The Experts below are selected from a list of 1050 Experts worldwide ranked by ideXlab platform

Benjamin T. Brown - One of the best experts on this subject based on the ideXlab platform.

  • A systematic literature review of Spinal Brace/orthosis treatment for adults with scoliosis between 1967 and 2018: clinical outcomes and harms data.
    BMC Musculoskeletal Disorders, 2020
    Co-Authors: Jeb Mcaviney, Johanna Mee, Azharuddin Fazalbhoy, Juan Du Plessis, Benjamin T. Brown
    Abstract:

    There is a paucity of literature regarding the conservative management of adult scoliosis. The authors review and summarize the literature from 1967 to 2018 on the clinical outcomes of Spinal Brace/orthosis use in this subgroup of the population. CINAHL, Embase, CENTRAL, PubMed and PEDro were searched from database inception to the 30th of October, 2018. A combination of medical subject heading terms and keywords pertaining to three core concepts (adult, scoliosis, and Braces/orthoses) were used in the search. Studies were included if A) clinical outcomes were collected from B) participants ≥18 years C) receiving Spinal Brace/orthosis treatment for D) primary degenerative (de novo) scoliosis or progressive idiopathic scoliosis. A step-wise screening process was employed which involved a title and abstract screen for relevancy followed by a full text eligibility appraisal by two authors. Data were extracted, and a risk of bias assessment was performed on the included cohort studies using the Newcastle-Ottawa Scale. Given the overall level and quality of the available evidence, conclusions were drawn based on a qualitative summary of the evidence. Ten studies (four case reports and six cohort studies) were included which detailed the clinical outcomes of soft (2 studies) or rigid bracing (8 studies), used as a standalone therapy or in combination with physiotherapy/rehabilitation, in 339 adults with various types of scoliosis. Most studies included female participants only. Commonly reported outcomes were pain (7 studies), function (3 studies) and Cobb angles (3 studies), with follow-up times ranging from 2 days to 17 years. Brace wear prescriptions ranged from 2 to 23 h per day, and there was mixed Brace-compliance reported. Most studies reported modest or significant reduction in pain and improvement in function at follow-up. There were mixed findings with regards to Cobb angle changes in response to bracing. Participants from one study noted discomfort associated with bracing. Each of the six cohort studies demonstrated a high risk of bias. There is evidence to suggest that Spinal Brace/orthosis treatment may have a positive short – medium term influence on pain and function in adults with either progressive primary (de novo) degenerative scoliosis or progressive idiopathic scoliosis. At this point in time the evidence is of low quality and has been focused primarily on female patients with thoracolumbar and lumbar curves. More granular statements regarding the efficacy of different Brace types or manufacturers, or the effect of this therapy on different curve types cannot be determined based on the current literature. Properly constructed prospective trials are required to better understand the efficacy of bracing in adult scoliosis.

  • a systematic literature review of Spinal Brace orthosis treatment for adults with scoliosis between 1967 and 2018 clinical outcomes and harms data
    BMC Musculoskeletal Disorders, 2020
    Co-Authors: Jeb Mcaviney, Johanna Mee, Azharuddin Fazalbhoy, Juan Du Plessis, Benjamin T. Brown
    Abstract:

