The Experts below are selected from a list of 291 Experts worldwide ranked by ideXlab platform

Shijun Zhang - One of the best experts on this subject based on the ideXlab platform.

  • Acupuncture for serum uric acid in patients with asymptomatic hyperuricemia: A randomized, double-blind, placebo-controlled trial
    International Journal of Cardiology, 2017
    Co-Authors: Yingjuan Huang, Jun Meng, Ting Xiang, Zexiong Chen, Xin Zhou, Bi‐yu Xu, Yingzi Wu, Shijun Zhang
    Abstract:

    Abstract Background Hyperuricemia (HUA) is the most common disease associated with cardiovascular disease, metabolic syndrome, hypertension, and kidney disease. The objective of the current study was to evaluate the preliminary efficacy, mechanism, and safety of acupuncture on serum uric acid in patients with asymptomatic HUA. Methods A randomized, placebo-controlled trial among 123 patients with asymptomatic HUA was conducted. The acupoints used in the acupuncture group were bilateral Five Shu in Spleen Meridian . Each participant received the intervention once daily for 10 consecutive days. The sham group received the same treatment duration on the same acupoints by the Park Sham Device. All patients underwent measurements of serum or urine creatinine, uric acid, serum lipid profiles, fasting plasma glucose, HbA1c, xanthine oxidase (XOD) and urate-anion exchanger (URAT-1). Results At the end of the intervention, the individuals in the acupuncture group were found to have significantly less levels of serum uric acid than those in the sham group [(453±65 vs. 528±81) μmol/L, p p p Conclusions Acupuncture on Five Shu in Spleen Meridian appeared to be safe and efficacious for decreasing serum uric acid in a Chinese HUA patient population. The mechanism might be associated with the decrease level of enzyme URAT-1. Chinese clinical trial registration ChiCTR-TRC-13004122

  • acupuncture of the five shu acupoints in Spleen Meridian to lower blood uric acid level
    Annals of palliative medicine, 2014
    Co-Authors: Jun Meng, Ting Xiang, Zexiong Chen, Shijun Zhang
    Abstract:

    Background: Based on the principle of “Spleen governing transportation and transformation”, we have found that acupuncture of the Five Shu Acupoints in Spleen Meridian can remarkably lower the blood uric acid levels in patients with primary hyperuricemia. Objective: To explore the clinical efficacy of the acupuncture of the Five Shu Acupoints in Spleen Meridian in reducing the blood uric acid level and its relevant mechanism Methods: A total of 32 patients with primary hyperuricemia were enrolled in this study. They were allowed to have free access to diets. The initial treatment for the concomitant diseases (but not including the therapy that might affect uric acid metabolism) was kept unchanged. The observation was formally initiated at 8:00 am on day 1. Acupuncture was not performed within the 48 hours, and only the 24-hour urine volume was recorded. The urine uric acid concentration and urinary creatinine concentration were measured from 25 to 48 hours. On the 46th hour, venous blood samples were collected to detect blood uric acid and creatinine concentrations. After the 48th hour, the patients received acupuncture of the Five Shu Acupoints in Spleen Meridian each morning. Once Qi was encountered, retain the needle for 30 min. The acupuncture was performed once daily for ten consecutive days. The 24-hour urine volume was recorded daily, and the fasting indicators were detected on the morning of the 11th day. Results: After the acupuncture, the blood uric acid level significantly decreased in patients with increased production (overproduction) of uric acid, decreased excretion (underexcretion) of uric acid, and mixed type (all P<0.01). In the underexcretion type, the urine uric acid concentration significantly increased after the treatment (P<0.01). After the acupuncture, the fraction excretion of uric acid (FEUA) significantly increased in the underexcretion type and mixed type (P<0.01) and decreased in the overproduction type (P<0.01). After the acupuncture, the serum uric acid concentration decreased by 16.32-18.29% whereas the 24-hour urine volume increased by 24.22-29.32%. Conclusions: Acupuncture of the Five Shu Acupoints in Spleen Meridian can lower the blood uric acid levels by promoting uric acid excretion the and increasing urine volume.

