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Wenbo Peng - One of the best experts on this subject based on the ideXlab platform.

  • syndrome differentiation and treatment of taiyang disease in Shanghan Lun
    Journal of Chinese Integrative Medicine, 2009
    Co-Authors: Xue Yang, Wenbo Peng
    Abstract:

    OBJECTIVE: To explore the laws in syndrome differentiation of Taiyang disease and the prescriptions and herbs used in its treatment in Shanghan Lun (Treatise on Febrile Diseases). METHODS: The occurrence rates of main syndromes of Taiyang disease, and the usage frequency of the prescriptions and herbs in its treatment were calculated, and the laws in syndrome differentiation and herbal medication were analyzed by hierarchical clustering analysis. RESULTS: Fever and aversion to cold were found to be the main symptoms of Taiyang disease and usually accompanied with headache, absent sweating, neck stiff, floating and tight pulse, and body ache. The accompanying or aggravated symptoms could be classified into Lung system syndrome with the manifestations of sweating and asthma, spleen-deficiency syndrome with the manifestations of gastric fullness and diarrhea, stomach syndrome with vomit and constipation. Guizhi decoction was the main prescription used in the treatment of Taiyang disease. Mahuang (Herba Ephedrae) matching Xingren (Semen Armeniacae), Dahuang (Radix et Rhizoma Rhei) matching Mangxiao (Natrii Sulfas), Baizhu (Rhizoma Atractylodes Macrocephalae) matching Fuling (Poria), Fuzi (Radix Aconiti Lateralis) matching Ganjiang (Rhizoma Zingiberis), Chaihu (Radix Bupleuri) matching Huangqin (Radix Scutellariae), Banxia (Rhizoma Pinelliae), and Renshen (Radix Ginseng) as the main compatibilities were used in treating Lung diseases, stomach diseases, spleen-deficiency diseases, kidney-deficiency diseases and Shaoyang diseases respectively. CONCLUSION: Exterior syndrome, as a common syndrome in Taiyang disease, is usually treated with Guizhi decoction. The change in syndromes from upper-energizer to lower-energizer in exterior disease can be found from the change of symptoms and the use of herbs. And the development from defending stage to qi stage in exterior disease can be found in the use of prescriptions in Shanghan Lun.

Xue Yang - One of the best experts on this subject based on the ideXlab platform.

  • dose response patterns of radix glycyrrhizae in Shanghan Lun
    Journal of Chinese Integrative Medicine, 2009
    Co-Authors: Xue Yang, Xiangliang Kong
    Abstract:

    : In order to explore the dose-response patterns of Gancao (Radix Glycyrrhizae) in Shanghan Lun (Treatise on Febrile Diseases), all prescriptions containing Gancao in Shanghan Lun were analyzed by frequency and hierarchical clustering analysis. The doses of Gancao used in Shanghan Lun ranged from six zhu (Chinese unit, and one zhu is equal to 0.65 g) to four liang (Chinese unit, and one liang is equal to 15.625 g). Doses of one, two, three or four liang were commonly used. One liang Gancao as juvantia was usually matched with Mahuang (Herba Ephedrae), Xingren (Semen Armeniacae) and Guizhi (Ramulus Cinnamomi) for restricting the excessive diaphoresis of Mahuang. Two liang Gancao was often matched with some couple drugs, such as Guizhi and Shaoyao (Radix Paeoniae), Shigao (Gypsum Fibrosum) and Zhimu (Rhizoma Anemarrhenae), Fuzi (Radix Aconiti Lateralis) and Ganjiang (Rhizoma Zingiberis), for warming yang to supplement qi, nourishing yin, detoxifying Fuzi, and preventing qi impairment from heat evil. Three liang Gancao was mainly matched with Banxia (Rhizoma Pinelliae) or Renshen (Radix Ginseng) for treating middle energizer emesis. Four liang Gancao was matched with Ganjiang or tonifying herbs for invigorating vital qi and relieving spasm in deficiency syndromes with contraction, palpitation or diarrhea. Gancao is used for treating many syndromes in Shanghan Lun. It is frequently used to treat excess or heat syndromes with one or two liang in a dose and deficiency or cold syndromes with three or four liang in a dose.