    There is a paucity of literature regarding the conservative management of adult scoliosis. The authors review and summarize the literature from 1967 to 2018 on the clinical outcomes of Spinal Brace/orthosis use in this subgroup of the population. CINAHL, Embase, CENTRAL, PubMed and PEDro were searched from database inception to the 30th of October, 2018. A combination of medical subject heading terms and keywords pertaining to three core concepts (adult, scoliosis, and Braces/orthoses) were used in the search. Studies were included if A) clinical outcomes were collected from B) participants ≥18 years C) receiving Spinal Brace/orthosis treatment for D) primary degenerative (de novo) scoliosis or progressive idiopathic scoliosis. A step-wise screening process was employed which involved a title and abstract screen for relevancy followed by a full text eligibility appraisal by two authors. Data were extracted, and a risk of bias assessment was performed on the included cohort studies using the Newcastle-Ottawa Scale. Given the overall level and quality of the available evidence, conclusions were drawn based on a qualitative summary of the evidence. Ten studies (four case reports and six cohort studies) were included which detailed the clinical outcomes of soft (2 studies) or rigid bracing (8 studies), used as a standalone therapy or in combination with physiotherapy/rehabilitation, in 339 adults with various types of scoliosis. Most studies included female participants only. Commonly reported outcomes were pain (7 studies), function (3 studies) and Cobb angles (3 studies), with follow-up times ranging from 2 days to 17 years. Brace wear prescriptions ranged from 2 to 23 h per day, and there was mixed Brace-compliance reported. Most studies reported modest or significant reduction in pain and improvement in function at follow-up. There were mixed findings with regards to Cobb angle changes in response to bracing. Participants from one study noted discomfort associated with bracing. Each of the six cohort studies demonstrated a high risk of bias. There is evidence to suggest that Spinal Brace/orthosis treatment may have a positive short – medium term influence on pain and function in adults with either progressive primary (de novo) degenerative scoliosis or progressive idiopathic scoliosis. At this point in time the evidence is of low quality and has been focused primarily on female patients with thoracolumbar and lumbar curves. More granular statements regarding the efficacy of different Brace types or manufacturers, or the effect of this therapy on different curve types cannot be determined based on the current literature. Properly constructed prospective trials are required to better understand the efficacy of bracing in adult scoliosis.

Ferrari Adriano - One of the best experts on this subject based on the ideXlab platform.

Adriano Ferrari - One of the best experts on this subject based on the ideXlab platform.

  • Spinal bracing and lung function in type-2 Spinal muscular atrophy.
    European Journal of Physical and Rehabilitation Medicine, 2019
    Co-Authors: Chiara Di Pede, Eleonora Salamon, Matteo Motta, Caterina Agosto, Franca Benini, Adriano Ferrari
    Abstract:

    Background Respiratory muscle weakness associated with scoliosis in type-2 Spinal muscular atrophy (SMA) leads to respiratory impairment. Spinal Brace, generally utilized to slow scoliosis progression and support sitting, could worsen lung function and hamper cough maneuvers. Case series Six home-treated type-2 SMA children (aged 6-15 years, subtype 2.1-2.5) were assessed to evaluate time-dependent influence of "static-balanced Brace" on pulmonary function. Lung function tests, including peak expiratory flow (PEF), peak cough flow (PCF), maximal static inspiratory pressure (MIP), maximal static expiratory pressure (MEP), forced vital capacity (FVC), were performed. PEF, MEP, FVC parameters were higher in tests after wearing Braces three-hours, PCF slightly higher and MIP slightly lower compared to upon awakening values. Clinical rehabilitation impact "Static-balanced Brace" did not impair lung function in our sample of six type-2 SMA children; in addition, it seemed to support cough maneuvers. Double assessment is determinant for decisions concerning use/non-use of Brace differently from the usual one time evaluation procedure (base level compared to level wearing Brace).

Gunnar Hägglund - One of the best experts on this subject based on the ideXlab platform.

  • Refugee/immigrant children with cerebral palsy in the Swedish health care organization
    Lakartidningen, 2019
    Co-Authors: Lena Westbom, Gunnar Hägglund
    Abstract:

    Cerebral palsy (CP) is present in about 200 children per birth-year cohort in Sweden. From 2001 to 2016, the annual number of immigrants to Sweden with CP enrolled at the (re)habilitation services increased from less than ten to 40-90 individuals per year; about 70 % came to Sweden as refugees. At a group level, children with CP born abroad had greater functional impairment than children born in Sweden, based on information in the Swedish national surveillance program and health care quality register for CP (CPUP). There was a significantly higher prevalence of CP, a greater proportion of children with bilateral spastic CP, and a lower proportion with unilateral spastic CP among the immigrants. The proportion of children in each gross motor function level treated with orthoses, standing frames, Spinal Brace or botulinum toxin was the same regardless of whether the child was born in Sweden or abroad. In summary, the (re)habilitation services and orthopedics have managed to provide a relatively large group of immigrants/refugees with CP with equal treatment compared to children born in Sweden.

