The Experts below are selected from a list of 1986 Experts worldwide ranked by ideXlab platform
Guibin Jiang - One of the best experts on this subject based on the ideXlab platform.
-
TetrAbromobisphenol A induces thr β mediAted inflAmmAtion And uterine injury in mice At environmentAlly relevAnt exposure concentrAtions
Journal of Hazardous Materials, 2021Co-Authors: Wenjuan Zhang, Maoyong Song, Yu Pan, Fengbang Wang, Yong Liang, Xinglei Yao, Jinghai Song, Guibin JiangAbstract:AbstrAct TetrAbromobisphenol A (TBBPA) is A widely used flAme retArdAnt, but the Adverse outcomes induced by TBBPA hAs not been fully elucidAted. In this study, TBBPA wAs detected in 54.9% of 102 femAle Chinese volunteers with An AverAge serum concentrAtion of 0.34 ng/mL. To investigAte whether TBBPA induces Adverse outcomes At environmentAlly relevAnt exposure doses, the mice were exposed to TBBPA for 14 And 28 dAys. The internAl doses of TBBPA in mice serum were neArly the internAl doses in volunteers. TBBPA significAntly increAsed the secretion of some pro-inflAmmAtory cytokines And suppressed immune responses in mice under such serum concentrAtions After 14- And 28-dAys exposure. Interestingly, uterine edemA wAs observed in TBBPA-treAted mice. In primAry uterine cells model, the results showed TBBPA exposure suppressed THRβ expression, leAding to the ActivAtion of the inflAmmAtory PI3K/NF-κB signAling pAthwAy. Our findings indicAted thAt the uterus is the susceptible tArget orgAn of TBBPA And TBBPA exposure might increAse risk of uterine cAncer through deregulAting inflAmmAtion pAthwAys.
-
two typicAl glycosylAted metAbolites of TetrAbromobisphenol A formed in plAnts excretion And deglycosylAtion in plAnt root zones
Environmental Science and Technology Letters, 2021Co-Authors: Xingwang Hou, Wenqian Kong, Jiyan Liu, Jerald L Schnoor, Linfeng Wei, Yinyin Tang, Guibin JiangAbstract:The glycosylAtion process wAs investigAted for the common brominAted flAme retArdAnt TetrAbromobisphenol A (TBBPA) in hydroponic exposure systems with pumpkin seedlings. Two typicAl glycosylAtion m...
-
binding And Activity of TetrAbromobisphenol A mono ether structurAl AnAlogs to thyroid hormone trAnsport proteins And receptors
Environmental Health Perspectives, 2020Co-Authors: Xiaomin Ren, Linlin Yao, Qiao Xue, Jianbo Shi, Qinghua Zhang, Pu Wang, Aiqian Zhang, Guibin JiangAbstract:BAckground: TetrAbromobisphenol A (TBBPA) mono-ether structurAl AnAlogs, identified As the by-products or trAnsformAtion products of commerciAl TBBPA bis-ether derivAtives, hAve been identified As ...
-
spAtiAl distribution of pArAbens triclocArbAn triclosAn bisphenols And TetrAbromobisphenol A And its AlternAtives in municipAl sewAge sludges in chinA
Science of The Total Environment, 2019Co-Authors: Yun Wang, Chunyang Liao, Kegang Zhang, He Zhang, Guibin JiangAbstract:AbstrAct PArAbens, triclocArbAn (TCC), triclosAn (TCS), bisphenols (BPs), And TetrAbromobisphenol A And its AlternAtives (TBBPAs) Are used in A broAd rAnge of dAily consumer products And industriAl productions. Concerns hAve been rAised over exposure of humAns to these chemicAls, becAuse of their Adverse heAlth effects. However, informAtion on the spAtiAl distribution of pArAbens, TCC, TCS, BPs And TBBPAs in sludge from wAste wAter treAtment plAnts (WWTPs) in ChinA is still limited. In this study, 19 endocrine disrupting chemicAls, including six pArAbens, two AntimicrobiAls (TCC And TCS), eight BPs And three TBBPAs, were determined in sludges from 46 WWTPs Across ChinA. ConcentrAtions of tArget chemicAls were found in A decreAsed order As: ∑(TCC + TCS) (meAn: 3930, rAnge: 1340–11,100 ng/g dw) > ∑8BPs (201, 23.1–1240 ng/g dw) > ∑6pArAbens (67.9, 10.4–272 ng/g dw) > ∑3TBBPAs (18.4, 1.36–195 ng/g dw). Methyl pArAben (MeP), TCC, bisphenol A (BPA) And TetrAbromobisphenol A (TBBPA) were the mAjor compounds found in sludge, Accounting for 89.0%, 57.7%, 85.8% And 93.3% of ∑6pArAbens, ∑(TCC + TCS), ∑8BPs And ∑3TBBPAs, respectively. ElevAted concentrAtions of BPs And TBBPAs were found in sludges from the NortheAst ChinA And CentrAl South ChinA (p 0.05). CAlculAtion of mAss loAding showed thAt sludge from EAst ChinA (1340 kg/yr) And South CentrAl ChinA (1060 kg/yr) releAsed relAtively more such chemicAls. This nAtionwide study provided bAseline concentrAtions of these chemicAls in sludges And estimAted their environmentAl releAse through sludge in ChinA.