  • syndrome differentiation and treatment of taiyang disease in Shanghan Lun
    Journal of Chinese Integrative Medicine, 2009
    Co-Authors: Xue Yang, Wenbo Peng
    Abstract:

    OBJECTIVE: To explore the laws in syndrome differentiation of Taiyang disease and the prescriptions and herbs used in its treatment in Shanghan Lun (Treatise on Febrile Diseases). METHODS: The occurrence rates of main syndromes of Taiyang disease, and the usage frequency of the prescriptions and herbs in its treatment were calculated, and the laws in syndrome differentiation and herbal medication were analyzed by hierarchical clustering analysis. RESULTS: Fever and aversion to cold were found to be the main symptoms of Taiyang disease and usually accompanied with headache, absent sweating, neck stiff, floating and tight pulse, and body ache. The accompanying or aggravated symptoms could be classified into Lung system syndrome with the manifestations of sweating and asthma, spleen-deficiency syndrome with the manifestations of gastric fullness and diarrhea, stomach syndrome with vomit and constipation. Guizhi decoction was the main prescription used in the treatment of Taiyang disease. Mahuang (Herba Ephedrae) matching Xingren (Semen Armeniacae), Dahuang (Radix et Rhizoma Rhei) matching Mangxiao (Natrii Sulfas), Baizhu (Rhizoma Atractylodes Macrocephalae) matching Fuling (Poria), Fuzi (Radix Aconiti Lateralis) matching Ganjiang (Rhizoma Zingiberis), Chaihu (Radix Bupleuri) matching Huangqin (Radix Scutellariae), Banxia (Rhizoma Pinelliae), and Renshen (Radix Ginseng) as the main compatibilities were used in treating Lung diseases, stomach diseases, spleen-deficiency diseases, kidney-deficiency diseases and Shaoyang diseases respectively. CONCLUSION: Exterior syndrome, as a common syndrome in Taiyang disease, is usually treated with Guizhi decoction. The change in syndromes from upper-energizer to lower-energizer in exterior disease can be found from the change of symptoms and the use of herbs. And the development from defending stage to qi stage in exterior disease can be found in the use of prescriptions in Shanghan Lun.

Liang Hualon - One of the best experts on this subject based on the ideXlab platform.

  • Discussion of Shanghan Lun: The Cholera for Cholera,Cholera Difference with Typhoid——the Syndrome Differentiation and Treatment of Cholera
    China Journal of Chinese Medicine, 2020
    Co-Authors: Liang Hualon
    Abstract:

    ① " treatise on febrile diseases",which under the corresponding syndrome of six-channel diseases has set up a similar card,is used to identify,it is in the theory of differential. And setting up a cholera after six-channel diseases,identification with the " typhoid fever",it can be regarded as general identification,both the " disease" to identify,and the " syndrome differentiation",there is little " symptoms",making the differential diagnosis of typhoid fever,from the disease to the card,and then to sui generis,it has opened up the differential diagnosis of disease. ②Four inverse of shaoyin disease and syndrome of jue inverse jue Yin disease is caused by a Yang phase and not more,real manhood limbs jue inverse,no matter in theory or in practice it is difficult to support,Yang deficiency disease is cold,especially in the arms and legs fearing to the cold,but not necessarily brothers temperature decrease,Yang deficiency leads to inverse cold limbs rarely,cold dish,hot,qi depression and evil resistance and gas phase and is the limbs jue the main reason for the inverse.

  • discussion of Shanghan Lun the cholera for cholera cholera difference with typhoid the syndrome differentiation and treatment of cholera
    China Journal of Chinese Medicine, 2015
    Co-Authors: Liang Hualon
    Abstract:

    ① " treatise on febrile diseases",which under the corresponding syndrome of six-channel diseases has set up a similar card,is used to identify,it is in the theory of differential. And setting up a cholera after six-channel diseases,identification with the " typhoid fever",it can be regarded as general identification,both the " disease" to identify,and the " syndrome differentiation",there is little " symptoms",making the differential diagnosis of typhoid fever,from the disease to the card,and then to sui generis,it has opened up the differential diagnosis of disease. ②Four inverse of shaoyin disease and syndrome of jue inverse jue Yin disease is caused by a Yang phase and not more,real manhood limbs jue inverse,no matter in theory or in practice it is difficult to support,Yang deficiency disease is cold,especially in the arms and legs fearing to the cold,but not necessarily brothers temperature decrease,Yang deficiency leads to inverse cold limbs rarely,cold dish,hot,qi depression and evil resistance and gas phase and is the limbs jue the main reason for the inverse.

