The Experts below are selected from a list of 168 Experts worldwide ranked by ideXlab platform

Toshihiko Iizasa - One of the best experts on this subject based on the ideXlab platform.

  • A surgical case of synchronous solitary splenic metastasis from lung squamous cell carcinoma: report of a case and review of the literature
    General Thoracic and Cardiovascular Surgery, 2020
    Co-Authors: Kazuhisa Tanaka, Shigetoshi Yoshida, Takekazu Iwata, Kai Nishii, Yukiko Matsui, Takahiro Sugiyama, Makiko Itami, Toshihiko Iizasa
    Abstract:

    Solitary splenic metastasis is an extremely rare event. We herein report a surgical case of a solitary splenic metastasis from lung cancer. A 78-year-old man presented with abdominal pain. Abdominal computed tomography (CT) showed splenic rupture. Coil embolization to the splenic artery was performed, and the patient’s condition improved. Chest CT showed a 5-cm lung mass in the right upper lobe, suggesting lung cancer with splenic metastasis. Transbronchial Aspiration cytology showed squamous cell carcinoma of the lung. We diagnosed the patient with lung cancer (cT2bN0M1b [spleen only] stage IVA) and performed splenectomy and right upper lobectomy separately. Both lesions were squamous cell carcinoma and positive for p40. Thus, primary lung squamous cell carcinoma and solitary splenic metastasis were diagnosed. The patient was still alive without recurrence 15 months postoperatively. We herein report a rare case of lung squamous cell carcinoma with solitary splenic metastasis and review the literature.

  • Transbronchial fine needle Aspiration cytological examination: a useful tool for diagnosing primary lung cancer.
    The Thoracic and cardiovascular surgeon, 2006
    Co-Authors: Akira Iyoda, Yasumitsu Moriya, Kazuhiro Yasufuku, Toshihiko Iizasa, Yasuo Sekine, Masayuki Baba, Kazutoshi Shibuya, Kenzo Hiroshima, Yukio Nakatani, Takehiko Fujisawa
    Abstract:

    BACKGROUND Obtaining a definitive preoperative diagnosis plays a critical role in deciding upon the treatment approach for lung carcinoma. However, success in making definitive diagnoses of small primary lung cancers will require new approaches because these cancers are difficult to detect using standard biopsy procedures. METHODS We evaluated the results of morphologic definitive diagnosis together with various clinical factors in 1003 primary lung cancers resected surgically. Patients underwent Transbronchial brushing, fine needle Aspiration cytology, forceps biopsy, and/or forceps biopsy-stamp cytology for preoperative diagnoses, in conjunction with the use of Diff-Quik to confirm that hits had been made on the radiographic shadows before terminating the examinations. RESULTS Sensitivities of the diagnostic procedures for primary lung cancers were as follows: 64.8% for brushing, 56.1% for Transbronchial forceps biopsy, 72.0% for Transbronchial forceps biopsy-stamp cytology, and 86.4% for Transbronchial fine needle Aspiration. The four Transbronchial biopsy procedures had a combined overall sensitivity of 92.7%. In patients with peripheral lung cancers of 2 cm or less in diameter, Transbronchial fine needle Aspiration had a sensitivity of 75.9%, which was the highest sensitivity for all Transbronchial examinations. In the subset of 296 patients who underwent all four Transbronchial biopsy examinations, Transbronchial fine needle Aspiration had the highest sensitivity of preoperative diagnosis of all the Transbronchial examination methods. CONCLUSIONS The sensitivity of preoperative cytological diagnosis for primary lung cancers, especially Transbronchial Aspiration cytology, is high. Transbronchial fine needle Aspiration cytology is useful for the preoperative diagnosis of primary lung cancer.

