The Experts below are selected from a list of 3015 Experts worldwide ranked by ideXlab platform
Takashi Takahashi - One of the best experts on this subject based on the ideXlab platform.
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clinical aspects of invasive infection with Streptococcus Dysgalactiae subsp equisimilis in elderly patients
Journal of Infection and Chemotherapy, 2010Co-Authors: Takashi Takahashi, Naoko Chiba, Ryoko Asami, Kanako Tanabe, Yasuo Hirono, Yukiko Nozawa, Kimiko UbukataAbstract:The number of patients with severe invasive infections (mainly exhibiting bacteremia) with Streptococcus Dysgalactiae subsp. equisimilis (SDSE) has been increasing worldwide. We herein report the clinical aspects of invasive infections (cellulitis, pneumonia, and urosepsis) occurring with SDSE in 13 elderly patients (mean age 84 years, range 69–99 years) diagnosed at a hospital for elderly individuals during the period January 2005–June 2009. Ten subjects had underlying diseases, including neurologic disorders, diabetes mellitus, and others. Eleven patients presented to the hospital emergency department, and the most common symptom was high fever or respiratory distress. Primary care and emergency department doctors treating elderly patients with high fever should keep in mind invasive SDSE infection as a differential diagnosis, especially when an elderly person has underlying illnesses. To detect SDSE in elderly subjects, blood cultures should be obtained before the administration of antimicrobials because, as we found, the patients’ symptoms were limited.
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Neonatal streptococcal toxic shock syndrome caused by Streptococcus Dysgalactiae subsp. equisimilis.
The Pediatric infectious disease journal, 2010Co-Authors: Shigeo Yamaoka, Tohru Ogihara, Masako Yasui, Masashi Hasegawa, Seigo Hira, Shinya Oue, Kimiko Ubukata, Haruo Watanabe, Takashi TakahashiAbstract:We report a neonatal infection with Streptococcus Dysgalactiae subsp. equisimilis occurring through maternal transmission and presenting as streptococcal toxic shock syndrome 12 hours after birth. Pediatricians and obstetricians should be aware of the possibility of this infectious disease when examining newborns with fever. These observations suggest that antenatal maternal screening for S. Dysgalactiae subsp. equisimilis should be considered.
Kimiko Ubukata - One of the best experts on this subject based on the ideXlab platform.
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Molecular Characterization of Invasive Streptococcus Dysgalactiae subsp. equisimilis, Japan
Emerging infectious diseases, 2016Co-Authors: Takeaki Wajima, Miyuki Morozumi, Shigeo Hanada, Katsuhiko Sunaoshi, Naoko Chiba, Satoshi Iwata, Kimiko UbukataAbstract:We collected β-hemolytic streptococci (1,611 isolates) from patients with invasive streptococcal infections in Japan during April 2010-March 2013. Streptococcus Dysgalactiae subsp. equisimilis (SDSE) was most common (n = 693); 99% of patients with SDSE infections were elderly (mean age 75 years, SD ±15 years). We aimed to clarify molecular and epidemiologic characteristics of SDSE isolates and features of patient infections. Bacteremia with no identified focus of origin and cellulitis were the most prevalent manifestations; otherwise, clinical manifestations resembled those of S. pyogenes infections. Clinical manifestations also differed by patient's age. SDSE isolates were classified into 34 emm types; stG6792 was most prevalent (27.1%), followed by stG485 and stG245. Mortality rates did not differ according to emm types. Multilocus sequence typing identified 46 sequence types and 12 novel types. Types possessing macrolide- and quinolone-resistance genes were 18.4% and 2.6%, respectively; none showed β-lactam resistance. Among aging populations, invasive SDSE infections are an increasing risk.
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clinical aspects of invasive infection with Streptococcus Dysgalactiae subsp equisimilis in elderly patients
Journal of Infection and Chemotherapy, 2010Co-Authors: Takashi Takahashi, Naoko Chiba, Ryoko Asami, Kanako Tanabe, Yasuo Hirono, Yukiko Nozawa, Kimiko UbukataAbstract:The number of patients with severe invasive infections (mainly exhibiting bacteremia) with Streptococcus Dysgalactiae subsp. equisimilis (SDSE) has been increasing worldwide. We herein report the clinical aspects of invasive infections (cellulitis, pneumonia, and urosepsis) occurring with SDSE in 13 elderly patients (mean age 84 years, range 69–99 years) diagnosed at a hospital for elderly individuals during the period January 2005–June 2009. Ten subjects had underlying diseases, including neurologic disorders, diabetes mellitus, and others. Eleven patients presented to the hospital emergency department, and the most common symptom was high fever or respiratory distress. Primary care and emergency department doctors treating elderly patients with high fever should keep in mind invasive SDSE infection as a differential diagnosis, especially when an elderly person has underlying illnesses. To detect SDSE in elderly subjects, blood cultures should be obtained before the administration of antimicrobials because, as we found, the patients’ symptoms were limited.
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Neonatal streptococcal toxic shock syndrome caused by Streptococcus Dysgalactiae subsp. equisimilis.
