The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform
Shoji Yahara - One of the best experts on this subject based on the ideXlab platform.
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Determination and Identification of a Specific Marker Compound for Discriminating Shrub Chaste Tree Fruit from Agnus Castus Fruit Based on LC/MS Metabolic Analysis.
Chemical & pharmaceutical bulletin, 2016Co-Authors: Tadahiro Yahagi, Naohiro Oshima, Sayaka Masada, Ryuta Suzuki, Hiroshi Matsufuji, Yutaka Takahashi, Masato Watanabe, Shoji Yahara, Osamu Iida, Nobuo KawaharaAbstract:Shrub Chaste Tree Fruit (SCTF) is defined as the Fruits of Vitex rotundifolia L. f. and V. trifolia L. and has been used as a component of some traditional Japanese medicines (Kampo formulations). Agnus Castus Fruit (ACF) is defined as the dried ripe Fruits of V. agnus-castus L.; it is used in traditional European medicines, but is becoming popular in Japan as both an over-the-counter drug and as an ingredient in health foods for treating premenstrual syndrome (PMS). To ensure the efficacy and safety of both SCTF and ACF products, it is important to precisely authenticate their botanical origins and to clearly distinguish between SCTF and ACF. Therefore, we tried to identify SCTF-specific marker compounds based on LC/MS metabolic analysis. The multivariate analysis of LC/MS data from SCTF and ACF samples furnished candidate marker compounds of SCTF. An SCTF-specific marker was isolated from SCTF crude drugs and identified as 3-O-trans-feruloyl tormentic acid on the basis of spectroscopic data from NMR and MS. Since avoiding contamination from closely related species is a significant requirement for pharmaceuticals of natural origin, this information will be valuable for the quality control of both SCTF and ACF products from the viewpoint of regulatory science.
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Identification of New Diterpenes as Putative Marker Compounds Distinguishing Agnus Castus Fruit (Chaste Tree) from Shrub Chaste Tree Fruit (Viticis Fructus)
Planta medica, 2016Co-Authors: Naohiro Oshima, Sayaka Masada, Ryuta Suzuki, Kanae Yagi, Hiroshi Matsufuji, Emi Suenaga, Yutaka Takahashi, Tadahiro Yahagi, Masato Watanabe, Shoji YaharaAbstract:Agnus Castus Fruit is defined in the European Pharmacopoeia as the dried ripe Fruit of Vitex agnus-castus. In Europe it is used as a medicine targeting premenstrual syndrome and climacteric disorder. In Japan, Agnus Castus Fruit is becoming popular as a raw material for over-the-counter drugs and health food products, though its congenic species, Vitex rotundifolia and Vitex trifolia, have been used as Shrub Chaste Tree Fruit in traditional medicines. Therefore, it is important to discriminate these Vitex plants from the viewpoint of regulatory science. Here we tried to identify putative marker compounds that distinguish between Agnus Castus Fruit and Shrub Chaste Tree Fruit. We analyzed extracts of each crude drug by liquid chromatography-mass spectrometry, and performed differential analysis by comparison of each chromatogram to find one or more peaks characteristic of Agnus Castus Fruit. A peak was isolated and identified as an equilibrium mixture of new compounds named chastol (1) and epichastol (1a). The planar structures of 1 and 1a were determined spectroscopically. Their relative configurations were revealed by nuclear Overhauser effect spectroscopy and differential nuclear Overhauser effect-NMR data. Since avoiding contamination from closely related species is needed for the quality control of natural pharmaceuticals, this information will be valuable to establish a method for the quality control of both, Agnus Castus Fruit and Shrub Chaste Tree Fruit products.
David Granatstein - One of the best experts on this subject based on the ideXlab platform.
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Presentation: Recent trends in certified organic Tree Fruit, Washington State 2014
2015Co-Authors: Elizabeth Kirby, David GranatsteinAbstract:Kirby, E. and D. Granatstein. 2015. Recent trends in certified organic Tree Fruit: Washington State 2014. CSANR Organic Trends Series. 76 pp.
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Presentation: Organic Tree Fruit trends, 2013
2014Co-Authors: Elizabeth Kirby, David GranatsteinAbstract:Kirby, E. and D. Granatstein. 2014. Organic Tree Fruit trends, 2013. http://csanr.wsu.edu/wp-content/uploads/2014/01/WA_OrgTreeFruit_2013.pdf.
