The Experts below are selected from a list of 273 Experts worldwide ranked by ideXlab platform
Amir Hossein Jafarian - One of the best experts on this subject based on the ideXlab platform.
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subcutaneous connective tissue reaction to a new nano Zinc Oxide Eugenol sealer in rat model
iranian endodontic journal, 2017Co-Authors: Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amir Hossein JafarianAbstract:Introduction: The aim of this animal study was to evaluate the histological response of the new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). Methods and Materials: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues.Samples were evaluated for the presence of inflammatory cell (mononuclear cell), vascular changes, fibrous tissue formation and present of giant cell. Comparisons between groups and time-periods were performed using the Kruskal-Wallis and Mann-Whitney U non-parametric tests. The level of significance was set at 0.05. Results: No significant difference was observed in tissue reactions and biocompatibility pattern of three sealers during 3 experimental periods ( P <0.05). In all groups the tissue behavior showed tendency to decrease the irritation effect over time. Conclusion: The new nano Zinc-Oxide Eugenol sealer has histocompatibility properties comparable to conventional commercial sealers. Keywords: Biocompatibility; Nanoparticle; Tissue Reaction; Zinc-Oxide Eugenol
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Subcutaneous Connective Tissue Reaction to a New Nano Zinc-Oxide Eugenol Sealer in Rat Model
iranian endodontic journal, 2017Co-Authors: Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amir Hossein JafarianAbstract:Introduction: The aim of this animal study was to evaluate the histological response of the new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). Methods and Materials: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues.Samples were evaluated for the presence of inflammatory cell (mononuclear cell), vascular changes, fibrous tissue formation and present of giant cell. Comparisons between groups and time-periods were performed using the Kruskal-Wallis and Mann-Whitney U non-parametric tests. The level of significance was set at 0.05. Results: No significant difference was observed in tissue reactions and biocompatibility pattern of three sealers during 3 experimental periods ( P
Jia-horng Lin - One of the best experts on this subject based on the ideXlab platform.
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Mechanical Property Evaluation of Fiber-Reinforced and Fabric-Reinforced Zinc Oxide-Eugenol Temporary Filling Materials
Journal of Engineered Fibers and Fabrics, 2014Co-Authors: Jia-horng LinAbstract:Zinc Oxide-Eugenol (ZOE) is usually applied clinically as dental filling material for thermal insulation and temporary restoration. The objective of this study was to use ZOE as a composite matrix and low melting-point polyester fibers or fabrics as reinforcement. The added fibers or fabrics increased the composite materials’ compressive load by 250 N and 290 N, respectively. Fiber length and thermal-drying temperatures had no significant influence on setting time (p>0.05), but the degree of solubility of the filling material had statistical significance (p
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mechanical property evaluation of fiber reinforced and fabric reinforced Zinc Oxide Eugenol temporary filling materials
Journal of Engineered Fibers and Fabrics, 2014Co-Authors: Jia-horng LinAbstract:Zinc Oxide-Eugenol (ZOE) is usually applied clinically as dental filling material for thermal insulation and temporary restoration. The objective of this study was to use ZOE as a composite matrix and low melting-point polyester fibers or fabrics as reinforcement. The added fibers or fabrics increased the composite materials’ compressive load by 250 N and 290 N, respectively. Fiber length and thermal-drying temperatures had no significant influence on setting time (p>0.05), but the degree of solubility of the filling material had statistical significance (p<0.05). Only the compressive load results were raised at the end of the curve. The optimum compressive load results, 290 N and 331 N, were observed in the 10 mm PET fiber processed at 130 °C. With its excellent compressive load, this composite material has the ability to sustain a bigger bite force; thus, the fiber-reinforced or fabric-reinforced composite materials are feasible for temporary clinical dental treatment.
Salma Omidi - One of the best experts on this subject based on the ideXlab platform.
