The Experts below are selected from a list of 243 Experts worldwide ranked by ideXlab platform
I Lindsay - One of the best experts on this subject based on the ideXlab platform.
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a case of pregnancy following a modified Strassman procedure applied to treat a placental site trophoblastic tumour
British Journal of Obstetrics and Gynaecology, 2012Co-Authors: Srdjan Saso, Jayanta Chatterjee, J Yazbek, Y Thum, K W Keefe, Y Abdallah, O Naji, I Lindsay, Philip Savage, Michael J SecklAbstract:Please cite this paper as: Saso S, Chatterjee J, Yazbek J, Thum Y, Keefe K, Abdallah Y, Naji O, Lindsay I, Savage P, Seckl M, Smith J. A case of pregnancy following a modified Strassman procedure applied to treat a placental site trophoblastic tumour. BJOG 2012; DOI: 10.1111/j.1471-0528.2012.03501.x.
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Placental site trophoblastic tumours and the concept of fertility preservation
British Journal of Obstetrics and Gynaecology, 2011Co-Authors: Srdjan Saso, I Lindsay, Michael J Seckl, J Haddad, P Ellis, Neil J. Sebire, A. Mcindoe, SmithAbstract:Please cite this paper as: Saso S, Haddad J, Ellis P, Lindsay I, Sebire N, McIndoe A, Seckl M, Smith J. Placental site trophoblastic tumours and the concept of fertility preservation. BJOG 2011; DOI: 10.1111/j.1471-0528.2011.03230.x. The standard management of placental site trophoblastic tumours (PSTTs) is a radical hysterectomy with pelvic lymph node sampling. We present five cases to demonstrate a modified Strassman procedure (MSP), which is an alternative fertility-sparing technique. Each had a presumed solitary uterine PSTT. Following surgery, one patient remained in remission with her fertility intact. The other four underwent a completion hysterectomy because of incomplete excision of the disease. No residual disease was later found in two of these four uteri. This treatment should only be offered after extensive counselling. We intend to investigate the use of intraoperative frozen section analysis with cold-knife dissection in future.
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Selective vessel ligation in the pelvis: an invaluable tool in certain surgical procedures
International Journal of Gynecological Cancer, 2005Co-Authors: K Sieunarine, I Lindsay, P. Moxey, Deborah C M Boyle, Laszlo Ungar, G. Del Priore, J R SmithAbstract:While developing the technique of abdominal radical trachelectomy for conservative cervical cancer management, the vascular supply of the uterus was thoroughly examined. The question of how many vessels the uterus requires to ensure its viability arose. Following an abdominal radical trachelectomy for stage IB cervical carcinoma, blood supply of the body of the uterus is successfully maintained by only the two infundibulopelvic vessels (n = 34). Pregnancy has resulted following this technique (n = 2). Selective ligation of the pelvic vasculature has been utilized in the abdominal radical trachelectomy procedure. The objectives of this study were to investigate the vasculature of the infundibulopelvic and broad ligaments, to assess the contribution of the ovarian and uterine vessels to overall uterine perfusion, and to consider the clinical applications of selective pelvic vessel ligation. Ten fresh dissections of the infundibulopelvic vessels, broad ligaments of benign total abdominal hysterectomy, and bilateral salpingo-oophorectomy specimens were performed. Perfusion index (PI) and oxygen saturation (O2Sat) measurements using a modified probe were taken at specified intervals at the uterine cornu during ten routine benign abdominal hysterectomies to assess the contribution of the ovarian and uterine vessels to overall uterine perfusion and the concepts studied were utilized in certain gynecological procedures. The ovarian/infundibulopelvic vessels course medially through the broad ligament toward the uterine cornu and consistently give off a branch to the ovary on its lateral border. In addition, further vessels were noted to run laterally from the uterine cornu along the ovarian ligament to the medial aspect of the ovary. PI and O2Sat measurements imply that the uterine and ovarian vessels contribute almost equally to uterine perfusion. Clinical application by selective ligation of the pelvic vasculature has been utilized in certain gynecological procedures often prone to torrential life-threatening uterine hemorrhage. Selective temporary ligation of the uterine and ovarian vessels has proven useful in the surgical management of chemoresistant gestational trophoblastic disease, in the Strassman procedure, fertility-sparing surgery in ruptured cornual ectopic pregnancies, and unrelenting postpartum hemorrhage. Of the six supplying vessels (ovarian, uterine, and vaginal) to the uterus only two (ovarian or uterine or a combination thereof) are required for uterine viability.
