Schizotypal Personality Disorder

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Chandlee C Dickey - One of the best experts on this subject based on the ideXlab platform.

  • prosodic abnormalities in Schizotypal Personality Disorder
    Schizophrenia Research, 2012
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Lawrence P Panych
    Abstract:

    Objective Patients with schizophrenia speak with blunted vocal affect but little is known regarding the prosody of persons with Schizotypal Personality Disorder (SPD). This work examined expressive prosody in SPD, its relationship to brain structure, and outlined a framework for measuring elements of prosody in clinical populations.

  • facial emotion recognition and facial affect display in Schizotypal Personality Disorder
    Schizophrenia Research, 2011
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Lawrence P Panych, Douglas P Terry, Cara Murphy, Rayna Zacks, Martha E. Shenton
    Abstract:

    Background Patients with schizophrenia have deficits in facial affect expression and detection that hinder social interactions. The goal of this study was to examine whether or not epidemiologically-related antipsychotic-naive Schizotypal Personality Disorder (SPD) subjects would have similar deficits as patients with schizophrenia.

  • factors in sensory processing of prosody in Schizotypal Personality Disorder an fmri experiment
    Schizophrenia Research, 2010
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Lawrence P Panych, Istvan A Morocz, Daniel Minney, Usman Khan
    Abstract:

    Introduction Persons diagnosed with schizophrenia demonstrate deficits in prosody recognition. To examine prosody along the schizophrenia spectrum, antipsychotic-naive Schizotypal Personality Disorder (SPD) subjects and healthy control subjects were compared. It was hypothesized that SPD subjects would perform more poorly; with cognitive and demographic factors contributing to the poor performance. The superior temporal gyrus (STG) was selected as the region-of-interest (ROI) given its known abnormalities in SPD and its important role in the processing of prosody.

  • Dichotic listening in Schizotypal Personality Disorder: evidence for gender and laterality effects.
    Schizophrenia Research, 2009
    Co-Authors: Martina M Voglmaier, Chandlee C Dickey, Margaret A Niznikiewicz, Larry J Seidman, Martha E. Shenton, Anita Madan, Robert W. Mccarley
    Abstract:

    Verbal dichotic listening performance was examined in 42 right-handed men and women with DSM-IV-defined Schizotypal Personality Disorder (SPD) and 68 right-handed controls. As expected, both male and female control groups showed a right ear advantage on a verbal dichotic listening task. Although SPD subjects in general had lower accuracy scores than comparison subjects, only male SPD subjects showed an abnormal left ear advantage that was specifically due to deficient right ear performance. The results suggest that left hemisphere temporal lobe structures may be particularly involved in male, but not female, SPD.

  • shape abnormalities of caudate nucleus in Schizotypal Personality Disorder
    Schizophrenia Research, 2009
    Co-Authors: James J Levitt, Sylvain Bouix, Chandlee C Dickey, Martina M Voglmaier, Martin Styner, Marc Niethammer, Margaret A Niznikiewicz
    Abstract:

    Background Previously, we reported abnormal volume and global shape in the caudate nucleus in Schizotypal Personality Disorder (SPD). Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures.

Martina M Voglmaier - One of the best experts on this subject based on the ideXlab platform.

  • prosodic abnormalities in Schizotypal Personality Disorder
    Schizophrenia Research, 2012
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Lawrence P Panych
    Abstract:

    Objective Patients with schizophrenia speak with blunted vocal affect but little is known regarding the prosody of persons with Schizotypal Personality Disorder (SPD). This work examined expressive prosody in SPD, its relationship to brain structure, and outlined a framework for measuring elements of prosody in clinical populations.

  • facial emotion recognition and facial affect display in Schizotypal Personality Disorder
    Schizophrenia Research, 2011
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Lawrence P Panych, Douglas P Terry, Cara Murphy, Rayna Zacks, Martha E. Shenton
    Abstract:

    Background Patients with schizophrenia have deficits in facial affect expression and detection that hinder social interactions. The goal of this study was to examine whether or not epidemiologically-related antipsychotic-naive Schizotypal Personality Disorder (SPD) subjects would have similar deficits as patients with schizophrenia.

