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Yuping Tang - One of the best experts on this subject based on the ideXlab platform.

  • Flavonols and flavonol glycosides from the pericarp of Sophora Japonica L.
    Journal of Plant Resources and Environment, 2020
    Co-Authors: Yuping Tang, Jinghua Wang, Yanfang Li, Wen Ma
    Abstract:

    Four flavonol glycosides and three flavonols were isolated from the pericarp of Sophora Japonica L. and elucidated by chemical and spectral method as kaempferol 3-O-beta-rutinoside (I), rutin (II), kaempferol 3-O-beta-D-glucoside (III), quercetin 3-O-beta-D-glucoside (IV), kaempferol (V), quercetin (VI), isorhamnetin (VII). Among them, compounds I, IV and VII are reported in this species for the first time.

  • isoflavone tetraglycosides from Sophora Japonica leaves
    Journal of Natural Products, 2008
    Co-Authors: Yuping Tang, Ruolin Yang, Jinao Duan, Erxin Shang, Shulan Su, Dawei Qian
    Abstract:

    Two new isoflavone tetraglycosides (1 and 2) and six known compounds were isolated from the leaves of Sophora Japonica. The new glycosides are genistein 7-O-β-d-glucopyranoside-4′-O-(6′′′-O-α-l-rhamnopyranosyl)-β-sophoroside (1) and genistein 7-O-α-l-rhamnopyranoside-4′-O-(6′′′-O-α-l-rhamnopyranosyl)-β-sophoroside (2). The structures of compounds 1 and 2 were established primarily by NMR experiments and chemical methods, and they are the first reported naturally occurring isoflavone glycosides with four attached sugar residues.

  • a flavonol tetraglycoside from Sophora Japonica seeds
    Phytochemistry, 2003
    Co-Authors: Jinghua Wang, Yalin Wang, Yuping Tang
    Abstract:

    Abstract A flavonol tetraglycoside, kaempferol 3- O -α- l -rhamnopyranosyl(1→6)-β- d -glucopyranosyl(1→2)- β- d -glucopyranoside-7-O-α- l rhamnopyranoside, together with nine known compounds were isolated from the seeds of Sophora Japonica L. Their structures were elucidated on the basis of spectral and chemical evidence.

  • isolation and identification of antioxidants from Sophora Japonica
    Journal of Asian Natural Products Research, 2002
    Co-Authors: Yuping Tang, Yanfang Li, Jie Hu
    Abstract:

    A new flavonol triglycoside, kaempferol 3- O - f - l -rhamnopyranosyl-(1 M 6)- g - d -glucopyranosyl-(1 M 2)- g - d -glucopyranoside ( 1 ), as well as two known kaempferol 3- O -[ f - l -rhamnopyranosyl-(1 M 6)]-[ g - d -glucopyranosyl-(1 M 2)]- g - d -glucopyranoside ( 2 ) and kaempferol 3- O - g - d -glucopyranosyl-(1 M 2)- g - d -glucopyranoside-7- O - f - l -rhamnopyranoside ( 3 ), were isolated from the n -BuOH extract of the pericarps of Sophora Japonica by bioassay-guided fractionation. The structure of compound 1 was established by UV, IR, MS, and one- and two-dimensional NMR spectroscopy, including DEPT, NOESY, DQF-COSY, TOCSY, HMQC, and HMBC experiments. Compounds 1 - 3 showed antioxidative activity in DPPH and cytochrome-c assay using HL-60 cell system.

  • a new coumaronochromone from Sophora Japonica
    Journal of Asian Natural Products Research, 2002
    Co-Authors: Yuping Tang, Jie Hu, Jinghua Wang
    Abstract:

    A new coumaronochromone derivative, sophorophenolone ( 1 ), along with 13 known compounds, l -maackiain ( 2 ), medicagol ( 3 ), 7- O -methylpseudobaptigenin ( 4 ), pseudobaptigenin ( 5 ), 7,3'-di- O -methylorobol ( 6 ), genistein ( 7 ), prunetin ( 8 ), daidzein ( 9 ), formononetin ( 10 ), Di- O -methyldaidzein ( 11 ), quercetin ( 12 ), kaempferol ( 13 ) and isorhamnetin ( 14 ) were isolated from pericarps of Sophora Japonica L. The structure of compound 1 was established by UV, IR, MS, and one-dimensional and two-dimensional NMR spectroscopy, including DEPT, NOESY, 1 H- 1 H COSY, HMQC, and HMBC experiments.

