinth, and is a marker of Meniere's disease. Between the early 1980s and late 2000s, MRI in Meniere's disease aimed purely to rule out tumor or malformation as differential diagnoses for the pressure disorder. Progress in high-resolution MRI, however, now enables excess endolymph to be visualized in the membranous labyrinth, differentiating Saccule and utricle in Meniere's disease and in other clinical presentations such as cochleovestibular schwannoma. More recently, non-visibility of the Saccule was demonstrated in a subgroup of Meniere's disease patients, and utricle atelectasis in case of uni- or bilateral vestibular areflexia. Endolymph quantification remains highly controversial in terms of grading approach, but a simple semiology based on excess or deficient visualization of endolymph according to the compartment sheds light on the pathophysiological mechanisms of cochleovestibular disorder and may in future allow effective monitoring of medical and surgical treatment.

  • vestibular atelectasis myth or reality
    Laryngoscope, 2019
    Co-Authors: Michael Eliezer, Arnaud Attyé, Jeanpierre Guichard, Helene Vitaux, Antoine Guillonnet, Michel Toupet, Philippe Herman, Romain Kania, Emmanuel Houdart, Charlotte Hautefort
    Abstract:

    OBJECTIVES/HYPOTHESIS Because delayed post-contrast three-dimensional fluid-attenuated inversion recovery imaging sequences enable the distinction between the utricle and the Saccule, we raised the hypothesis that patients with vestibular atelectasis (VA) could show unilateral collapse of the utricle and the ampullas on imaging. STUDY DESIGN Retrospective case series. METHODS We retrospectively reviewed 200 patients who underwent 3 T magnetic resonance imaging (MRI) after intravenous administration of gadolinium. MRI scans were assessed for the presence of VA. The endolymphatic space was considered as collapsed when the utricle and at least two ampullas were not visible or were barely visible. RESULTS We reported four patients with VA on MRI responsible for atypical clinical presentations of acute vestibular deficit. All patients presented a specific involvement of the pars superior sensory captors (utricle, ampullas), preserving the pars inferior sensory captors (cochlea and Saccule). This was confirmed both clinically and on MRI. CONCLUSIONS Our study is the first to describe in vivo unilateral collapse of the pars superior on delayed postcontrast MRI in patients with a clinical unilateral vestibular loss. LEVEL OF EVIDENCE 4 Laryngoscope, 129:1689-1695, 2019.

  • MRI of endolymphatic hydrops in patients with Meniere’s disease: a case-controlled study with a simplified classification based on saccular morphology
    European Radiology, 2017
    Co-Authors: Arnaud Attyé, Michael Eliezer, Naïla Boudiaf, Irène Tropres, David Chechin, Sébastien Schmerber, Georges Dumas, Alexandre Krainik
    Abstract:

    Objectives Endolymphatic hydrops (EH) can be studied in patients by MRI. With the semi-quantitative grading system, previous imaging studies showed discrepancies in the occurrence and grading of EH in patients with Meniere’s disease (MD). Here, we compared the inversion of the Saccule to utricle area ratio (SURI) with the semi-quantitative method of grading conventionally used to diagnose MD. Methods Imaging was carried out on a 3-T MRI scanner. We performed 3D-FLAIR sequences 4 h after a single intravenous dose of contrast agent. Two radiologists independently studied the morphology of the inner ear structures in the healthy subjects and MD patients. Each subject was then graded on the basis of the EH semi-quantitative analysis and on saccular morphology using axial and sagittal reference slices in the vestibule plane. Results Thirty healthy subjects and 30 MD patients had MRI scans. Using the semi-quantitative method, we found no significant difference in the number of subjects with EH between the two groups. SURI was found in 15 out of 30 MD patients and in none of the 30 healthy subjects. In three MD patients the Saccule was not visible. Conclusion SURI is currently the most specific criterion for imaging diagnosis of MD. Key points • Half of MD patients presented with inversion of the Saccule to utricle ratio. • Saccular analysis is crucial when assessing patients with Meniere’s disease. • In some patients, the Saccule is not visible, suggestive of intra-labyrinthine fistulae.