  • factors in sensory processing of prosody in Schizotypal Personality Disorder an fmri experiment
    Schizophrenia Research, 2010
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Lawrence P Panych, Istvan A Morocz, Daniel Minney, Usman Khan
    Abstract:

    Introduction Persons diagnosed with schizophrenia demonstrate deficits in prosody recognition. To examine prosody along the schizophrenia spectrum, antipsychotic-naive Schizotypal Personality Disorder (SPD) subjects and healthy control subjects were compared. It was hypothesized that SPD subjects would perform more poorly; with cognitive and demographic factors contributing to the poor performance. The superior temporal gyrus (STG) was selected as the region-of-interest (ROI) given its known abnormalities in SPD and its important role in the processing of prosody.

  • Dichotic listening in Schizotypal Personality Disorder: evidence for gender and laterality effects.
    Schizophrenia Research, 2009
    Co-Authors: Martina M Voglmaier, Chandlee C Dickey, Margaret A Niznikiewicz, Larry J Seidman, Martha E. Shenton, Anita Madan, Robert W. Mccarley
    Abstract:

    Verbal dichotic listening performance was examined in 42 right-handed men and women with DSM-IV-defined Schizotypal Personality Disorder (SPD) and 68 right-handed controls. As expected, both male and female control groups showed a right ear advantage on a verbal dichotic listening task. Although SPD subjects in general had lower accuracy scores than comparison subjects, only male SPD subjects showed an abnormal left ear advantage that was specifically due to deficient right ear performance. The results suggest that left hemisphere temporal lobe structures may be particularly involved in male, but not female, SPD.

  • shape abnormalities of caudate nucleus in Schizotypal Personality Disorder
    Schizophrenia Research, 2009
    Co-Authors: James J Levitt, Sylvain Bouix, Chandlee C Dickey, Martina M Voglmaier, Martin Styner, Marc Niethammer, Margaret A Niznikiewicz
    Abstract:

    Background Previously, we reported abnormal volume and global shape in the caudate nucleus in Schizotypal Personality Disorder (SPD). Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures.

Martha E. Shenton - One of the best experts on this subject based on the ideXlab platform.

  • facial emotion recognition and facial affect display in Schizotypal Personality Disorder
    Schizophrenia Research, 2011
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Lawrence P Panych, Douglas P Terry, Cara Murphy, Rayna Zacks, Martha E. Shenton
    Abstract:

    Background Patients with schizophrenia have deficits in facial affect expression and detection that hinder social interactions. The goal of this study was to examine whether or not epidemiologically-related antipsychotic-naive Schizotypal Personality Disorder (SPD) subjects would have similar deficits as patients with schizophrenia.

  • Dichotic listening in Schizotypal Personality Disorder: evidence for gender and laterality effects.
    Schizophrenia Research, 2009
    Co-Authors: Martina M Voglmaier, Chandlee C Dickey, Margaret A Niznikiewicz, Larry J Seidman, Martha E. Shenton, Anita Madan, Robert W. Mccarley
    Abstract:

    Verbal dichotic listening performance was examined in 42 right-handed men and women with DSM-IV-defined Schizotypal Personality Disorder (SPD) and 68 right-handed controls. As expected, both male and female control groups showed a right ear advantage on a verbal dichotic listening task. Although SPD subjects in general had lower accuracy scores than comparison subjects, only male SPD subjects showed an abnormal left ear advantage that was specifically due to deficient right ear performance. The results suggest that left hemisphere temporal lobe structures may be particularly involved in male, but not female, SPD.

  • mri abnormalities of the hippocampus and cavum septi pellucidi in females with Schizotypal Personality Disorder
    Schizophrenia Research, 2007
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Larry J Seidman, Erin Connor, Martha E. Shenton
    Abstract:

    Objective This study examined MRI hippocampal volume and cavum septi pellucidi (CSP) in female subjects with Schizotypal Personality Disorder (SPD) and comparison subjects.

  • clinical cognitive and social characteristics of a sample of neuroleptic naive persons with Schizotypal Personality Disorder
    Schizophrenia Research, 2005
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Larry J Seidman, Sunnie Kim, Martha E. Shenton
    Abstract:

    Introduction Schizotypal Personality Disorder (SPD) shares with schizophrenia many biological features, yet little is known about the clinical characteristics of persons diagnosed with this Disorder. This report describes the clinical, cognitive and socio-occupational characteristics of a community sample of subjects diagnosed with SPD.