Akl M. Awwad - One of the best experts on this subject based on the ideXlab platform.

  • Kinetic and Thermodynamics of Biosorption Ni(II) Ions From Electroplating Wastewater onto Sophora Japonica Seeds Powder
    2020
    Co-Authors: Akl M. Awwad, Ahmad L. Ahmad
    Abstract:

    The removal of Ni(II) ions from aqueous solutions and electroplating wastewater onto Sophora Japonica seeds powder has been studied by using batch adsorption technique. The biosorption studies were determined as a function of pH, contact time, initial metal ion concentration, biosorbent dosage and temperature. The kinetic study showed that the biosorption of the Ni(II) ions followed pseudo-second-order kinetic model. Experimental data obtained were analyzed with Langmuir and Freundlich, isotherm models and in each case the Langmuir model appears to have better regression coefficients. Thermodynamic parameters: ΔG o , ΔH o and ΔS o were calculated indicating that the biosorption of Ni(II) ions onto Sophora Japonica seeds powder was a spontaneous and endothermic process. The biosorption process was successfully applied to the treatment of an electroplating wastewater sample, where the concentration of nickel and COD were effectively reduced. The results of the study showed that Sophora Japonica seeds powder(SjsP) can be efficiently used as a low-cost and ecofriendly alternative for the removal of Ni(II) ions from aqueous solutions and electroplating wastewater.

  • Phytochemical and Spectral Studies of Synthesis sulfur Nanoparticles using Sophora Japonica Pods Extract
    Journal of Advances in Chemistry, 2015
    Co-Authors: Akl M. Awwad, Nidá M. Salem, Amany O. Abdeen
    Abstract:

    This study aims to investigate the aqueous extract of Sophora Japonica pods for the presence of various phytochemicals and to synthesize sulfur nanoparticles. The presence of various phytochemicals viz. polyphenols, alkaloids, terpenoids, flavonoids, and tannins were investigated by standard biochemical methods.  A rapid, green and novel approach for synthesis sulfur nanoparticles (SNPs) from sodium thiosulfate in the presence of Sophora Japonica pods aqueous extract in one-pot reaction at ambient temperature. The resulting sulfur nanoparticles were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results show that sulfur nanoparticles were successfully synthesized in sphere shape, and with an average particle size 5-100 nm. The effect of plant pods extract concentration on particle size of sulfur nanoparticles shows that can significantly reduce the particle size without changing the shape. The results revealed that the aqueous extract of Sophora Japonica pods act as capping, dispersing and stabilizing agent for sulfur nanoparticles. This method is a novel approach for production nanosized sulfur particles, which could be applied to prepare sulfur nanoparticles for application in antimicrobial activity, fertilizers, and plant protection.

  • Biosorption of Cu(II), Ni(II), Zn(II) and Pb(II) ions from aqueous solution by Sophora Japonica pods powder
    International Journal of Industrial Chemistry, 2015
    Co-Authors: Mohammad W. Amer, Rafat A. Ahmad, Akl M. Awwad
    Abstract:

    Background Biosorption of Cu (II), Ni(II), Zn(II) and Pb(II) ions from aqueous solutions onto Sophora Japonica pods powder has been studied using batch adsorption technique. The biosorption studies were determined as a function of pH, contact time, initial metal ion concentration, biosorbent dosage and temperature. Results The kinetic study showed that the biosorption of the Cu(II), Ni(II), Zn(II) and Pb(II) ions followed pseudo-second-order kinetic model. Experimental data obtained were analyzed with Langmuir, Freundlich, Dubinin–Radushkevich and Temkin isotherm models and in each case the Langmuir model appears to have better regression coefficients. Thermodynamic parameters: ΔG°, ΔH° and ΔS° were calculated indicating that the biosorption of Cu(II), Ni(II), Zn(II) and Pb(II) ions is spontaneous and endothermic process. Conclusions The results of the study showed that Sophora Japonica pods powder can be efficiently used as a low-cost alternative for the removal of Cu(II), Ni(II), Zn(II) and Pb(II) ions from aqueous solutions.