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Estimated Washington Organic Tree Fruit Acreage and Price Trends – 2005
2013Co-Authors: David Granatstein, Elizabeth Kirby, Chris FeiseAbstract:Statistics on organic Tree Fruit production in Washington State have been compiled by WSU-CSANR since 1998, with the goal of producing annual updates to provide growers and the industry with current information. The report provides a best estimate of certified organic Tree Fruit and includes data from acreage certified by the Washington State Department of Agriculture (WSDA) Organic Food program, Oregon Tilth Certification Organization (OTCO) and Quality Assurance International (QAI). Data cover the period of calendar year 2005. Information for exempt producers (less than $5000 gross sales) who chose not to be certified is not included. Transitional acreage is included. However, growers are not required to register transitional acreage (since 2002) and the numbers presented here are likely less than the actual total, which is unknown. Price trend information is based on data from the Washington Grower’s Clearing House Association. Organic Tree Fruit production is primarily based in the central, irrigated areas of Washington State. Apple acreage is dominant (75%), with reports of substantial acres in transition due to increased market demand. Washington leads the nation for organic apple production. Grant and Yakima counties produced 45 % of WA organic apples in 2005; Okanogan county production has declined by around half since 2000. Production of organic apples and pears expanded rapidly in the late 1990’s in response t
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Presentation: Recent Trends in Certified Organic Tree Fruit, Washington State 2012
2013Co-Authors: Elizabeth Kirby, David GranatsteinAbstract:Kirby, E.M., and D. Granatstein. 2013. Recent Trends in Certified Organic Tree Fruit. WSU CSANR. http://www.tfrec.wsu.edu/pdfs/P2767.pdf.
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Status of organic Tree Fruit in Washington state
2012Co-Authors: Elizabeth Kirby, David GranatsteinAbstract:Summary The certified acres of organic apples and cherries in Washington State expanded by over 60% in 2008 at the same time that growth of organic food sales slowed to the lowest level (4%) in 20 years due to economic stress in the US. The impact of these changes on prices will be closely followed for this marketing season. An additional 4,000 acres of organic apples are in transition, along with expansion for various soft Fruit crops. Organic apples now represent about 8% of all apple acres in the state. Dr. Des O'Rourke recently modeled the organic apple sector and estimated that organic apple price premiums would approach zero when organic comprised 12% of the state apple acres. More attention will need to be paid to matching growth of organic Fruit production with growth in demand to retain premium prices. In addition, economic studies are needed to understand the cost structure for organic production and where research could contribute to lower expenses.
Naohiro Oshima - One of the best experts on this subject based on the ideXlab platform.
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Determination and Identification of a Specific Marker Compound for Discriminating Shrub Chaste Tree Fruit from Agnus Castus Fruit Based on LC/MS Metabolic Analysis.
Chemical & pharmaceutical bulletin, 2016Co-Authors: Tadahiro Yahagi, Naohiro Oshima, Sayaka Masada, Ryuta Suzuki, Hiroshi Matsufuji, Yutaka Takahashi, Masato Watanabe, Shoji Yahara, Osamu Iida, Nobuo KawaharaAbstract:Shrub Chaste Tree Fruit (SCTF) is defined as the Fruits of Vitex rotundifolia L. f. and V. trifolia L. and has been used as a component of some traditional Japanese medicines (Kampo formulations). Agnus Castus Fruit (ACF) is defined as the dried ripe Fruits of V. agnus-castus L.; it is used in traditional European medicines, but is becoming popular in Japan as both an over-the-counter drug and as an ingredient in health foods for treating premenstrual syndrome (PMS). To ensure the efficacy and safety of both SCTF and ACF products, it is important to precisely authenticate their botanical origins and to clearly distinguish between SCTF and ACF. Therefore, we tried to identify SCTF-specific marker compounds based on LC/MS metabolic analysis. The multivariate analysis of LC/MS data from SCTF and ACF samples furnished candidate marker compounds of SCTF. An SCTF-specific marker was isolated from SCTF crude drugs and identified as 3-O-trans-feruloyl tormentic acid on the basis of spectroscopic data from NMR and MS. Since avoiding contamination from closely related species is a significant requirement for pharmaceuticals of natural origin, this information will be valuable for the quality control of both SCTF and ACF products from the viewpoint of regulatory science.
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Identification of New Diterpenes as Putative Marker Compounds Distinguishing Agnus Castus Fruit (Chaste Tree) from Shrub Chaste Tree Fruit (Viticis Fructus)
Planta medica, 2016Co-Authors: Naohiro Oshima, Sayaka Masada, Ryuta Suzuki, Kanae Yagi, Hiroshi Matsufuji, Emi Suenaga, Yutaka Takahashi, Tadahiro Yahagi, Masato Watanabe, Shoji YaharaAbstract:Agnus Castus Fruit is defined in the European Pharmacopoeia as the dried ripe Fruit of Vitex agnus-castus. In Europe it is used as a medicine targeting premenstrual syndrome and climacteric disorder. In Japan, Agnus Castus Fruit is becoming popular as a raw material for over-the-counter drugs and health food products, though its congenic species, Vitex rotundifolia and Vitex trifolia, have been used as Shrub Chaste Tree Fruit in traditional medicines. Therefore, it is important to discriminate these Vitex plants from the viewpoint of regulatory science. Here we tried to identify putative marker compounds that distinguish between Agnus Castus Fruit and Shrub Chaste Tree Fruit. We analyzed extracts of each crude drug by liquid chromatography-mass spectrometry, and performed differential analysis by comparison of each chromatogram to find one or more peaks characteristic of Agnus Castus Fruit. A peak was isolated and identified as an equilibrium mixture of new compounds named chastol (1) and epichastol (1a). The planar structures of 1 and 1a were determined spectroscopically. Their relative configurations were revealed by nuclear Overhauser effect spectroscopy and differential nuclear Overhauser effect-NMR data. Since avoiding contamination from closely related species is needed for the quality control of natural pharmaceuticals, this information will be valuable to establish a method for the quality control of both, Agnus Castus Fruit and Shrub Chaste Tree Fruit products.