  • Endobronchial ultrasound using a new convex probe: a preliminary study on surgically resected specimens.
    Oncology reports, 2004
    Co-Authors: Kazuhiro Yasufuku, Akira Iyoda, Masako Chiyo, Shigetoshi Yoshida, Kiyoshi Shibuya, Yasuo Sekine, Prashant N. Chhajed, Takahiro Nakajima, Mizuto Otsuji, Toshihiko Iizasa
    Abstract:

    The radial endobronchial ultrasound (EBUS) probe is conventionally inserted through the working channel of the flexible bronchoscope and limits interventional diagnostics and therapeutics under direct ultrasound control. The aim of this study was to assess the new convex probe EBUS (CP-EBUS) in the visualization of the hilar lymph nodes in surgically resected specimens and explore its feasibility to perform Transbronchial needle Aspiration (TBNA) under direct EBUS guidance prior to its clinical use. Fourteen surgically resected specimens from lung cancer (n=12) and metastatic lung cancer (n=2) patients were included in the study. The resected specimens included eight right upper lobes, one right middle lobe, and five left lower lobes. The EBUS examination was performed with a flexible bronchoscope equipped with a 7.5 MHz convex probe (CP) that scans parallel to the insertion direction of the bronchoscope. The appearance of the hilar lymph nodes using this CP-EBUS was noted. The size of hilar lymph nodes was measured at CP-EBUS and compared with the actual size of the lymph nodes, which was measured with a Vernier's caliper. Hilar lymph nodes could be clearly visualized with CP-EBUS. There was a good correlation between the actual size of the lymph node and that measured using CP-EBUS (R 2 =0.950). A dedicated Transbronchial Aspiration needle could be inserted into the hilar lymph node under direct ultrasonic control. There is a possibility in the underestimation of the size of large lymph nodes due to the scanning nature of the convex probe. The CP-EBUS was successfully used to visualize the hilar lymph node and perform TBNA in surgical resected lung specimens. This technique has an excellent potential to perform direct ultrasound guided TBNA of mediastinal and hilar lymph nodes.

  • A new thin-type bronchoscope improves diagnostic accuracy of peripheral pulmonary carcinoma
    Oncology Reports, 2003
    Co-Authors: Akira Iyoda, Makoto Suzuki, Masako Chiyo, Yasumitsu Moriya, Kazuhiro Yasufuku, Shigetoshi Yoshida, Kiyoshi Shibuya, Toshihiko Iizasa, Yasuo Sekine, Yukio Saitoh
    Abstract:

    We investigated the XBF-4B40 (4B40) thin bronchoscope, which has a 4.0-mm outer diameter and a 2.0-mm biopsy channel, and studied its impact on the diagnosis of lung carcinoma. We analyzed 30 peripheral lung carcinoma cases by performing bronchoscopic examination using the 4B40 and the type 200 videoscope and recorded the most distal bronchus level reached. In addition, Transbronchial Aspiration biopsy, forceps biopsy, or brushing was performed, and the diagnosis accuracy between the two instruments was determined. The mean of the most distal bronchus reached by the 4B40 and the type 200 videoscope was the 4.5th and the 3rd, respectively. The 4B40 reached significantly further into the distal bronchus than the type 200 videoscope (p

Akira Iyoda - One of the best experts on this subject based on the ideXlab platform.

  • Transbronchial fine needle Aspiration cytological examination: a useful tool for diagnosing primary lung cancer.
    The Thoracic and cardiovascular surgeon, 2006
    Co-Authors: Akira Iyoda, Yasumitsu Moriya, Kazuhiro Yasufuku, Toshihiko Iizasa, Yasuo Sekine, Masayuki Baba, Kazutoshi Shibuya, Kenzo Hiroshima, Yukio Nakatani, Takehiko Fujisawa
    Abstract:

    BACKGROUND Obtaining a definitive preoperative diagnosis plays a critical role in deciding upon the treatment approach for lung carcinoma. However, success in making definitive diagnoses of small primary lung cancers will require new approaches because these cancers are difficult to detect using standard biopsy procedures. METHODS We evaluated the results of morphologic definitive diagnosis together with various clinical factors in 1003 primary lung cancers resected surgically. Patients underwent Transbronchial brushing, fine needle Aspiration cytology, forceps biopsy, and/or forceps biopsy-stamp cytology for preoperative diagnoses, in conjunction with the use of Diff-Quik to confirm that hits had been made on the radiographic shadows before terminating the examinations. RESULTS Sensitivities of the diagnostic procedures for primary lung cancers were as follows: 64.8% for brushing, 56.1% for Transbronchial forceps biopsy, 72.0% for Transbronchial forceps biopsy-stamp cytology, and 86.4% for Transbronchial fine needle Aspiration. The four Transbronchial biopsy procedures had a combined overall sensitivity of 92.7%. In patients with peripheral lung cancers of 2 cm or less in diameter, Transbronchial fine needle Aspiration had a sensitivity of 75.9%, which was the highest sensitivity for all Transbronchial examinations. In the subset of 296 patients who underwent all four Transbronchial biopsy examinations, Transbronchial fine needle Aspiration had the highest sensitivity of preoperative diagnosis of all the Transbronchial examination methods. CONCLUSIONS The sensitivity of preoperative cytological diagnosis for primary lung cancers, especially Transbronchial Aspiration cytology, is high. Transbronchial fine needle Aspiration cytology is useful for the preoperative diagnosis of primary lung cancer.

  • Endobronchial ultrasound using a new convex probe: a preliminary study on surgically resected specimens.
    Oncology reports, 2004
    Co-Authors: Kazuhiro Yasufuku, Akira Iyoda, Masako Chiyo, Shigetoshi Yoshida, Kiyoshi Shibuya, Yasuo Sekine, Prashant N. Chhajed, Takahiro Nakajima, Mizuto Otsuji, Toshihiko Iizasa
    Abstract:

    The radial endobronchial ultrasound (EBUS) probe is conventionally inserted through the working channel of the flexible bronchoscope and limits interventional diagnostics and therapeutics under direct ultrasound control. The aim of this study was to assess the new convex probe EBUS (CP-EBUS) in the visualization of the hilar lymph nodes in surgically resected specimens and explore its feasibility to perform Transbronchial needle Aspiration (TBNA) under direct EBUS guidance prior to its clinical use. Fourteen surgically resected specimens from lung cancer (n=12) and metastatic lung cancer (n=2) patients were included in the study. The resected specimens included eight right upper lobes, one right middle lobe, and five left lower lobes. The EBUS examination was performed with a flexible bronchoscope equipped with a 7.5 MHz convex probe (CP) that scans parallel to the insertion direction of the bronchoscope. The appearance of the hilar lymph nodes using this CP-EBUS was noted. The size of hilar lymph nodes was measured at CP-EBUS and compared with the actual size of the lymph nodes, which was measured with a Vernier's caliper. Hilar lymph nodes could be clearly visualized with CP-EBUS. There was a good correlation between the actual size of the lymph node and that measured using CP-EBUS (R 2 =0.950). A dedicated Transbronchial Aspiration needle could be inserted into the hilar lymph node under direct ultrasonic control. There is a possibility in the underestimation of the size of large lymph nodes due to the scanning nature of the convex probe. The CP-EBUS was successfully used to visualize the hilar lymph node and perform TBNA in surgical resected lung specimens. This technique has an excellent potential to perform direct ultrasound guided TBNA of mediastinal and hilar lymph nodes.

  • A new thin-type bronchoscope improves diagnostic accuracy of peripheral pulmonary carcinoma
    Oncology Reports, 2003
    Co-Authors: Akira Iyoda, Makoto Suzuki, Masako Chiyo, Yasumitsu Moriya, Kazuhiro Yasufuku, Shigetoshi Yoshida, Kiyoshi Shibuya, Toshihiko Iizasa, Yasuo Sekine, Yukio Saitoh
    Abstract:

    We investigated the XBF-4B40 (4B40) thin bronchoscope, which has a 4.0-mm outer diameter and a 2.0-mm biopsy channel, and studied its impact on the diagnosis of lung carcinoma. We analyzed 30 peripheral lung carcinoma cases by performing bronchoscopic examination using the 4B40 and the type 200 videoscope and recorded the most distal bronchus level reached. In addition, Transbronchial Aspiration biopsy, forceps biopsy, or brushing was performed, and the diagnosis accuracy between the two instruments was determined. The mean of the most distal bronchus reached by the 4B40 and the type 200 videoscope was the 4.5th and the 3rd, respectively. The 4B40 reached significantly further into the distal bronchus than the type 200 videoscope (p

Kazuhiro Yasufuku - One of the best experts on this subject based on the ideXlab platform.

