The Experts below are selected from a list of 30 Experts worldwide ranked by ideXlab platform

Deng Lixin - One of the best experts on this subject based on the ideXlab platform.

  • diagnosis and treatment of canine Spleen Hematoma
    China Animal Husbandry & Veterinary Medicine, 2009
    Co-Authors: Deng Lixin
    Abstract:

    Spleen Hematoma is caused by rupture of Spleen vessel and blood entering into integument.The disease has a low morbidity,which is hard to diagnosed and treated.In this article,the diagnosis and treatment of canine Spleen Hematoma were analyzed and generalized,especially the operation was discussed for providing theories and directive meanings to diagnose and treat this disease.

Antonella Repetto - One of the best experts on this subject based on the ideXlab platform.

  • Absidia Corymbiferain an immune competent accident victim with multiple abdominal injuries: case report
    BMC Infectious Diseases, 2007
    Co-Authors: Rita Belfiori, Adelmo Terenzi, Laura Marchesini, Antonella Repetto
    Abstract:

    Background We report a case of mucormycosis in a healthy 17-year-old accident victim with multiple abdominal injuries which was caused by infection with Absidia Corymbifera , a ubiquitous saphrophyte in the ground. Case presentation The patient was admitted to hospital with massive abdominal trauma. During an 8-hour emergency operation he received transfusions of compacted red blood cells, plasma, platelets and hemagel. He developed a crush syndrome with acute renal failure, resolved with extra-corporeal dialysis and had to undergo splenectomy because of Spleen Hematoma. As wound secretion and central venous catheter (CVC) blood cultures and drainage fluid were positive for Enterococcus Faecium , Providentia Rettgeri , Hafnia Alvei and Candida Albicans , tecoplanin, metronidazole, imipenem, and flucanozole were administered. Although the CVC was changed high fever persisted and discharge continued from the large abdominal wound. Repeated tampons in different sections and wound secretion smears were positive for A. corymbifera . Flucanozole was stopped and liposomal amphotericin (Ambisome; 5 mg/Kg i.v.) given for over 3 months. The patient improved; fever gradually disappeared. After 8 days, tampons and wound secretion smears were negative for A. corymbifera . No other fungal infections developed. Drainage fluid was later positive for tecoplanin-resistant E. faecium and Pseudomonas Aeroginosa responding only to meropenem and ciprofloxacin. Abdominal computerized tomography visualized fluid accumulation around the iliac-femoral bypass. Abcess was ruled out when scintigraphy showed no tracer uptake. The lesion was drained. Drainage fluid cultures were negative for bacteria and fungi. Fluid accumulation gradually disappeared with prolonged antibiotic and antifungal therapy. One year after the accident the patient is in good health, with normal quality of life. Conclusion Successful outcome was due to early, specific antifungal therapy, at sufficiently high dosage which was prolonged for an adequate period of time. Early diagnosis of mucormycosis is essential for efficacious anti-fungal treatment and prevention of irreversible spread of mucormycosis to vital organs. It presupposes awareness that A. corymbifera infection can develop in healthy individuals who are stressed and traumatized through skin-ground contact in accidents.

Rita Belfiori - One of the best experts on this subject based on the ideXlab platform.

  • Absidia Corymbiferain an immune competent accident victim with multiple abdominal injuries: case report
    BMC Infectious Diseases, 2007
    Co-Authors: Rita Belfiori, Adelmo Terenzi, Laura Marchesini, Antonella Repetto
    Abstract:

    Background We report a case of mucormycosis in a healthy 17-year-old accident victim with multiple abdominal injuries which was caused by infection with Absidia Corymbifera , a ubiquitous saphrophyte in the ground. Case presentation The patient was admitted to hospital with massive abdominal trauma. During an 8-hour emergency operation he received transfusions of compacted red blood cells, plasma, platelets and hemagel. He developed a crush syndrome with acute renal failure, resolved with extra-corporeal dialysis and had to undergo splenectomy because of Spleen Hematoma. As wound secretion and central venous catheter (CVC) blood cultures and drainage fluid were positive for Enterococcus Faecium , Providentia Rettgeri , Hafnia Alvei and Candida Albicans , tecoplanin, metronidazole, imipenem, and flucanozole were administered. Although the CVC was changed high fever persisted and discharge continued from the large abdominal wound. Repeated tampons in different sections and wound secretion smears were positive for A. corymbifera . Flucanozole was stopped and liposomal amphotericin (Ambisome; 5 mg/Kg i.v.) given for over 3 months. The patient improved; fever gradually disappeared. After 8 days, tampons and wound secretion smears were negative for A. corymbifera . No other fungal infections developed. Drainage fluid was later positive for tecoplanin-resistant E. faecium and Pseudomonas Aeroginosa responding only to meropenem and ciprofloxacin. Abdominal computerized tomography visualized fluid accumulation around the iliac-femoral bypass. Abcess was ruled out when scintigraphy showed no tracer uptake. The lesion was drained. Drainage fluid cultures were negative for bacteria and fungi. Fluid accumulation gradually disappeared with prolonged antibiotic and antifungal therapy. One year after the accident the patient is in good health, with normal quality of life. Conclusion Successful outcome was due to early, specific antifungal therapy, at sufficiently high dosage which was prolonged for an adequate period of time. Early diagnosis of mucormycosis is essential for efficacious anti-fungal treatment and prevention of irreversible spread of mucormycosis to vital organs. It presupposes awareness that A. corymbifera infection can develop in healthy individuals who are stressed and traumatized through skin-ground contact in accidents.