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a novel approach in the management of a recurrent adenomatoid tumor of the uterus utilizing a Strassman technique
International Journal of Gynecological Cancer, 2005Co-Authors: K Sieunarine, I Lindsay, A S Cowie, J D Bartlett, J R SmithAbstract:Adenomatoid tumors of the uterus are uncommon benign lesions derived from mesothelium, with a prevalence of 1.2% in one study of 1 000 unselected hysterectomy specimens. They are usually small and near the serosal surface; however, they may be large and diffuse (giant adenomatoid tumors). They coexist with leiomyomas in 60% of cases. A 33-year-old nulliparous woman was referred for severe menorrhagia and dysmenorrhea, thought to be due to a submucosal fibroid on ultrasound. This transpired to be an adenomatoid tumor, and she underwent three transcervical resections of the tumor (TCRT) over a period of 12 months for tumor recurrence and failure of symptom resolution. The last TCRT was performed with ultrasound guidance and laparoscopic visualization of the uterus to the resection point of blanching of the serosal surface. She failed to respond to a GnRH analogue throughout. A specialist opinion on the suitability of vascular embolization of the tumor judged that it would be ineffective for this lesion. She then underwent a Strassman procedure and removal of the adenomatoid tumor. This involved dissection of ureters and pelvic vasculature, selective temporary ligation of uterine arteries, hemisection of the uterus, and excision of the tumor with frozen sections to ensure clear tumor margins and resuturing of the uterine halves. Temporary vascular occlusion of the uterine arteries and ovarian vessels allowed a Strassman procedure, which resulted in successful resection of a recurrent giant adenomatoid tumor of the uterus, with fertility preservation in a young nulliparous woman. Two and a half years on there is no evidence of tumor recurrence.
J R Smith - One of the best experts on this subject based on the ideXlab platform.
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Selective vessel ligation in the pelvis: an invaluable tool in certain surgical procedures
International Journal of Gynecological Cancer, 2005Co-Authors: K Sieunarine, I Lindsay, P. Moxey, Deborah C M Boyle, Laszlo Ungar, G. Del Priore, J R SmithAbstract:While developing the technique of abdominal radical trachelectomy for conservative cervical cancer management, the vascular supply of the uterus was thoroughly examined. The question of how many vessels the uterus requires to ensure its viability arose. Following an abdominal radical trachelectomy for stage IB cervical carcinoma, blood supply of the body of the uterus is successfully maintained by only the two infundibulopelvic vessels (n = 34). Pregnancy has resulted following this technique (n = 2). Selective ligation of the pelvic vasculature has been utilized in the abdominal radical trachelectomy procedure. The objectives of this study were to investigate the vasculature of the infundibulopelvic and broad ligaments, to assess the contribution of the ovarian and uterine vessels to overall uterine perfusion, and to consider the clinical applications of selective pelvic vessel ligation. Ten fresh dissections of the infundibulopelvic vessels, broad ligaments of benign total abdominal hysterectomy, and bilateral salpingo-oophorectomy specimens were performed. Perfusion index (PI) and oxygen saturation (O2Sat) measurements using a modified probe were taken at specified intervals at the uterine cornu during ten routine benign abdominal hysterectomies to assess the contribution of the ovarian and uterine vessels to overall uterine perfusion and the concepts studied were utilized in certain gynecological procedures. The ovarian/infundibulopelvic vessels course medially through the broad ligament toward the uterine cornu and consistently give off a branch to the ovary on its lateral border. In addition, further vessels were noted to run laterally from the uterine cornu along the ovarian ligament to the medial aspect of the ovary. PI and O2Sat measurements imply that the uterine and ovarian vessels contribute almost equally to uterine perfusion. Clinical application by selective ligation of the pelvic vasculature has been utilized in certain gynecological procedures often prone to torrential life-threatening uterine hemorrhage. Selective temporary ligation of the uterine and ovarian vessels has proven useful in the surgical management of chemoresistant gestational trophoblastic disease, in the Strassman procedure, fertility-sparing surgery in ruptured cornual ectopic pregnancies, and unrelenting postpartum hemorrhage. Of the six supplying vessels (ovarian, uterine, and vaginal) to the uterus only two (ovarian or uterine or a combination thereof) are required for uterine viability.