-
Abiotic methylAtion of TetrAbromobisphenol A tbbpA with the occurrence of methyl iodide in Aqueous environments
Environmental Science and Technology Letters, 2019Co-Authors: Xingwang Hou, Wenqian Kong, Xiaoyun Wang, Yanwei Liu, Weifang Chen, Jiyan Liu, Jerald L Schnoor, Guibin JiangAbstract:TetrAbromobisphenol A (TBBPA) is the most widely used brominAted flAme retArdAnt in the world. Its biotic methylAtion products, TetrAbromobisphenol A mono- And dimethyl ether (TBBPA MME And TBBPA DME, respectively), Are frequently detected in the environment, but the importAnce of Abiotic methylAtion reActions of TBBPA in the environment is not known. In this study, the methylAtion of TBBPA mediAted by methyl iodide (CH3I), A ubiquitous compound in Aqueous environments, wAs investigAted in simulAted wAters in the lAborAtory. It wAs found thAt Abiotic methylAtion occurred under both light And dArk conditions And wAs strongly Affected by the pH, temperAture, And nAturAl orgAnic mAtter concentrAtion of the wAter. Abiotic methylAtion wAs further verified in nAturAl river wAter, And the yield of TBBPA MME mediAted AbioticAlly by CH3I wAs much greAter thAn thAt of biotic methylAtion. According to our cAlculAtions And by compArison of the ActivAtion energies (EA) for the Abiotic methylAtion of TBBPA And the other four typicAl phenolic contAminAnts And/or metAbolites (bisphenol A, triclosAn, 5-OH-BDE-47, And 4'-OH-CB-61) mediAted by CH3I, those phenolic compounds All show greAt methylAtion potentiAls. The results indicAte A new Abiotic pAthwAy for generAting TBBPA MME And TBBPA DME from TBBPA, And they Also confirm the potentiAls for Abiotic methylAtion of other phenolic contAminAnts in Aqueous environments.
Yong Tian - One of the best experts on this subject based on the ideXlab platform.
-
screening of brominAted pyrolysis products of TetrAbromobisphenol A by integrAting controllAble heAting device with Ambient mAss spectrometry
Journal of Analytical and Applied Pyrolysis, 2020Co-Authors: Zongshan Zhao, Yong Tian, Yaqi Cai, Aifeng Liu, Huan Liu, Wei Gao, Xiangfeng Chen, Zhenhua WangAbstract:AbstrAct Pyrolysis, An effective recycle strAtegy for resins or plAstic contAining TetrAbromobisphenol A (TBBPA), often leAd to formAtion of more toxic decomposition chemicAls. Online collection coupled with off-line AnAlysis for quAlitAtive And quAntitAtive AnAlysis of the residue often induce informAtion loss of these pyrolysis products. In this study, A temperAture controllAble thermAl decomposition device coupled with An Ambient mAss spectrometry wAs directly employed for on-line monitoring of the pyrolysis process of TBBPA. ThermAl products through debrominAtion, methylAtion, methoxylAtion And β-scission hAve All been detected. BAsed on the mAss spectrA of TBBPA decomposition products, the number of bromine Atoms And the m/z vAlues, About 8 brominAted decomposition products/intermediAtes hAve been identified. TemperAture plAyed the criticAl role for the pyrolysis processes. It wAs found thAt Almost no TBBPA degrAded At low temperAture (100−150 °C), intensified decomposition hAppened At About 300 °C And smAll molecules formed in lArge quAntities At > 450 °C.
-
ultrAsensitive determinAtion of TetrAbromobisphenol A by covAlent orgAnic frAmework bAsed solid phAse microextrAction coupled with constAnt flow desorption ionizAtion mAss spectrometry
Analytical Chemistry, 2019Co-Authors: Yong Tian, Yongliang Yu, Zongshan Zhao, Guibin JiangAbstract:RApid detection of ultrAtrAce pollutAnts in complex mAtrixes is A greAt chAllenge for studying their environmentAl behAviors And impActs. In this work, A method is developed by combining covAlent orgAnic frAmework (COF) bAsed solid phAse microextrAction (SPME) with constAnt flow desorption ionizAtion mAss spectrometry for rApid detection of trAce TetrAbromobisphenol A (TBBPA) in multiple wAter mediA. The limits of detection And quAlificAtion Are 0.92 And 3.1 ng L–1 for TBBPA, respectively. The lineAr rAnge is between 0.01 And 10 μg L–1 (R2 = 0.9992), And the relAtive stAndArd deviAtions with single fiber And multiple fibers Are 6.4% And 6.7% (0.1 μg L–1, n = 9), respectively. The detection of nAnogrAm per liter levels of TBBPA in tAp wAter, river wAter, seAwAter, And beverAge cAn be Achieved in 7 min.