  • Acupuncture of the Five Shu Acupoints in Spleen Meridian to lower blood uric acid level
    Annals of palliative medicine, 2014
    Co-Authors: Jun Meng, Ting Xiang, Zexiong Chen, Shijun Zhang
    Abstract:

    Background: Based on the principle of “Spleen governing transportation and transformation”, we have found that acupuncture of the Five Shu Acupoints in Spleen Meridian can remarkably lower the blood uric acid levels in patients with primary hyperuricemia. Objective: To explore the clinical efficacy of the acupuncture of the Five Shu Acupoints in Spleen Meridian in reducing the blood uric acid level and its relevant mechanism Methods: A total of 32 patients with primary hyperuricemia were enrolled in this study. They were allowed to have free access to diets. The initial treatment for the concomitant diseases (but not including the therapy that might affect uric acid metabolism) was kept unchanged. The observation was formally initiated at 8:00 am on day 1. Acupuncture was not performed within the 48 hours, and only the 24-hour urine volume was recorded. The urine uric acid concentration and urinary creatinine concentration were measured from 25 to 48 hours. On the 46th hour, venous blood samples were collected to detect blood uric acid and creatinine concentrations. After the 48th hour, the patients received acupuncture of the Five Shu Acupoints in Spleen Meridian each morning. Once Qi was encountered, retain the needle for 30 min. The acupuncture was performed once daily for ten consecutive days. The 24-hour urine volume was recorded daily, and the fasting indicators were detected on the morning of the 11th day. Results: After the acupuncture, the blood uric acid level significantly decreased in patients with increased production (overproduction) of uric acid, decreased excretion (underexcretion) of uric acid, and mixed type (all P

Yu-chuen Huang - One of the best experts on this subject based on the ideXlab platform.

  • Safe needling depths of upper back acupoints in children: a retrospective study
    BMC Complementary and Alternative Medicine, 2016
    Co-Authors: Yi-chun Ma, Ching-tien Peng, Yu-chuen Huang
    Abstract:

    Background Acupuncture is applied for treating numerous conditions in children, but few studies have examined the safe needling depth of acupoints in the pediatric population. In this study, we investigated the depths to which acupuncture needles can be inserted safely in the upper back acupoints of children and the variations in safe depth according to sex, age, weight, and body mass index (BMI). Methods We retrospectively studied computed tomography (CT) images of patients aged 4 to 18 years who underwent chest CT at China Medical University Hospital between December 2004 and May 2013. The safe depths of 23 upper back acupoints in the Governor Vessel (GV), Bladder Meridian (BL), Small Intestine Meridian (SI), Gallbladder Meridian (GB) and Spleen Meridian (SP) were measured directly from the CT images. The relationships between the safe depths of these acupoints and sex, age, body weight, and BMI were analyzed. Results The results indicated significant differences in safe needling depth between boys and girls in most upper back acupoints, except at BL42, BL44, BL45, BL46, GB21 and SP21. Safe depths differed significantly depending on age ( p  

  • Safe needling depths of upper back acupoints in children: a retrospective study
    BMC Complementary and Alternative Medicine, 2016
    Co-Authors: Yi-chun Ma, Ching-tien Peng, Yu-chuen Huang
    Abstract:

    Acupuncture is applied for treating numerous conditions in children, but few studies have examined the safe needling depth of acupoints in the pediatric population. In this study, we investigated the depths to which acupuncture needles can be inserted safely in the upper back acupoints of children and the variations in safe depth according to sex, age, weight, and body mass index (BMI). We retrospectively studied computed tomography (CT) images of patients aged 4 to 18 years who underwent chest CT at China Medical University Hospital between December 2004 and May 2013. The safe depths of 23 upper back acupoints in the Governor Vessel (GV), Bladder Meridian (BL), Small Intestine Meridian (SI), Gallbladder Meridian (GB) and Spleen Meridian (SP) were measured directly from the CT images. The relationships between the safe depths of these acupoints and sex, age, body weight, and BMI were analyzed. The results indicated significant differences in safe needling depth between boys and girls in most upper back acupoints, except at BL42, BL44, BL45, BL46, GB21 and SP21. Safe depths differed significantly depending on age (p 

