The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Marc Goldstein - One of the best experts on this subject based on the ideXlab platform.
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home testing may not improve postvasectomy Semen Analysis compliance
Urology Practice, 2021Co-Authors: Nahid Punjani, Miriam Andrusier, Russell Hayden, Vanessa Dudley, Eliana Matosvargas, Marc GoldsteinAbstract:AbstractIntroduction:Vasectomy is the most effective form of permanent male contraception. Although vasectomy techniques and outcomes have steadily improved, postvasectomy Semen Analysis compliance...
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correlation of ultrasound measured venous size and reversal of flow with valsalva with improvement in Semen Analysis parameters after varicocelectomy
Fertility and Sterility, 2006Co-Authors: Jonathan D Schiff, Philip S Li, Marc GoldsteinAbstract:We studied 68 men with varicoceles to determine preoperative parameters that are associated with improvements in Semen Analysis after varicocelectomy. Ultrasound-measured venous diameter and reversal of flow were found to correlate with successful outcome.
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increased incidence of testicular cancer in men presenting with infertility and abnormal Semen Analysis
The Journal of Urology, 2005Co-Authors: Jay D Raman, Craig Nobert, Marc GoldsteinAbstract:ABSTRACTPurpose:: We determined the standardized incidence ratio of testicular cancer in infertile men presenting with an abnormal Semen Analysis compared to the general population.Materials and Methods:: The charts from more than 3,800 men presenting with infertility and abnormal Semen Analysis during a 10-year period were retrospectively reviewed. The incidence of testicular tumors diagnosed in this group was compared to that of race and age matched controls during the same period from the general population (as reported by the Surveillance, Epidemiology and End Results [SEER] database).Results:: Of 3,847 men 10 (0.3%) with infertility and abnormal Semen Analysis were diagnosed with testicular tumors. Mean patient age was 32.6 years (range 25 to 52) and all 10 men were diagnosed with a seminomatous germ cell tumor. Two men had a history of cryptorchidism while the remaining 8 had no identifiable risk factors for testicular cancer. The SEER database reported an incidence of 10.6 cases of testicular cance...
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Relationship between Semen cultures, leukospermia, and Semen Analysis in men undergoing fertility evaluation
Fertility and Sterility, 2003Co-Authors: David M Rodin, Davise H. Larone, Marc GoldsteinAbstract:Abstract Objective To determine the correlation between Semen cultures, Semen Gram stains, leukospermia, and Semen Analysis parameters in asymptomatic men undergoing fertility evaluation. Design Prospective clinical study. Setting Infertility clinic at a university teaching hospital. Patient(s) Two hundred ninety-nine asymptomatic men undergoing fertility evaluation. Intervention(s) After an antibacterial skin preparation, all men gave Semen specimens for culture, Gram stains, Semen Analysis, and assessment for leukospermia. Main outcome measure(s) A comparison of the presence or absence of bacteriospermia, the specific bacterial isolate, the quantity of bacteriospermia, the presence or absence of leukospermia, and Semen Analysis parameters. Result(s) The presence or absence of bacteriospermia or leukospermia did not correlate with each other. Leukospermia did not correlate with Semen parameters. Staphylococcus species was the most common isolate (25.4% of all patients) and did not correlate with Semen parameters or leukospermia. Streptococcus viridans (15.4% of all patients) and Enterococcus faecalis (7.4% of all patients) were the next most common isolates and were associated with statistically significantly poorer Semen quality. Conclusion(s) Leukospermia is a poor marker for either bacteriospermia or impaired Semen quality. Staphylococcus species are commonly isolated but appear to be innocuous. Streptococcus viridans and Enterococcus faecalis are associated with poorer Semen quality and may warrant treatment.
Giuseppe Di Caprio - One of the best experts on this subject based on the ideXlab platform.