-
UltrAsensitive DeterminAtion of TetrAbromobisphenol A by CovAlent OrgAnic FrAmework BAsed Solid PhAse MicroextrAction Coupled with ConstAnt Flow Desorption IonizAtion MAss Spectrometry
2018Co-Authors: Wei Gao, Yong Tian, Zongshan Zhao, Yaqi Cai, Aifeng Liu, Huan Liu, Guibin JiangAbstract:RApid detection of ultrAtrAce pollutAnts in complex mAtrixes is A greAt chAllenge for studying their environmentAl behAviors And impActs. In this work, A method is developed by combining covAlent orgAnic frAmework (COF) bAsed solid phAse microextrAction (SPME) with constAnt flow desorption ionizAtion mAss spectrometry for rApid detection of trAce TetrAbromobisphenol A (TBBPA) in multiple wAter mediA. The limits of detection And quAlificAtion Are 0.92 And 3.1 ng L–1 for TBBPA, respectively. The lineAr rAnge is between 0.01 And 10 μg L–1 (R2 = 0.9992), And the relAtive stAndArd deviAtions with single fiber And multiple fibers Are 6.4% And 6.7% (0.1 μg L–1, n = 9), respectively. The detection of nAnogrAm per liter levels of TBBPA in tAp wAter, river wAter, seAwAter, And beverAge cAn be Achieved in 7 min
-
silver ion post column derivAtizAtion electrosprAy ionizAtion mAss spectrometry for determinAtion of TetrAbromobisphenol A derivAtives in wAter sAmples
RSC Advances, 2015Co-Authors: Yong Tian, Huanwen Chen, Jian Chen, Jianbo Shi, Aifeng Liu, Chunxiao Liu, Eric Handberg, Guibin JiangAbstract:A rApid And sensitive method wAs developed for the identificAtion And quAntitAtion of TetrAbromobisphenol A (TBBPA) derivAtives in wAter sAmples. Six mAjor TBBPA derivAtives, including TetrAbromobisphenol A bis(2-hydroxyethyl) ether (TBBPA-BHEE), TetrAbromobisphenol A bis(glycidyl) ether (TBBPA-BGE), TetrAbromobisphenol A bis(Allyl) ether (TBBPA-BAE), TetrAbromobisphenol A mono(2-hydroxyethyl) ether (TBBPA-MHEE), TetrAbromobisphenol A mono(glycidyl) ether (TBBPA-MGE) And TetrAbromobisphenol A mono(Allyl) ether (TBBPA-MAE), were selected As the tArget compounds. By Applying the silver cAtion (Ag+) As the post-column derivAtizAtion reAgent, the TBBPA derivAtives formed complexes ([M + Ag]NO3) online, which could be effectively electrosprAyed to generAte ionic clusters ([M + Ag]+) for sensitive mAss AnAlysis. Under the optimized conditions, the 6 TBBPA derivAtives were sepArAted And detected within 10 min. The limits of detection (LODs) were between 0.16 And 1.96 μg L−1, And the lineAr rAnges extended to 200 μg L−1 (R2 ≥ 0.9957). The relAtive stAndArd deviAtions (RSDs) were less thAn 7.7% for 10 μg L−1 of the TBBPA derivAtives (n = 7). The proposed method wAs successfully Applied in AnAlysis of environmentAl wAter sAmples. The spiked recoveries rAnged from 81.3% to 114.9%, suggesting the AccurAcy And feAsibility of the method.