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subcutaneous connective tissue reaction to a new nano Zinc Oxide Eugenol sealer in rat model
iranian endodontic journal, 2017Co-Authors: Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amir Hossein JafarianAbstract:Introduction: The aim of this animal study was to evaluate the histological response of the new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). Methods and Materials: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues.Samples were evaluated for the presence of inflammatory cell (mononuclear cell), vascular changes, fibrous tissue formation and present of giant cell. Comparisons between groups and time-periods were performed using the Kruskal-Wallis and Mann-Whitney U non-parametric tests. The level of significance was set at 0.05. Results: No significant difference was observed in tissue reactions and biocompatibility pattern of three sealers during 3 experimental periods ( P <0.05). In all groups the tissue behavior showed tendency to decrease the irritation effect over time. Conclusion: The new nano Zinc-Oxide Eugenol sealer has histocompatibility properties comparable to conventional commercial sealers. Keywords: Biocompatibility; Nanoparticle; Tissue Reaction; Zinc-Oxide Eugenol
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Subcutaneous Connective Tissue Reaction to a New Nano Zinc-Oxide Eugenol Sealer in Rat Model
iranian endodontic journal, 2017Co-Authors: Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amir Hossein JafarianAbstract:Introduction: The aim of this animal study was to evaluate the histological response of the new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). Methods and Materials: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues.Samples were evaluated for the presence of inflammatory cell (mononuclear cell), vascular changes, fibrous tissue formation and present of giant cell. Comparisons between groups and time-periods were performed using the Kruskal-Wallis and Mann-Whitney U non-parametric tests. The level of significance was set at 0.05. Results: No significant difference was observed in tissue reactions and biocompatibility pattern of three sealers during 3 experimental periods ( P
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Cytotoxicity of a New Nano Zinc-Oxide Eugenol Sealer on Murine Fibroblasts
iranian endodontic journal, 2015Co-Authors: Maryam Javidi, Mina Zarei, Salma Omidi, Ahmad Ghorbani, Maryam Gharechahi, Maryam Shayani RadAbstract:Introduction: The aim of this study was to evaluate the cytotoxicity of a new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with AH-26 and Pulpdent root canal sealers. Methods and Materials: The L929 mouse fibroblast cells were cultivated and incubated for 24, 48 or 72 h with different dilutions (1/1, 1/2, 1/4, 1/8, 1/16 and 1/32) of culture media previously exposed to either of the test sealers naming NZOE, AH-26 or Pulpdent. At the end of incubation period, the effect of sealers on cell viability was evaluated using Mosmann’s Tetrazolium Toxicity (MTT) colorimetric assay. The data was compared using the one-way analysis of variance (ANOVA) followed by the Tukey’s post hoc test for multiple comparisons. Results: After 24, 48 or 72 h, both NZOE and Pulpdent sealers inhibited cell viability at 1/1, 1/2 and 1/8 dilutions. Within the 24 and 48 h, the AH-26 sealer reduced the cell viability at all dilutions except the 1/32 solution; however after 72 h even the 1/32 dilution was cytotoxic. Conclusion: The biocompatibility of the nano Zinc-Oxide Eugenol sealer was comparable to Pulpdent sealer and lower than AH-26. Keywords: Cytotoxicity; MTT Assay; Nanoparticles; Root Canal Sealer; Zinc-Oxide Eugenol
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Cytotoxicity of a New Nano Zinc-Oxide Eugenol Sealer on
2015Co-Authors: Maryam Javidi, Mina Zarei, Salma Omidi, Ahmad Ghorbani, Maryam Gharechahi, Maryam Shayani RadAbstract:Article Type: Original Article Introduction: The aim of this study was to evaluate the cytotoxicity of a new nano Zinc- Oxide Eugenol (NZOE) sealer in comparison with AH-26 and Pulpdent root canal sealers. Methods and Materials: The L929 mouse fibroblast cells were cultivated and incubated for 24, 48 or 72 h with different dilutions (1/1, 1/2, 1/4, 1/8, 1/16 and 1/32) of culture media previously exposed to either of the test sealers naming NZOE, AH-26 or Pulpdent. At the end of incubation period, the effect of sealers on cell viability was evaluated using Mosmann's Tetrazolium Toxicity (MTT) colorimetric assay. The data was compared using the one-way analysis of variance (ANOVA) followed by the Tukey's post hoc test for multiple comparisons. Results: After 24, 48 or 72 h, both NZOE and Pulpdent sealers inhibited cell viability at 1/1, 1/2 and 1/8 dilutions. Within the 24 and 48 h, the AH-26 sealer reduced the cell viability at all dilutions except the 1/32 solution; however after 72 h even the 1/32 dilution was cytotoxic. Conclusion: The biocompatibility of the nano Zinc- Oxide Eugenol sealer was comparable to Pulpdent sealer and lower than AH-26.
