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A Cholarajan - One of the best experts on this subject based on the ideXlab platform.
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Tylophora asthmatica L. Prevents Lipid Peroxidation in Acetaminophen Induced Hepato Toxicity in Rats
Asian Journal of Research in Pharmaceutical Science, 2020Co-Authors: R Malathi, S. Ahamed John, A CholarajanAbstract:Methanolic extract of Tylophora asthmatica leaves were prepared and tested for its antilipidperoxidation effect against acetaminophen induced hepato toxicity in rats. Alteration in the levels of lipid peroxide, iron, ferritin, total cholesterol, total lipid and phospholipids were tested in both experiment and control group of rats. Acetaminophen [1gm/kg] has showed a significant increase [p
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antioxidant activity of extract from the leaves of Tylophora asthmatica
Journal of Microbiology and Antimicrobials, 2012Co-Authors: R Malathi, Ahamed S John, A CholarajanAbstract:Extract from the leaves of Tylophora asthmatica were investigated for antioxidant activity. The methanolic extract of T. asthmatica had a 2, 2 diphenyl 1-1-picryl hydiazyl (DPPH) scavenging activity of 84.6% at 250 μg/ml and a reductive potential of 0.77% at 100 μg/ml. These values were comparable with those of Gallic acid, 91.4% at 250 μg/ml and ascorbic acid, 0.79% at 60 μg/ml as standards for DPPH scavenging activity and reductive potential, respectively. These findings suggest that the rich phytochemical content of T. asthmatica and its good antioxidant activity may be responsible for its popular and wide traditional use. The experiment was carried out with the leaves of the selected medicinal plants. The results are discussed with the available literature. Key words: Tylophora asthmatica, antioxidant activity, reductive potential, 2, 2 diphenyl 1-1-picryl hydiazyl (DPPH).
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Tylophora asthmatica l prevents lipid peroxidation in acetaminophen induced hepato toxicity in rats
Asian Journal of Research in Pharmaceutical Science, 2011Co-Authors: R Malathi, Ahamed S John, A CholarajanAbstract:Methanolic extract of Tylophora asthmatica leaves were prepared and tested for its antilipidperoxidation effect against acetaminophen induced hepato toxicity in rats. Alteration in the levels of lipid peroxide, iron, ferritin, total cholesterol, total lipid and phospholipids were tested in both experiment and control group of rats. Acetaminophen [1gm/kg] has showed a significant increase [p<0.05] in experimental rats except the level of phospholipids, which showed a significant decrease [p<0.05] compared to control rats. Treatment with methanolic extract of Tylophora asthmatica leaves [200mg/kg] has brought back the altered levels of this parameter to the near normal levels in the dose dependent manner.
R Malathi - One of the best experts on this subject based on the ideXlab platform.
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Tylophora asthmatica L. Prevents Lipid Peroxidation in Acetaminophen Induced Hepato Toxicity in Rats
Asian Journal of Research in Pharmaceutical Science, 2020Co-Authors: R Malathi, S. Ahamed John, A CholarajanAbstract:Methanolic extract of Tylophora asthmatica leaves were prepared and tested for its antilipidperoxidation effect against acetaminophen induced hepato toxicity in rats. Alteration in the levels of lipid peroxide, iron, ferritin, total cholesterol, total lipid and phospholipids were tested in both experiment and control group of rats. Acetaminophen [1gm/kg] has showed a significant increase [p
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antioxidant activity of extract from the leaves of Tylophora asthmatica
Journal of Microbiology and Antimicrobials, 2012Co-Authors: R Malathi, Ahamed S John, A CholarajanAbstract:Extract from the leaves of Tylophora asthmatica were investigated for antioxidant activity. The methanolic extract of T. asthmatica had a 2, 2 diphenyl 1-1-picryl hydiazyl (DPPH) scavenging activity of 84.6% at 250 μg/ml and a reductive potential of 0.77% at 100 μg/ml. These values were comparable with those of Gallic acid, 91.4% at 250 μg/ml and ascorbic acid, 0.79% at 60 μg/ml as standards for DPPH scavenging activity and reductive potential, respectively. These findings suggest that the rich phytochemical content of T. asthmatica and its good antioxidant activity may be responsible for its popular and wide traditional use. The experiment was carried out with the leaves of the selected medicinal plants. The results are discussed with the available literature. Key words: Tylophora asthmatica, antioxidant activity, reductive potential, 2, 2 diphenyl 1-1-picryl hydiazyl (DPPH).