-
reActive extrActive electrosprAy ionizAtion tAndem mAss spectrometry for sensitive detection of TetrAbromobisphenol A derivAtives
Analytica Chimica Acta, 2014Co-Authors: Yong Tian, Yongzhong Ouyang, Guangbo Qu, Huanwen Chen, Xuemei Wang, Jian Chen, Guibin JiangAbstract:Sensitive detection of TetrAbromobisphenol A (TBBPA) And its derivAtives, A group of emerging toxic contAminAnts, is highly necessitAted in environmentAl investigAtion. Herein A novel AnAlyticAl strAtegy bAsed on reActive extrActive electrosprAy ionizAtion (EESI) tAndem mAss spectrometry for detection of TetrAbromobisphenol A bis(2-hydroxyethyl ether) (TBBPA-BHEE), TetrAbromobisphenol A bis(glycidyl ether) (TBBPA-BGE), TetrAbromobisphenol A bis(Allylether) (TBBPA-BAE), And TetrAbromobisphenol S bis(Allylether) (TBBPS-BAE) in industriAl wAste wAter sAmples wAs developed. Active silver cAtions (Ag+), generAted by electrosprAying A silver nitrAte methAnol solution (10 mg L-1), collides the neutrAl TBBPA derivAtives molecules in the EESI source to form [M + Ag](+) complexes of the AnAlytes under the Ambient conditions. Upon collision-induced dissociAtion (CID), chArActeristic frAgments of the [M + Ag](+) complexes were identified for confident And sensitive detection of the four TBBPA derivAtives. Under the optimized experimentAl conditions, the instrumentAl limits of detection (LODs) of TBBPA-BHEE, TBBPA-BGE, TBBPA-BAE And TBBPS-BAE were 0.37, 0.050, 0.76, And 4.6 mu g L-1, respectively. The lineAr rAnges extended to 1000 mu g L-1(R-2 >= 0.9919), And the relAtive stAndArd deviAtions (RSDs), inter-dAy vAriAtion And intrA-dAy vAriAtion were less thAn 7.8% (n = 9), 10.0% (n = 5), And 14.8% (n = 1 per dAy for 5 dAys) for All derivAtives. TBBPA derivAtive mAnufActuring industriAl wAste wAter, river wAter And tAp wAter sAmples were fAst AnAlyzed with the proposed method. The contents of TBBPA derivAtives were vArious in the collected sAmples, with the highest 19.9 x 0.3 mu g L-1 of TBBPA-BAE in the wAste wAter sAmples. (C) 2014 Elsevier B.V. All rights reserved.
Zongshan Zhao - One of the best experts on this subject based on the ideXlab platform.
-
screening of brominAted pyrolysis products of TetrAbromobisphenol A by integrAting controllAble heAting device with Ambient mAss spectrometry
Journal of Analytical and Applied Pyrolysis, 2020Co-Authors: Zongshan Zhao, Yong Tian, Yaqi Cai, Aifeng Liu, Huan Liu, Wei Gao, Xiangfeng Chen, Zhenhua WangAbstract:AbstrAct Pyrolysis, An effective recycle strAtegy for resins or plAstic contAining TetrAbromobisphenol A (TBBPA), often leAd to formAtion of more toxic decomposition chemicAls. Online collection coupled with off-line AnAlysis for quAlitAtive And quAntitAtive AnAlysis of the residue often induce informAtion loss of these pyrolysis products. In this study, A temperAture controllAble thermAl decomposition device coupled with An Ambient mAss spectrometry wAs directly employed for on-line monitoring of the pyrolysis process of TBBPA. ThermAl products through debrominAtion, methylAtion, methoxylAtion And β-scission hAve All been detected. BAsed on the mAss spectrA of TBBPA decomposition products, the number of bromine Atoms And the m/z vAlues, About 8 brominAted decomposition products/intermediAtes hAve been identified. TemperAture plAyed the criticAl role for the pyrolysis processes. It wAs found thAt Almost no TBBPA degrAded At low temperAture (100−150 °C), intensified decomposition hAppened At About 300 °C And smAll molecules formed in lArge quAntities At > 450 °C.
-
identificAtion of trAnsformAtion degrAdAtion products of TetrAbromobisphenol A And its derivAtives
Trends in Analytical Chemistry, 2019Co-Authors: Aifeng Liu, Jianbo Shi, Zongshan Zhao, Zhaoshuang Shen, Xiangfeng Liang, Guibing JiangAbstract:AbstrAct The structurAl identificAtion As well As quAntitAtive AnAlysis of trAnsformAtion And degrAdAtion (T/D) products of TetrAbromobisphenol A (TBBPA) And its derivAtives cAn provide useful informAtion on the corresponding T/D mechAnism As well As environmentAl impAct. However, it is still A greAt chAllenge to AnAlyze trAce levels of T/D products, both unknown And known products, As A result of the complexity of environmentAl mAtrices And the lAck of commerciAl/ArtificiAl stAndArd chemicAls. This criticAl review summArized the T/D model experiments, sAmple prepArAtion And the AssociAted AnAlyticAl methods, including extrAction, purificAtion, concentrAtion, derivAtizAtion, quAntitAtion AnAlysis And 14C-lAbeling technologies. Furthermore, the mAss spectrAl AnAlysis of TBBPA relAted compounds using different AnAlyticAl instruments And T/D products predicted by computer progrAms Are Also described.
-
ultrAsensitive determinAtion of TetrAbromobisphenol A by covAlent orgAnic frAmework bAsed solid phAse microextrAction coupled with constAnt flow desorption ionizAtion mAss spectrometry
Analytical Chemistry, 2019Co-Authors: Yong Tian, Yongliang Yu, Zongshan Zhao, Guibin JiangAbstract:RApid detection of ultrAtrAce pollutAnts in complex mAtrixes is A greAt chAllenge for studying their environmentAl behAviors And impActs. In this work, A method is developed by combining covAlent orgAnic frAmework (COF) bAsed solid phAse microextrAction (SPME) with constAnt flow desorption ionizAtion mAss spectrometry for rApid detection of trAce TetrAbromobisphenol A (TBBPA) in multiple wAter mediA. The limits of detection And quAlificAtion Are 0.92 And 3.1 ng L–1 for TBBPA, respectively. The lineAr rAnge is between 0.01 And 10 μg L–1 (R2 = 0.9992), And the relAtive stAndArd deviAtions with single fiber And multiple fibers Are 6.4% And 6.7% (0.1 μg L–1, n = 9), respectively. The detection of nAnogrAm per liter levels of TBBPA in tAp wAter, river wAter, seAwAter, And beverAge cAn be Achieved in 7 min.
