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Dinesh Kumar Jain - One of the best experts on this subject based on the ideXlab platform.

  • Simple Evaluation of wound healing activity of polyherbal formulation of roots of Ageratum conyzoides Linn.
    Asian Journal of Research in Chemistry, 2009
    Co-Authors: Jain Sachin, Jain Neetesh, A. Tiwari, Neelam Balekar, Dinesh Kumar Jain
    Abstract:

    The present study was aim to investigate the possible effect of Ageratum conyzoides root extract on wound healing and is also include a comparable study of effect of polyherbal formulation containing Ageratum conyzoides, Ficus religiosa, Curcuma longa and Tamarindus indica, on wound healing process with respect to intact plant formulation through topical route. The wound healing property of Ageratum conyzoides appears to be due to the presence of its active principles, which accelerates the healing process and confers breaking strength to the healed wound. Further, wound healing activity by polyherbal formulation was found to be better than ageratum treated groups in rat. It may be attributed to the synergistic action of ageratum constituent and the constituent of other plants present in the polyherbal formulation.

Etienne Cavaignac - One of the best experts on this subject based on the ideXlab platform.

  • Simple Knee Value: a Simple Evaluation correlated to existing knee PROMs
    Knee Surgery Sports Traumatology Arthroscopy, 2020
    Co-Authors: Vincent Marot, Arthur Justo, Amer Alshanquiti, Nicolas Reina, Franck Accadbled, Emilie Berard, Etienne Cavaignac
    Abstract:

    Purpose The Simple Knee Value (SKV) is an outcome score in which patients are asked to grade their knee function as a percentage of that of a normal knee. The primary aim of this study was to validate the SKV by measuring its correlation with existing knee-related PROMs. Methods This was a prospective study conducted at a teaching hospital to assess the SKV’s validity. The study enrolled 47 young patients (16–54 years old), 49 older patients (≥ 55 years) and 30 healthy controls. A paper questionnaire consisting of the Lysholm, IKDC, KOOS, WOMAC and SKV was given to subjects three times (enrolment, 1-month preoperative visit and 6 months postoperative visit). The criterion validity of the SKV was determined by correlating it to existing knee PROMs using the Spearman correlation coefficient (S). SKV test–retest reliability was assessed by the intraclass correlation coefficient (ICC) between two time points (initial consultation at enrolment and preoperative visit, reflecting the same clinical condition). Responsiveness to change was determined by comparing the SKV scores before and after surgery (enrolment consultation and 6 months postoperative). Discriminative ability was determined by comparing the SKV distribution in patients and controls. Results There was a strong and significant correlation between the SKV and the gold standard Lysholm, IKDC, KOOS and WOMAC in the younger patients and the older patients ( p  

  • Simple Knee Value: a Simple Evaluation correlated to existing knee PROMs.
    Knee surgery sports traumatology arthroscopy : official journal of the ESSKA, 2020
    Co-Authors: Vincent Marot, Arthur Justo, Amer Alshanquiti, Nicolas Reina, Franck Accadbled, Emilie Berard, Etienne Cavaignac
    Abstract:

    The Simple Knee Value (SKV) is an outcome score in which patients are asked to grade their knee function as a percentage of that of a normal knee. The primary aim of this study was to validate the SKV by measuring its correlation with existing knee-related PROMs. This was a prospective study conducted at a teaching hospital to assess the SKV's validity. The study enrolled 47 young patients (16-54 years old), 49 older patients (≥ 55 years) and 30 healthy controls. A paper questionnaire consisting of the Lysholm, IKDC, KOOS, WOMAC and SKV was given to subjects three times (enrolment, 1-month preoperative visit and 6 months postoperative visit). The criterion validity of the SKV was determined by correlating it to existing knee PROMs using the Spearman correlation coefficient (S). SKV test-retest reliability was assessed by the intraclass correlation coefficient (ICC) between two time points (initial consultation at enrolment and preoperative visit, reflecting the same clinical condition). Responsiveness to change was determined by comparing the SKV scores before and after surgery (enrolment consultation and 6 months postoperative). Discriminative ability was determined by comparing the SKV distribution in patients and controls. There was a strong and significant correlation between the SKV and the gold standard Lysholm, IKDC, KOOS and WOMAC in the younger patients and the older patients (p < 0.0001). The reliability between the SKV at the initial consultation and before surgery was excellent (ICC 0.862, 95% CI 0.765; 0.921) in the younger patients, and moderate (ICC 0.506, 95% CI 0.265; 0.688) in the older patients. The SKV was responsive to change in both patient groups (p < 0.0001 for the SKV before versus 6 months after surgery). Like the other knee-specific PROMs (p < 0.0001), the SKV was able to distinguish between patients and controls (p < 0.0001). The SKV is valid as it is significantly correlated to existing knee PROMs. It is also reliable, responsive to change and discriminating. Its simplicity gives it many advantages and it can be used by physicians in their daily practice. Level II.

Jain Sachin - One of the best experts on this subject based on the ideXlab platform.

  • Simple Evaluation of wound healing activity of polyherbal formulation of roots of Ageratum conyzoides Linn.
    Asian Journal of Research in Chemistry, 2009
    Co-Authors: Jain Sachin, Jain Neetesh, A. Tiwari, Neelam Balekar, Dinesh Kumar Jain
    Abstract:

    The present study was aim to investigate the possible effect of Ageratum conyzoides root extract on wound healing and is also include a comparable study of effect of polyherbal formulation containing Ageratum conyzoides, Ficus religiosa, Curcuma longa and Tamarindus indica, on wound healing process with respect to intact plant formulation through topical route. The wound healing property of Ageratum conyzoides appears to be due to the presence of its active principles, which accelerates the healing process and confers breaking strength to the healed wound. Further, wound healing activity by polyherbal formulation was found to be better than ageratum treated groups in rat. It may be attributed to the synergistic action of ageratum constituent and the constituent of other plants present in the polyherbal formulation.

