The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform

Hiroya Kitano - One of the best experts on this subject based on the ideXlab platform.

  • A case report of Thyroid Metastasis from p16-positive oropharyngeal squamous cell carcinoma.
    Endocrine journal, 2018
    Co-Authors: Masao Takenobu, Sueyoshi Moritani, Kana Yoshioka, Tsuyoshi Morisaki, Hiroya Kitano
    Abstract:

    Thyroid Metastasis from head and neck squamous cell carcinoma (SCC) is a very rare form of rarely observed metastatic Thyroid tumor. We herein report a case of Thyroid Metastasis from oropharyngeal SCC (OSCC). The patient was a 68-year-old male diagnosed with p16-positive tonsillar OSCC on the right side with multiple lymph node metastases and a Thyroid mass, which was determined as metastatic p16-positive OSCC by immunohistochemistry of specimens collected by fine-needle aspiration cytology (FNAC). He received one cycle of induction chemotherapy followed by concurrent chemoradiotherapy. No visible primary lesions were observed after treatment. The disappearance of the tonsillar lesion was considered to be a complete response by the magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET-CT). The Thyroid lesion was also decreased, but a solid lesion with unclear boundaries in the right Thyroid lobe remained. Therefore, the patient underwent total Thyroidectomy to remove any residual tumor. Postoperative pathological evaluation revealed no residual viable carcinoma cells in the resected specimen. As illustrated in this case, immunohistochemistry of the FNAC specimen for p16 was successful in determining the Thyroid tumor as a metastatic lesion from the oropharynx. Although radical radiotherapy might be sufficient to control Thyroid gland Metastasis of OSCC, in this case, early-stage remedial surgery was thought to be necessary for a secure radical cure.

Young Kee Shong - One of the best experts on this subject based on the ideXlab platform.

  • Metastasis to the Thyroid diagnosed by fine needle aspiration biopsy
    Clinical Endocrinology, 2005
    Co-Authors: Gyungyub Gong, Suck Joon Hong, Young Kee Shong
    Abstract:

    Summary Background  Metastasis to the Thyroid is uncommon, but the number of cases seems to have increased in recent years. This increase may be related to more frequent use of fine-needle aspiration biopsy (FNAB) in any suspected case. Design  A retrospective review of patients with Thyroid Metastasis diagnosed by FNAB at the Asan Medical Centre. Patients  Twenty-two patients who were seen at the Asan Medical Centre between 1997 and 2003. Median age was 55 years with range between 34 and 74 years. Results  Fourteen patients presented with a palpable Thyroid nodule. Eight patients had an impalpable Thyroid nodule that was found incidentally during the various imaging studies. The breast (five patients) was the most common primary site followed by the kidney (three), colon (three) and lung (three). FNAB confirmed metastatic disease in 19 patients and raised suspicion in three patients. The suspicion of Metastasis to the Thyroid was confirmed by Tru-cut needle core biopsy in one patient and surgery in two patients. Thyroid metastases were found during the initial work-up for primary tumour in eight patients. In the remaining 14 patients, the interval from diagnosis of primary tumour to the detection of Thyroid Metastasis varied from 8 months to 15 years, with a median of 54 months. Fifteen patients had metastatic disease elsewhere at the time of presentation. Ten patients received chemotherapy. Radiotherapy was used in two patients. Seven patients are still alive, with one patient disease free for 16 months following resection of the Thyroid Metastasis. Conclusions  Thyroid metastases are uncommon but can be detected more frequently with routine use of FNAB. Breast cancer is the most common tumour that metastasizes to the Thyroid. They usually occur when there are metastases elsewhere, sometimes many years after the diagnosis of the original primary tumour and show poor prognosis in general.

  • Metastasis to the Thyroid diagnosed by fine‐needle aspiration biopsy
    Clinical endocrinology, 2005
    Co-Authors: Tae Yong Kim, Gyungyub Gong, Suck Joon Hong, Won Bae Kim, Young Kee Shong
    Abstract:

    Summary Background  Metastasis to the Thyroid is uncommon, but the number of cases seems to have increased in recent years. This increase may be related to more frequent use of fine-needle aspiration biopsy (FNAB) in any suspected case. Design  A retrospective review of patients with Thyroid Metastasis diagnosed by FNAB at the Asan Medical Centre. Patients  Twenty-two patients who were seen at the Asan Medical Centre between 1997 and 2003. Median age was 55 years with range between 34 and 74 years. Results  Fourteen patients presented with a palpable Thyroid nodule. Eight patients had an impalpable Thyroid nodule that was found incidentally during the various imaging studies. The breast (five patients) was the most common primary site followed by the kidney (three), colon (three) and lung (three). FNAB confirmed metastatic disease in 19 patients and raised suspicion in three patients. The suspicion of Metastasis to the Thyroid was confirmed by Tru-cut needle core biopsy in one patient and surgery in two patients. Thyroid metastases were found during the initial work-up for primary tumour in eight patients. In the remaining 14 patients, the interval from diagnosis of primary tumour to the detection of Thyroid Metastasis varied from 8 months to 15 years, with a median of 54 months. Fifteen patients had metastatic disease elsewhere at the time of presentation. Ten patients received chemotherapy. Radiotherapy was used in two patients. Seven patients are still alive, with one patient disease free for 16 months following resection of the Thyroid Metastasis. Conclusions  Thyroid metastases are uncommon but can be detected more frequently with routine use of FNAB. Breast cancer is the most common tumour that metastasizes to the Thyroid. They usually occur when there are metastases elsewhere, sometimes many years after the diagnosis of the original primary tumour and show poor prognosis in general.