-
A novel And sensitive chemiluminescence immunoAssAy bAsed on Auncs pepsin luminol for simultAneous detection of TetrAbromobisphenol A bis 2 hydroxyethyl ether And TetrAbromobisphenol A mono hydroxyethyl ether
Analytica Chimica Acta, 2018Co-Authors: Zhen Zhang, Zongshan Zhao, Nuanfei Zhu, Yanmin Zou, Guoxi Liang, Zhixiang Han, Hui MengAbstract:AbstrAct A novel chemiluminescence immunoAssAy bAsed on luminol-modified gold nAnoclusters (AuNCs@Peps@luminol) wAs developed for simultAneous detection of TetrAbromobisphenol A bis(2-hydroxyethyl) ether (TBBPA-DHEE) And TetrAbromobisphenol A mono(hydroxyethyl) ether (TBBPA-MHEE), An importAnt derivAtive And byproduct of TetrAbromobisphenol A (TBBPA), respectively. In the system, AlkAline phosphAtAse (ALP) wAs lAbeled on the second Antibody (Ab2) for signAl AmplificAtion. When ALP-Ab2 wAs cAptured by Antigen-primAry Antibody (Ab1) complex, disodium phenyl phosphAte (PPNA) generAted mAssive phenol under the cAtAlysis of ALP, mArkedly inhibiting the chemiluminescence intensity of AuNCs@Peps@luminol. Under the optimized conditions, the cAlculAted detection of limit (LOD, 90% inhibition) wAs 0.078 μg/L for TBBPA-DHEE with A lineAr rAnge of 0.23–9.32 μg/L, which wAs lower 9 times thAn thAt of conventionAl ELISA with the sAme Antibody. In Addition, our method showed sAtisfActory AccurAcy And precision (recoveries, 88.00–113.4%; CV, 2.75–8.14%), it cAn be Applied to systemAticAlly investigAte the concentrAtion of the trAce TBBPA-DHEE And TBBPA-MHEE in environmentAl And food sAmples.
-
UltrAsensitive DeterminAtion of TetrAbromobisphenol A by CovAlent OrgAnic FrAmework BAsed Solid PhAse MicroextrAction Coupled with ConstAnt Flow Desorption IonizAtion MAss Spectrometry
2018Co-Authors: Wei Gao, Yong Tian, Zongshan Zhao, Yaqi Cai, Aifeng Liu, Huan Liu, Guibin JiangAbstract:RApid detection of ultrAtrAce pollutAnts in complex mAtrixes is A greAt chAllenge for studying their environmentAl behAviors And impActs. In this work, A method is developed by combining covAlent orgAnic frAmework (COF) bAsed solid phAse microextrAction (SPME) with constAnt flow desorption ionizAtion mAss spectrometry for rApid detection of trAce TetrAbromobisphenol A (TBBPA) in multiple wAter mediA. The limits of detection And quAlificAtion Are 0.92 And 3.1 ng L–1 for TBBPA, respectively. The lineAr rAnge is between 0.01 And 10 μg L–1 (R2 = 0.9992), And the relAtive stAndArd deviAtions with single fiber And multiple fibers Are 6.4% And 6.7% (0.1 μg L–1, n = 9), respectively. The detection of nAnogrAm per liter levels of TBBPA in tAp wAter, river wAter, seAwAter, And beverAge cAn be Achieved in 7 min
Jianbo Shi - One of the best experts on this subject based on the ideXlab platform.
-
binding And Activity of TetrAbromobisphenol A mono ether structurAl AnAlogs to thyroid hormone trAnsport proteins And receptors
Environmental Health Perspectives, 2020Co-Authors: Xiaomin Ren, Linlin Yao, Qiao Xue, Jianbo Shi, Qinghua Zhang, Pu Wang, Aiqian Zhang, Guibin JiangAbstract:BAckground: TetrAbromobisphenol A (TBBPA) mono-ether structurAl AnAlogs, identified As the by-products or trAnsformAtion products of commerciAl TBBPA bis-ether derivAtives, hAve been identified As ...
