The Experts below are selected from a list of 3966 Experts worldwide ranked by ideXlab platform
Margaret C Mckinnon - One of the best experts on this subject based on the ideXlab platform.
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the neural correlates of Trauma Related autobiographical Memory in postTraumatic stress disorder a meta analysis
Depression and Anxiety, 2020Co-Authors: Janine Thome, Braeden A Terpou, Margaret C Mckinnon, Ruth A LaniusAbstract:Background Autobiographical Memory (AM) refers to memories of events that are personally relevant and are remembered from one's own past. The AM network is a distributed brain network comprised largely by prefrontal medial and posteromedial cortical brain regions, which together facilitate AM. Autobiographical memories with high arousal and negatively valenced emotional states are thought to be retrieved more readily and re-experienced more vividly. This is critical in the case of Trauma-Related AMs, which are Related to altered phenomenological experiences as well as aberrations to the underlying neural systems in postTraumatic stress disorder (PTSD). Critically, these alterations to the AM network have not been explored recently and have never been analyzed with consideration to the different processes of AM, them being retrieval and re-experiencing. Methods We conducted a series of effect-size signed differential mapping meta-analyses across twenty-eight studies investigating the neural correlates of Trauma-Related AMs in participants with PTSD as compared with controls. Studies included either Trauma-Related scripts or Trauma-Related materials (i.e., sounds, images, pictures) implemented to evoke the recollection of a Trauma-Related Memory. Results The meta-analyses revealed that control and PTSD participants displayed greater common brain activation of prefrontal medial and posteromedial cortices, respectively. Whereby the prefrontal medial cortices are suggested to facilitate retrieval monitoring, the posteromedial cortices are thought to enable the visual imagery processes of AM. Conclusions Taken together, reduced common activation of prefrontal cortices may be interpreted as a bias toward greater re-experiencing, where the more salient elements of the Traumatic Memory are relived as opposed to retrieved in a controlled manner in PTSD.
Janine Thome - One of the best experts on this subject based on the ideXlab platform.
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the neural correlates of Trauma Related autobiographical Memory in postTraumatic stress disorder a meta analysis
Depression and Anxiety, 2020Co-Authors: Janine Thome, Braeden A Terpou, Margaret C Mckinnon, Ruth A LaniusAbstract:Background Autobiographical Memory (AM) refers to memories of events that are personally relevant and are remembered from one's own past. The AM network is a distributed brain network comprised largely by prefrontal medial and posteromedial cortical brain regions, which together facilitate AM. Autobiographical memories with high arousal and negatively valenced emotional states are thought to be retrieved more readily and re-experienced more vividly. This is critical in the case of Trauma-Related AMs, which are Related to altered phenomenological experiences as well as aberrations to the underlying neural systems in postTraumatic stress disorder (PTSD). Critically, these alterations to the AM network have not been explored recently and have never been analyzed with consideration to the different processes of AM, them being retrieval and re-experiencing. Methods We conducted a series of effect-size signed differential mapping meta-analyses across twenty-eight studies investigating the neural correlates of Trauma-Related AMs in participants with PTSD as compared with controls. Studies included either Trauma-Related scripts or Trauma-Related materials (i.e., sounds, images, pictures) implemented to evoke the recollection of a Trauma-Related Memory. Results The meta-analyses revealed that control and PTSD participants displayed greater common brain activation of prefrontal medial and posteromedial cortices, respectively. Whereby the prefrontal medial cortices are suggested to facilitate retrieval monitoring, the posteromedial cortices are thought to enable the visual imagery processes of AM. Conclusions Taken together, reduced common activation of prefrontal cortices may be interpreted as a bias toward greater re-experiencing, where the more salient elements of the Traumatic Memory are relived as opposed to retrieved in a controlled manner in PTSD.
Ruth A Lanius - One of the best experts on this subject based on the ideXlab platform.
