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David Rempel - One of the best experts on this subject based on the ideXlab platform.
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Modeling the Effect of the 2018 Revised ACGIH® Hand Activity Threshold Limit Value® (TLV) at Reducing Risk for Carpal Tunnel Syndrome
Journal of occupational and environmental hygiene, 2019Co-Authors: Marcus Yung, David Rempel, Ann Marie Dale, Jay Kapellusch, Stephen Bao, Carisa Harris-adamson, Alysha R. Meyers, Kurt T. Hegmann, Bradley A. EvanoffAbstract:AbstractRecent studies have shown the 2001 American Conference of Governmental Industrial Hygienists (ACGIH®) Threshold Limit Value (TLV®) for Hand Activity was not sufficiently protective for work...
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s02 1 associations between force repetition posture duty cycle Threshold Limit Value for hand activity level tlv for hal and risk of carpal tunnel syndrome
Occupational and Environmental Medicine, 2016Co-Authors: Jay Kapellusch, Carisa Harrisadamson, David RempelAbstract:Carpal tunnel syndrome (CTS) is a costly disease for employers and a source of long-term disability to workers. Force, repetition, and deviated posture are commonly believed risk factors for CTS. The aim of this study was to quantify associations between workplace biomechanical factors and incidence of dominant-hand CTS after adjusting for personal risk factors. 2751 incident eligible workers were followed prospectively for up to 6.4 years and contributed 6243 person-years of data to this longitudinal study. Applied force, frequency and duty cycle of exertions, wrist posture, and ACGIH TLV for HAL were quantified for each worker and periodically remeasured throughout the study. Incident cases of CTS were determined from symptoms and electrodiagnostic studies. Hazard Ratios were estimated using proportional hazards regression. All models were adjusted for age, gender, BMI, and orthogonal physical exposures. In the adjusted models, associations were found between CTS and peak force (HR = 2.17; 95% CI: 1.38 to 3.43), frequency of forceful exertions (HR = 1.84; 95% CI: 1.19 to 2.86),% of time spent in forceful exertions (HR = 2.05; 95% CI: 1.34 to 3.15), and the TLV for HAL as a continuous variable (HR = 1.32 per unit; 95% CI: 1.11–1.57). Conversely, statistical associations with increased risk of CTS were not found between total frequency of, or total% time under exertions, nor for deviated wrist postures. These results suggest that peak force acts as an independent risk factor for CTS. However, frequency of exertion and% time under exertion are only associated with CTS when a non-trivial amount of force is being applied, thus “repetition” does not appear to be an independent risk factor per se. We found no evidence to suggest that hand/wrist posture is an independent risk factor for CTS.
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a frequency duty cycle equation for the acgih hand activity level
Ergonomics, 2015Co-Authors: Robert G Radwin, Thomas J Armstrong, David P Azari, Mary J Lindstrom, Sheryl S Ulin, David RempelAbstract:A new equation for predicting the hand activity level (HAL) used in the American Conference for Government Industrial Hygienists Threshold Limit Value® (TLV®) was based on exertion frequency (F) and percentage duty cycle (D). The TLV® includes a table for estimating HAL from F and D originating from data in Latko et al. (Latko WA, Armstrong TJ, Foulke JA, Herrin GD, Rabourn RA, Ulin SS, Development and evaluation of an observational method for assessing repetition in hand tasks. American Industrial Hygiene Association Journal, 58(4):278–285, 1997) and post hoc adjustments that include extrapolations outside of the data range. Multimedia video task analysis determined D for two additional jobs from Latko's study not in the original data-set, and a new nonlinear regression equation was developed to better fit the data and create a more accurate table. The equation, , generally matches the TLV® HAL lookup table, and is a substantial improvement over the linear model, particularly for F>1.25 Hz and D>60% jobs...
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1st place premus best paper competition workplace and individual factors in wrist tendinosis among blue collar workers the san francisco study
Scandinavian Journal of Work Environment & Health, 2011Co-Authors: Carisa Harris, Ellen A Eisen, Robert J Goldberg, Niklas Krause, David RempelAbstract:Results During the 481 person-years of follow-up, there were 26 incident cases of right wrist tendinosis [incidence rate (IR) 5.40 cases per 100 person-years]. Adjusting for age, gender, and repetition, wrist tendinosis was associated with % time spent in heavy pinch [hazard ratio (HR) 5.01, 95% CI 1.27–19.79]. Composite exposure measure American Conference of Industrial Hygienists Threshold Limit Value (ACGIH-TLV) for hand activity level (HR 3.95, 95% CI 1.52-10.26) was also associated with the outcome for the medium-exposure group using video-based total repetition rate. Conclusions The workplace factors predicting wrist tendinosis were time-weighted average Values of % time spent in heavy pinch and the ACGIH-TLV for Hand Activity Level. The % time spent in power grip was not a significant predictor, nor were any measures of repetition. An exposure−response relationship was observed for the % time spent in heavy pinch. These findings may improve programs for preventing occupational wrist tendinosis. Key terms exposure–response; force; MSD; musculoskeletal disorder; occupational; prospective study; repetition; upper extremity.