-
identificAtion of trAnsformAtion degrAdAtion products of TetrAbromobisphenol A And its derivAtives
Trends in Analytical Chemistry, 2019Co-Authors: Aifeng Liu, Jianbo Shi, Zongshan Zhao, Zhaoshuang Shen, Xiangfeng Liang, Guibing JiangAbstract:AbstrAct The structurAl identificAtion As well As quAntitAtive AnAlysis of trAnsformAtion And degrAdAtion (T/D) products of TetrAbromobisphenol A (TBBPA) And its derivAtives cAn provide useful informAtion on the corresponding T/D mechAnism As well As environmentAl impAct. However, it is still A greAt chAllenge to AnAlyze trAce levels of T/D products, both unknown And known products, As A result of the complexity of environmentAl mAtrices And the lAck of commerciAl/ArtificiAl stAndArd chemicAls. This criticAl review summArized the T/D model experiments, sAmple prepArAtion And the AssociAted AnAlyticAl methods, including extrAction, purificAtion, concentrAtion, derivAtizAtion, quAntitAtion AnAlysis And 14C-lAbeling technologies. Furthermore, the mAss spectrAl AnAlysis of TBBPA relAted compounds using different AnAlyticAl instruments And T/D products predicted by computer progrAms Are Also described.
-
sensitive immunoAssAy for simultAneous determinAtion of TetrAbromobisphenol A bis 2 hydroxyethyl ether And TetrAbromobisphenol A mono hydroxyethyl ether An effective And reliAble strAtegy to estimAte the typicAl TetrAbromobisphenol A derivAtive And byproduct in AquAtic environments
Environmental Pollution, 2017Co-Authors: Zhen Zhang, Nuanfei Zhu, Menglu Huang, Yaru Liang, Kun Zeng, Zhenjiang Liu, Jianbo ShiAbstract:TetrAbromobisphenol A bis(2-hydroxyethyl) ether (TBBPA DHEE), As one of the TBBPA derivAtives, is frequently Applied As A flAme retArdAnt. To dAte, however, little evidence hAs been gAthered regArding its environmentAl behAvior And fAte. This is mAinly Attributed to the lAck of An AnAlyticAl ApproAch AvAilAble to meAsure it. MAss spectrometry cAnnot determine levels of TBBPA DHEE. LC-MS could not ionize TBBPA DHEE to yield enough frAgments, while GC-MS could not be Applied for the AnAlysis either, due to the thermAl degrAdAtion of TBBPA DHEE. We here designed A novel hApten, then conjugAted it with A cArrier protein And produced A type of polyclonAl Antibody cApAble of recognizing TBBPA DHEE. BAsed on this ApproAch, A sensitive And high-throughput indirect competitive enzyme-linked immunosorbent AssAy (ELISA) wAs estAblished. The respective detection limit (LOD, bAsed on 90% B/B0) And IC50 cAlculAted from the stAndArd curve were 0.702 And 9.868 ng/mL for TBBPA DHEE. And the estAblished method showed good tolerAnce to vArious mAtrix interferents. Using our ELISA, we meAsured the concentrAtions of these substAnces from environmentAl wAter sAmples with no pretreAtment other thAn filtrAtion. We found the presence of TBBPA DHEE in environmentAl wAter sAmples collected in JiAngsu province, And the detected concentrAtions rAnging from 1.5 to 7.7 ng/mL. Our proposed method here could be Applied to completely And systemAticAlly investigAte TBBPA DHEE And TBBPA MHEE concentrAtions in environmentAl sAmples.
-
identificAtion of emerging brominAted chemicAls As the trAnsformAtion products of TetrAbromobisphenol A tbbpA derivAtives in soil
Environmental Science & Technology, 2017Co-Authors: Aifeng Liu, Jianbo Shi, Maoyong Song, Chuanyong Jing, Guibin JiangAbstract:In contrAst to the extensive investigAtion AlreAdy conducted on TetrAbromobisphenol A (TBBPA), the metAbolism of TBBPA derivAtives is still lArgely unknown. In this pAper, we chArActerized unknown brominAted compounds detected in 84 soil sAmples collected from sites Around three brominAted flAme retArdAnt production plAnts to determine possible trAnsformAtion products of TBBPA derivAtives. In Addition to tribromobisphenol A (TriBBPA), dibromobisphenol A (DBBPA), And TBBPA, six novel trAnsformAtion products, TriBBPA mono(Allyl ether) (TriBBPA-MAE), DBBPA-MAE, hydroxyl TriBBPA-MAE, TBBPA mono(2-bromo-3-hydroxypropyl ether) (TBBPA-MBHPE), TBBPA mono(2,3-dihydroxypropyl ether) (TBBPA-MDHPE), And TBBPA mono(3-hydroxypropyl ether) (TBBPA-MHPE) were identified. The detection frequencies of these identified chemicAls in soil sAmples rAnged from 17% to 89%, indicAting the widespreAd presence of the trAnsformAtion products. To uncover the possible TBBPA derivAtive trAnsformAtion pAthwAys involved, super-reduced vit...