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Tylophora asthmatica l prevents lipid peroxidation in acetaminophen induced hepato toxicity in rats
Asian Journal of Research in Pharmaceutical Science, 2011Co-Authors: R Malathi, Ahamed S John, A CholarajanAbstract:Methanolic extract of Tylophora asthmatica leaves were prepared and tested for its antilipidperoxidation effect against acetaminophen induced hepato toxicity in rats. Alteration in the levels of lipid peroxide, iron, ferritin, total cholesterol, total lipid and phospholipids were tested in both experiment and control group of rats. Acetaminophen [1gm/kg] has showed a significant increase [p<0.05] in experimental rats except the level of phospholipids, which showed a significant decrease [p<0.05] compared to control rats. Treatment with methanolic extract of Tylophora asthmatica leaves [200mg/kg] has brought back the altered levels of this parameter to the near normal levels in the dose dependent manner.
Jaime A. Teixeira Da Silva - One of the best experts on this subject based on the ideXlab platform.
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Micropropagation and genetic transformation of Tylophora indica (Burm. f.) Merr.: a review
Plant Cell Reports, 2016Co-Authors: Jaime A. Teixeira Da SilvaAbstract:Key message This review provides an in-depth and comprehensive overview of the in vitro culture of Tylophora species, which have medicinal properties. Abstract Tylophora indica (Burm. f.) Merr. is a climbing perennial vine with medicinal properties. The tissue culture and genetic transformation of T. indica , which has been extensively studied, is reviewed. Micropropagation using nodal explants has been reported in 25 % of all publications. Leaf explants from field-grown plants has been the explant of choice of independent research groups, which reported direct and callus-mediated organogenesis as well as callus-mediated somatic embryogenesis. Protoplast-mediated regeneration and callus-mediated shoot organogenesis has also been reported from stem explants, and to a lesser degree from root explants of micropropagated plants in vitro. Recent studies that used HPLC confirmed the potential of micropropagated plants to synthesize the major T. indica alkaloid tylophorine prior to and after transfer to field conditions. The genetic integrity of callus-regenerated plants was confirmed by RAPD in a few reports. Tissue culture is an essential base for genetic transformation studies. Hairy roots and transgenic T. indica plants have been shown to accumulate tylophorine suggesting that in vitro biology and transgenic methods are viable ways of clonally producing valuable germplasm and mass producing compounds of commercial value. Further studies that investigate the factors affecting the biosynthesis of Tylophora alkaloids and other secondary metabolites need to be conducted using non-transformed as well as transformed cell and organ cultures.
Sigrid Liedeschumann - One of the best experts on this subject based on the ideXlab platform.
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vincetoxicum apocynaceae asclepiadoideae expanded to include Tylophora and allies
Phytotaxa, 2018Co-Authors: Sigrid Liedeschumann, Ulrich MeveAbstract:All 301 names in Tylophora and the small genera in Asclepiadeae-Tylophorinae now considered synonymous with Vincetoxicum , namely Amblyoglossum , Belostemma , Biondia , Blyttia , Diplostigma , Goydera , Hoyopsis , Hybanthera , Iphisia , Ischnostemma , Merrillanthus , Microstephanus , Nanostelma , Neohenrya , Oncostemma , Pentabothra , Pentastelma , Pleurostelma , Podostelma , Pycnostelma , Rhyncharrhena , Sphaerocodon , Spirella , Tylophoropsis and Vincetoxicopsis , are listed. A total of 107 new combinations are made (104 in Vincetoxicum , one in Dregea , one in Marsdenia , and one in Lygisma ), 25 nomina nova have been coined, 141 typifications are undertaken and 10 new synonyms are proposed.