Paul D Sampson - One of the best experts on this subject based on the ideXlab platform.
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associations between heat exposure vigilance and balance performance in summer Tree Fruit harvesters
Applied Ergonomics, 2018Co-Authors: June T Spector, Jennifer Krenz, Miriam Calkins, Dawn Ryan, Jose Carmona, Mengjie Pan, Anna Zemke, Paul D SampsonAbstract:Abstract Background We sought to evaluate potential mediators of the relationship between heat exposure and traumatic injuries in outdoor agricultural workers. Methods Linear mixed models were used to estimate associations between maximum work-shift Wet Bulb Globe Temperature (WBGT max ) and post-shift vigilance (reaction time) and postural sway (total path length) in a cross-sectional sample of 46 Washington State Tree Fruit harvesters in August–September 2015. Results The mean (SD) WBGT max was 27.4 (3.2)°C in August and 21.2 (2.0)°C in September. The mean pre-work-shift participant urine specific gravity indicated minimal dehydration. Twenty-four percent of participants exhibited possible excessive sleepiness. There was no association between WBGT max and post-shift reaction time or total path length. Conclusions Heat exposure was not associated with impaired vigilance or balance in this study, in which the overall mean (SD) WBGT max was 25.9 (4.2)°C. However, the study identified opportunities to ensure adequate pre-work-shift hydration and to optimize sleep and work-shift timing in order to reduce occupational injury and heat-related illness risk.
Elizabeth Kirby - One of the best experts on this subject based on the ideXlab platform.
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Presentation: Recent trends in certified organic Tree Fruit, Washington State 2014
2015Co-Authors: Elizabeth Kirby, David GranatsteinAbstract:Kirby, E. and D. Granatstein. 2015. Recent trends in certified organic Tree Fruit: Washington State 2014. CSANR Organic Trends Series. 76 pp.
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Presentation: Organic Tree Fruit trends, 2013
2014Co-Authors: Elizabeth Kirby, David GranatsteinAbstract:Kirby, E. and D. Granatstein. 2014. Organic Tree Fruit trends, 2013. http://csanr.wsu.edu/wp-content/uploads/2014/01/WA_OrgTreeFruit_2013.pdf.
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Estimated Washington Organic Tree Fruit Acreage and Price Trends – 2005
2013Co-Authors: David Granatstein, Elizabeth Kirby, Chris FeiseAbstract:Statistics on organic Tree Fruit production in Washington State have been compiled by WSU-CSANR since 1998, with the goal of producing annual updates to provide growers and the industry with current information. The report provides a best estimate of certified organic Tree Fruit and includes data from acreage certified by the Washington State Department of Agriculture (WSDA) Organic Food program, Oregon Tilth Certification Organization (OTCO) and Quality Assurance International (QAI). Data cover the period of calendar year 2005. Information for exempt producers (less than $5000 gross sales) who chose not to be certified is not included. Transitional acreage is included. However, growers are not required to register transitional acreage (since 2002) and the numbers presented here are likely less than the actual total, which is unknown. Price trend information is based on data from the Washington Grower’s Clearing House Association. Organic Tree Fruit production is primarily based in the central, irrigated areas of Washington State. Apple acreage is dominant (75%), with reports of substantial acres in transition due to increased market demand. Washington leads the nation for organic apple production. Grant and Yakima counties produced 45 % of WA organic apples in 2005; Okanogan county production has declined by around half since 2000. Production of organic apples and pears expanded rapidly in the late 1990’s in response t
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Presentation: Recent Trends in Certified Organic Tree Fruit, Washington State 2012
2013Co-Authors: Elizabeth Kirby, David GranatsteinAbstract:Kirby, E.M., and D. Granatstein. 2013. Recent Trends in Certified Organic Tree Fruit. WSU CSANR. http://www.tfrec.wsu.edu/pdfs/P2767.pdf.
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Status of organic Tree Fruit in Washington state
2012Co-Authors: Elizabeth Kirby, David GranatsteinAbstract:Summary The certified acres of organic apples and cherries in Washington State expanded by over 60% in 2008 at the same time that growth of organic food sales slowed to the lowest level (4%) in 20 years due to economic stress in the US. The impact of these changes on prices will be closely followed for this marketing season. An additional 4,000 acres of organic apples are in transition, along with expansion for various soft Fruit crops. Organic apples now represent about 8% of all apple acres in the state. Dr. Des O'Rourke recently modeled the organic apple sector and estimated that organic apple price premiums would approach zero when organic comprised 12% of the state apple acres. More attention will need to be paid to matching growth of organic Fruit production with growth in demand to retain premium prices. In addition, economic studies are needed to understand the cost structure for organic production and where research could contribute to lower expenses.