Mina Zarei - One of the best experts on this subject based on the ideXlab platform.
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subcutaneous connective tissue reaction to a new nano Zinc Oxide Eugenol sealer in rat model
iranian endodontic journal, 2017Co-Authors: Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amir Hossein JafarianAbstract:Introduction: The aim of this animal study was to evaluate the histological response of the new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). Methods and Materials: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues.Samples were evaluated for the presence of inflammatory cell (mononuclear cell), vascular changes, fibrous tissue formation and present of giant cell. Comparisons between groups and time-periods were performed using the Kruskal-Wallis and Mann-Whitney U non-parametric tests. The level of significance was set at 0.05. Results: No significant difference was observed in tissue reactions and biocompatibility pattern of three sealers during 3 experimental periods ( P <0.05). In all groups the tissue behavior showed tendency to decrease the irritation effect over time. Conclusion: The new nano Zinc-Oxide Eugenol sealer has histocompatibility properties comparable to conventional commercial sealers. Keywords: Biocompatibility; Nanoparticle; Tissue Reaction; Zinc-Oxide Eugenol
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Tooth Discoloration Resulting from a Nano Zinc Oxide-Eugenol Sealer.
iranian endodontic journal, 2017Co-Authors: Mina Zarei, Maryam Javidi, Maryam Gharechahi, Marzieh Jafari, Pedram Javidi, Maryam Shayani RadAbstract:Introduction: A desirable quality of any endodontic sealer is its ability to be tooth color friendly. Therefore the aim of the present study was to evaluate the tooth discoloration potential of a nano Zinc Oxide-Eugenol (NZOE) sealer. Methods and Materials: In order to evaluate tooth discoloration, the pulp chamber of 60 human maxillary central and lateral incisors were filled with one of the sealers, naming AH-26 (resin-based sealer), Pulpdent sealer (ZOE-based) and a NZOE experimental sealer. Color measurements was assessed at the baseline (before placement of sealers) (T0), 24 h (T1) and 72 h (T2) h, 1-week (T3), and 1-month (T4) after the placement of sealers using the Easy Shade spectrophotometer. Data were analyzed in SPSS software using one-way ANOVA, and repeated measured ANOVA. Results: No significant differences were observed when the paired comparison test was performed ( P >0.05). Conclusion: The tested nZOE sealer had similar tooth discoloration potential in comparison with AH-26 and ZOE sealer. Keywords: Nano Particle; Root Canal Sealer; Tooth Discoloration; Spectrophotometry; Zinc-Oxide Eugenol
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Subcutaneous Connective Tissue Reaction to a New Nano Zinc-Oxide Eugenol Sealer in Rat Model
iranian endodontic journal, 2017Co-Authors: Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amir Hossein JafarianAbstract:Introduction: The aim of this animal study was to evaluate the histological response of the new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). Methods and Materials: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues.Samples were evaluated for the presence of inflammatory cell (mononuclear cell), vascular changes, fibrous tissue formation and present of giant cell. Comparisons between groups and time-periods were performed using the Kruskal-Wallis and Mann-Whitney U non-parametric tests. The level of significance was set at 0.05. Results: No significant difference was observed in tissue reactions and biocompatibility pattern of three sealers during 3 experimental periods ( P
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Cytotoxicity of a New Nano Zinc-Oxide Eugenol Sealer on Murine Fibroblasts
