The Experts below are selected from a list of 24 Experts worldwide ranked by ideXlab platform
O Celen - One of the best experts on this subject based on the ideXlab platform.
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Lymphatic mapping and sentinel Lymph node biopsy in squamous cell carcinoma of the lower lip
Ejso, 2002Co-Authors: Huseyin Altinyollar, U Berberoglu, O CelenAbstract:Abstract Aims: The risk of metastases to the submandibular and Submental Lymph Nodes in squamous cell carcinoma (SCC) of the lower lip is closely related to the primary tumour size and the differentiation of the tumour. In order to determine the feasibility of the technique and the possible metastatic Lymph Nodes in SCC of the lower lip, intraoperative Lymphatic mapping and sentinel Lymph node biopsy was performed in patients with tumour size greater than 2 cm (T2) and clinically non-palpable regional Lymph Nodes (N0). Methods: Intraoperative Lymphatic mapping with patent blue dye was performed in 20 patients with SCC of the lower lip. The stained Lymph node (sentinel) was identified in each patient and sent for frozen section analysis in order to verify tumour metastasis. All patients had undergone bilateral suprahyoid neck dissection at the same stage. Results: Three of the patients were female and 17 were male. The median age was 66. Sentinel Lymph Nodes were identified in 18 of the patients (90%). Intraoperative or post-operative histopathologic examination of the sentinel Lymph node showed tumour metastasis in three of the patients (16.6%). The histopathologic examination of the remaining 15 patients whose sentinel Lymph Nodes were free of metastasis, showed no metastasis in the non-sentinel Lymph Nodes. In two of the three patients with metastatic sentinel Lymph Nodes, non-sentinel Lymph Nodes were free of metastases. There were no false negative results and no local or systemic complications of the technique were seen among the patients. Conclusions: Intraoperative Lymphatic mapping and sentinel Lymph node biopsy is feasible in patients with SCC of the lower lip who have large tumour size and non-palpable regional Lymph Nodes. The technique may help to avoid neck dissection when the patient has negative sentinel Lymph node and when positive provides useful information for more effective radical treatment.
Shuichi Fujita - One of the best experts on this subject based on the ideXlab platform.
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a case of multiple calcifications in the bilateral submandibular and Submental Lymph Nodes
Japanese Journal of Oral and Maxillofacial Surgery, 2000Co-Authors: Kazutaka Suyama, Souichi Yanamoto, Goro Kawasaki, Michiichirou Itoh, Akio Mizuno, Shuichi FujitaAbstract:We report on a patient with calcification of the bilateral submandibular and Submental Lymph Nodes. A 40-year-old woman had swelling of the buccal gingiva around 5.Panoramic radiography at presentation showed radiopaque images, one in the right submandibular region and one in the left submandibular region. CT examination showed multiple high density masses that appeared calcified, one in the right submandibular region, two in the left submandibular region, and one in the Submental region. We excised the masses from both submandibular and Submental regions under general anesthesia, and found that the masses were covered with a thin fibrous tissue coat ; calcified bodies of various sizes had formed in the Lymph Nodes. Although foreign body giant cells were observed around the calcified bodies, there were no epithelioid cells and no Langerhans' giant cells, which are typically observed in tuberculosis. Ziehl-Neelsen stain was negative. We histopathologically diagnosed the masses as fibrosis with calcification. The clinical course has been good to date, with no recurrence 1 year 5 months postoperatively.
Huseyin Altinyollar - One of the best experts on this subject based on the ideXlab platform.
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Lymphatic mapping and sentinel Lymph node biopsy in squamous cell carcinoma of the lower lip
Ejso, 2002Co-Authors: Huseyin Altinyollar, U Berberoglu, O CelenAbstract:Abstract Aims: The risk of metastases to the submandibular and Submental Lymph Nodes in squamous cell carcinoma (SCC) of the lower lip is closely related to the primary tumour size and the differentiation of the tumour. In order to determine the feasibility of the technique and the possible metastatic Lymph Nodes in SCC of the lower lip, intraoperative Lymphatic mapping and sentinel Lymph node biopsy was performed in patients with tumour size greater than 2 cm (T2) and clinically non-palpable regional Lymph Nodes (N0). Methods: Intraoperative Lymphatic mapping with patent blue dye was performed in 20 patients with SCC of the lower lip. The stained Lymph node (sentinel) was identified in each patient and sent for frozen section analysis in order to verify tumour metastasis. All patients had undergone bilateral suprahyoid neck dissection at the same stage. Results: Three of the patients were female and 17 were male. The median age was 66. Sentinel Lymph Nodes were identified in 18 of the patients (90%). Intraoperative or post-operative histopathologic examination of the sentinel Lymph node showed tumour metastasis in three of the patients (16.6%). The histopathologic examination of the remaining 15 patients whose sentinel Lymph Nodes were free of metastasis, showed no metastasis in the non-sentinel Lymph Nodes. In two of the three patients with metastatic sentinel Lymph Nodes, non-sentinel Lymph Nodes were free of metastases. There were no false negative results and no local or systemic complications of the technique were seen among the patients. Conclusions: Intraoperative Lymphatic mapping and sentinel Lymph node biopsy is feasible in patients with SCC of the lower lip who have large tumour size and non-palpable regional Lymph Nodes. The technique may help to avoid neck dissection when the patient has negative sentinel Lymph node and when positive provides useful information for more effective radical treatment.