  • An MRI Study of Superior Temporal Gyrus Volume in Women With Schizotypal Personality Disorder
    American Journal of Psychiatry, 2003
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Larry J Seidman, Susan Demeo, Melissa Frumin, Martha E. Shenton
    Abstract:

    Objective: An abnormal superior temporal gyrus has figured prominently in schizophrenia research, and left superior temporal gyrus volume has been shown to be smaller in male subjects with Schizotypal Personality Disorder. This is the first structural magnetic resonance imaging study to examine a group of female subjects with Schizotypal Personality Disorder. Method: The superior temporal gyrus was drawn on coronal images acquired from female subjects recruited from the community (Schizotypal Personality Disorder group: N=21, comparison group: N=29). Results: There were no gray matter volume differences in the left or right superior temporal gyrus between the subjects with Schizotypal Personality Disorder and the comparison subjects. Within the Schizotypal Personality Disorder group, however, there was an interaction between hemisphere and family history of mental illness. Moreover, subjects with Schizotypal Personality Disorder did demonstrate formal thought Disorder and a negative correlation between left superior temporal gyrus volume and odd speech. Conclusions: This study of female subjects with Schizotypal Personality Disorder showed no superior temporal gyrus volume differences, but preliminary findings indicate that among female subjects with Schizotypal Personality Disorder, there is a left–right difference in those who have a family history of mental illness relative to those who do not. These data also suggest an association between abnormal speech and left superior temporal gyrus volume, a finding similar to that found in schizophrenia. Results from this study thus clearly reinforce the importance of studying female subjects separately.

Margaret A Niznikiewicz - One of the best experts on this subject based on the ideXlab platform.

  • prosodic abnormalities in Schizotypal Personality Disorder
    Schizophrenia Research, 2012
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Lawrence P Panych
    Abstract:

    Objective Patients with schizophrenia speak with blunted vocal affect but little is known regarding the prosody of persons with Schizotypal Personality Disorder (SPD). This work examined expressive prosody in SPD, its relationship to brain structure, and outlined a framework for measuring elements of prosody in clinical populations.

  • facial emotion recognition and facial affect display in Schizotypal Personality Disorder
    Schizophrenia Research, 2011
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Lawrence P Panych, Douglas P Terry, Cara Murphy, Rayna Zacks, Martha E. Shenton
    Abstract:

    Background Patients with schizophrenia have deficits in facial affect expression and detection that hinder social interactions. The goal of this study was to examine whether or not epidemiologically-related antipsychotic-naive Schizotypal Personality Disorder (SPD) subjects would have similar deficits as patients with schizophrenia.

  • factors in sensory processing of prosody in Schizotypal Personality Disorder an fmri experiment
    Schizophrenia Research, 2010
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Lawrence P Panych, Istvan A Morocz, Daniel Minney, Usman Khan
    Abstract:

    Introduction Persons diagnosed with schizophrenia demonstrate deficits in prosody recognition. To examine prosody along the schizophrenia spectrum, antipsychotic-naive Schizotypal Personality Disorder (SPD) subjects and healthy control subjects were compared. It was hypothesized that SPD subjects would perform more poorly; with cognitive and demographic factors contributing to the poor performance. The superior temporal gyrus (STG) was selected as the region-of-interest (ROI) given its known abnormalities in SPD and its important role in the processing of prosody.

  • Dichotic listening in Schizotypal Personality Disorder: evidence for gender and laterality effects.
    Schizophrenia Research, 2009
    Co-Authors: Martina M Voglmaier, Chandlee C Dickey, Margaret A Niznikiewicz, Larry J Seidman, Martha E. Shenton, Anita Madan, Robert W. Mccarley
    Abstract:

    Verbal dichotic listening performance was examined in 42 right-handed men and women with DSM-IV-defined Schizotypal Personality Disorder (SPD) and 68 right-handed controls. As expected, both male and female control groups showed a right ear advantage on a verbal dichotic listening task. Although SPD subjects in general had lower accuracy scores than comparison subjects, only male SPD subjects showed an abnormal left ear advantage that was specifically due to deficient right ear performance. The results suggest that left hemisphere temporal lobe structures may be particularly involved in male, but not female, SPD.