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holographic imaging of unlabelled sperm cells for Semen Analysis a review
Journal of Biophotonics, 2015Co-Authors: Giuseppe Di Caprio, M A Ferrara, Lisa Miccio, Francesco Merola, Pasquale Memmolo, Pietro Ferraro, Giuseppe CoppolaAbstract:Quantitative phase maps of living swimming spermatozoa. Male reproductive health in both humans and animals is an important research field in biological study. In order to characterize the morphology, the motility and the concentration of the sperm cells, which are the most important parameters to feature them, digital holography demonstrated to be an attractive technique. Indeed, it is a label-free, non-invasive and high-resolution method that enables the characterization of live specimen. The review is intended both for summarizing the state-of-art on the Semen Analysis and recent achievement obtained by means of digital holography and for exploring new possible applications of digital holography in this field.
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holographic imaging of unlabelled sperm cells for Semen Analysis a review
arXiv: Biological Physics, 2014Co-Authors: Giuseppe Di Caprio, M A Ferrara, Lisa Miccio, Francesco Merola, Pasquale Memmolo, Pietro Ferraro, Giuseppe CoppolaAbstract:Male reproductive health in both humans and animals is an important research field in biological study. In order to characterize the morphology, the motility and the concentration of the sperm cells, which are the most important parameters to feature them, digital holography demonstrated to be an attractive technique. Indeed, it is a labelfree, non-invasive and high-resolution method that enables the characterization of live specimen. The review is intended both for summarize the state-of-art on the Semen Analysis and recent achievement obtained by means of digital holography and for exploring new possible applications of digital holography in this field.
Sergio Oehninger - One of the best experts on this subject based on the ideXlab platform.
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Semen Analysis and sperm function testing
Asian Journal of Andrology, 2012Co-Authors: Daniel R Franken, Sergio OehningerAbstract:Despite controversy regarding the clinical value of Semen Analysis, male fertility investigation still relies on a standardized Analysis of the Semen parameters. This is especially true for infertility clinics in both developing and developed countries. Other optional tests or sophisticated technologies have not been widely applied. The current review addresses important changes in the Analysis of Semen as described in the new World Health Organization (WHO) manual for Semen Analysis. The most important change in the manual is the use of evidence-based publications as references to determine cutoff values for normality. Apart from the above mentioned changes, the initial evaluation and handling methods remain, in most instances, the same as in previous editions. Furthermore, the review evaluates the importance of quality control in andrology with emphasis on the evaluation of sperm morphology. WHO sperm morphology training programmes for Sub-Saharan countries were initiated at Tygerberg Hospital in 1995. The external quality control programme has ensured that the majority of participants have maintained their morphological reading skills acquired during initial training. This review reports on current sperm functional tests, such as the induced acrosome reaction, and sperm-zona pellucida binding assays, as well as the impact of sperm quality in terms of DNA integrity, and the relationship of sperm function tests to sperm morphology.
Wolfgang Schulze - One of the best experts on this subject based on the ideXlab platform.
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successful testicular sperm extraction tese in spite of high serum follicle stimulating hormone and azoospermia correlation between testicular morphology tese results Semen Analysis and serum hormone values in 103 infertile men
Human Reproduction, 1998Co-Authors: D Jezek, U A Knuth, Wolfgang SchulzeAbstract:Spermatozoa recovered from testicular biopsies can be used through intracytoplasmic sperm injection (ICSI) to achieve a pregnancy. To assess the likelihood of successful testicular sperm extraction (TESE) in men suffering from severe oligo- or azoospermia, bilateral biopsy specimens were obtained. Following semi-thin sectioning, the morphology of testicular samples was graded according to a modified Johnsen score. TESE was performed in parallel to this histological examination. The number of isolated spermatozoa was assessed in a semiquantitative way. From 103 patients investigated, 64 (62.1%) showed azoospermia in a preceding Semen Analysis and 29 (28.2%) patients had sperm concentrations between 0.1 and 1 x 10(6)/ml. In 10 patients who had higher sperm counts, most spermatozoa were non-motile. Spermatozoa could be detected after TESE in the testicular tissue of 49 (77%) azoospermic men. When follicle stimulating hormone (FSH) concentration was normal, most patients had detectable spermatozoa after TESE. Nearly one-third of patients with mildly elevated FSH had no spermatozoa. Thirty-nine percent of patients in whom FSH was elevated to more than twice normal and 50% of patients with grossly elevated FSH had no detectable spermatozoa. In all, 82.8% of men with sperm concentrations between 0.1 and 1x10(6)/ml in their ejaculate showed spermatozoa in the tissue sample after TESE. Our data demonstrate that, contrary to previous recommendations, infertile men with azoospermia and high FSH values should be reconsidered for testicular biopsy, provided that tissue samples can be cryopreserved for later TESE/ICSI treatment.