  • The Depths from Skin to the Major Organs at Chest Acupoints of Pediatric Patients
    Evidence-based Complementary and Alternative Medicine, 2015
    Co-Authors: Yi-chun Ma, Ching-tien Peng, Yu-chuen Huang
    Abstract:

    Background. Acupuncture is applied to treat numerous diseases in pediatric patients. Few reports have been published on the depth to which it is safe to insert needle acupoints in pediatric patients. We evaluated the depths to which acupuncture needles can be inserted safely in chest acupoints in pediatric patients and the variations in safe depth according to sex, age, body weight, and body mass index (BMI). Methods. We retrospectively studied computed tomography (CT) images of pediatric patients aged 4 to 18 years who had undergone chest CT at China Medical University Hospital from December 2004 to May 2013. The safe depth of chest acupoints was directly measured from the CT images. The relationships between the safe depth of these acupoints and sex, age, body weight, and BMI were analyzed. Results. The results demonstrated significant differences in depth among boys and girls at KI25 (kidney Meridian), ST16 (stomach Meridian), ST18, SP17 (Spleen Meridian), SP19, SP20, PC1 (pericardium Meridian), LU2 (lung Meridian), and GB22 (gallbladder Meridian). Safe depth significantly differed among the age groups (P < 0.001), weight groups (P < 0.05), and BMI groups (P < 0.05). Conclusion. Physicians should focus on large variations in needle depth during acupuncture for achieving optimal therapeutic effect and preventing complications.

Jun Meng - One of the best experts on this subject based on the ideXlab platform.

  • Acupuncture for serum uric acid in patients with asymptomatic hyperuricemia: A randomized, double-blind, placebo-controlled trial
    International Journal of Cardiology, 2017
    Co-Authors: Yingjuan Huang, Jun Meng, Ting Xiang, Zexiong Chen, Xin Zhou, Bi‐yu Xu, Yingzi Wu, Shijun Zhang
    Abstract:

    Abstract Background Hyperuricemia (HUA) is the most common disease associated with cardiovascular disease, metabolic syndrome, hypertension, and kidney disease. The objective of the current study was to evaluate the preliminary efficacy, mechanism, and safety of acupuncture on serum uric acid in patients with asymptomatic HUA. Methods A randomized, placebo-controlled trial among 123 patients with asymptomatic HUA was conducted. The acupoints used in the acupuncture group were bilateral Five Shu in Spleen Meridian . Each participant received the intervention once daily for 10 consecutive days. The sham group received the same treatment duration on the same acupoints by the Park Sham Device. All patients underwent measurements of serum or urine creatinine, uric acid, serum lipid profiles, fasting plasma glucose, HbA1c, xanthine oxidase (XOD) and urate-anion exchanger (URAT-1). Results At the end of the intervention, the individuals in the acupuncture group were found to have significantly less levels of serum uric acid than those in the sham group [(453±65 vs. 528±81) μmol/L, p p p Conclusions Acupuncture on Five Shu in Spleen Meridian appeared to be safe and efficacious for decreasing serum uric acid in a Chinese HUA patient population. The mechanism might be associated with the decrease level of enzyme URAT-1. Chinese clinical trial registration ChiCTR-TRC-13004122

  • acupuncture of the five shu acupoints in Spleen Meridian to lower blood uric acid level
    Annals of palliative medicine, 2014
    Co-Authors: Jun Meng, Ting Xiang, Zexiong Chen, Shijun Zhang
    Abstract:

    Background: Based on the principle of “Spleen governing transportation and transformation”, we have found that acupuncture of the Five Shu Acupoints in Spleen Meridian can remarkably lower the blood uric acid levels in patients with primary hyperuricemia. Objective: To explore the clinical efficacy of the acupuncture of the Five Shu Acupoints in Spleen Meridian in reducing the blood uric acid level and its relevant mechanism Methods: A total of 32 patients with primary hyperuricemia were enrolled in this study. They were allowed to have free access to diets. The initial treatment for the concomitant diseases (but not including the therapy that might affect uric acid metabolism) was kept unchanged. The observation was formally initiated at 8:00 am on day 1. Acupuncture was not performed within the 48 hours, and only the 24-hour urine volume was recorded. The urine uric acid concentration and urinary creatinine concentration were measured from 25 to 48 hours. On the 46th hour, venous blood samples were collected to detect blood uric acid and creatinine concentrations. After the 48th hour, the patients received acupuncture of the Five Shu Acupoints in Spleen Meridian each morning. Once Qi was encountered, retain the needle for 30 min. The acupuncture was performed once daily for ten consecutive days. The 24-hour urine volume was recorded daily, and the fasting indicators were detected on the morning of the 11th day. Results: After the acupuncture, the blood uric acid level significantly decreased in patients with increased production (overproduction) of uric acid, decreased excretion (underexcretion) of uric acid, and mixed type (all P<0.01). In the underexcretion type, the urine uric acid concentration significantly increased after the treatment (P<0.01). After the acupuncture, the fraction excretion of uric acid (FEUA) significantly increased in the underexcretion type and mixed type (P<0.01) and decreased in the overproduction type (P<0.01). After the acupuncture, the serum uric acid concentration decreased by 16.32-18.29% whereas the 24-hour urine volume increased by 24.22-29.32%. Conclusions: Acupuncture of the Five Shu Acupoints in Spleen Meridian can lower the blood uric acid levels by promoting uric acid excretion the and increasing urine volume.

  • Acupuncture of the Five Shu Acupoints in Spleen Meridian to lower blood uric acid level
    Annals of palliative medicine, 2014
    Co-Authors: Jun Meng, Ting Xiang, Zexiong Chen, Shijun Zhang
    Abstract:

    Background: Based on the principle of “Spleen governing transportation and transformation”, we have found that acupuncture of the Five Shu Acupoints in Spleen Meridian can remarkably lower the blood uric acid levels in patients with primary hyperuricemia. Objective: To explore the clinical efficacy of the acupuncture of the Five Shu Acupoints in Spleen Meridian in reducing the blood uric acid level and its relevant mechanism Methods: A total of 32 patients with primary hyperuricemia were enrolled in this study. They were allowed to have free access to diets. The initial treatment for the concomitant diseases (but not including the therapy that might affect uric acid metabolism) was kept unchanged. The observation was formally initiated at 8:00 am on day 1. Acupuncture was not performed within the 48 hours, and only the 24-hour urine volume was recorded. The urine uric acid concentration and urinary creatinine concentration were measured from 25 to 48 hours. On the 46th hour, venous blood samples were collected to detect blood uric acid and creatinine concentrations. After the 48th hour, the patients received acupuncture of the Five Shu Acupoints in Spleen Meridian each morning. Once Qi was encountered, retain the needle for 30 min. The acupuncture was performed once daily for ten consecutive days. The 24-hour urine volume was recorded daily, and the fasting indicators were detected on the morning of the 11th day. Results: After the acupuncture, the blood uric acid level significantly decreased in patients with increased production (overproduction) of uric acid, decreased excretion (underexcretion) of uric acid, and mixed type (all P

Yi-chun Ma - One of the best experts on this subject based on the ideXlab platform.

  • Safe needling depths of upper back acupoints in children: a retrospective study
    BMC Complementary and Alternative Medicine, 2016
    Co-Authors: Yi-chun Ma, Ching-tien Peng, Yu-chuen Huang
    Abstract:

    Background Acupuncture is applied for treating numerous conditions in children, but few studies have examined the safe needling depth of acupoints in the pediatric population. In this study, we investigated the depths to which acupuncture needles can be inserted safely in the upper back acupoints of children and the variations in safe depth according to sex, age, weight, and body mass index (BMI). Methods We retrospectively studied computed tomography (CT) images of patients aged 4 to 18 years who underwent chest CT at China Medical University Hospital between December 2004 and May 2013. The safe depths of 23 upper back acupoints in the Governor Vessel (GV), Bladder Meridian (BL), Small Intestine Meridian (SI), Gallbladder Meridian (GB) and Spleen Meridian (SP) were measured directly from the CT images. The relationships between the safe depths of these acupoints and sex, age, body weight, and BMI were analyzed. Results The results indicated significant differences in safe needling depth between boys and girls in most upper back acupoints, except at BL42, BL44, BL45, BL46, GB21 and SP21. Safe depths differed significantly depending on age ( p  