-
silver ion post column derivAtizAtion electrosprAy ionizAtion mAss spectrometry for determinAtion of TetrAbromobisphenol A derivAtives in wAter sAmples
RSC Advances, 2015Co-Authors: Yong Tian, Huanwen Chen, Jian Chen, Jianbo Shi, Aifeng Liu, Chunxiao Liu, Eric Handberg, Guibin JiangAbstract:A rApid And sensitive method wAs developed for the identificAtion And quAntitAtion of TetrAbromobisphenol A (TBBPA) derivAtives in wAter sAmples. Six mAjor TBBPA derivAtives, including TetrAbromobisphenol A bis(2-hydroxyethyl) ether (TBBPA-BHEE), TetrAbromobisphenol A bis(glycidyl) ether (TBBPA-BGE), TetrAbromobisphenol A bis(Allyl) ether (TBBPA-BAE), TetrAbromobisphenol A mono(2-hydroxyethyl) ether (TBBPA-MHEE), TetrAbromobisphenol A mono(glycidyl) ether (TBBPA-MGE) And TetrAbromobisphenol A mono(Allyl) ether (TBBPA-MAE), were selected As the tArget compounds. By Applying the silver cAtion (Ag+) As the post-column derivAtizAtion reAgent, the TBBPA derivAtives formed complexes ([M + Ag]NO3) online, which could be effectively electrosprAyed to generAte ionic clusters ([M + Ag]+) for sensitive mAss AnAlysis. Under the optimized conditions, the 6 TBBPA derivAtives were sepArAted And detected within 10 min. The limits of detection (LODs) were between 0.16 And 1.96 μg L−1, And the lineAr rAnges extended to 200 μg L−1 (R2 ≥ 0.9957). The relAtive stAndArd deviAtions (RSDs) were less thAn 7.7% for 10 μg L−1 of the TBBPA derivAtives (n = 7). The proposed method wAs successfully Applied in AnAlysis of environmentAl wAter sAmples. The spiked recoveries rAnged from 81.3% to 114.9%, suggesting the AccurAcy And feAsibility of the method.
Aifeng Liu - One of the best experts on this subject based on the ideXlab platform.
-
screening of brominAted pyrolysis products of TetrAbromobisphenol A by integrAting controllAble heAting device with Ambient mAss spectrometry
Journal of Analytical and Applied Pyrolysis, 2020Co-Authors: Zongshan Zhao, Yong Tian, Yaqi Cai, Aifeng Liu, Huan Liu, Wei Gao, Xiangfeng Chen, Zhenhua WangAbstract:AbstrAct Pyrolysis, An effective recycle strAtegy for resins or plAstic contAining TetrAbromobisphenol A (TBBPA), often leAd to formAtion of more toxic decomposition chemicAls. Online collection coupled with off-line AnAlysis for quAlitAtive And quAntitAtive AnAlysis of the residue often induce informAtion loss of these pyrolysis products. In this study, A temperAture controllAble thermAl decomposition device coupled with An Ambient mAss spectrometry wAs directly employed for on-line monitoring of the pyrolysis process of TBBPA. ThermAl products through debrominAtion, methylAtion, methoxylAtion And β-scission hAve All been detected. BAsed on the mAss spectrA of TBBPA decomposition products, the number of bromine Atoms And the m/z vAlues, About 8 brominAted decomposition products/intermediAtes hAve been identified. TemperAture plAyed the criticAl role for the pyrolysis processes. It wAs found thAt Almost no TBBPA degrAded At low temperAture (100−150 °C), intensified decomposition hAppened At About 300 °C And smAll molecules formed in lArge quAntities At > 450 °C.
-
GlycosylAtion of TetrAbromobisphenol A in Pumpkin.
Environmental science & technology, 2019Co-Authors: Xingwang Hou, Xiaoyun Wang, Jiyan Liu, Jerald L Schnoor, Aifeng Liu, Guibin JiangAbstract:TetrAbromobisphenol A (TBBPA) is the most widely used brominAted flAme retArdAnt (BFR), And it bioAccumulAtes throughout the food chAins. Its fAte in the first trophic level, plAnts, is of speciAl interest. In this study, A four-dAy hydroponic exposure of TBBPA At A concentrAtion of 1 μmol L-1 to pumpkin seedlings wAs conducted. A nontArget screening method for hydrophilic bromine-contAining metAbolites wAs modified, bAsed on both typicAl isotope pAtterns of bromine And mAss defect, And used to process mAss spectrA dAtA. A totAl of 20 glycosylAtion And mAlonyl glycosylAtion metAbolites were found for TBBPA in the pumpkin plAnts. RepresentAtive glycosyl TBBPA reference stAndArds were synthesized to evAluAte the contribution of this glycosylAtion process. ApproximAtely 86% of pArent TBBPA wAs metAbolized to form those 20 glycosyl TBBPAs, showing thAt glycosylAtion wAs the most dominAnt metAbolism pAthwAy for TBBPA in pumpkin At the tested exposure concentrAtion.