  • discussion of Shanghan Lun the forty first chapter shaoyin cold of actual situation the square to add and subtract profound truth differentiation of syndrome of yin cold less on treatment
    China Journal of Chinese Medicine, 2015
    Co-Authors: Liang Hualon
    Abstract:

    ①Cold syndrome is mainly by cold excess,cold excess due to cold injury Yang,cold excess and Yang deficiency is the principal contradiction,and cold excess is the main aspect of principal contradiction is very cold,forced Yang Sheng outside more upward and form a lattice Yang Dai Yang syndrome. Deficiency cold syndrome is due to Yang deficiency constitution,Yang deficiency and cold,is the principal contradiction,and Yang deficiency is the main aspect of the contradiction,andderived many such as cold due to Yang and diffuse,drinking water retention,sepsis and otherrelevant pathological spondylolisthesis. ②The Dai Yang syndrome is Yin cold excess,forced Yang up,less outside Yang,only the upper part of the head,only to meet such as red makeup; GE Yang syndrome is Yin cold excess polar,forced Yang outside more,Yang large external floating head,body surface are so see fever,aversion to cold,his complexion is red. Dai Yang is Yin cold Yang and repelling,so wear Yang is also a lattice Yang; Yang syndrome on lattice Yang also floating head surface,so the lattice Yang card also contains Dai Yang. ③ShanghanLun prescription has its rules,ways and modes. The rules for addition and subtraction with the disease,that is,no matter how the syndrome pathogenesis,symptoms for only the prescription; dialectical addition and subtraction is according to the main pathogenesis,combined with clinical symptoms,drug addition and subtraction and pathogenesis of the corresponding. In the form of fixed mode,addition and subtraction is imminent in the main square formed after the fixed prescription; flexible way is based on the main square on the basis of clinical symptoms of different drug addition and subtraction.Mode is divided into parallel mode,namely,in the original basis of addition and subtraction drug or dosage; progressive mode in the original party together with drugs,followed byremoving the drug previously introduced plus other drugs.

  • discussion of Shanghan Lun syndrome of sini powder with qi depression and urgent diarrhea of shaoyin belongs to warm disease syndrome differentiation and treatment of shaoyin disease with heat transformation syndrome
    China Journal of Chinese Medicine, 2015
    Co-Authors: Liang Hualon
    Abstract:

    1Sini of Sini Powder is because of unfavourable Shaoyin Qi activity,less pivotal,cannot play its pivotal function of Yin and Yang,which lead to dispersion of Yin and Yang are abnormal,Yang Qi cannot reach to the limbs. Because the disfluency of the Qi activity,so the water channels is abnormal,cough due to Lung Qi,palpitate due to dispersion of heart Qi,difficult urination of disfluency of the water channels,stomachache due to stagnation of the circulation of vital energy,so it is urgent diarrhea. 2Article 321 Shaoyin disease,urination is clear,under the heart is pain,mouth is dry,can purgating,suitable for Dachengqi decoction. This syndrome is not heat fecaloma with watery discharge,not Yangming fuviscera excess is interacts exterior and interior with Shaoyin heart and Hand-Taiyangsmall intestine,heart-fire hyperactivity,move down to small intestine,small intestine can not separating the useful from the waste,lead to the gall move down with follow,so the urination is clear. Because dereliction of duty of separating the useful from the waste,water can not metaplasia body fluid,more urination and dry mouth. Heat injured stagnation of the circulation of vital energy,Qi activity block lead to pain. The general pathogenesis is heat evil excess,hot move to small intestine,duty of separating the useful from the waste,Qi activity is block. 3Shaoyin with diarrhea,which is an excess heat syndrome with evil thermalization at Shaoyin,fire behavior is prosperous,the result of injuring fluid and lose Qi is more and more serious,so should be removed evil heat by Dachengqi decoction. The pathogenesis is more heat,thermoae and that injured fluid. Quikly purgating,which means purgating heat as soon and possibly. It' s relate to the nature,not relate to the dry excrement,so not can be used Dachengqi decoction,forced related to Yangming. Quikly purgating is the theoretical foundation of later generations' expert of warm disease:liking purgation early of warm disease. Shaoyin purgating syndrome is distinct with stroke and cold damage.

S N Shen - One of the best experts on this subject based on the ideXlab platform.

  • A textual research on the spreading of Jin Gui Yu Han Jing
    Chinese journal of medical history, 2020
    Co-Authors: Y Fu, S N Shen
    Abstract:

    Jin Gui Yu Han Jing(金匮玉函经, The Jade Case Classic of the Golden Cabinet) and Shanghan Lun(伤寒论, Treatise on Febrile Diseases) have similar contents but different names, and they were handed down after being collated by the Medical Records Bureau in 1066, the third year of the Northern Song Dynasty. At present, Jin Gui Yu Han Jing is Chen Shijie's edition in the Qing Dynasty. Chen Shijie got the manuscript of Song Dynasty from He Zhuo, a scholar of Qing Dynasty, then corrected it, and published it in 1717. By searching the citations from Jin Gui Yu Han Jing in medical works from 1066 to 1717, and dividing them into two categories: direct quotation and indirect quotation, so as to investigate the spreading situation of Jin Gui Yu Han Jing since Song Dynasty. According to this, it can be inferred that Jin Gui Yu Han Jing had not been found by doctors in Yuan and Ming Dynasties. Key words: Jin Gui Yu Han Jing; Song Dynasty edition; citation; Shanghan Lun