  • Transbronchial fine needle Aspiration cytological examination: a useful tool for diagnosing primary lung cancer.
    The Thoracic and cardiovascular surgeon, 2006
    Co-Authors: Akira Iyoda, Yasumitsu Moriya, Kazuhiro Yasufuku, Toshihiko Iizasa, Yasuo Sekine, Masayuki Baba, Kazutoshi Shibuya, Kenzo Hiroshima, Yukio Nakatani, Takehiko Fujisawa
    Abstract:

    BACKGROUND Obtaining a definitive preoperative diagnosis plays a critical role in deciding upon the treatment approach for lung carcinoma. However, success in making definitive diagnoses of small primary lung cancers will require new approaches because these cancers are difficult to detect using standard biopsy procedures. METHODS We evaluated the results of morphologic definitive diagnosis together with various clinical factors in 1003 primary lung cancers resected surgically. Patients underwent Transbronchial brushing, fine needle Aspiration cytology, forceps biopsy, and/or forceps biopsy-stamp cytology for preoperative diagnoses, in conjunction with the use of Diff-Quik to confirm that hits had been made on the radiographic shadows before terminating the examinations. RESULTS Sensitivities of the diagnostic procedures for primary lung cancers were as follows: 64.8% for brushing, 56.1% for Transbronchial forceps biopsy, 72.0% for Transbronchial forceps biopsy-stamp cytology, and 86.4% for Transbronchial fine needle Aspiration. The four Transbronchial biopsy procedures had a combined overall sensitivity of 92.7%. In patients with peripheral lung cancers of 2 cm or less in diameter, Transbronchial fine needle Aspiration had a sensitivity of 75.9%, which was the highest sensitivity for all Transbronchial examinations. In the subset of 296 patients who underwent all four Transbronchial biopsy examinations, Transbronchial fine needle Aspiration had the highest sensitivity of preoperative diagnosis of all the Transbronchial examination methods. CONCLUSIONS The sensitivity of preoperative cytological diagnosis for primary lung cancers, especially Transbronchial Aspiration cytology, is high. Transbronchial fine needle Aspiration cytology is useful for the preoperative diagnosis of primary lung cancer.

  • Endobronchial ultrasound using a new convex probe: a preliminary study on surgically resected specimens.
    Oncology reports, 2004
    Co-Authors: Kazuhiro Yasufuku, Akira Iyoda, Masako Chiyo, Shigetoshi Yoshida, Kiyoshi Shibuya, Yasuo Sekine, Prashant N. Chhajed, Takahiro Nakajima, Mizuto Otsuji, Toshihiko Iizasa
    Abstract:

    The radial endobronchial ultrasound (EBUS) probe is conventionally inserted through the working channel of the flexible bronchoscope and limits interventional diagnostics and therapeutics under direct ultrasound control. The aim of this study was to assess the new convex probe EBUS (CP-EBUS) in the visualization of the hilar lymph nodes in surgically resected specimens and explore its feasibility to perform Transbronchial needle Aspiration (TBNA) under direct EBUS guidance prior to its clinical use. Fourteen surgically resected specimens from lung cancer (n=12) and metastatic lung cancer (n=2) patients were included in the study. The resected specimens included eight right upper lobes, one right middle lobe, and five left lower lobes. The EBUS examination was performed with a flexible bronchoscope equipped with a 7.5 MHz convex probe (CP) that scans parallel to the insertion direction of the bronchoscope. The appearance of the hilar lymph nodes using this CP-EBUS was noted. The size of hilar lymph nodes was measured at CP-EBUS and compared with the actual size of the lymph nodes, which was measured with a Vernier's caliper. Hilar lymph nodes could be clearly visualized with CP-EBUS. There was a good correlation between the actual size of the lymph node and that measured using CP-EBUS (R 2 =0.950). A dedicated Transbronchial Aspiration needle could be inserted into the hilar lymph node under direct ultrasonic control. There is a possibility in the underestimation of the size of large lymph nodes due to the scanning nature of the convex probe. The CP-EBUS was successfully used to visualize the hilar lymph node and perform TBNA in surgical resected lung specimens. This technique has an excellent potential to perform direct ultrasound guided TBNA of mediastinal and hilar lymph nodes.