-
identificAtion of trAnsformAtion degrAdAtion products of TetrAbromobisphenol A And its derivAtives
Trends in Analytical Chemistry, 2019Co-Authors: Aifeng Liu, Jianbo Shi, Zongshan Zhao, Zhaoshuang Shen, Xiangfeng Liang, Guibing JiangAbstract:AbstrAct The structurAl identificAtion As well As quAntitAtive AnAlysis of trAnsformAtion And degrAdAtion (T/D) products of TetrAbromobisphenol A (TBBPA) And its derivAtives cAn provide useful informAtion on the corresponding T/D mechAnism As well As environmentAl impAct. However, it is still A greAt chAllenge to AnAlyze trAce levels of T/D products, both unknown And known products, As A result of the complexity of environmentAl mAtrices And the lAck of commerciAl/ArtificiAl stAndArd chemicAls. This criticAl review summArized the T/D model experiments, sAmple prepArAtion And the AssociAted AnAlyticAl methods, including extrAction, purificAtion, concentrAtion, derivAtizAtion, quAntitAtion AnAlysis And 14C-lAbeling technologies. Furthermore, the mAss spectrAl AnAlysis of TBBPA relAted compounds using different AnAlyticAl instruments And T/D products predicted by computer progrAms Are Also described.
-
biotrAnsformAtion of TetrAbromobisphenol A dimethyl ether bAck to TetrAbromobisphenol A in whole pumpkin plAnts
Environmental Pollution, 2018Co-Authors: Xingwang Hou, Jiyan Liu, Jerald L Schnoor, Aifeng Liu, Ting Ruan, Guibin JiangAbstract:As the metAbolites of TetrAbromobisphenol A (TBBPA), TetrAbromobisphenol A mono- And di-methyl ethers (TBBPA MME And TBBPA DME) hAve been detected in vArious environmentAl mediA. However, knowledge of the contribution of plAnts to their environmentAl fAtes, especiAlly to the interActions between TBBPA DME And TBBPA, is quite limited. In this study, the metAbolism And behAviors of TBBPA DME wAs studied with pumpkin plAnts through 15-dAy hydroponic exposure. The TBBPA were Also studied sepArAtely using in-lAb hydroponic exposure for compArison. The results showed thAt more TBBPA DME AccumulAted in pumpkin roots And trAnslocAted up to stems And leAves compAred with TBBPA. TrAnsformAtion of TBBPA DME occurred lAter And more slowly thAn thAt of TBBPA. Interconversion between TBBPA DME And TBBPA wAs verified in intAct plAnts for the first time. NAmely, TBBPA DME cAn be biotrAnsformed to TBBPA MME (trAnsformAtion rAtio in mole mAss, TRMM 0.50%) And to TBBPA (TRMM 0.53%) within pumpkin; And TBBPA cAn be biotrAnsformed to TBBPA MME (TRMM 0.58%) And to TBBPA DME (TRMM 0.62%). In Addition, two single benzene-ring metAbolites, 2,6-dibromo-4-(2-(2-hydroxyl)-propyl)-Anisole (DBHPA, TRMM 3.4%) with An O-methyl group And 2,6-dibromo-4-(2-(2-hydroxyl)-propyl)-phenetole (DBHPP, TRMM 0.57%) with An O-ethyl group, were identified As the trAnsformAtion products in the TBBPA exposure experiments. The trAnsformAtion And interconversion from TBBPA DME bAck to TBBPA is reported As A new pAthwAy And potentiAl source for TBBPA in the environment.
-
UltrAsensitive DeterminAtion of TetrAbromobisphenol A by CovAlent OrgAnic FrAmework BAsed Solid PhAse MicroextrAction Coupled with ConstAnt Flow Desorption IonizAtion MAss Spectrometry
2018Co-Authors: Wei Gao, Yong Tian, Zongshan Zhao, Yaqi Cai, Aifeng Liu, Huan Liu, Guibin JiangAbstract:RApid detection of ultrAtrAce pollutAnts in complex mAtrixes is A greAt chAllenge for studying their environmentAl behAviors And impActs. In this work, A method is developed by combining covAlent orgAnic frAmework (COF) bAsed solid phAse microextrAction (SPME) with constAnt flow desorption ionizAtion mAss spectrometry for rApid detection of trAce TetrAbromobisphenol A (TBBPA) in multiple wAter mediA. The limits of detection And quAlificAtion Are 0.92 And 3.1 ng L–1 for TBBPA, respectively. The lineAr rAnge is between 0.01 And 10 μg L–1 (R2 = 0.9992), And the relAtive stAndArd deviAtions with single fiber And multiple fibers Are 6.4% And 6.7% (0.1 μg L–1, n = 9), respectively. The detection of nAnogrAm per liter levels of TBBPA in tAp wAter, river wAter, seAwAter, And beverAge cAn be Achieved in 7 min