Harris M Nagler - One of the best experts on this subject based on the ideXlab platform.
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male factor infertility a solitary Semen Analysis can never predict normal fertility
Nature Reviews Urology, 2011Co-Authors: Harris M NaglerAbstract:The fact that Semen Analysis cannot predict fertility has long been a source of frustration for both patients and physicians. Studies have demonstrated that Semen analyses have poor predictive value for fertility status. Thus, the WHO reference values for human Semen characteristics are of particular interest to anyone attempting to conceive and to the professionals who must counsel these individuals.
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the natural history of partial ejaculatory duct obstruction
The Journal of Urology, 2002Co-Authors: Harris M Nagler, Michael Rotman, Edward Zoltan, Harry FischAbstract:Ejaculatory duct obstruction is a rare but treatable cause of male infertility. We report an unusual case of progression from partial to complete ejaculatory duct obstruction after therapeutic left varicocelectomy. CASE REPORT A 34-year-old man with no significant medical or surgical history presented for evaluation of primary infertility. The patient had normal sexual development and no history of trauma or genitourinary infection. Physical examination was only significant for slight testicular asymmetry and a grade 2 of 3 left varicocele. Semen Analysis revealed a volume of 1.1 cc (normal greater than 2.0), 65.8 million sperm (normal greater than 40 million/cc), 35% motility (normal greater than 50%) and 10% normal forms (normal greater than 14%, Kruger strict criteria). A repeat Semen Analysis was similar. Post-ejaculatory urine did not demonstrate any sperm. Endocrine profile was normal. Transrectal ultrasound demonstrated a right seminal vesicle measuring 1.4 cm. anteroposteriorly, which is the upper limit of normal (fig. 1) and a left seminal vesicle that measured 1.1 cm. anteroposteriorly. Figure 2 shows the area of possible obstruction of the ejaculatory ducts. Treatment options included transurethral resection of the ejaculatory ducts, microsurgical varicocelectomy or assisted reproductive techniques. The patient chose to undergo left microsurgical varicocelectomy. The varicocele resolved postoperatively. Postoperative Semen Analysis demonstrated azoospermia (volume 0.9 cc, fructose barely positive), which was confirmed on repeat Analysis. Repeat transrectal ultrasound was similar to the initial study. Transurethral resection of the ejaculatory ducts was performed and pathological
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response of routine Semen Analysis and critical assessment of sperm morphology by kruger classification to therapeutic varicocelectomy
The Journal of Urology, 1997Co-Authors: Monica H Vazquezlevin, Patricia Friedmann, Svetlana I Goldberg, Nadine E Medley, Harris M NaglerAbstract:AbstractPurpose: We studied the effect of varicocelectomy on Kruger morphology and Semen parameters.Materials and Methods: A total of 33 subfertile men diagnosed with varicoceles was evaluated 3 months before, and 3 to 4 and 6 to 8 months after varicocelectomy. Evaluation involved routine Semen Analysis and sperm morphology using Kruger classification.Results: Significant improvement in sperm concentration and count was found after varicocelectomy (sperm count preoperatively 117.1 +/− 29, 3 to 4 months postoperatively 162.5 +/− 41 and 6 to 8 months postoperatively 139.8 +/− 25 million sperm, p = 0.0095). Using Kruger classification, evaluation of sperm morphology revealed overall significant increase in percentage of normal A forms at 3 to 4 and 6 to 8 months after surgery (from 9.8 +/− 5.8 % A forms, 13.6 +/− 7.7 % A forms, and 14.5 +/− 7.5 % A forms, respectively, p = 0.0002, normal greater than 14%). Twelve of the 26 patients (46%) with abnormal sperm morphology preoperatively and greater than 4% A for...