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the neural correlates of Trauma Related autobiographical Memory in postTraumatic stress disorder a meta analysis
Depression and Anxiety, 2020Co-Authors: Janine Thome, Braeden A Terpou, Margaret C Mckinnon, Ruth A LaniusAbstract:Background Autobiographical Memory (AM) refers to memories of events that are personally relevant and are remembered from one's own past. The AM network is a distributed brain network comprised largely by prefrontal medial and posteromedial cortical brain regions, which together facilitate AM. Autobiographical memories with high arousal and negatively valenced emotional states are thought to be retrieved more readily and re-experienced more vividly. This is critical in the case of Trauma-Related AMs, which are Related to altered phenomenological experiences as well as aberrations to the underlying neural systems in postTraumatic stress disorder (PTSD). Critically, these alterations to the AM network have not been explored recently and have never been analyzed with consideration to the different processes of AM, them being retrieval and re-experiencing. Methods We conducted a series of effect-size signed differential mapping meta-analyses across twenty-eight studies investigating the neural correlates of Trauma-Related AMs in participants with PTSD as compared with controls. Studies included either Trauma-Related scripts or Trauma-Related materials (i.e., sounds, images, pictures) implemented to evoke the recollection of a Trauma-Related Memory. Results The meta-analyses revealed that control and PTSD participants displayed greater common brain activation of prefrontal medial and posteromedial cortices, respectively. Whereby the prefrontal medial cortices are suggested to facilitate retrieval monitoring, the posteromedial cortices are thought to enable the visual imagery processes of AM. Conclusions Taken together, reduced common activation of prefrontal cortices may be interpreted as a bias toward greater re-experiencing, where the more salient elements of the Traumatic Memory are relived as opposed to retrieved in a controlled manner in PTSD.
Johan Den A Boer - One of the best experts on this subject based on the ideXlab platform.
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psychobiological characteristics of dissociative identity disorder a symptom provocation study
Biological Psychiatry, 2006Co-Authors: A Simone A T Reinders, Ellert R S Nijenhuis, Jacqueline Quak, Jakob Korf, J Haaksma, Anne M J Paans, Antoon T M Willemsen, Johan Den A BoerAbstract:Background Dissociative identity disorder (DID) patients function as two or more identities or dissociative identity states (DIS), categorized as ‘neutral identity states' (NIS) and ‘Traumatic identity states' (TIS). NIS inhibit access to Traumatic memories thereby enabling daily life functioning. TIS have access and responses to these memories. We tested whether these DIS show different psychobiological reactions to Trauma-Related Memory. Methods A symptom provocation paradigm with 11 DID patients was used in a two-by-two factorial design setting. Both NIS and TIS were exposed to a neutral and a Trauma-Related Memory script. Three psychobiological parameters were tested: subjective ratings (emotional and sensori-motor), cardiovascular responses (heart rate, blood pressure, heart rate variability) and regional cerebral blood flow as determined with H 2 15 O positron emission tomography. Results Psychobiological differences were found for the different DIS. Subjective and cardiovascular reactions revealed significant main and interactions effects. Regional cerebral blood flow data revealed different neural networks to be associated with different processing of the neutral and Trauma-Related Memory script by NIS and TIS. Conclusions Patients with DID encompass at least two different DIS. These identities involve different subjective reactions, cardiovascular responses and cerebral activation patterns to a Trauma-Related Memory script.
Braeden A Terpou - One of the best experts on this subject based on the ideXlab platform.
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the neural correlates of Trauma Related autobiographical Memory in postTraumatic stress disorder a meta analysis
Depression and Anxiety, 2020Co-Authors: Janine Thome, Braeden A Terpou, Margaret C Mckinnon, Ruth A LaniusAbstract:Background Autobiographical Memory (AM) refers to memories of events that are personally relevant and are remembered from one's own past. The AM network is a distributed brain network comprised largely by prefrontal medial and posteromedial cortical brain regions, which together facilitate AM. Autobiographical memories with high arousal and negatively valenced emotional states are thought to be retrieved more readily and re-experienced more vividly. This is critical in the case of Trauma-Related AMs, which are Related to altered phenomenological experiences as well as aberrations to the underlying neural systems in postTraumatic stress disorder (PTSD). Critically, these alterations to the AM network have not been explored recently and have never been analyzed with consideration to the different processes of AM, them being retrieval and re-experiencing. Methods We conducted a series of effect-size signed differential mapping meta-analyses across twenty-eight studies investigating the neural correlates of Trauma-Related AMs in participants with PTSD as compared with controls. Studies included either Trauma-Related scripts or Trauma-Related materials (i.e., sounds, images, pictures) implemented to evoke the recollection of a Trauma-Related Memory. Results The meta-analyses revealed that control and PTSD participants displayed greater common brain activation of prefrontal medial and posteromedial cortices, respectively. Whereby the prefrontal medial cortices are suggested to facilitate retrieval monitoring, the posteromedial cortices are thought to enable the visual imagery processes of AM. Conclusions Taken together, reduced common activation of prefrontal cortices may be interpreted as a bias toward greater re-experiencing, where the more salient elements of the Traumatic Memory are relived as opposed to retrieved in a controlled manner in PTSD.