iranian endodontic journal, 2015Co-Authors: Maryam Javidi, Mina Zarei, Salma Omidi, Ahmad Ghorbani, Maryam Gharechahi, Maryam Shayani RadAbstract:Introduction: The aim of this study was to evaluate the cytotoxicity of a new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with AH-26 and Pulpdent root canal sealers. Methods and Materials: The L929 mouse fibroblast cells were cultivated and incubated for 24, 48 or 72 h with different dilutions (1/1, 1/2, 1/4, 1/8, 1/16 and 1/32) of culture media previously exposed to either of the test sealers naming NZOE, AH-26 or Pulpdent. At the end of incubation period, the effect of sealers on cell viability was evaluated using Mosmann’s Tetrazolium Toxicity (MTT) colorimetric assay. The data was compared using the one-way analysis of variance (ANOVA) followed by the Tukey’s post hoc test for multiple comparisons. Results: After 24, 48 or 72 h, both NZOE and Pulpdent sealers inhibited cell viability at 1/1, 1/2 and 1/8 dilutions. Within the 24 and 48 h, the AH-26 sealer reduced the cell viability at all dilutions except the 1/32 solution; however after 72 h even the 1/32 dilution was cytotoxic. Conclusion: The biocompatibility of the nano Zinc-Oxide Eugenol sealer was comparable to Pulpdent sealer and lower than AH-26. Keywords: Cytotoxicity; MTT Assay; Nanoparticles; Root Canal Sealer; Zinc-Oxide Eugenol
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Cytotoxicity of a New Nano Zinc-Oxide Eugenol Sealer on
2015Co-Authors: Maryam Javidi, Mina Zarei, Salma Omidi, Ahmad Ghorbani, Maryam Gharechahi, Maryam Shayani RadAbstract:Article Type: Original Article Introduction: The aim of this study was to evaluate the cytotoxicity of a new nano Zinc- Oxide Eugenol (NZOE) sealer in comparison with AH-26 and Pulpdent root canal sealers. Methods and Materials: The L929 mouse fibroblast cells were cultivated and incubated for 24, 48 or 72 h with different dilutions (1/1, 1/2, 1/4, 1/8, 1/16 and 1/32) of culture media previously exposed to either of the test sealers naming NZOE, AH-26 or Pulpdent. At the end of incubation period, the effect of sealers on cell viability was evaluated using Mosmann's Tetrazolium Toxicity (MTT) colorimetric assay. The data was compared using the one-way analysis of variance (ANOVA) followed by the Tukey's post hoc test for multiple comparisons. Results: After 24, 48 or 72 h, both NZOE and Pulpdent sealers inhibited cell viability at 1/1, 1/2 and 1/8 dilutions. Within the 24 and 48 h, the AH-26 sealer reduced the cell viability at all dilutions except the 1/32 solution; however after 72 h even the 1/32 dilution was cytotoxic. Conclusion: The biocompatibility of the nano Zinc- Oxide Eugenol sealer was comparable to Pulpdent sealer and lower than AH-26.
Maryam Javidi - One of the best experts on this subject based on the ideXlab platform.
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subcutaneous connective tissue reaction to a new nano Zinc Oxide Eugenol sealer in rat model
iranian endodontic journal, 2017Co-Authors: Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amir Hossein JafarianAbstract:Introduction: The aim of this animal study was to evaluate the histological response of the new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). Methods and Materials: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues.Samples were evaluated for the presence of inflammatory cell (mononuclear cell), vascular changes, fibrous tissue formation and present of giant cell. Comparisons between groups and time-periods were performed using the Kruskal-Wallis and Mann-Whitney U non-parametric tests. The level of significance was set at 0.05. Results: No significant difference was observed in tissue reactions and biocompatibility pattern of three sealers during 3 experimental periods ( P <0.05). In all groups the tissue behavior showed tendency to decrease the irritation effect over time. Conclusion: The new nano Zinc-Oxide Eugenol sealer has histocompatibility properties comparable to conventional commercial sealers. Keywords: Biocompatibility; Nanoparticle; Tissue Reaction; Zinc-Oxide Eugenol
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Tooth Discoloration Resulting from a Nano Zinc Oxide-Eugenol Sealer.