  • A new thin-type bronchoscope improves diagnostic accuracy of peripheral pulmonary carcinoma
    Oncology Reports, 2003
    Co-Authors: Akira Iyoda, Makoto Suzuki, Masako Chiyo, Yasumitsu Moriya, Kazuhiro Yasufuku, Shigetoshi Yoshida, Kiyoshi Shibuya, Toshihiko Iizasa, Yasuo Sekine, Yukio Saitoh
    Abstract:

    We investigated the XBF-4B40 (4B40) thin bronchoscope, which has a 4.0-mm outer diameter and a 2.0-mm biopsy channel, and studied its impact on the diagnosis of lung carcinoma. We analyzed 30 peripheral lung carcinoma cases by performing bronchoscopic examination using the 4B40 and the type 200 videoscope and recorded the most distal bronchus level reached. In addition, Transbronchial Aspiration biopsy, forceps biopsy, or brushing was performed, and the diagnosis accuracy between the two instruments was determined. The mean of the most distal bronchus reached by the 4B40 and the type 200 videoscope was the 4.5th and the 3rd, respectively. The 4B40 reached significantly further into the distal bronchus than the type 200 videoscope (p

Shigetoshi Yoshida - One of the best experts on this subject based on the ideXlab platform.

  • A surgical case of synchronous solitary splenic metastasis from lung squamous cell carcinoma: report of a case and review of the literature
    General Thoracic and Cardiovascular Surgery, 2020
    Co-Authors: Kazuhisa Tanaka, Shigetoshi Yoshida, Takekazu Iwata, Kai Nishii, Yukiko Matsui, Takahiro Sugiyama, Makiko Itami, Toshihiko Iizasa
    Abstract:

    Solitary splenic metastasis is an extremely rare event. We herein report a surgical case of a solitary splenic metastasis from lung cancer. A 78-year-old man presented with abdominal pain. Abdominal computed tomography (CT) showed splenic rupture. Coil embolization to the splenic artery was performed, and the patient’s condition improved. Chest CT showed a 5-cm lung mass in the right upper lobe, suggesting lung cancer with splenic metastasis. Transbronchial Aspiration cytology showed squamous cell carcinoma of the lung. We diagnosed the patient with lung cancer (cT2bN0M1b [spleen only] stage IVA) and performed splenectomy and right upper lobectomy separately. Both lesions were squamous cell carcinoma and positive for p40. Thus, primary lung squamous cell carcinoma and solitary splenic metastasis were diagnosed. The patient was still alive without recurrence 15 months postoperatively. We herein report a rare case of lung squamous cell carcinoma with solitary splenic metastasis and review the literature.

  • Endobronchial ultrasound using a new convex probe: a preliminary study on surgically resected specimens.
    Oncology reports, 2004
    Co-Authors: Kazuhiro Yasufuku, Akira Iyoda, Masako Chiyo, Shigetoshi Yoshida, Kiyoshi Shibuya, Yasuo Sekine, Prashant N. Chhajed, Takahiro Nakajima, Mizuto Otsuji, Toshihiko Iizasa
    Abstract:

    The radial endobronchial ultrasound (EBUS) probe is conventionally inserted through the working channel of the flexible bronchoscope and limits interventional diagnostics and therapeutics under direct ultrasound control. The aim of this study was to assess the new convex probe EBUS (CP-EBUS) in the visualization of the hilar lymph nodes in surgically resected specimens and explore its feasibility to perform Transbronchial needle Aspiration (TBNA) under direct EBUS guidance prior to its clinical use. Fourteen surgically resected specimens from lung cancer (n=12) and metastatic lung cancer (n=2) patients were included in the study. The resected specimens included eight right upper lobes, one right middle lobe, and five left lower lobes. The EBUS examination was performed with a flexible bronchoscope equipped with a 7.5 MHz convex probe (CP) that scans parallel to the insertion direction of the bronchoscope. The appearance of the hilar lymph nodes using this CP-EBUS was noted. The size of hilar lymph nodes was measured at CP-EBUS and compared with the actual size of the lymph nodes, which was measured with a Vernier's caliper. Hilar lymph nodes could be clearly visualized with CP-EBUS. There was a good correlation between the actual size of the lymph node and that measured using CP-EBUS (R 2 =0.950). A dedicated Transbronchial Aspiration needle could be inserted into the hilar lymph node under direct ultrasonic control. There is a possibility in the underestimation of the size of large lymph nodes due to the scanning nature of the convex probe. The CP-EBUS was successfully used to visualize the hilar lymph node and perform TBNA in surgical resected lung specimens. This technique has an excellent potential to perform direct ultrasound guided TBNA of mediastinal and hilar lymph nodes.

  • A new thin-type bronchoscope improves diagnostic accuracy of peripheral pulmonary carcinoma
    Oncology Reports, 2003
    Co-Authors: Akira Iyoda, Makoto Suzuki, Masako Chiyo, Yasumitsu Moriya, Kazuhiro Yasufuku, Shigetoshi Yoshida, Kiyoshi Shibuya, Toshihiko Iizasa, Yasuo Sekine, Yukio Saitoh
    Abstract:

    We investigated the XBF-4B40 (4B40) thin bronchoscope, which has a 4.0-mm outer diameter and a 2.0-mm biopsy channel, and studied its impact on the diagnosis of lung carcinoma. We analyzed 30 peripheral lung carcinoma cases by performing bronchoscopic examination using the 4B40 and the type 200 videoscope and recorded the most distal bronchus level reached. In addition, Transbronchial Aspiration biopsy, forceps biopsy, or brushing was performed, and the diagnosis accuracy between the two instruments was determined. The mean of the most distal bronchus reached by the 4B40 and the type 200 videoscope was the 4.5th and the 3rd, respectively. The 4B40 reached significantly further into the distal bronchus than the type 200 videoscope (p

Yasuo Sekine - One of the best experts on this subject based on the ideXlab platform.

  • Transbronchial fine needle Aspiration cytological examination: a useful tool for diagnosing primary lung cancer.
    The Thoracic and cardiovascular surgeon, 2006
    Co-Authors: Akira Iyoda, Yasumitsu Moriya, Kazuhiro Yasufuku, Toshihiko Iizasa, Yasuo Sekine, Masayuki Baba, Kazutoshi Shibuya, Kenzo Hiroshima, Yukio Nakatani, Takehiko Fujisawa
    Abstract:

    BACKGROUND Obtaining a definitive preoperative diagnosis plays a critical role in deciding upon the treatment approach for lung carcinoma. However, success in making definitive diagnoses of small primary lung cancers will require new approaches because these cancers are difficult to detect using standard biopsy procedures. METHODS We evaluated the results of morphologic definitive diagnosis together with various clinical factors in 1003 primary lung cancers resected surgically. Patients underwent Transbronchial brushing, fine needle Aspiration cytology, forceps biopsy, and/or forceps biopsy-stamp cytology for preoperative diagnoses, in conjunction with the use of Diff-Quik to confirm that hits had been made on the radiographic shadows before terminating the examinations. RESULTS Sensitivities of the diagnostic procedures for primary lung cancers were as follows: 64.8% for brushing, 56.1% for Transbronchial forceps biopsy, 72.0% for Transbronchial forceps biopsy-stamp cytology, and 86.4% for Transbronchial fine needle Aspiration. The four Transbronchial biopsy procedures had a combined overall sensitivity of 92.7%. In patients with peripheral lung cancers of 2 cm or less in diameter, Transbronchial fine needle Aspiration had a sensitivity of 75.9%, which was the highest sensitivity for all Transbronchial examinations. In the subset of 296 patients who underwent all four Transbronchial biopsy examinations, Transbronchial fine needle Aspiration had the highest sensitivity of preoperative diagnosis of all the Transbronchial examination methods. CONCLUSIONS The sensitivity of preoperative cytological diagnosis for primary lung cancers, especially Transbronchial Aspiration cytology, is high. Transbronchial fine needle Aspiration cytology is useful for the preoperative diagnosis of primary lung cancer.

