The Experts below are selected from a list of 5841 Experts worldwide ranked by ideXlab platform
Eric C Poulin - One of the best experts on this subject based on the ideXlab platform.
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are Transverse Colon cancers suitable for laparoscopic resection
Surgical Endoscopy and Other Interventional Techniques, 2007Co-Authors: Christopher M Schlachta, Joseph Mamazza, Eric C PoulinAbstract:Background The large randomized trials reporting on laparoscopic versus open Colon surgery for cancer have all excluded patients with Transverse Colon cancer lesions. This study was undertaken to review our experience with surgery for curable Transverse Colon cancer.
Hideki Ohdan - One of the best experts on this subject based on the ideXlab platform.
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surgical techniques for advanced Transverse Colon cancer using the pincer approach of the Transverse mesoColon
Surgical Endoscopy and Other Interventional Techniques, 2019Co-Authors: Hiroyuki Egi, Ikki Nakashima, Minoru Hattori, Shoichiro Mukai, Masatoshi Kochi, Kazuhiro Taguchi, Haruki Sada, Yusuke Sumi, Hideki OhdanAbstract:Background Laparoscopic surgery for colorectal cancer, not only early cancer but also advanced cancer, has become standardized by some randomized controlled studies. However, cases involving advanced Transverse Colon cancer were excluded from these studies due to the technical difficulty of the surgery. Hence, laparoscopic surgery for advanced Transverse Colon cancer is still a theme that we need to overcome. To solve these issues, it is necessary to establish a standardized approach and surgical technique.
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Spontaneous regression of Transverse Colon cancer with high-frequency microsatellite instability: a case report and literature review
BMC, 2019Co-Authors: Nozomi Karakuchi, Hiroyuki Egi, Hideki Ohdan, Manabu Shimomura, Kazuhiro Toyota, Takao Hinoi, Hideki Yamamoto, Seiji Sadamoto, Koichi Mandai, Tadateru TakahashiAbstract:Abstract Background Spontaneous regression (SR) of colorectal cancer (CRC) is extremely rare, and only few cases have been reported. Although it is not yet clarified, a plausible mechanism for SR of CRC is an immunological event. Case presentation In this report, we present the case of SR of primary CRC in a 78-year-old man. Preoperative Colonoscopy was performed, and a type 2 tumor measuring 30 mm in diameter in the Transverse Colon was detected. The biopsy revealed a poorly differentiated adenocarcinoma. Colectomy was performed 2 months after initial Colonoscopy. During the surgery, only a 10-mm ulcer harboring a polypoid lesion measuring 8.5 mm was detected in the resected tissue; no other masses or carcinoma cells were seen on histological examination. Afterwards, the biopsy specimens were reanalyzed, and immunohistological analysis verified this as adenocarcinoma with stroma-infiltrating lymphocytes. Further analysis revealed a loss of two mismatch repair proteins, suggesting sporadic high-frequency microsatellite instability (MSI-H). Conclusion According to previous literature, a common site of SR in CRC is the proximal Colon, which is a feature of MSI-H CRC. However, our report showed a rare case of SR of CRC, which was in the Transverse Colon, with MSI-H present. This report indicates a relationship between immunological features of MSI-H and the occurrence of SR of CRC. A better understanding of this phenomenon and the mechanisms involved will have significant preventive and therapeutic implications for CRC, including anti-PD-1 immune checkpoint inhibitor therapy
Masashi Yamamoto - One of the best experts on this subject based on the ideXlab platform.