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a novel approach in the management of a recurrent adenomatoid tumor of the uterus utilizing a Strassman technique
International Journal of Gynecological Cancer, 2005Co-Authors: K Sieunarine, I Lindsay, A S Cowie, J D Bartlett, J R SmithAbstract:Adenomatoid tumors of the uterus are uncommon benign lesions derived from mesothelium, with a prevalence of 1.2% in one study of 1 000 unselected hysterectomy specimens. They are usually small and near the serosal surface; however, they may be large and diffuse (giant adenomatoid tumors). They coexist with leiomyomas in 60% of cases. A 33-year-old nulliparous woman was referred for severe menorrhagia and dysmenorrhea, thought to be due to a submucosal fibroid on ultrasound. This transpired to be an adenomatoid tumor, and she underwent three transcervical resections of the tumor (TCRT) over a period of 12 months for tumor recurrence and failure of symptom resolution. The last TCRT was performed with ultrasound guidance and laparoscopic visualization of the uterus to the resection point of blanching of the serosal surface. She failed to respond to a GnRH analogue throughout. A specialist opinion on the suitability of vascular embolization of the tumor judged that it would be ineffective for this lesion. She then underwent a Strassman procedure and removal of the adenomatoid tumor. This involved dissection of ureters and pelvic vasculature, selective temporary ligation of uterine arteries, hemisection of the uterus, and excision of the tumor with frozen sections to ensure clear tumor margins and resuturing of the uterine halves. Temporary vascular occlusion of the uterine arteries and ovarian vessels allowed a Strassman procedure, which resulted in successful resection of a recurrent giant adenomatoid tumor of the uterus, with fertility preservation in a young nulliparous woman. Two and a half years on there is no evidence of tumor recurrence.
Bruno Van Herendael - One of the best experts on this subject based on the ideXlab platform.
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laparoscopic Strassman s metroplasty for bicornuate uterus
Gynecological Surgery, 2009Co-Authors: Sanket Pisat, Bruno Van HerendaelAbstract:The authors report the case of a 28-year-old nulliparous woman with a bicornuate uterus and one previous second trimester pregnancy loss, in whom investigations for other probable causes of abortion like genetic, infective, hormonal, and immunological were negative. A laparoscopic metroplasty was performed by Strassman’s method. Second-look hysteroscopy and laparoscopy, which was performed 7 months later, revealed a single uniform cavity with a median muscular ridge, which resembled an arcuate uterus. Pelvic adhesions were noted between the small bowel, omentum, and posterior wall of the uterus, along with pelvic endometriosis and a chocolate cyst of the left ovary. Adhesiolysis, cyst excision, and fulgration of endometriotic deposits were carried out, which were followed by the application of an adhesion barrier.
Matti Pitkänen - One of the best experts on this subject based on the ideXlab platform.