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cynanchum rhodostegiella vincetoxicum Tylophora asclepiadaceae new considerations on an old problem
Taxon, 1996Co-Authors: Sigrid LiedeschumannAbstract:On the basis of morphological and chemical data, the genus Vincetoxicum is recognized as separate from Cynanchum. Tylophora is identified as the closest relative of Vincetoxicum. In consequence, eleven new combinations in Vincetoxicum are proposed. The C. auriculatum group is recognized as C. sect. Rhodostegiella. Tylophoropsis must be included in Tylophora, which results in one new combination.
Masayuki Maki - One of the best experts on this subject based on the ideXlab platform.
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morphological aspects and phylogenetic analyses of pollination systems in the Tylophora vincetoxicum complex apocynaceae asclepiadoideae in japan
Biological Journal of The Linnean Society, 2008Co-Authors: Tadashi Yamashiro, Asuka Yamashiro, Jun Yokoyama, Masayuki MakiAbstract:Pollinators of two Cynanchum, five Tylophora, and 16 Vincetoxicum species were observed in 26 populations in Japan. The following pollination systems were observed in 18 species: moth pollination, generalized insect pollination, wasp pollination, dipteran pollination, both dipteran and moth pollination, and autogamy. Principal component analysis based on 13 floral characters indicated that the size of the pollinator tended to increase with sizes of all characters measured. Furthermore, species that have developed interstaminal parts of the corona and concealed stigmatic chambers tend to be pollinated by long-tongued insects. The phylogenetic distribution of pollinator types showed that species belonging to Clade I are pollinated exclusively by Diptera, whereas those of Clade II are pollinated by four insect orders. The most prominent pollinator transition in the Tylophora–Vincetoxicum complex is dipteran to moth pollination. The most common morphological change of the plants from dipteran pollination to moth pollination, or vice versa, is modification of the corolla. In the Tylophora–Vincetoxicum complex, pollination mode shifts are generally accompanied by modifications of the corona and the structure of gynostegium. One hypothesis for the rapid radiation observed in Clade II is that a widely distributed species may have partitioned its distribution in the relatively near past and adapted to various environments, in which the dominant pollinators were different, and that the local races may then have diverged from each other after they were isolated. © 2008 The Linnean Society of London, Biological Journal of the Linnean Society, 2008, 93, 325–341.
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Morphological aspects and phylogenetic analyses of pollination systems in the Tylophora–Vincetoxicum complex (Apocynaceae-Asclepiadoideae) in Japan
Biological Journal of The Linnean Society, 2008Co-Authors: Tadashi Yamashiro, Asuka Yamashiro, Jun Yokoyama, Masayuki MakiAbstract:Pollinators of two Cynanchum, five Tylophora, and 16 Vincetoxicum species were observed in 26 populations in Japan. The following pollination systems were observed in 18 species: moth pollination, generalized insect pollination, wasp pollination, dipteran pollination, both dipteran and moth pollination, and autogamy. Principal component analysis based on 13 floral characters indicated that the size of the pollinator tended to increase with sizes of all characters measured. Furthermore, species that have developed interstaminal parts of the corona and concealed stigmatic chambers tend to be pollinated by long-tongued insects. The phylogenetic distribution of pollinator types showed that species belonging to Clade I are pollinated exclusively by Diptera, whereas those of Clade II are pollinated by four insect orders. The most prominent pollinator transition in the Tylophora–Vincetoxicum complex is dipteran to moth pollination. The most common morphological change of the plants from dipteran pollination to moth pollination, or vice versa, is modification of the corolla. In the Tylophora–Vincetoxicum complex, pollination mode shifts are generally accompanied by modifications of the corona and the structure of gynostegium. One hypothesis for the rapid radiation observed in Clade II is that a widely distributed species may have partitioned its distribution in the relatively near past and adapted to various environments, in which the dominant pollinators were different, and that the local races may then have diverged from each other after they were isolated. © 2008 The Linnean Society of London, Biological Journal of the Linnean Society, 2008, 93, 325–341.