  • biosorption of cu ii ni ii zn ii and pb ii ions from aqueous solution by Sophora Japonica pods powder
    International Journal of Industrial Chemistry, 2015
    Co-Authors: Mohammad W. Amer, Rafat A. Ahmad, Akl M. Awwad
    Abstract:

    Background Biosorption of Cu (II), Ni(II), Zn(II) and Pb(II) ions from aqueous solutions onto Sophora Japonica pods powder has been studied using batch adsorption technique. The biosorption studies were determined as a function of pH, contact time, initial metal ion concentration, biosorbent dosage and temperature.

Yuyin Xu - One of the best experts on this subject based on the ideXlab platform.

  • effect of Sophora Japonica total flavonoids on pancreas kidney tissue morphology of streptozotocin induced diabetic mice model
    Saudi Journal of Biological Sciences, 2017
    Co-Authors: Ting Wang, Mingsan Miao, Cai-rong Li, Yan Li, Min Li, Yuyin Xu
    Abstract:

    To observe effect of Sophora Japonica total flavonoids on pancreas, kidney tissue morphology of streptozotocin-induced diabetic mice model. Mice received tail vein injection of streptozotocin (60 mg/kg) for diabetes modeling. The model mice were divided into five groups, to be respectively fed with high, middle and small doses of Sophora Japonica total flavonoids solution, metformin solution and saline of the same volume. Another blank control group was set to be fed with saline of the same volume. The mice were administered once a day for 30 consecutive days, to be euthanatized after fasting blood glucose level testing on 30th day with pancreas, kidney taken out for pathological section and microscopic examination. The mice chain streptozotocin diabetes modeling was successful, with significant pathological changes (P < 0.01) in pancreas, kidney. Compared with model group, high, middle and small doses of Sophora Japonica total flavonoids could significantly alleviate streptozotocin-induced pancreas, kidney damage (P < 0.01). Conclusion: Sophora Japonica total flavonoids can effectively alleviate pancreas, kidney injury of streptozotocin-induced diabetic mice model.

  • Effect of Sophora Japonica total flavonoids on pancreas, kidney tissue morphology of streptozotocin-induced diabetic mice model.
    Saudi Journal of Biological Sciences, 2017
    Co-Authors: Ting Wang, Mingsan Miao, Cai-rong Li, Yan Li, Min Li, Yuyin Xu
    Abstract:

    To observe effect of Sophora Japonica total flavonoids on pancreas, kidney tissue morphology of streptozotocin-induced diabetic mice model. Mice received tail vein injection of streptozotocin (60 mg/kg) for diabetes modeling. The model mice were divided into five groups, to be respectively fed with high, middle and small doses of Sophora Japonica total flavonoids solution, metformin solution and saline of the same volume. Another blank control group was set to be fed with saline of the same volume. The mice were administered once a day for 30 consecutive days, to be euthanatized after fasting blood glucose level testing on 30th day with pancreas, kidney taken out for pathological section and microscopic examination. The mice chain streptozotocin diabetes modeling was successful, with significant pathological changes (P 

Mingsan Miao - One of the best experts on this subject based on the ideXlab platform.

  • Effects of Flavonoids from Sophora Japonica Thunb on Diabetes Mellitus in Mice
    DEStech Transactions on Biology and Health, 2017
    Co-Authors: Mingsan Miao, Meng-fei Zhang, Cai-rong Li, Suxiang Feng, Xiao-yan Fang
    Abstract:

    Objective: To investigate the hypoglycemic effect of flavonoids from Sophora Japonica L. and its mechanism. Method: The model of hyperglycemia induced by streptozotocin was injected into the tail vein of the mice. The rats were fasted for 12 hours on the 11th day of injection and the fasting blood glucose. The total flavonoids of Sophorae japonicus were continuously fed for 30 days. Blood glucose and glycogen content were measured at the 10th, 20th and 30th day after administration. Take the formalin fixed pancreas, do histopathology. Result: The total flavonoids of Sophora Japonica significantly reduced the hyperglycemia of streptozotocin-induced diabetic mice, improved the shape and function of pancreatic islet cells, and played a good role in lowering blood glucose. Conclusion: Flavonoids of Sophora Japonica L. have obvious hypoglycemic effect, which can improve hyperlipidemia and kidney damage of diabetes mellitus.

