The Experts below are selected from a list of 1017 Experts worldwide ranked by ideXlab platform
Ya-hui Chuang - One of the best experts on this subject based on the ideXlab platform.
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Early congenital syphilis and erythema multiforme–like bullous targetoid lesions in a 1-day-old newborn: Detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction
Journal of the American Academy of Dermatology, 2006Co-Authors: Chi-neu Tsai, Wen-rou Wong, Hong-shang Hong, Ya-hui ChuangAbstract:A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections Staining with Warthin-Starry Stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
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Early congenital syphilis and erythema multiforme-like bullous targetoid lesions in a 1-day-old newborn: detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction.
Journal of the American Academy of Dermatology, 2006Co-Authors: Chi-neu Tsai, Wen-rou Wong, Hong-shang Hong, Ya-hui ChuangAbstract:A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections Staining with Warthin-Starry Stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
Chi-neu Tsai - One of the best experts on this subject based on the ideXlab platform.
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Early congenital syphilis and erythema multiforme–like bullous targetoid lesions in a 1-day-old newborn: Detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction
Journal of the American Academy of Dermatology, 2006Co-Authors: Chi-neu Tsai, Wen-rou Wong, Hong-shang Hong, Ya-hui ChuangAbstract:A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections Staining with Warthin-Starry Stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
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Early congenital syphilis and erythema multiforme-like bullous targetoid lesions in a 1-day-old newborn: detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction.
Journal of the American Academy of Dermatology, 2006Co-Authors: Chi-neu Tsai, Wen-rou Wong, Hong-shang Hong, Ya-hui ChuangAbstract:A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections Staining with Warthin-Starry Stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
Hong-shang Hong - One of the best experts on this subject based on the ideXlab platform.
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Early congenital syphilis and erythema multiforme–like bullous targetoid lesions in a 1-day-old newborn: Detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction
Journal of the American Academy of Dermatology, 2006Co-Authors: Chi-neu Tsai, Wen-rou Wong, Hong-shang Hong, Ya-hui ChuangAbstract:A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections Staining with Warthin-Starry Stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
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Early congenital syphilis and erythema multiforme-like bullous targetoid lesions in a 1-day-old newborn: detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction.
Journal of the American Academy of Dermatology, 2006Co-Authors: Chi-neu Tsai, Wen-rou Wong, Hong-shang Hong, Ya-hui ChuangAbstract:A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections Staining with Warthin-Starry Stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
Wen-rou Wong - One of the best experts on this subject based on the ideXlab platform.
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Early congenital syphilis and erythema multiforme–like bullous targetoid lesions in a 1-day-old newborn: Detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction
Journal of the American Academy of Dermatology, 2006Co-Authors: Chi-neu Tsai, Wen-rou Wong, Hong-shang Hong, Ya-hui ChuangAbstract:A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections Staining with Warthin-Starry Stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
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Early congenital syphilis and erythema multiforme-like bullous targetoid lesions in a 1-day-old newborn: detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction.
Journal of the American Academy of Dermatology, 2006Co-Authors: Chi-neu Tsai, Wen-rou Wong, Hong-shang Hong, Ya-hui ChuangAbstract:A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections Staining with Warthin-Starry Stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
Lorenzo Cerroni - One of the best experts on this subject based on the ideXlab platform.
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treponema pallidum distribution patterns in mucocutaneous lesions of primary and secondary syphilis an immunohistochemical and ultrastructural study
Human Pathology, 2009Co-Authors: Gemma Martinezquerra, Jose Luis Rodriguezperalto, Ale Fernandezcasado, Didac Arco, Anna Jucgla, Nuria Juanpererodero, Josep Maria Manresa, Luis Soares De Almeida, Heinz Kutzne, Lorenzo CerroniAbstract:To study the different patterns of Treponema pallidum distribution in primary and secondary syphilis, 34 biopsy specimens of 8 patients with primary and 26 with secondary syphilis were assessed. Histopathological features, silver Stain, and immunohistochemical T pallidum polyclonal antibody expression were investigated. The number and distribution of spirochetes were evaluated, and ultrastructural studies were performed. Spirochetes were identified with Warthin-Starry Stain in 17 specimens (4/8 primary and 13/26 secondary syphilis), whereas immunohistochemical analysis disclosed spirochetes in 29 (8/8 primary and 21/26 secondary syphilis). In secondary syphilis, an epitheliotropic pattern characterized by abundant spirochetes in the lower mucosa/epidermis in an intercellular distribution was observed. In contrast, primary syphilis exhibited a mixed epitheliotropic and vasculotropic pattern further manifested by treponemes surrounding the vascular walls. These differences were statistically significant. Ultrastructural examination confirmed these results. Immunohistochemistry shows greater sensitivity when compared with Warthin-Starry Staining. The immunohistochemical pattern of T pallidum distribution may permit the diagnostic differentiation of primary from secondary syphilis.