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optimal surgery for mid Transverse Colon cancer laparoscopic extended right hemicolectomy versus laparoscopic Transverse colectomy
World Journal of Surgery, 2018Co-Authors: Takeru Matsuda, Yasuo Sumi, Kimihiro Yamashita, Hiroshi Hasegawa, Masashi Yamamoto, Yoshiko Matsuda, Shingo Kanaji, Taro Oshikiri, Tetsu Nakamura, Satoshi SuzukiAbstract:Although the feasibility and safety of laparoscopic surgery for Transverse Colon cancer have been shown by the recent studies, the optimal laparoscopic approach for mid-Transverse Colon cancer is controversial. We retrospectively analyzed the data of patients with the mid-Transverse Colon cancer at our institutions between January 2007 and April 2017. Thirty-eight and 34 patients who received extended right hemicolectomy and Transverse colectomy, respectively, were enrolled. There were no significant differences in operating time, blood loss, and hospital stay between the two groups. Postoperative complications developed in 10 of 34 patients (29.4%; wound infection: 2 cases, anastomotic leakage: 2 cases, bowel obstruction: 1 case, incisional hernia: 2 cases, others: 3 cases) for the Transverse colectomy group and in 4 of 38 patients (10.5%; wound infection: 1 case, anastomotic leakage: 0 case, bowel obstruction: 2 cases, incisional hernia: 0 case, others: 1 case) for the extended right hemicolectomy group (P = 0.014). Although the median number of harvested #221 and #222 LNs was similar between the two groups (6 vs. 8, P = 0.710, and 3 vs. 2, P = 0.256, respectively), that of #223 was significantly larger in extended right hemicolectomy than in Transverse colectomy (3 vs. 1, P = 0.038). The 5-year disease-free and overall survival rates were 92.4 and 90.3% for the extended right hemicolectomy group, and 95.7 and 79.6% for the Transverse colectomy group (P = 0.593 and P = 0.638, respectively). Laparoscopic extended right hemicolectomy and laparoscopic Transverse colectomy offer similar oncological outcomes for mid-Transverse Colon cancer. Laparoscopic extended right hemicolectomy might be associated with fewer postoperative complications.
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laparoscopic resection of Transverse Colon cancer at splenic flexure technical aspects and results
Updates in Surgery, 2016Co-Authors: Junji Okuda, Masashi Yamamoto, Keitaro Tanaka, Shinsuke Masubuchi, Kazuhisa UchiyamaAbstract:Laparoscopic resection of Transverse Colon cancer at splenic flexure is technical demanding and its efficacy remains controversial. The aim of this study was to investigate its technical aspects such as pitfalls and overcoming them, and to demonstrate the short-term and oncologic long-term outcomes. To overcome the difficulty in laparoscopic resection of Transverse Colon cancer at splenic flexure, we recognized the following technical tips as essential. First of all, we have to precisely identify major vessels variations feeding tumor. Secondary, anatomical dissection of mesoColon through medial approach is indispensible. Third, safe takedown of splenic flexure to fully mobilization of left hemiColon is mandatory. This cohort study analyzed 95 patients with stage II (43) and III (52) underwent resection of Transverse Colon cancer at splenic flexure. 61 laparoscopic surgeries (LAC) and 34 conventional open surgeries (OC) from December 1996 to December 2009 were evaluated. Short-term and oncologic long-term outcomes were recorded. Operative time was longer in LAC. However, blood loss was less, recovery of bowel function and hospital stay were shorter in LAC. There was no conversion in LAC and no significant difference in the postoperative complications. Regarding oncologic long-term outcomes, there were no significant differences between OC and LAC. Laparoscopic resection of Transverse Colon cancer at splenic flexure resulted in acceptable short-term and oncologic long-term outcomes. Once technical tips acquired, laparoscopic resection of Transverse Colon cancer at splenic flexure could be feasible as minimally invasive surgery.
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an internal hernia projecting through a mesenteric defect following laparoscopic assisted partial resection of the Transverse Colon to the lesser omental cleft report of a case
Surgery Today, 2013Co-Authors: Shinsuke Masubuchi, Masashi Yamamoto, Junji Okuda, Keitarou Tanaka, Keisaku Kondo, Keiko Asai, Hajime Kayano, Kazuhisa UchiyamaAbstract:We herein report a case of an internal hernia projecting through a mesenteric defect following laparoscopic-assisted colectomy to the lesser omental cleft in a 61-year-old female. We performed laparoscopic-assisted partial resection of the Transverse Colon to treat Transverse Colon cancer. Three years and 6 months after the operation, the patient developed a bowel obstruction requiring surgical intervention. When we observed the intraperitoneal space under laparoscopy, we determined that the small intestine had passed into the bursa omentalis through the mesenteric defect. Additionally, an abnormal opening of the lesser omentum was present with a portion of the small intestine escaping into the space inferior to the liver. We performed reintegration of the escaped bowel and closed the mesenteric defect laparoscopically. This is the first case of an internal hernia projecting through a mesenteric defect following laparoscopic-assisted colectomy that we have experienced out of more than 2400 cases. Further research is needed to identify the patients who would benefit from the closure of mesenteric defects during laparoscopic-assisted colectomy.