  • effect of Sophora Japonica total flavonoids on pancreas kidney tissue morphology of streptozotocin induced diabetic mice model
    Saudi Journal of Biological Sciences, 2017
    Co-Authors: Ting Wang, Mingsan Miao, Cai-rong Li, Yan Li, Min Li, Yuyin Xu
    Abstract:

    To observe effect of Sophora Japonica total flavonoids on pancreas, kidney tissue morphology of streptozotocin-induced diabetic mice model. Mice received tail vein injection of streptozotocin (60 mg/kg) for diabetes modeling. The model mice were divided into five groups, to be respectively fed with high, middle and small doses of Sophora Japonica total flavonoids solution, metformin solution and saline of the same volume. Another blank control group was set to be fed with saline of the same volume. The mice were administered once a day for 30 consecutive days, to be euthanatized after fasting blood glucose level testing on 30th day with pancreas, kidney taken out for pathological section and microscopic examination. The mice chain streptozotocin diabetes modeling was successful, with significant pathological changes (P < 0.01) in pancreas, kidney. Compared with model group, high, middle and small doses of Sophora Japonica total flavonoids could significantly alleviate streptozotocin-induced pancreas, kidney damage (P < 0.01). Conclusion: Sophora Japonica total flavonoids can effectively alleviate pancreas, kidney injury of streptozotocin-induced diabetic mice model.

  • Effect of Sophora Japonica total flavonoids on pancreas, kidney tissue morphology of streptozotocin-induced diabetic mice model.
    Saudi Journal of Biological Sciences, 2017
    Co-Authors: Ting Wang, Mingsan Miao, Cai-rong Li, Yan Li, Min Li, Yuyin Xu
    Abstract:

    To observe effect of Sophora Japonica total flavonoids on pancreas, kidney tissue morphology of streptozotocin-induced diabetic mice model. Mice received tail vein injection of streptozotocin (60 mg/kg) for diabetes modeling. The model mice were divided into five groups, to be respectively fed with high, middle and small doses of Sophora Japonica total flavonoids solution, metformin solution and saline of the same volume. Another blank control group was set to be fed with saline of the same volume. The mice were administered once a day for 30 consecutive days, to be euthanatized after fasting blood glucose level testing on 30th day with pancreas, kidney taken out for pathological section and microscopic examination. The mice chain streptozotocin diabetes modeling was successful, with significant pathological changes (P 

  • effect of Sophora Japonica total flavonoids on mouse models of hyperglycemia and diabetes model
    Applied Mechanics and Materials, 2014
    Co-Authors: Mingsan Miao, Bo Lin Cheng, Na Jiang
    Abstract:

    Objective: To investigate the effects of Sophora Japonica total flavonoids hyperglycemia and diabetes in mice models. Methods: intraperitoneal injection of epinephrine, intravenous injection of freshly prepared alloxan or intravenous injection of streptozotocin, alloxan build adrenaline or hyperglycemia model streptozotocin diabetic model. Glucose values ​​were selected for each experiment> 11.1mmol / L, with a significantly more drinking, eating, and more urinary symptoms in mice 60, according to blood glucose levels were randomly divided into six groups, namely large, medium and small doses of Sophora Japonica total flavonoids group, metformin group, the control group and model group. And were fed the appropriate medication, model group and the control group fed with the same volume of saline solution. Results: Sophora Japonica total flavonoids can significantly reduce the adrenaline and alloxan mice with high blood sugar glucose levels, improve liver glycogen content; can significantly reduce the streptozotocin-diabetic mouse model of blood glucose levels and improve hepatic glycogen,can significantly improve the streptozotocin-induced islet cell damage. Conclusion: Sophora Japonica total flavonoids mouse model of hyperglycemia and diabetes mellitus have a better hypoglycemic effect of its hypoglycemic effect and promote glycogen synthesis, reduce islet cell damage.