Jay Kapellusch - One of the best experts on this subject based on the ideXlab platform.
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Modeling the Effect of the 2018 Revised ACGIH® Hand Activity Threshold Limit Value® (TLV) at Reducing Risk for Carpal Tunnel Syndrome
Journal of occupational and environmental hygiene, 2019Co-Authors: Marcus Yung, David Rempel, Ann Marie Dale, Jay Kapellusch, Stephen Bao, Carisa Harris-adamson, Alysha R. Meyers, Kurt T. Hegmann, Bradley A. EvanoffAbstract:AbstractRecent studies have shown the 2001 American Conference of Governmental Industrial Hygienists (ACGIH®) Threshold Limit Value (TLV®) for Hand Activity was not sufficiently protective for work...
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s02 1 associations between force repetition posture duty cycle Threshold Limit Value for hand activity level tlv for hal and risk of carpal tunnel syndrome
Occupational and Environmental Medicine, 2016Co-Authors: Jay Kapellusch, Carisa Harrisadamson, David RempelAbstract:Carpal tunnel syndrome (CTS) is a costly disease for employers and a source of long-term disability to workers. Force, repetition, and deviated posture are commonly believed risk factors for CTS. The aim of this study was to quantify associations between workplace biomechanical factors and incidence of dominant-hand CTS after adjusting for personal risk factors. 2751 incident eligible workers were followed prospectively for up to 6.4 years and contributed 6243 person-years of data to this longitudinal study. Applied force, frequency and duty cycle of exertions, wrist posture, and ACGIH TLV for HAL were quantified for each worker and periodically remeasured throughout the study. Incident cases of CTS were determined from symptoms and electrodiagnostic studies. Hazard Ratios were estimated using proportional hazards regression. All models were adjusted for age, gender, BMI, and orthogonal physical exposures. In the adjusted models, associations were found between CTS and peak force (HR = 2.17; 95% CI: 1.38 to 3.43), frequency of forceful exertions (HR = 1.84; 95% CI: 1.19 to 2.86),% of time spent in forceful exertions (HR = 2.05; 95% CI: 1.34 to 3.15), and the TLV for HAL as a continuous variable (HR = 1.32 per unit; 95% CI: 1.11–1.57). Conversely, statistical associations with increased risk of CTS were not found between total frequency of, or total% time under exertions, nor for deviated wrist postures. These results suggest that peak force acts as an independent risk factor for CTS. However, frequency of exertion and% time under exertion are only associated with CTS when a non-trivial amount of force is being applied, thus “repetition” does not appear to be an independent risk factor per se. We found no evidence to suggest that hand/wrist posture is an independent risk factor for CTS.
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exposure response relationships for the acgih Threshold Limit Value for hand activity level results from a pooled data study of carpal tunnel syndrome
Scandinavian Journal of Work Environment & Health, 2014Co-Authors: Jay Kapellusch, Ellen A Eisen, Ann Marie Dale, Stephen Bao, Arun Garg, Elizabeth J Malloy, Frederic E Gerr, Carisa Harrisadamson, Susan Burt, Bradley A. EvanoffAbstract:Objectives This paper aimed to quantify exposure–response relationships between the American Conference of Governmental Industrial Hygienists’ (ACGIH) Threshold Limit Value (TLV) for hand-activity level (HAL) and incidence of carpal tunnel syndrome (CTS). Methods Manufacturing and service workers previously studied by six research institutions had their data combined and re-analyzed. CTS cases were defined by symptoms and abnormal nerve conduction. Hazard ratios (HR) were calculated using proportional hazards regression after adjusting for age, gender, body mass index, and CTS predisposing conditions. Results The longitudinal study comprised 2751 incident-eligible workers, followed prospectively for up to 6.4 years and contributing 6243 person-years of data. Associations were found between CTS and TLV for HAL both as a continuous variable [HR 1.32 per unit, 95% confidence interval (95% CI) 1.11–1.57] and when categorized using the ACGIH action Limit (AL) and TLV. Those between the AL and TLV and above the TLV had HR of 1.7 (95% CI 1.2–2.5) and 1.5 (95% CI 1.0–2.1), respectively. As independent variables (in the same adjusted model) the HR for peak force (PF) and HAL were 1.14 per unit (95% CI 1.05–1.25), and 1.04 per unit (95% CI 0.93–1.15), respectively. Conclusion Those with exposures above the AL were at increased risk of CTS, but there was no further increase in risk for workers above the TLV. This suggests that the current AL may not be sufficiently protective of workers. Combinations of PF and HAL are useful for predicting risk of CTS.