Kazutaka Suyama - One of the best experts on this subject based on the ideXlab platform.
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a case of multiple calcifications in the bilateral submandibular and Submental Lymph Nodes
Japanese Journal of Oral and Maxillofacial Surgery, 2000Co-Authors: Kazutaka Suyama, Souichi Yanamoto, Goro Kawasaki, Michiichirou Itoh, Akio Mizuno, Shuichi FujitaAbstract:We report on a patient with calcification of the bilateral submandibular and Submental Lymph Nodes. A 40-year-old woman had swelling of the buccal gingiva around 5.Panoramic radiography at presentation showed radiopaque images, one in the right submandibular region and one in the left submandibular region. CT examination showed multiple high density masses that appeared calcified, one in the right submandibular region, two in the left submandibular region, and one in the Submental region. We excised the masses from both submandibular and Submental regions under general anesthesia, and found that the masses were covered with a thin fibrous tissue coat ; calcified bodies of various sizes had formed in the Lymph Nodes. Although foreign body giant cells were observed around the calcified bodies, there were no epithelioid cells and no Langerhans' giant cells, which are typically observed in tuberculosis. Ziehl-Neelsen stain was negative. We histopathologically diagnosed the masses as fibrosis with calcification. The clinical course has been good to date, with no recurrence 1 year 5 months postoperatively.
Ming-huei Cheng, Md Mba - One of the best experts on this subject based on the ideXlab platform.
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Accurate Prediction of Submental Lymph Nodes Using Magnetic Resonance Imaging for Lymphedema Surgery
Wolters Kluwer, 2018Co-Authors: Mora-ortiz Asuncion, Sung-yu Chu, Yen-ling Huang, Chia-yu Lin Msc, Ming-huei Cheng, Md MbaAbstract:Background:. Submental Lymph node transfer has proved to be an effective approach for the treatment of Lymphedema. This study was to investigate the anatomy and distribution of vascularized Submental Lymph node (VSLN) flap using magnetic resonance imaging (MRI) and their clinical outcome. Methods:. Fifteen patients who underwent 19 VSLN flap transfers for upper or lower limb Lymphedema were retrospectively analyzed. The number of Submental Lymph Nodes was compared among preoperative MRI, preoperative sonography, intraoperative finding, postoperative sonography, and postoperative computed tomography angiography. The outcome was compared between preoperatively and postoperatively. Results:. All 19 VSLN flaps survived. Two hundred fifteen Lymph Nodes were identified in 30 submandibular regions by MRI. The mean number of Submental Lymph Nodes on preoperative MRI was 7.2 ± 2.4, on preoperative sonography was 3.2 ± 1.1, on intraoperative finding was 3.1 ± 0.6, postoperative sonography was 4.6 ± 1.8, and postoperative CTA was 5.2 ± 1.9. Sixty-one percent of the Lymph Nodes were located in the central two-quarters of the line drawn from the mental protuberance to the mandibular angle. The actual harvest rate of Submental Lymph Nodes was 72.2%. At a 12-month follow-up, mean episodes of cellulitis were improved from 2.7 ± 0.6 to 0.8 ± 0.2 (P < 0.01); mean of circumferential difference was improved 3.2 ± 0.4 cm (P < 0.03). The overall Lymphedema quality-of-life was improved 4.9 ± 0.3 (P < 0.04). Conclusions:. The preoperative MRI is a useful tool for the detection of mean 7.2 Submental Lymph Nodes. Mean 72.2% of Submental Lymph Nodes can be successfully transferred for extremity Lymphedema with optimal functional recovery