Jinghua Wang - One of the best experts on this subject based on the ideXlab platform.

  • Flavonols and flavonol glycosides from the pericarp of Sophora Japonica L.
    Journal of Plant Resources and Environment, 2020
    Co-Authors: Yuping Tang, Jinghua Wang, Yanfang Li, Wen Ma
    Abstract:

    Four flavonol glycosides and three flavonols were isolated from the pericarp of Sophora Japonica L. and elucidated by chemical and spectral method as kaempferol 3-O-beta-rutinoside (I), rutin (II), kaempferol 3-O-beta-D-glucoside (III), quercetin 3-O-beta-D-glucoside (IV), kaempferol (V), quercetin (VI), isorhamnetin (VII). Among them, compounds I, IV and VII are reported in this species for the first time.

  • a flavonol tetraglycoside from Sophora Japonica seeds
    Phytochemistry, 2003
    Co-Authors: Jinghua Wang, Yalin Wang, Yuping Tang
    Abstract:

    Abstract A flavonol tetraglycoside, kaempferol 3- O -α- l -rhamnopyranosyl(1→6)-β- d -glucopyranosyl(1→2)- β- d -glucopyranoside-7-O-α- l rhamnopyranoside, together with nine known compounds were isolated from the seeds of Sophora Japonica L. Their structures were elucidated on the basis of spectral and chemical evidence.

  • a new coumaronochromone from Sophora Japonica
    Journal of Asian Natural Products Research, 2002
    Co-Authors: Yuping Tang, Jie Hu, Jinghua Wang
    Abstract:

    A new coumaronochromone derivative, sophorophenolone ( 1 ), along with 13 known compounds, l -maackiain ( 2 ), medicagol ( 3 ), 7- O -methylpseudobaptigenin ( 4 ), pseudobaptigenin ( 5 ), 7,3'-di- O -methylorobol ( 6 ), genistein ( 7 ), prunetin ( 8 ), daidzein ( 9 ), formononetin ( 10 ), Di- O -methyldaidzein ( 11 ), quercetin ( 12 ), kaempferol ( 13 ) and isorhamnetin ( 14 ) were isolated from pericarps of Sophora Japonica L. The structure of compound 1 was established by UV, IR, MS, and one-dimensional and two-dimensional NMR spectroscopy, including DEPT, NOESY, 1 H- 1 H COSY, HMQC, and HMBC experiments.

  • four new isoflavone triglycosides from Sophora Japonica
    Journal of Natural Products, 2001
    Co-Authors: Yuping Tang, Jinghua Wang, Shufei Zhuang
    Abstract:

    Four new isoflavone triglycosides, genistein 7-O-β-d-glucopyranoside-4‘-O-[(α-l-rhamnopyranosyl)-(1→2)-β-d-glucopyranoside] (1), genistein 7-O-β-d-glucopyranoside-4‘-O-[(β-d-glucopyranosyl)-(1→2)-β-d-glucopyranoside] (2), genistein 7-O-α-l-rhamnopyranoside-4‘-O-[(α-l-rhamnopyranosyl)-(1→2)-β-d-glucopyranoside] (3), and genistein 7-O-α-l-rhamnopyranoside-4‘-O-[(β-d-glucopyranosyl)-(1→2)-β-d-glucopyranoside] (4), together with nine known compounds, namely, genistein 7-O-β-d-glucopyranoside-4‘-O-β-d-glucopyranoside, Sophorabioside, prunetin 4‘-O-β-d-glucopyranoside, sophororicoside, genistin, rutin, kaempferol 3-O-β-rutinoside, quercetin 3-O-β-d-glucopyranoside, and kaempferol 3-O-β-d-glucopyranoside, were isolated from the pericarps of Sophora Japonica. The structures of 1−4 were determined by spectroscopic methods.