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pooling job physical exposure data from multiple independent studies in a consortium study of carpal tunnel syndrome
Ergonomics, 2013Co-Authors: Jay Kapellusch, Ann Marie Dale, Stephen Bao, Bradley A. Evanoff, Barbara Silverstein, Arun Garg, Frederic E Gerr, Carisa Harrisadamson, Susan Burt, Kurt T. HegmannAbstract:Pooling data from different epidemiological studies of musculoskeletal disorders (MSDs) is necessary to improve statistical power and to more precisely quantify exposure–response relationships for MSDs. The pooling process is difficult and time-consuming, and small methodological differences could lead to different exposure–response relationships. A sub-committee of a six-study research consortium studying carpal tunnel syndrome: (i) visited each study site, (ii) documented methods used to collect physical exposure data and (iii) determined compatibility of exposure variables across studies. Certain measures of force, frequency of exertion and duty cycle were collected by all studies and were largely compatible. A portion of studies had detailed data to investigate simultaneous combinations of force, frequency and duration of exertions. Limited compatibility was found for hand/wrist posture. Only two studies could calculate compatible Strain Index scores, but Threshold Limit Value for Hand Activity Level ...
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the strain index si and Threshold Limit Value tlv for hand activity level hal risk of carpal tunnel syndrome cts in a prospective cohort
Ergonomics, 2012Co-Authors: Arun Garg, Jay Kapellusch, Kurt T. Hegmann, Jacqueline J Wertsch, Andrew Merryweather, Gwen Deckowschaefer, Elizabeth J MalloyAbstract:A cohort of 536 workers was enrolled from 10 diverse manufacturing facilities and was followed monthly for six years. Job physical exposures were individually measured. Worker demographics, medical history, psychosocial factors, current musculoskeletal disorders (MSDs) and nerve conduction studies (NCS) were obtained. Point and lifetime prevalence of carpal tunnel syndrome (CTS) at baseline (symptoms + abnormal NCS) were 10.3% and 19.8%. During follow-up, there were 35 new CTS cases (left, right or both hands). Factors predicting development of CTS included: job physical exposure (American conference of governmental industrial hygienists Threshold Limit Value (ACGIH TLV) for Hand Activity Level (HAL) and the Strain Index (SI)), age, BMI, other MSDs, inflammatory arthritis, gardening outside of work and feelings of depression. In the adjusted models, the TLV for HAL and the SI were both significant per unit increase in exposure with hazard ratios (HR) increasing up to a maximum of 5.4 (p = 0.05) and 5.3 (p...
Bradley A. Evanoff - One of the best experts on this subject based on the ideXlab platform.
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Modeling the Effect of the 2018 Revised ACGIH® Hand Activity Threshold Limit Value® (TLV) at Reducing Risk for Carpal Tunnel Syndrome
Journal of occupational and environmental hygiene, 2019Co-Authors: Marcus Yung, David Rempel, Ann Marie Dale, Jay Kapellusch, Stephen Bao, Carisa Harris-adamson, Alysha R. Meyers, Kurt T. Hegmann, Bradley A. EvanoffAbstract:AbstractRecent studies have shown the 2001 American Conference of Governmental Industrial Hygienists (ACGIH®) Threshold Limit Value (TLV®) for Hand Activity was not sufficiently protective for work...