  • Ökad inflyttning av barn med cerebral pares - Likvärdig behandling har getts till utrikes och inrikes födda
    Läkartidningen, 2019
    Co-Authors: Lena Westbom, Gunnar Hägglund
    Abstract:

    Cerebral palsy (CP) is present in about 200 children per birth-year cohort in Sweden. From 2001 to 2016, the annual number of immigrants to Sweden with CP enrolled at the (re)habilitation services increased from less than ten to 40-90 individuals per year; about 70 % came to Sweden as refugees. At a group level, children with CP born abroad had greater functional impairment than children born in Sweden, based on information in the Swedish national surveillance program and health care quality register for CP (CPUP). There was a significantly higher prevalence of CP, a greater proportion of children with bilateral spastic CP, and a lower proportion with unilateral spastic CP among the immigrants. The proportion of children in each gross motor function level treated with orthoses, standing frames, Spinal Brace or botulinum toxin was the same regardless of whether the child was born in Sweden or abroad. In summary, the (re)habilitation services and orthopedics have managed to provide a relatively large group of immigrants/refugees with CP with equal treatment compared to children born in Sweden. (Less)

Kanakeya Bachha Reddy - One of the best experts on this subject based on the ideXlab platform.

  • Pott’s paraplegia secondary to Scrofuloderma is a rare association
    Spinal Cord, 2013
    Co-Authors: Rajesh Kumar Kanojia, M Kalra, Atul Sareen, Kanakeya Bachha Reddy
    Abstract:

    Study design: Spinal tuberculosis as all other osteoarticular tuberculosis occurs as a result of hematogenous dissemination of Mycobacterium tuberculosis from a primarily infected visceral focus mainly lungs, but Pott’s paraplegia occurring secondarily to Scrofuloderma has not been reported till date. Purpose: To document such an association of Pott’s paraplegia and Scrofuloderma. Methods: A 29-year-old female presented to us with low backache and paraplegia of 1 month duration. Clinical examination showed multiple healed Scrofuloderma lesions over sterum and neck ( Figure 1 ). Magnetic resonance imaging (Figure 4), computed tomography (Figure 3) and X-ray ( Figure 2 ) showed Pott’s spine involving dorsal vertebrae (D8–10) with pre and paravetebral abscess with intraSpinal extension. She was treated by minimally invasive surgery to drain pus and granulation tissue by resecting transverse process of D9 vertebra. Drained material was sent for histopathological examination, Zielh-neelsen (ZN) staining, culture and sensitivity for M. tuberculosis . Patient completely recovered neurologically after 1 month of surgery. Figure 1 Clinical photographs showing multiple healed Scrofuloderma lesions over neck and sternum. Figure 2 X-ray dorso lumbar spine antero-posterior view showing lateral translation of D9 over D10 vertebra. Results: Patient completely recovered neurologically after surgery and is presently on multidrug chemotherapy and Spinal Brace. Conclusions: Pott’s paraplegia can occur secondary to Scrofuloderma and it can be managed by multidrug antitubercular therapy and minimally invasive surgical procedure.

  • Pott's paraplegia secondary to Scrofuloderma is a rare association.
    Spinal Cord, 2013
    Co-Authors: Rajesh Kumar Kanojia, M Kalra, Atul Sareen, Kanakeya Bachha Reddy
    Abstract:

    Spinal tuberculosis as all other osteoarticular tuberculosis occurs as a result of hematogenous dissemination of Mycobacterium tuberculosis from a primarily infected visceral focus mainly lungs, but Pott’s paraplegia occurring secondarily to Scrofuloderma has not been reported till date. To document such an association of Pott’s paraplegia and Scrofuloderma. A 29-year-old female presented to us with low backache and paraplegia of 1 month duration. Clinical examination showed multiple healed Scrofuloderma lesions over sterum and neck (Figure 1). Magnetic resonance imaging (Figure 4), computed tomography (Figure 3) and X-ray (Figure 2) showed Pott’s spine involving dorsal vertebrae (D8–10) with pre and paravetebral abscess with intraSpinal extension. She was treated by minimally invasive surgery to drain pus and granulation tissue by resecting transverse process of D9 vertebra. Drained material was sent for histopathological examination, Zielh-neelsen (ZN) staining, culture and sensitivity for M. tuberculosis. Patient completely recovered neurologically after 1 month of surgery. Patient completely recovered neurologically after surgery and is presently on multidrug chemotherapy and Spinal Brace. Pott’s paraplegia can occur secondary to Scrofuloderma and it can be managed by multidrug antitubercular therapy and minimally invasive surgical procedure.