Hiroshi Itoh - One of the best experts on this subject based on the ideXlab platform.

  • Investigation of serum concentrations and immunohistochemical localization of α1-acid glycoprotein in tumor dogs
    Veterinary Research Communications, 2011
    Co-Authors: Masashi Yuki, Noboru Machida, Takayuki Sawano, Hiroshi Itoh
    Abstract:

    The purpose of this study was to measure the dynamics of serum α1-acid glycoprotein (AGP) concentration in dogs with various tumors, and to investigate the localization of AGP in some tissues using immunohistochemical staining. Sera were obtained from 171 dogs bearing tumors of various types. Serum AGP concentration was measured by single radial immunodiffusion. Tumors occurring in the liver and Spleen were also investigated immunohistochemically using anti-canine AGP antibody. Mean serum AGP levels were 749 ± 602 mg/L in dogs with carcinoma ( n  = 39), 1,014 ± 971 mg/L with sarcoma ( n  = 18), and 887 ± 935 mg/L with round cell tumors ( n  = 46), all significantly higher than serum AGP level in healthy dogs ( n  = 137, 364 ± 106 mg/L). Mean serum AGP levels were significantly higher than in healthy dogs in complex mammary gland carcinoma ( n  = 5, 876 ± 721 mg/L), malignant melanoma ( n  = 7, 1,010 ± 821 mg/L), and hepatocellular carcinoma ( n  = 5, 936 ± 741 mg/L) among carcinomas, hemangiosarcoma ( n  = 5, 1,740 ± 1,323 mg/L) among sarcomas, and lymphoma ( n  = 19, 1,072 ± 965 mg/L) and histiocytic tumor ( n  = 6, 1,800 ± 1,387 mg/L) among round cell tumors. In an immunohistochemical investigation of AGP localization, both weak and strong staining for anti-AGP antibody were seen in hepatic tissue in dogs with primary non-tumorous lesions originating in the Spleen (Hematoma) and elevated serum AGP, but all tumor tissue in the Spleen was negative. Among dogs with primary tumor lesions of the Spleen (hemangiosarcoma) and elevated serum AGP levels, both weak, moderate and strong staining for anti-AGP antibody were seen in hepatic tissue, while strong positive staining was apparent in all tumorous tissue from the Spleen. In primary tumor lesions in the liver (hepatocellular carcinoma), both moderate and strong staining for anti-AGP antibody were seen in normal hepatic tissue, and both weak, moderate and strong staining were seen in tumor tissues of the liver. AGP levels thus appear to be elevated in dogs with carcinomas, sarcomas, and round cell tumors. With some of these malignant tumors, localization of AGP in tumor tissue was seen.

Kipshidze Nn - One of the best experts on this subject based on the ideXlab platform.

  • Diagnostic possibilities of multilayer computer tomography in blunt abdominal trauma
    Georgian medical news, 2011
    Co-Authors: Urushadze Op, Tokhadze Lt, Kipshidze Nn
    Abstract:

    The purpose of our study was to determine MDCT diagnostic possibility in blunt abdominal trauma. Our work was based on MDCT results of 84 blunt abdominal trauma patients with stable hemodynamic status (28 (33.3%) female and 56 (66.6%) male). Age ranges from 17 up to 64 years. The CT scan showed obvious organ and system injuries in 82 poly-trauma patients. Injuries of craniocerebral region, also of facial bones, chest and spine were determined in two patients; in one of which, however, it was not possible to differentiate subcapsular Spleen Hematoma accurately because of left upper joint metallic holder artifacts. In second patient the liver injury was accurately diagnosed, but there were visualization problems caused by the massive retroperitoneal Hematoma from right adrenal gland injury. The investigation showed that sensitivity of CT scan data was 98%, specificity-97% and accuracy rate-98%. All above mentioned clearly states the importance of MDCT in the emergency department. MDCT ensures precise diagnosis in maximally short period of time and thereby helps to choose proper treatment and decreases post-traumatic complications.