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exposure response relationships for the acgih Threshold Limit Value for hand activity level results from a pooled data study of carpal tunnel syndrome
Scandinavian Journal of Work Environment & Health, 2014Co-Authors: Jay Kapellusch, Ellen A Eisen, Ann Marie Dale, Stephen Bao, Arun Garg, Elizabeth J Malloy, Frederic E Gerr, Carisa Harrisadamson, Susan Burt, Bradley A. EvanoffAbstract:Objectives This paper aimed to quantify exposure–response relationships between the American Conference of Governmental Industrial Hygienists’ (ACGIH) Threshold Limit Value (TLV) for hand-activity level (HAL) and incidence of carpal tunnel syndrome (CTS). Methods Manufacturing and service workers previously studied by six research institutions had their data combined and re-analyzed. CTS cases were defined by symptoms and abnormal nerve conduction. Hazard ratios (HR) were calculated using proportional hazards regression after adjusting for age, gender, body mass index, and CTS predisposing conditions. Results The longitudinal study comprised 2751 incident-eligible workers, followed prospectively for up to 6.4 years and contributing 6243 person-years of data. Associations were found between CTS and TLV for HAL both as a continuous variable [HR 1.32 per unit, 95% confidence interval (95% CI) 1.11–1.57] and when categorized using the ACGIH action Limit (AL) and TLV. Those between the AL and TLV and above the TLV had HR of 1.7 (95% CI 1.2–2.5) and 1.5 (95% CI 1.0–2.1), respectively. As independent variables (in the same adjusted model) the HR for peak force (PF) and HAL were 1.14 per unit (95% CI 1.05–1.25), and 1.04 per unit (95% CI 0.93–1.15), respectively. Conclusion Those with exposures above the AL were at increased risk of CTS, but there was no further increase in risk for workers above the TLV. This suggests that the current AL may not be sufficiently protective of workers. Combinations of PF and HAL are useful for predicting risk of CTS.
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pooling job physical exposure data from multiple independent studies in a consortium study of carpal tunnel syndrome
Ergonomics, 2013Co-Authors: Jay Kapellusch, Ann Marie Dale, Stephen Bao, Bradley A. Evanoff, Barbara Silverstein, Arun Garg, Frederic E Gerr, Carisa Harrisadamson, Susan Burt, Kurt T. HegmannAbstract:Pooling data from different epidemiological studies of musculoskeletal disorders (MSDs) is necessary to improve statistical power and to more precisely quantify exposure–response relationships for MSDs. The pooling process is difficult and time-consuming, and small methodological differences could lead to different exposure–response relationships. A sub-committee of a six-study research consortium studying carpal tunnel syndrome: (i) visited each study site, (ii) documented methods used to collect physical exposure data and (iii) determined compatibility of exposure variables across studies. Certain measures of force, frequency of exertion and duty cycle were collected by all studies and were largely compatible. A portion of studies had detailed data to investigate simultaneous combinations of force, frequency and duration of exertions. Limited compatibility was found for hand/wrist posture. Only two studies could calculate compatible Strain Index scores, but Threshold Limit Value for Hand Activity Level ...
Carisa Harrisadamson - One of the best experts on this subject based on the ideXlab platform.
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s02 1 associations between force repetition posture duty cycle Threshold Limit Value for hand activity level tlv for hal and risk of carpal tunnel syndrome
Occupational and Environmental Medicine, 2016Co-Authors: Jay Kapellusch, Carisa Harrisadamson, David RempelAbstract:Carpal tunnel syndrome (CTS) is a costly disease for employers and a source of long-term disability to workers. Force, repetition, and deviated posture are commonly believed risk factors for CTS. The aim of this study was to quantify associations between workplace biomechanical factors and incidence of dominant-hand CTS after adjusting for personal risk factors. 2751 incident eligible workers were followed prospectively for up to 6.4 years and contributed 6243 person-years of data to this longitudinal study. Applied force, frequency and duty cycle of exertions, wrist posture, and ACGIH TLV for HAL were quantified for each worker and periodically remeasured throughout the study. Incident cases of CTS were determined from symptoms and electrodiagnostic studies. Hazard Ratios were estimated using proportional hazards regression. All models were adjusted for age, gender, BMI, and orthogonal physical exposures. In the adjusted models, associations were found between CTS and peak force (HR = 2.17; 95% CI: 1.38 to 3.43), frequency of forceful exertions (HR = 1.84; 95% CI: 1.19 to 2.86),% of time spent in forceful exertions (HR = 2.05; 95% CI: 1.34 to 3.15), and the TLV for HAL as a continuous variable (HR = 1.32 per unit; 95% CI: 1.11–1.57). Conversely, statistical associations with increased risk of CTS were not found between total frequency of, or total% time under exertions, nor for deviated wrist postures. These results suggest that peak force acts as an independent risk factor for CTS. However, frequency of exertion and% time under exertion are only associated with CTS when a non-trivial amount of force is being applied, thus “repetition” does not appear to be an independent risk factor per se. We found no evidence to suggest that hand/wrist posture is an independent risk factor for CTS.