The Pediatric infectious disease journal, 2010Co-Authors: Shigeo Yamaoka, Tohru Ogihara, Masako Yasui, Masashi Hasegawa, Seigo Hira, Shinya Oue, Kimiko Ubukata, Haruo Watanabe, Takashi TakahashiAbstract:We report a neonatal infection with Streptococcus Dysgalactiae subsp. equisimilis occurring through maternal transmission and presenting as streptococcal toxic shock syndrome 12 hours after birth. Pediatricians and obstetricians should be aware of the possibility of this infectious disease when examining newborns with fever. These observations suggest that antenatal maternal screening for S. Dysgalactiae subsp. equisimilis should be considered.
S. Rantala - One of the best experts on this subject based on the ideXlab platform.
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Streptococcus Dysgalactiae subsp. equisimilis bacteremia: an emerging infection
European Journal of Clinical Microbiology & Infectious Diseases, 2014Co-Authors: S. RantalaAbstract:The importance of group C and G Streptococcus Dysgalactiae subspecies equisimilis ( S. Dysgalactiae subsp. equisimilis ) as a significant pathogen has recently been better recognized. S. Dysgalactiae subsp. equisimilis disease can range in severity from milder skin and soft-tissue conditions such as wound infection, erysipelas, and cellulitis, to life-threatening necrotizing fasciitis and streptococcal toxic shock syndrome, thus sharing the clinical picture with S. pyogenes . The most common clinical manifestation of bacteremia is cellulitis. An increase in the incidence of S. Dysgalactiae subsp. equisimilis bacteremia has been recognized. Invasive forms of this infection are most commonly found in elderly patients with underlying comorbidities and skin breakdown. The case fatality in bacteremia has been reported to be 15–18 %. In this review, the epidemiology, clinical characteristics, and emm types of S. Dysgalactiae subsp. equisimilis bacteremia are summarized.
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Streptococcus Dysgalactiae subsp. equisimilis Bacteremia, Finland, 1995-2004.
Emerging infectious diseases, 2010Co-Authors: S. Rantala, Susanna Vähäkuopus, Jaana Vuopio-varkila, Risto Vuento, Jaana SyrjänenAbstract:We conducted a retrospective population-based study of 140 episodes of Streptococcus Dysgalactiae subsp. equisimilis bacteremia occurring in Finland during 1995-2004. Rare emm types were associated with more severe disease and increased mortality rates. Skin and soft tissue infections were more frequent clinical signs among cases caused by common emm types.
Bård Reiakvam Kittang - One of the best experts on this subject based on the ideXlab platform.
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Exploring the arthritogenicity of Streptococcus Dysgalactiae subspecies equisimilis.
BMC microbiology, 2018Co-Authors: Oddvar Oppegaard, Haima Mylvaganam, Steinar Skrede, Bård Reiakvam KittangAbstract:Background During the past decades, Streptococcus Dysgalactiae subspecies equisimilis (SDSE) has been increasingly recognized as an important human pathogen. Osteoarticular infections is one of the predominant disease manifestations of SDSE, but the pathogenetic rationale for its arthritogenicity has yet to be unravelled. We aimed to explore if the rising incidence of osteoarticular infections caused by this pathogen in our region emanated from clonal expansion of strains with enhanced tropism for bone and joint tissue components or orthopaedic implants.
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New Tricks from an Old Cow: Infective Endocarditis Caused by Streptococcus Dysgalactiae subsp. Dysgalactiae
Journal of clinical microbiology, 2014Co-Authors: Stina Jordal, Oddvar Oppegaard, Marte Glambek, Bård Reiakvam KittangAbstract:We present a case of infective endocarditis caused by Streptococcus Dysgalactiae subsp. Dysgalactiae, a major cause of bovine mastitis and previously thought to be an animal-restricted pathogen. The patient reported no direct contact with animals, and the clinical course was severe and complicated.
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Two Unusual Cases of Severe Soft Tissue Infection Caused by Streptococcus Dysgalactiae subsp. equisimilis
Journal of clinical microbiology, 2010Co-Authors: Bård Reiakvam Kittang, Steinar Skrede, Nina Langeland, Haima MylvaganamAbstract:We present two cases of invasive infection caused by Streptococcus Dysgalactiae subsp. equisimilis, one that showed rapidly developing necrotizing fasciitis in a previously healthy man and one that showed severe cellulitis and septic shock even though the bacterium possessed a mutated emm gene, predicted to encode a truncated M protein.
Shigeo Yamaoka - One of the best experts on this subject based on the ideXlab platform.
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Neonatal streptococcal toxic shock syndrome caused by Streptococcus Dysgalactiae subsp. equisimilis.
The Pediatric infectious disease journal, 2010Co-Authors: Shigeo Yamaoka, Tohru Ogihara, Masako Yasui, Masashi Hasegawa, Seigo Hira, Shinya Oue, Kimiko Ubukata, Haruo Watanabe, Takashi TakahashiAbstract:We report a neonatal infection with Streptococcus Dysgalactiae subsp. equisimilis occurring through maternal transmission and presenting as streptococcal toxic shock syndrome 12 hours after birth. Pediatricians and obstetricians should be aware of the possibility of this infectious disease when examining newborns with fever. These observations suggest that antenatal maternal screening for S. Dysgalactiae subsp. equisimilis should be considered.