  • Endobronchial ultrasound using a new convex probe: a preliminary study on surgically resected specimens.
    Oncology reports, 2004
    Co-Authors: Kazuhiro Yasufuku, Akira Iyoda, Masako Chiyo, Shigetoshi Yoshida, Kiyoshi Shibuya, Yasuo Sekine, Prashant N. Chhajed, Takahiro Nakajima, Mizuto Otsuji, Toshihiko Iizasa
    Abstract:

    The radial endobronchial ultrasound (EBUS) probe is conventionally inserted through the working channel of the flexible bronchoscope and limits interventional diagnostics and therapeutics under direct ultrasound control. The aim of this study was to assess the new convex probe EBUS (CP-EBUS) in the visualization of the hilar lymph nodes in surgically resected specimens and explore its feasibility to perform Transbronchial needle Aspiration (TBNA) under direct EBUS guidance prior to its clinical use. Fourteen surgically resected specimens from lung cancer (n=12) and metastatic lung cancer (n=2) patients were included in the study. The resected specimens included eight right upper lobes, one right middle lobe, and five left lower lobes. The EBUS examination was performed with a flexible bronchoscope equipped with a 7.5 MHz convex probe (CP) that scans parallel to the insertion direction of the bronchoscope. The appearance of the hilar lymph nodes using this CP-EBUS was noted. The size of hilar lymph nodes was measured at CP-EBUS and compared with the actual size of the lymph nodes, which was measured with a Vernier's caliper. Hilar lymph nodes could be clearly visualized with CP-EBUS. There was a good correlation between the actual size of the lymph node and that measured using CP-EBUS (R 2 =0.950). A dedicated Transbronchial Aspiration needle could be inserted into the hilar lymph node under direct ultrasonic control. There is a possibility in the underestimation of the size of large lymph nodes due to the scanning nature of the convex probe. The CP-EBUS was successfully used to visualize the hilar lymph node and perform TBNA in surgical resected lung specimens. This technique has an excellent potential to perform direct ultrasound guided TBNA of mediastinal and hilar lymph nodes.

  • A new thin-type bronchoscope improves diagnostic accuracy of peripheral pulmonary carcinoma
    Oncology Reports, 2003
    Co-Authors: Akira Iyoda, Makoto Suzuki, Masako Chiyo, Yasumitsu Moriya, Kazuhiro Yasufuku, Shigetoshi Yoshida, Kiyoshi Shibuya, Toshihiko Iizasa, Yasuo Sekine, Yukio Saitoh
    Abstract:

    We investigated the XBF-4B40 (4B40) thin bronchoscope, which has a 4.0-mm outer diameter and a 2.0-mm biopsy channel, and studied its impact on the diagnosis of lung carcinoma. We analyzed 30 peripheral lung carcinoma cases by performing bronchoscopic examination using the 4B40 and the type 200 videoscope and recorded the most distal bronchus level reached. In addition, Transbronchial Aspiration biopsy, forceps biopsy, or brushing was performed, and the diagnosis accuracy between the two instruments was determined. The mean of the most distal bronchus reached by the 4B40 and the type 200 videoscope was the 4.5th and the 3rd, respectively. The 4B40 reached significantly further into the distal bronchus than the type 200 videoscope (p