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exposure response relationships for the acgih Threshold Limit Value for hand activity level results from a pooled data study of carpal tunnel syndrome
Scandinavian Journal of Work Environment & Health, 2014Co-Authors: Jay Kapellusch, Ellen A Eisen, Ann Marie Dale, Stephen Bao, Arun Garg, Elizabeth J Malloy, Frederic E Gerr, Carisa Harrisadamson, Susan Burt, Bradley A. EvanoffAbstract:Objectives This paper aimed to quantify exposure–response relationships between the American Conference of Governmental Industrial Hygienists’ (ACGIH) Threshold Limit Value (TLV) for hand-activity level (HAL) and incidence of carpal tunnel syndrome (CTS). Methods Manufacturing and service workers previously studied by six research institutions had their data combined and re-analyzed. CTS cases were defined by symptoms and abnormal nerve conduction. Hazard ratios (HR) were calculated using proportional hazards regression after adjusting for age, gender, body mass index, and CTS predisposing conditions. Results The longitudinal study comprised 2751 incident-eligible workers, followed prospectively for up to 6.4 years and contributing 6243 person-years of data. Associations were found between CTS and TLV for HAL both as a continuous variable [HR 1.32 per unit, 95% confidence interval (95% CI) 1.11–1.57] and when categorized using the ACGIH action Limit (AL) and TLV. Those between the AL and TLV and above the TLV had HR of 1.7 (95% CI 1.2–2.5) and 1.5 (95% CI 1.0–2.1), respectively. As independent variables (in the same adjusted model) the HR for peak force (PF) and HAL were 1.14 per unit (95% CI 1.05–1.25), and 1.04 per unit (95% CI 0.93–1.15), respectively. Conclusion Those with exposures above the AL were at increased risk of CTS, but there was no further increase in risk for workers above the TLV. This suggests that the current AL may not be sufficiently protective of workers. Combinations of PF and HAL are useful for predicting risk of CTS.
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pooling job physical exposure data from multiple independent studies in a consortium study of carpal tunnel syndrome
Ergonomics, 2013Co-Authors: Jay Kapellusch, Ann Marie Dale, Stephen Bao, Bradley A. Evanoff, Barbara Silverstein, Arun Garg, Frederic E Gerr, Carisa Harrisadamson, Susan Burt, Kurt T. HegmannAbstract:Pooling data from different epidemiological studies of musculoskeletal disorders (MSDs) is necessary to improve statistical power and to more precisely quantify exposure–response relationships for MSDs. The pooling process is difficult and time-consuming, and small methodological differences could lead to different exposure–response relationships. A sub-committee of a six-study research consortium studying carpal tunnel syndrome: (i) visited each study site, (ii) documented methods used to collect physical exposure data and (iii) determined compatibility of exposure variables across studies. Certain measures of force, frequency of exertion and duty cycle were collected by all studies and were largely compatible. A portion of studies had detailed data to investigate simultaneous combinations of force, frequency and duration of exertions. Limited compatibility was found for hand/wrist posture. Only two studies could calculate compatible Strain Index scores, but Threshold Limit Value for Hand Activity Level ...
Alain Hartmann - One of the best experts on this subject based on the ideXlab platform.
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development and evaluation of a method for the quantification of airborne thermoactinomyces vulgaris by real time pcr
Journal of Microbiological Methods, 2013Co-Authors: Laetitia Betelli, Philippe Duquenne, Frederic Grenouillet, Xavier Simon, Emeline Scherer, Evelyne Gehin, Alain HartmannAbstract:Abstract Actinomycetes are ubiquitous and some can be potentially pathogenic for humans when present in the air of some working areas. It's notably the case for Thermoactinomyces vulgaris in composting facilities where aerial concentrations can reach high Values of more than 10 7 CFU·m − 3 . Workers exposure to these inhalable bioaerosols can be the source of various diseases. The literature reveals a lack of knowledge about risk assessment: there is neither dose–effects relationship for most agents, or Threshold Limit Value. The objectives of this study were to develop and standardize a method to quantify workers exposure to bioaerosols. We have developed and evaluated a method to quantify airborne T . vulgaris based on DNA extraction of aerial microbial communities and qPCR. Four DNA extraction protocols were compared, and primers and a hydrolysis probe were designed for specific amplification of the target species ( gyrB gene). This method was compared to traditional methods based on viable or cultivable counting by epifluorescence microscopy or plating on selective media. The method was applied on environmental bioaerosols sampled under real exposure conditions in composting plants. We demonstrate that the method to quantify T. vulgaris in bioaerosols is specific, sensitive and repeatable. We demonstrate the occurrence and quantified T . vulgaris in the atmosphere of composting facilities with concentrations ranging from 3 × 10 2 to 3 × 10 6 × m − 3 .