Sang Eun Kim - One of the best experts on this subject based on the ideXlab platform.

Yanzhen Wang - One of the best experts on this subject based on the ideXlab platform.

  • Ultrasonographic characteristics of Thyroid Metastasis from clear cell renal cell carcinoma: A case report.
    Medicine, 2020
    Co-Authors: Peng Tian, Xiaoxi Liu, Xiaoyue Rong, Zekai Zhang, Yanzhen Wang
    Abstract:

    Introduction Thyroid Metastasis from clear cell renal cell carcinoma (ccRCC) is a very rare condition, and its ultrasonographic characteristics have not been summarized in the literature. We herein report a case of Thyroid Metastasis from ccRCC that occurred 11 years after the surgery and the ultrasonographic characteristics of it are described. Patient concerns A 57-year-old male patient was admitted to our hospital in September 2018 due to discomfort in the neck. No other abnormalities were found during laboratory examination of Thyroid function. The previous medical history of the patient included a right nephrectomy for the treatment of ccRCC in June 2007. Diagnosis Ultrasound examinations revealed multiple Thyroid nodules. After nephrectomy, there was no obvious abnormality in the right renal area. Computed tomography (CT) showed an oval lesion with slightly lower density in the right lobe of the Thyroid, and the patient was initially diagnosed with nodular goiter. Interventions Bilateral partial Thyroidectomy under general anesthesia was conducted. Intraoperative frozen pathological examination showed clear cell carcinoma in the right lobe of the Thyroid gland. Therefore, total Thyroidectomy and lymph node dissection in the central neck area were performed. Outcomes The patient underwent surgical treatment and recovered successfully. The patient was followed up for 2 years with no further Metastasis. Conclusion Ultrasound examination is a safe and convenient screening method. For patients with a renal malignant tumor, if the ultrasound image of Thyroid nodule is found to have the characteristics of malignant tumors, the occurrence of Metastasis of renal cancer to the Thyroid should be highly suspected. Core needle biopsy (CNB) and histopathological diagnosis should be conducted subsequently for early diagnosis.

Mei-yu Fang - One of the best experts on this subject based on the ideXlab platform.

  • Thyroid Metastasis from non small cell lung cancer
    International Journal of Clinical and Experimental Pathology, 2019
    Co-Authors: Jun Cao, Jia-ni Shi, Mei-yu Fang
    Abstract:

    Non-Thyroid malignancies to the Thyroid gland resulting from distant metastases are extremely rare, and such cases are rarely seen in clinical settings. The question of how a tumor metastasizes to the Thyroid remains unanswered. Here we report a case of lung adenocarcinoma metastasizing to the Thyroid gland. The article covers the pathological features, treatments, examination reports, and the postoperative follow-up reviews of the patient. In this article, we discuss the diagnostic method, the spread route, the prognosis, the mechanism and above all, the treatment. In addition, we searched the PubMed and ISI Web of Science databases for articles published in English using the key words "lung", "Thyroid", and "Metastasis", and we reviewed nearly all the reports about Thyroid malignancies being metastasized from lung cancer. This rare case emphasizes the importance of the multifaceted comprehensiveness of the cephalometry diagnosis, pathological diagnosis, and immunohistochemical analysis to ensure that such rare cases are not missed. We declare that all cases of Thyroid malignancies metastasized from the lungs shall be reported at large for further clinical research.

  • Thyroid Metastasis from chondrosarcoma.
    Medicine, 2019
    Co-Authors: Jin-yao Dai, Jia-ni Shi, Mei-yu Fang, Jun Cao
    Abstract:

    For chondrosarcoma, Metastasis to the Thyroid gland is extremely rare. The diagnosis and treatment of Thyroid Metastasis from chondrosarcoma are discussed here.We found a case of Thyroid malignancy occurring after treatment of chondrosarcoma. We reviewed patient characteristics, histological presentations on initial chondrosarcoma and Thyroid Metastasis, treatments, times of recurrence and death. In addition, we searched Embase, PubMed, and ISI Web of Science databases (1996-2018) for articles published in the English language using the key words "chondrosarcoma" and "Thyroid" and we reviewed almost all the reports about Thyroid Metastasis from chondrosarcoma.Only 5 cases of chondrosarcoma metastases in the Thyroid gland have been reported in the literature. We found that most patients are adults, with compression signs or pain, most of whom have poor prognoses. The main examinations are ultrasound, CT and fine needle aspiration biopsy, and primary treatment is surgery.These rare cases of chondrosarcoma presenting as a Metastasis in the Thyroid gland highlight the importance of close communication between radiologists, histopathologists, and clinicians to ensure that such exceptional cases are not missed.