The Experts below are selected from a list of 210 Experts worldwide ranked by ideXlab platform
Mikihiko Kogo - One of the best experts on this subject based on the ideXlab platform.
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effect of lung inflation on levator veli palatini muscle activity
Journal of Dental Research, 1995Co-Authors: Hidehiko Koizumi, Mikihiko KogoAbstract:Palatal movements play a critical role in regulating oropharyngeal airflow during breathing. We hypothesized that these movements are coordinated with breathing movements via afferent signals from the lung. However, the control of palatal movements in relation to the lung remains unclear. This study was designed to define, by electromyographic techniques, the relationship between palatal movement and lung action during respiration.We performed tracheotomies on 12 mongrel dogs anesthetized with Sodium Pentobarbital and found that lung inflation augmented the activity of the levator veli palatini muscle (LVP). Two kinds of discharges were recognized during the expiratory pause following lung inflation. One was a continuous, low-amplitude discharge induced during apnea following lung inflation. The other was a transient, high-amplitude discharge which appeared immediately after lung inflation. Both of these response activities were eliminated by bilateral vagotomy. We thus concluded that palatal movements, w...
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mechanical contraction property of the levator veli palatini muscle
The Cleft Palate-Craniofacial Journal, 1991Co-Authors: Mikihiko Kogo, Juntaro Nishio, Yasushi Hamamura, Yasunobu Yasui, Kazuo Inoue, Tadashi MiyazakiAbstract:Abstract Twenty adult dogs anesthetized with Sodium Pentobarbital were used as experimental animals in an analysis of the mechanical contraction properties of the levator veli palatini muscle. The following results were obtained: the contraction time and half relaxation time of maximal isometric twitch of the muscle were revealed to be 43 msec and 33 msec, respectively; a summation curve was obtained with stimulation at 15 Hz and maximal tetanic tension was at 70 Hz. The average of the tetanic tension ratio was found to be 5.7. The maximum rate of tension rise was observed at 150 Hz, and the value was twice the rate of the twitch contraction. The duration time of the active state plateau showed values of 3.9 to 4.5 msec. The contraction time of the levator veli palatini muscle closely resembles that of the intrinsic laryngeal and the orbicularis oris muscle.
Tamotsu Shibasaki - One of the best experts on this subject based on the ideXlab platform.
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non peptidic corticotropin releasing hormone receptor type 1 antagonist reverses restraint stress induced shortening of Sodium Pentobarbital induced sleeping time of rats evidence that an increase in arousal induced by stress is mediated through crh
Neuroscience Letters, 1998Co-Authors: Keiko Arai, Hisayuki Ohata, Tamotsu ShibasakiAbstract:Stress shortens Sodium Pentobarbital (PbNa)-induced sleeping time through corticotropin-releasing hormone (CRH) in rats. We investigated whether this effect of brain CRH is mediated by CRH receptor type 1 (CRHR1) using a non-peptidic CRHR1 antagonist in rats. A 60 min period of restraint significantly shortened PbNa-induced sleeping time. This shortening was completely reversed by peripheral administration of CRHR1 antagonist. These results suggest that the stress-induced increase in arousal is mediated by CRHR1.
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neuropeptide y reverses corticotropin releasing hormone and psychological stress caused shortening of Sodium Pentobarbital induced sleep in rats
Brain Research, 1996Co-Authors: Konagi Yamada, Tamotsu Shibasaki, Chiaki Tsumori, Toshihiro Imaki, Marl Hotta, Ichiji Wakabayashi, Hiroshi DemuraAbstract:Intracerebroventricular injection of neuropeptide Y (NPY) prolonged Sodium Pentobarbital (PbNa)-induced sleep in rats. The prolongation of PbNa-induced sleep by NPY was blocked by naloxone. Both corticotropin-releasing hormone and psychological stress caused shortening of PbNa-induced sleep, and the shortening was reversed by NPY. These results suggest that NPY has a sedative action and that an opioid system in the brain mediates at least in part the action of NPY.
Jin Mo Chung - One of the best experts on this subject based on the ideXlab platform.
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an experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
Pain, 1992Co-Authors: Sun Ho Kim, Jin Mo ChungAbstract:SummaryWe attempted to develop an experimental animal model for peripheral neuropathic pain. Under Sodium Pentobarbital anesthesia, both the L5 and L6 spinal nerves (group 1) or the L5 spinal nerve alone (group 2) of one side of the rat were tightly ligated. For comparison, a parallel study was cond
Michal Abrahamowicz - One of the best experts on this subject based on the ideXlab platform.
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effects of Sodium Pentobarbital anesthesia on blood flow in skin myocutaneous and fasciocutaneous flaps in swine
Plastic and Reconstructive Surgery, 1991Co-Authors: J G Thomson, C L Kerrigan, Michal AbrahamowiczAbstract:Drug effect on flap blood flow is most commonly determined in anesthetized animals, yet the effect of the anesthetic is often poorly understood. Halothane and nitrous oxide cause profound changes in skin blood flow and thus provide an unsuitable anesthetic technique for use in measuring drug effects on skin and myocutaneous flaps in swine. The goal of this study was to determine the effects of Sodium Pentobarbital anesthesia on cardiovascular parameters and blood flow in skin, myocutaneous, and fasciocutaneous flaps in pigs. In seven pigs, 7 forelimb skin flaps, 7 forelimb fasciocutaneous flaps, 14 arterial buttock flaps, and 14 latissimus dorsi flaps were created. Blood flow was measured at 2-cm intervals along each flap while the animal was awake and anesthetized. A cardiac depressant effect of Pentobarbital was observed, but no change in blood flow could be demonstrated in control skin or control muscle. However, Pentobarbital did significantly increase blood flow in all viable portions of arterial and random skin flaps, fasciocutaneous flaps, and the cutaneous segments of the latissimus dorsi flap. These demonstrated effects of Pentobarbital should be taken into consideration in designing and analyzing studies of flap blood flow in the acute postoperative phase.
Hidehiko Koizumi - One of the best experts on this subject based on the ideXlab platform.
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effect of lung inflation on levator veli palatini muscle activity
Journal of Dental Research, 1995Co-Authors: Hidehiko Koizumi, Mikihiko KogoAbstract:Palatal movements play a critical role in regulating oropharyngeal airflow during breathing. We hypothesized that these movements are coordinated with breathing movements via afferent signals from the lung. However, the control of palatal movements in relation to the lung remains unclear. This study was designed to define, by electromyographic techniques, the relationship between palatal movement and lung action during respiration.We performed tracheotomies on 12 mongrel dogs anesthetized with Sodium Pentobarbital and found that lung inflation augmented the activity of the levator veli palatini muscle (LVP). Two kinds of discharges were recognized during the expiratory pause following lung inflation. One was a continuous, low-amplitude discharge induced during apnea following lung inflation. The other was a transient, high-amplitude discharge which appeared immediately after lung inflation. Both of these response activities were eliminated by bilateral vagotomy. We thus concluded that palatal movements, w...