  • Safe needling depths of upper back acupoints in children: a retrospective study
    BMC Complementary and Alternative Medicine, 2016
    Co-Authors: Yi-chun Ma, Ching-tien Peng, Yu-chuen Huang
    Abstract:

    Acupuncture is applied for treating numerous conditions in children, but few studies have examined the safe needling depth of acupoints in the pediatric population. In this study, we investigated the depths to which acupuncture needles can be inserted safely in the upper back acupoints of children and the variations in safe depth according to sex, age, weight, and body mass index (BMI). We retrospectively studied computed tomography (CT) images of patients aged 4 to 18 years who underwent chest CT at China Medical University Hospital between December 2004 and May 2013. The safe depths of 23 upper back acupoints in the Governor Vessel (GV), Bladder Meridian (BL), Small Intestine Meridian (SI), Gallbladder Meridian (GB) and Spleen Meridian (SP) were measured directly from the CT images. The relationships between the safe depths of these acupoints and sex, age, body weight, and BMI were analyzed. The results indicated significant differences in safe needling depth between boys and girls in most upper back acupoints, except at BL42, BL44, BL45, BL46, GB21 and SP21. Safe depths differed significantly depending on age (p 

  • The Depths from Skin to the Major Organs at Chest Acupoints of Pediatric Patients
    Evidence-based Complementary and Alternative Medicine, 2015
    Co-Authors: Yi-chun Ma, Ching-tien Peng, Yu-chuen Huang
    Abstract:

    Background. Acupuncture is applied to treat numerous diseases in pediatric patients. Few reports have been published on the depth to which it is safe to insert needle acupoints in pediatric patients. We evaluated the depths to which acupuncture needles can be inserted safely in chest acupoints in pediatric patients and the variations in safe depth according to sex, age, body weight, and body mass index (BMI). Methods. We retrospectively studied computed tomography (CT) images of pediatric patients aged 4 to 18 years who had undergone chest CT at China Medical University Hospital from December 2004 to May 2013. The safe depth of chest acupoints was directly measured from the CT images. The relationships between the safe depth of these acupoints and sex, age, body weight, and BMI were analyzed. Results. The results demonstrated significant differences in depth among boys and girls at KI25 (kidney Meridian), ST16 (stomach Meridian), ST18, SP17 (Spleen Meridian), SP19, SP20, PC1 (pericardium Meridian), LU2 (lung Meridian), and GB22 (gallbladder Meridian). Safe depth significantly differed among the age groups (P < 0.001), weight groups (P < 0.05), and BMI groups (P < 0.05). Conclusion. Physicians should focus on large variations in needle depth during acupuncture for achieving optimal therapeutic effect and preventing complications.

Ting Xiang - One of the best experts on this subject based on the ideXlab platform.

  • Acupuncture for serum uric acid in patients with asymptomatic hyperuricemia: A randomized, double-blind, placebo-controlled trial
    International Journal of Cardiology, 2017
    Co-Authors: Yingjuan Huang, Jun Meng, Ting Xiang, Zexiong Chen, Xin Zhou, Bi‐yu Xu, Yingzi Wu, Shijun Zhang
    Abstract:

    Abstract Background Hyperuricemia (HUA) is the most common disease associated with cardiovascular disease, metabolic syndrome, hypertension, and kidney disease. The objective of the current study was to evaluate the preliminary efficacy, mechanism, and safety of acupuncture on serum uric acid in patients with asymptomatic HUA. Methods A randomized, placebo-controlled trial among 123 patients with asymptomatic HUA was conducted. The acupoints used in the acupuncture group were bilateral Five Shu in Spleen Meridian . Each participant received the intervention once daily for 10 consecutive days. The sham group received the same treatment duration on the same acupoints by the Park Sham Device. All patients underwent measurements of serum or urine creatinine, uric acid, serum lipid profiles, fasting plasma glucose, HbA1c, xanthine oxidase (XOD) and urate-anion exchanger (URAT-1). Results At the end of the intervention, the individuals in the acupuncture group were found to have significantly less levels of serum uric acid than those in the sham group [(453±65 vs. 528±81) μmol/L, p p p Conclusions Acupuncture on Five Shu in Spleen Meridian appeared to be safe and efficacious for decreasing serum uric acid in a Chinese HUA patient population. The mechanism might be associated with the decrease level of enzyme URAT-1. Chinese clinical trial registration ChiCTR-TRC-13004122