  • A textual research on the spreading of Jin Gui Yu Han Jing
    Zhonghua yi shi za zhi (Beijing China : 1980), 2020
    Co-Authors: Y Fu, S N Shen
    Abstract:

    Jin Gui Yu Han Jing(, The Jade Case Classic of the Golden Cabinet) and Shanghan Lun(, Treatise on Febrile Diseases) have similar contents but different names, and they were handed down after being collated by the Medical Records Bureau in 1066, the third year of the Northern Song Dynasty. At present, Jin Gui Yu Han Jing is Chen Shijie's edition in the Qing Dynasty. Chen Shijie got the manuscript of Song Dynasty from He Zhuo, a scholar of Qing Dynasty, then corrected it, and published it in 1717. By searching the citations from Jin Gui Yu Han Jing in medical works from 1066 to 1717, and dividing them into two categories: direct quotation and indirect quotation, so as to investigate the spreading situation of Jin Gui Yu Han Jing since Song Dynasty. According to this, it can be inferred that Jin Gui Yu Han Jing had not been found by doctors in Yuan and Ming Dynasties.

Shin Hwar Wu - One of the best experts on this subject based on the ideXlab platform.

  • Simultaneous use of traditional Chinese medicine (si-ni-tang) to treat septic shock patients: study protocol for a randomized controlled trial.
    Trials, 2011
    Co-Authors: Huang Chi Chen, Wen Chi Chen, Yung-hsiang Chen, Lun-chien Lo, Te Chun Hsia, Chu Hsien Wang, Shin Hwar Wu
    Abstract:

    Background Even though there are continually upgraded recommendations for managing sepsis, such as "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock", mortality is still high. Si-Ni-Tang, a remedy documented in Shanghan Lun, a medical collection from ancient China, is used for treating patients with sepsis and septic shock. Using a well-designed clinical trial, we are eager to survey the effectiveness of the concurrent use of this remedy in restoring these patients' hemodynamic status, or "Yang Qi".

  • Simultaneous use of traditional Chinese medicine (Si-Ni-Tang) to treat septic shock patients: study protocol for a randomized controlled trial
    Trials, 2011
    Co-Authors: Huang Chi Chen, Wen Chi Chen, Yung-hsiang Chen, Lun-chien Lo, Te Chun Hsia, Chu Hsien Wang, Shin Hwar Wu, Yu-jun Chang, Yu-chuen Huang, Tien-hsiung Ku
    Abstract:

    Background Even though there are continually upgraded recommendations for managing sepsis, such as "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock", mortality is still high. Si-Ni-Tang, a remedy documented in Shanghan Lun, a medical collection from ancient China, is used for treating patients with sepsis and septic shock. Using a well-designed clinical trial, we are eager to survey the effectiveness of the concurrent use of this remedy in restoring these patients' hemodynamic status, or "Yang Qi". Methods/Design Patients admitted to our medical intensive care units with the diagnosis of septic shock, defined as persistent hypotension induced by sepsis despite adequate fluid resuscitation, are eligible for participation. The inclusion criteria include: age from 20 to 85 years, conditions meeting the definition of septic shock, use of vasopressors within 24 hours of entering the study, and use of a nasogastric tube for feeding. The enrolled patients are randomly allocated either to the Si-Ni-Tang group or the placebo group. The prescription of the trial drugs (Si-Ni-Tang/placebo) is 2.25 grams 4 times a day for 7 days or till shock reversal (if shock reversal occurs in less than 7 days). Data, including duration of vasopressor infusion, gender, age, co-morbidities, APACHE II score, predicted mortality, ICU mortality, ICU length of stay, hospital mortality, hospital length of stay, source of sepsis, and culture results, are collected for the following analysis. Discussion Si-Ni-Tang is composed of processed Zingiber officinale , Glycyrrhiza uralensis , and Aconitum carmichaeli . Zingiber officinale and Glycyrrhiza uralensis are found to have the ability to reduce pro-inflammatory cytokine production, to inhibit lipopolisaccharide-induced macrophage activation and function, and to lessen the bacterial load and suppress acute and chronic inflammation. Aconitum carmichaeli is known to have vasopressor activity, and positive chronotropic and inotropic effects. As this remedy has a potential benefit in treating septic shock patients, we designed a double-blind, prospective, randomized controlled trial and would like to publish the results and conclusions later. Trial Registration ClinicalTrials.gov: NCT01223430