Satoshi Suzuki - One of the best experts on this subject based on the ideXlab platform.
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optimal surgery for mid Transverse Colon cancer laparoscopic extended right hemicolectomy versus laparoscopic Transverse colectomy
World Journal of Surgery, 2018Co-Authors: Takeru Matsuda, Yasuo Sumi, Kimihiro Yamashita, Hiroshi Hasegawa, Masashi Yamamoto, Yoshiko Matsuda, Shingo Kanaji, Taro Oshikiri, Tetsu Nakamura, Satoshi SuzukiAbstract:Although the feasibility and safety of laparoscopic surgery for Transverse Colon cancer have been shown by the recent studies, the optimal laparoscopic approach for mid-Transverse Colon cancer is controversial. We retrospectively analyzed the data of patients with the mid-Transverse Colon cancer at our institutions between January 2007 and April 2017. Thirty-eight and 34 patients who received extended right hemicolectomy and Transverse colectomy, respectively, were enrolled. There were no significant differences in operating time, blood loss, and hospital stay between the two groups. Postoperative complications developed in 10 of 34 patients (29.4%; wound infection: 2 cases, anastomotic leakage: 2 cases, bowel obstruction: 1 case, incisional hernia: 2 cases, others: 3 cases) for the Transverse colectomy group and in 4 of 38 patients (10.5%; wound infection: 1 case, anastomotic leakage: 0 case, bowel obstruction: 2 cases, incisional hernia: 0 case, others: 1 case) for the extended right hemicolectomy group (P = 0.014). Although the median number of harvested #221 and #222 LNs was similar between the two groups (6 vs. 8, P = 0.710, and 3 vs. 2, P = 0.256, respectively), that of #223 was significantly larger in extended right hemicolectomy than in Transverse colectomy (3 vs. 1, P = 0.038). The 5-year disease-free and overall survival rates were 92.4 and 90.3% for the extended right hemicolectomy group, and 95.7 and 79.6% for the Transverse colectomy group (P = 0.593 and P = 0.638, respectively). Laparoscopic extended right hemicolectomy and laparoscopic Transverse colectomy offer similar oncological outcomes for mid-Transverse Colon cancer. Laparoscopic extended right hemicolectomy might be associated with fewer postoperative complications.
Osamu Nishizawa - One of the best experts on this subject based on the ideXlab platform.
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continent urinary reservoir formation with Transverse Colon for patients with pelvic irradiation
International Journal of Urology, 2002Co-Authors: Haruaki Kato, Yasuhiko Igawa, Itsuki Komiyama, Osamu NishizawaAbstract:Background: The creation of a continent Transverse Colon pouch for patients who had previously received radiation therapy for cervical cancer was attempted. Methods: Three patients underwent construction of a continent urinary reservoir. Approximately 30 cm of a Transverse Colon segment was isolated for constructing a pouch. A reconfigured Colon segment was used in two cases as a continent valve and the appendix was used in one case. Both ureters were implanted submucosally into the pouch in two patients and a reconfigured Colon was also used to reconstruct a defect of the ureter in one patient. Results: All patients could catheterize the pouch easily via the cutaneous stoma without incontinence. No complications were noted. Conclusions: In the event that a urinary diversion is necessary for a pateint who has previously had radiation therapy, the Transverse Colon pouch can be a useful method to improve the quality of life. In addition, versatility of the reconfigured Colon segment enables the Colon pouch to be adapted to adverse clinical stiuations.