  • acupuncture of the five shu acupoints in Spleen Meridian to lower blood uric acid level
    Annals of palliative medicine, 2014
    Co-Authors: Jun Meng, Ting Xiang, Zexiong Chen, Shijun Zhang
    Abstract:

    Background: Based on the principle of “Spleen governing transportation and transformation”, we have found that acupuncture of the Five Shu Acupoints in Spleen Meridian can remarkably lower the blood uric acid levels in patients with primary hyperuricemia. Objective: To explore the clinical efficacy of the acupuncture of the Five Shu Acupoints in Spleen Meridian in reducing the blood uric acid level and its relevant mechanism Methods: A total of 32 patients with primary hyperuricemia were enrolled in this study. They were allowed to have free access to diets. The initial treatment for the concomitant diseases (but not including the therapy that might affect uric acid metabolism) was kept unchanged. The observation was formally initiated at 8:00 am on day 1. Acupuncture was not performed within the 48 hours, and only the 24-hour urine volume was recorded. The urine uric acid concentration and urinary creatinine concentration were measured from 25 to 48 hours. On the 46th hour, venous blood samples were collected to detect blood uric acid and creatinine concentrations. After the 48th hour, the patients received acupuncture of the Five Shu Acupoints in Spleen Meridian each morning. Once Qi was encountered, retain the needle for 30 min. The acupuncture was performed once daily for ten consecutive days. The 24-hour urine volume was recorded daily, and the fasting indicators were detected on the morning of the 11th day. Results: After the acupuncture, the blood uric acid level significantly decreased in patients with increased production (overproduction) of uric acid, decreased excretion (underexcretion) of uric acid, and mixed type (all P<0.01). In the underexcretion type, the urine uric acid concentration significantly increased after the treatment (P<0.01). After the acupuncture, the fraction excretion of uric acid (FEUA) significantly increased in the underexcretion type and mixed type (P<0.01) and decreased in the overproduction type (P<0.01). After the acupuncture, the serum uric acid concentration decreased by 16.32-18.29% whereas the 24-hour urine volume increased by 24.22-29.32%. Conclusions: Acupuncture of the Five Shu Acupoints in Spleen Meridian can lower the blood uric acid levels by promoting uric acid excretion the and increasing urine volume.

  • Acupuncture of the Five Shu Acupoints in Spleen Meridian to lower blood uric acid level
    Annals of palliative medicine, 2014
    Co-Authors: Jun Meng, Ting Xiang, Zexiong Chen, Shijun Zhang
    Abstract:

    Background: Based on the principle of “Spleen governing transportation and transformation”, we have found that acupuncture of the Five Shu Acupoints in Spleen Meridian can remarkably lower the blood uric acid levels in patients with primary hyperuricemia. Objective: To explore the clinical efficacy of the acupuncture of the Five Shu Acupoints in Spleen Meridian in reducing the blood uric acid level and its relevant mechanism Methods: A total of 32 patients with primary hyperuricemia were enrolled in this study. They were allowed to have free access to diets. The initial treatment for the concomitant diseases (but not including the therapy that might affect uric acid metabolism) was kept unchanged. The observation was formally initiated at 8:00 am on day 1. Acupuncture was not performed within the 48 hours, and only the 24-hour urine volume was recorded. The urine uric acid concentration and urinary creatinine concentration were measured from 25 to 48 hours. On the 46th hour, venous blood samples were collected to detect blood uric acid and creatinine concentrations. After the 48th hour, the patients received acupuncture of the Five Shu Acupoints in Spleen Meridian each morning. Once Qi was encountered, retain the needle for 30 min. The acupuncture was performed once daily for ten consecutive days. The 24-hour urine volume was recorded daily, and the fasting indicators were detected on the morning of the 11th day. Results: After the acupuncture, the blood uric acid level significantly decreased in patients with increased production (overproduction) of uric acid, decreased excretion (underexcretion) of uric acid, and mixed type (all P