  • shape abnormalities of caudate nucleus in Schizotypal Personality Disorder
    Schizophrenia Research, 2009
    Co-Authors: James J Levitt, Sylvain Bouix, Chandlee C Dickey, Martina M Voglmaier, Martin Styner, Marc Niethammer, Margaret A Niznikiewicz
    Abstract:

    Background Previously, we reported abnormal volume and global shape in the caudate nucleus in Schizotypal Personality Disorder (SPD). Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures.

Robert W. Mccarley - One of the best experts on this subject based on the ideXlab platform.

  • prosodic abnormalities in Schizotypal Personality Disorder
    Schizophrenia Research, 2012
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Lawrence P Panych
    Abstract:

    Objective Patients with schizophrenia speak with blunted vocal affect but little is known regarding the prosody of persons with Schizotypal Personality Disorder (SPD). This work examined expressive prosody in SPD, its relationship to brain structure, and outlined a framework for measuring elements of prosody in clinical populations.

  • Dichotic listening in Schizotypal Personality Disorder: evidence for gender and laterality effects.
    Schizophrenia Research, 2009
    Co-Authors: Martina M Voglmaier, Chandlee C Dickey, Margaret A Niznikiewicz, Larry J Seidman, Martha E. Shenton, Anita Madan, Robert W. Mccarley
    Abstract:

    Verbal dichotic listening performance was examined in 42 right-handed men and women with DSM-IV-defined Schizotypal Personality Disorder (SPD) and 68 right-handed controls. As expected, both male and female control groups showed a right ear advantage on a verbal dichotic listening task. Although SPD subjects in general had lower accuracy scores than comparison subjects, only male SPD subjects showed an abnormal left ear advantage that was specifically due to deficient right ear performance. The results suggest that left hemisphere temporal lobe structures may be particularly involved in male, but not female, SPD.

  • mri abnormalities of the hippocampus and cavum septi pellucidi in females with Schizotypal Personality Disorder
    Schizophrenia Research, 2007
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Larry J Seidman, Erin Connor, Martha E. Shenton
    Abstract:

    Objective This study examined MRI hippocampal volume and cavum septi pellucidi (CSP) in female subjects with Schizotypal Personality Disorder (SPD) and comparison subjects.

  • clinical cognitive and social characteristics of a sample of neuroleptic naive persons with Schizotypal Personality Disorder
    Schizophrenia Research, 2005
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Larry J Seidman, Sunnie Kim, Martha E. Shenton
    Abstract:

    Introduction Schizotypal Personality Disorder (SPD) shares with schizophrenia many biological features, yet little is known about the clinical characteristics of persons diagnosed with this Disorder. This report describes the clinical, cognitive and socio-occupational characteristics of a community sample of subjects diagnosed with SPD.

  • An MRI Study of Superior Temporal Gyrus Volume in Women With Schizotypal Personality Disorder
    American Journal of Psychiatry, 2003
    Co-Authors: Chandlee C Dickey, Margaret A Niznikiewicz, Martina M Voglmaier, Robert W. Mccarley, Larry J Seidman, Susan Demeo, Melissa Frumin, Martha E. Shenton
    Abstract:

    Objective: An abnormal superior temporal gyrus has figured prominently in schizophrenia research, and left superior temporal gyrus volume has been shown to be smaller in male subjects with Schizotypal Personality Disorder. This is the first structural magnetic resonance imaging study to examine a group of female subjects with Schizotypal Personality Disorder. Method: The superior temporal gyrus was drawn on coronal images acquired from female subjects recruited from the community (Schizotypal Personality Disorder group: N=21, comparison group: N=29). Results: There were no gray matter volume differences in the left or right superior temporal gyrus between the subjects with Schizotypal Personality Disorder and the comparison subjects. Within the Schizotypal Personality Disorder group, however, there was an interaction between hemisphere and family history of mental illness. Moreover, subjects with Schizotypal Personality Disorder did demonstrate formal thought Disorder and a negative correlation between left superior temporal gyrus volume and odd speech. Conclusions: This study of female subjects with Schizotypal Personality Disorder showed no superior temporal gyrus volume differences, but preliminary findings indicate that among female subjects with Schizotypal Personality Disorder, there is a left–right difference in those who have a family history of mental illness relative to those who do not. These data also suggest an association between abnormal speech and left superior temporal gyrus volume, a finding similar to that found in schizophrenia. Results from this study thus clearly reinforce the importance of studying female subjects separately.