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Psychedelic induced experiences as key to the understanding of the connection between magnetic body and information molecules
viXra, 2020Co-Authors: Matti PitkänenAbstract:There is a book about psychedelics titled as "Inner paths to outer space: Journies to Alien Worlds through Psychedelics and Other Spiritual Technics" written by Rick Strassman, Slawek Wojtowicz, Luis Eduardo Luna and Ede Frecska. The basic message of the book is that psychedelics might make possible instantaneous remote communications with distant parts of the Universe. The basic objection is that light velocity sets stringent limits on classical communications. In TGD framework this argument does not apply. In the article a model for remote mental interactions is constructed using basic notions of TGD inspired quantum biology such as magnetic body, dark photons, and Zero Energy Ontology.
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Why Information Molecules Containing Aromatic Rings Should Be so Important
2015Co-Authors: Matti PitkänenAbstract:The basic message in the book, "Inner paths to outer space: Journeys to Alien Worlds through Psychedelics and Other Spiritual Technics", written by Rick Strassman et al, is that psychedelics might make possible instantaneous remote communications with distant parts of the Universe. The objection would be that light velocity sets stringent limits on classical communications. In TGD framework this argument does not apply. In this article a model for remote mental interactions is constructed using basic notions of TGD inspired quantum biology such as magnetic body, dark photons and Zero Energy Ontology. Further, both psychedelics and DNA contain aromatic rings. Each base-pair would contain 1+2+1+1=5 (two rings from sugars) aromatic rings and longer DNA sequences would define larger conscious entities. Of course, all proteins contain these aromatic rings possibly integrating by flux tube connections to larger conscious entities. In this picture it would not be surprising of the basic information molecules would also involve aromatic rings.
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Psychedelic Induced Experiences, Magnetic Body & Information Molecules
Journal of Consciousness Exploration & Research, 2015Co-Authors: Matti PitkänenAbstract:The basic message in the book, "Inner paths to outer space: Journeys to Alien Worlds through Psychedelics and Other Spiritual Technics", written by Rick Strassman et al is that psychedelics might make possible instantaneous remote communications with distant parts of the Universe. The objection would be that light velocity sets stringent limits on classical communications. In TGD framework this argument does not apply. In this article a model for remote mental interactions is constructed using basic notions of TGD inspired quantum biology such as magnetic body, dark photons and Zero Energy Ontology.
Michael J Seckl - One of the best experts on this subject based on the ideXlab platform.
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a case of pregnancy following a modified Strassman procedure applied to treat a placental site trophoblastic tumour
British Journal of Obstetrics and Gynaecology, 2012Co-Authors: Srdjan Saso, Jayanta Chatterjee, J Yazbek, Y Thum, K W Keefe, Y Abdallah, O Naji, I Lindsay, Philip Savage, Michael J SecklAbstract:Please cite this paper as: Saso S, Chatterjee J, Yazbek J, Thum Y, Keefe K, Abdallah Y, Naji O, Lindsay I, Savage P, Seckl M, Smith J. A case of pregnancy following a modified Strassman procedure applied to treat a placental site trophoblastic tumour. BJOG 2012; DOI: 10.1111/j.1471-0528.2012.03501.x.
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Placental site trophoblastic tumours and the concept of fertility preservation
British Journal of Obstetrics and Gynaecology, 2011Co-Authors: Srdjan Saso, I Lindsay, Michael J Seckl, J Haddad, P Ellis, Neil J. Sebire, A. Mcindoe, SmithAbstract:Please cite this paper as: Saso S, Haddad J, Ellis P, Lindsay I, Sebire N, McIndoe A, Seckl M, Smith J. Placental site trophoblastic tumours and the concept of fertility preservation. BJOG 2011; DOI: 10.1111/j.1471-0528.2011.03230.x. The standard management of placental site trophoblastic tumours (PSTTs) is a radical hysterectomy with pelvic lymph node sampling. We present five cases to demonstrate a modified Strassman procedure (MSP), which is an alternative fertility-sparing technique. Each had a presumed solitary uterine PSTT. Following surgery, one patient remained in remission with her fertility intact. The other four underwent a completion hysterectomy because of incomplete excision of the disease. No residual disease was later found in two of these four uteri. This treatment should only be offered after extensive counselling. We intend to investigate the use of intraoperative frozen section analysis with cold-knife dissection in future.