Scott Tashman - One of the best experts on this subject based on the ideXlab platform.

  • A Simple Evaluation of Anterior Cruciate Ligament Femoral Tunnel Position The Inclination Angle and Femoral Tunnel Angle
    The American journal of sports medicine, 2011
    Co-Authors: Kenneth D. Illingworth, Daniel Hensler, Jeffrey A. Macalena, Scott Tashman
    Abstract:

    Background: Postoperative determination of tunnel position after anterior cruciate ligament (ACL) reconstruction can be challenging.Hypothesis: The femoral tunnel angle and inclination angle are reliable methods for evaluating tunnel position after ACL reconstruction while aiding in determining whether an ACL reconstruction falls outside an anatomic range as defined on 3-dimensional (3D) computed tomography (CT).Study Design: Cohort study (diagnosis); Level of evidence, 3.Methods: Fifty patients were included who received single-bundle ACL reconstructions with postoperative flexion weightbearing radiographs, magnetic resonance imaging (MRI), and CT scans. Femoral tunnel angles were determined from posterior-to-anterior postoperative radiographs, and inclination angles were determined from sagittal MRI. The ACL reconstructions were grouped by surgical technique, transtibial (TT) or tibial tunnel independent (TTI), and as either falling inside or outside an anatomic range on 3D CT.Results: Patients with tun...

Vincent Marot - One of the best experts on this subject based on the ideXlab platform.

  • Simple Knee Value: a Simple Evaluation correlated to existing knee PROMs
    Knee Surgery Sports Traumatology Arthroscopy, 2020
    Co-Authors: Vincent Marot, Arthur Justo, Amer Alshanquiti, Nicolas Reina, Franck Accadbled, Emilie Berard, Etienne Cavaignac
    Abstract:

    Purpose The Simple Knee Value (SKV) is an outcome score in which patients are asked to grade their knee function as a percentage of that of a normal knee. The primary aim of this study was to validate the SKV by measuring its correlation with existing knee-related PROMs. Methods This was a prospective study conducted at a teaching hospital to assess the SKV’s validity. The study enrolled 47 young patients (16–54 years old), 49 older patients (≥ 55 years) and 30 healthy controls. A paper questionnaire consisting of the Lysholm, IKDC, KOOS, WOMAC and SKV was given to subjects three times (enrolment, 1-month preoperative visit and 6 months postoperative visit). The criterion validity of the SKV was determined by correlating it to existing knee PROMs using the Spearman correlation coefficient (S). SKV test–retest reliability was assessed by the intraclass correlation coefficient (ICC) between two time points (initial consultation at enrolment and preoperative visit, reflecting the same clinical condition). Responsiveness to change was determined by comparing the SKV scores before and after surgery (enrolment consultation and 6 months postoperative). Discriminative ability was determined by comparing the SKV distribution in patients and controls. Results There was a strong and significant correlation between the SKV and the gold standard Lysholm, IKDC, KOOS and WOMAC in the younger patients and the older patients ( p  

  • Simple Knee Value: a Simple Evaluation correlated to existing knee PROMs.
    Knee surgery sports traumatology arthroscopy : official journal of the ESSKA, 2020
    Co-Authors: Vincent Marot, Arthur Justo, Amer Alshanquiti, Nicolas Reina, Franck Accadbled, Emilie Berard, Etienne Cavaignac
    Abstract:

    The Simple Knee Value (SKV) is an outcome score in which patients are asked to grade their knee function as a percentage of that of a normal knee. The primary aim of this study was to validate the SKV by measuring its correlation with existing knee-related PROMs. This was a prospective study conducted at a teaching hospital to assess the SKV's validity. The study enrolled 47 young patients (16-54 years old), 49 older patients (≥ 55 years) and 30 healthy controls. A paper questionnaire consisting of the Lysholm, IKDC, KOOS, WOMAC and SKV was given to subjects three times (enrolment, 1-month preoperative visit and 6 months postoperative visit). The criterion validity of the SKV was determined by correlating it to existing knee PROMs using the Spearman correlation coefficient (S). SKV test-retest reliability was assessed by the intraclass correlation coefficient (ICC) between two time points (initial consultation at enrolment and preoperative visit, reflecting the same clinical condition). Responsiveness to change was determined by comparing the SKV scores before and after surgery (enrolment consultation and 6 months postoperative). Discriminative ability was determined by comparing the SKV distribution in patients and controls. There was a strong and significant correlation between the SKV and the gold standard Lysholm, IKDC, KOOS and WOMAC in the younger patients and the older patients (p < 0.0001). The reliability between the SKV at the initial consultation and before surgery was excellent (ICC 0.862, 95% CI 0.765; 0.921) in the younger patients, and moderate (ICC 0.506, 95% CI 0.265; 0.688) in the older patients. The SKV was responsive to change in both patient groups (p < 0.0001 for the SKV before versus 6 months after surgery). Like the other knee-specific PROMs (p < 0.0001), the SKV was able to distinguish between patients and controls (p < 0.0001). The SKV is valid as it is significantly correlated to existing knee PROMs. It is also reliable, responsive to change and discriminating. Its simplicity gives it many advantages and it can be used by physicians in their daily practice. Level II.