The Experts below are selected from a list of 204 Experts worldwide ranked by ideXlab platform

Joana Cabete - One of the best experts on this subject based on the ideXlab platform.

  • Adult Tinea capitis and Tinea barbae in a tertiary Portuguese hospital: A 11-year audit.
    Mycoses, 2019
    Co-Authors: Bruno Duarte, Célia Galhardas, Joana Cabete
    Abstract:

    Adult Tinea capitis and Tinea barbae are nowadays considered uncommon in developed countries. Despite their potential for morbidity and healthcare costs, few series have attempted to characterise these infectious disorders. We conducted a cross-sectional study to analyse the epidemiological, clinical and mycological characteristics of adult Tinea capitis and Tinea barbae of a large tertiary centre in Southern Europe. All adult patients with a mycological-confirmed Tinea capitis or barbae over a 11-year period (January 2008 to December 2018) were considered for the analysis. Concerning Tinea capitis, 860 culture-confirmed diagnoses were made during this 11-year period, of which only 15 (1.5%) occurred in adults (15 patients). A disproportionately high number of patients were female and immunocompromised. Microsporum audouinii (20%) and Trichophyton rubrum (20%) were the most common isolates. Half of the cases were initially misdiagnosed. Regarding Tinea barbae, 7 cases were diagnosed over this time period. Overuse of topical steroids was widespread in this population. Trichophyton rubrum was the infectious agent in all cases. Initial misdiagnosis was very common (43%). Adult Tinea capitis and Tinea barbae can still be observed in contemporary practice and remain a public health concern, with the immunosuppressed patient being particularly affected. Initial misdiagnosis is a common occurrence. Anthropophilic fungi are now the most common aetiologic agents of these infections, and they will probably continue to do so as the large urban centres expand peripherally. Awareness for this diagnosis is necessary to prevent unwarranted morbidity and costs.

Clara Romano - One of the best experts on this subject based on the ideXlab platform.

  • Microsporum gypseum infection in the Siena area in 2005-2006.
    Mycoses, 2008
    Co-Authors: Clara Romano, L. Massai, A. Gallo, Michele Fimiani
    Abstract:

    Fourteen cases of dermatophytosis caused by Microsporum gypseum, representing 6.8% of all dermatophytic infections reported, were diagnosed in Siena, Italy, between 2005 and 2006. There were as follows: six cases of Tinea corporis, one case of Tinea corporis associated with Tinea capitis, one case of Tinea corporis associated with Tinea barbae, one kerion on the head, one Tinea cruris, one Tinea faciei, one Tinea barbae, two onychomycosis. In the three subjects with Tinea corporis, the clinical appearance was impetigo-like, psoriasis-like and pityriasis rosea-like respectively. In another case, the lesion was indicative of Tinea imbricata. The diagnosis was based on mycological examination. In six cases, the source of infection was a cat, whereas in the others it was contact with soil.

  • Six cases of infection due to Trichophyton verrucosum
    Mycoses, 2001
    Co-Authors: Clara Romano, L. Massai, C. Gianni, Carlo Crosti
    Abstract:

    Dermatophyte infections due to Trichophyton verrucosum are not frequent in Europe. Six cases observed in Italy in the period 1995-99 are reported. Two were cases of Tinea barbae, two of Tinea corporis and two of Tinea capitis, one of which had been preceded by Tinea faciei. In three cases the source of contagion was horses, in two it was cattle and in one case it was another person. The two cases of Tinea barbae were initially interpreted and treated as bacterial infections, a diagnostic error reported with increasing frequency in the literature regarding dermatophytosis due to T. verrucosum.

Carlo Crosti - One of the best experts on this subject based on the ideXlab platform.

  • Six cases of infection due to Trichophyton verrucosum
    Mycoses, 2001
    Co-Authors: Clara Romano, L. Massai, C. Gianni, Carlo Crosti
    Abstract:

    Dermatophyte infections due to Trichophyton verrucosum are not frequent in Europe. Six cases observed in Italy in the period 1995-99 are reported. Two were cases of Tinea barbae, two of Tinea corporis and two of Tinea capitis, one of which had been preceded by Tinea faciei. In three cases the source of contagion was horses, in two it was cattle and in one case it was another person. The two cases of Tinea barbae were initially interpreted and treated as bacterial infections, a diagnostic error reported with increasing frequency in the literature regarding dermatophytosis due to T. verrucosum.

P Nenoff - One of the best experts on this subject based on the ideXlab platform.

  • Tinea barbae profunda due to trichophyton mentagrophytes case report and review
    Hautarzt, 2019
    Co-Authors: Henriette Kirsten, Jennifer Haiduk, P Nenoff, Silke Uhrlas, Mirjana Ziemer, Janchristoph Simon
    Abstract:

    Bei der Tinea barbae handelt es sich um eine seltene Dermatomykose, die per definitionem follikular gebunden im Bartbereich erwachsener Manner auftritt. Der Hautbefund beginnt meist mit Erythemen mit Schuppung. Bei Progredienz oder Ausbreitung an Terminalhaaren in die Tiefe kommt es zu Follikulitiden mit Pustel- und Knotenbildung sowie Abszedierungen mit fest anhaftenden gelblichen Krusten, begleitet von einer lokoregionaren Lymphknotenschwellung und gelegentlich vermindertem Allgemeinzustand oder (sub)febrilen Temperaturen. Dies fuhrt haufig zunachst zur Verdachtsdiagnose einer bakteriellen Folliculitis barbae oder Impetigo contagiosa. Die Tinea barbae wird meist durch Spezies der Gattung Trichophyton (T.) ausgelost. Die Erreger sind vielfaltig und gehoren uberwiegend zu den zoophilen, nur gelegentlich zu anthropophilen und selten zu den geophilen Dermatophyten. Mithilfe der gezielten Anamnese und Diagnostik in Form von mykologischen Untersuchungen, Histologie und molekularbiologischem Dermatophytennachweis mittels Polymerasekettenreaktion kann heute schnell die Diagnose einer Tinea barbae, bei unserem Patienten ausgelost durch T. mentagrophytes, gestellt werden. Bei zeitnaher und ausreichend langer Therapie kommt es zur vollstandigen Restitutio ad integrum.

  • deep facial mycosis due to trichophyton verrucosum molecular genetic identification of the dermatophyte in paraffin embedded tissue case report and review of the literature
    Mycoses, 2018
    Co-Authors: Uwe Wollina, Silke Uhrlas, C Kruger, G Hansel, Jacqueline Schonlebe, Utachristina Hipler, P Nenoff
    Abstract:

    Deep trichophytosis is relatively uncommon. The infection of the bearded area is also known as sycosis barbae or Tinea barbae and can be caused by various fungal species, most often zoophilic fungi. We report on an 80-year-old male patient with severe sycosis barbae who had no animal contact and was treated with systemic antibiosis without improvement. Microbial and mycological investigations using swabs from oozing lesions revealed Staphylococcus hemolyticus and Candida parapsilosis. Histology demonstrated fungal elements in hair follicles. Paraffin-embedded material was subjected to further mycological analysis. For molecular diagnostics DNA was prepared from paraffin sections for real-time polymerase chain reaction (RT-PCR). For sequencing, DNA was isolated from paraffin-embedded skin tissue and the ITS region of the rDNA was selected. Sequencing of the ITS2 region of rRNA revealed a 100% accordance with Trichophyton (T.) verrucosum. Treatment with oral terbinafine achieved a complete remission. Sycosis barbae is an important differential diagnosis for infections of the bearded area. Nucleic acid amplification techniques (NAAT) are more and more used for direct examination of dermatophytes in clinical samples, e. g. T. verrucosum. NAAT are also used as culture confirmation tests for identification of rare dermatophytes like T. verrucosum. Today, singleplex and multiplex quantitative real-time PCR (qRT-PCR) assays for the detection of the most common dermatophytes including T. verrucosum in clinical specimens are available. Recently, an ITS2 PCR assay has been succefully used for direct detection of T. verrucosum in paraffin-embedded formalin fixed skin tissue. The PCR is fast and highly specific. The sensitivity of direct molecular detection of the dermatophytes both in native clinical material, and in paraffin-embedded skin tissue can been increased. This article is protected by copyright. All rights reserved.

  • Tinea barbae profunda due to trichophyton mentagrophytes after journey to thailand case report and review
    Hautarzt, 2017
    Co-Authors: G Wendrockshiga, Silke Uhrlas, D Mechtel, Daniela Koch, C Kruger, P Nenoff
    Abstract:

    Die Tinea barbae ist eine sehr seltene Dermatophytose. Hier wird eine Tinea barbae profunda als Folge einer Reise nach Sudostasien beschrieben. Ein Geschaftsmann erkrankte nach einer Thailand-Reise an einer foudroyant verlaufenden abszedierenden Infektion im Oberlippen- und Bartbereich. Die anfangliche Therapie mit Aciclovir p. o. und Ciprofloxacin p. o., spater Ampicillin + Sulbactam i. v., war erfolglos. In einer Probeexzision war histologisch mittels Grocott-Gomori-Methenamin-Silber-Farbung Pilzmyzel erkennbar. Daraufhin wurde mit Terbinafin 250 mg uber ca. 4 Wochen behandelt, topisch mit 1 % Ciclopiroxolamin-haltiger Creme. In der Pilzkultur wuchs Trichophyton (T.) mentagrophytes. Zwischenzeitlich erkrankte die deutsche Ehefrau des Patienten an einer Tinea faciei. Aus Hautschuppen von der Wange lies sich ebenfalls T. mentagrophytes anzuchten. Der zoophile Dermatophyt war identisch mit anderen aktuell in Deutschland gefundenen zoophilen Stammen von T. mentagrophytes, die ebenfalls in Thailand erworben wurden. Der Patient hatte in Thailand Kontakt zu Female Sexworkern, die als potenzielle Infektionsquelle der Dermatophytose angesehen werden konnen. Tierkontakt bestand nicht. Die Infektionskette der Dermatophytose aus Thailand reichte wahrscheinlich von der thailandischen Sexworkerin uber den hier vorgestellten Patienten bis zu seiner Ehefrau in Deutschland. Dieser Infektionsweg ist erst seit 1 bis 2 Jahren bekannt, bislang wurden in Deutschland, der Schweiz und Osterreich jedoch ausschlieslich pubogenitale Infektionen (Tinea genitalis profunda) durch T. mentagrophytes nach Sudostasien-Reisen beschrieben. Zur Behandlung mussen oral verabreichte Antimykotika eingesetzt werden, an erster Stelle kommt Terbinafin in Betracht, alternativ Fluconazol oder Itraconazol.

Kensei Katsuoka - One of the best experts on this subject based on the ideXlab platform.