iranian endodontic journal, 2017Co-Authors: Mina Zarei, Maryam Javidi, Maryam Gharechahi, Marzieh Jafari, Pedram Javidi, Maryam Shayani RadAbstract:Introduction: A desirable quality of any endodontic sealer is its ability to be tooth color friendly. Therefore the aim of the present study was to evaluate the tooth discoloration potential of a nano Zinc Oxide-Eugenol (NZOE) sealer. Methods and Materials: In order to evaluate tooth discoloration, the pulp chamber of 60 human maxillary central and lateral incisors were filled with one of the sealers, naming AH-26 (resin-based sealer), Pulpdent sealer (ZOE-based) and a NZOE experimental sealer. Color measurements was assessed at the baseline (before placement of sealers) (T0), 24 h (T1) and 72 h (T2) h, 1-week (T3), and 1-month (T4) after the placement of sealers using the Easy Shade spectrophotometer. Data were analyzed in SPSS software using one-way ANOVA, and repeated measured ANOVA. Results: No significant differences were observed when the paired comparison test was performed ( P >0.05). Conclusion: The tested nZOE sealer had similar tooth discoloration potential in comparison with AH-26 and ZOE sealer. Keywords: Nano Particle; Root Canal Sealer; Tooth Discoloration; Spectrophotometry; Zinc-Oxide Eugenol
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Subcutaneous Connective Tissue Reaction to a New Nano Zinc-Oxide Eugenol Sealer in Rat Model
iranian endodontic journal, 2017Co-Authors: Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amir Hossein JafarianAbstract:Introduction: The aim of this animal study was to evaluate the histological response of the new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). Methods and Materials: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues.Samples were evaluated for the presence of inflammatory cell (mononuclear cell), vascular changes, fibrous tissue formation and present of giant cell. Comparisons between groups and time-periods were performed using the Kruskal-Wallis and Mann-Whitney U non-parametric tests. The level of significance was set at 0.05. Results: No significant difference was observed in tissue reactions and biocompatibility pattern of three sealers during 3 experimental periods ( P
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Cytotoxicity of a New Nano Zinc-Oxide Eugenol Sealer on Murine Fibroblasts
iranian endodontic journal, 2015Co-Authors: Maryam Javidi, Mina Zarei, Salma Omidi, Ahmad Ghorbani, Maryam Gharechahi, Maryam Shayani RadAbstract:Introduction: The aim of this study was to evaluate the cytotoxicity of a new nano Zinc-Oxide Eugenol (NZOE) sealer in comparison with AH-26 and Pulpdent root canal sealers. Methods and Materials: The L929 mouse fibroblast cells were cultivated and incubated for 24, 48 or 72 h with different dilutions (1/1, 1/2, 1/4, 1/8, 1/16 and 1/32) of culture media previously exposed to either of the test sealers naming NZOE, AH-26 or Pulpdent. At the end of incubation period, the effect of sealers on cell viability was evaluated using Mosmann’s Tetrazolium Toxicity (MTT) colorimetric assay. The data was compared using the one-way analysis of variance (ANOVA) followed by the Tukey’s post hoc test for multiple comparisons. Results: After 24, 48 or 72 h, both NZOE and Pulpdent sealers inhibited cell viability at 1/1, 1/2 and 1/8 dilutions. Within the 24 and 48 h, the AH-26 sealer reduced the cell viability at all dilutions except the 1/32 solution; however after 72 h even the 1/32 dilution was cytotoxic. Conclusion: The biocompatibility of the nano Zinc-Oxide Eugenol sealer was comparable to Pulpdent sealer and lower than AH-26. Keywords: Cytotoxicity; MTT Assay; Nanoparticles; Root Canal Sealer; Zinc-Oxide Eugenol
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Cytotoxicity of a New Nano Zinc-Oxide Eugenol Sealer on
2015Co-Authors: Maryam Javidi, Mina Zarei, Salma Omidi, Ahmad Ghorbani, Maryam Gharechahi, Maryam Shayani RadAbstract:Article Type: Original Article Introduction: The aim of this study was to evaluate the cytotoxicity of a new nano Zinc- Oxide Eugenol (NZOE) sealer in comparison with AH-26 and Pulpdent root canal sealers. Methods and Materials: The L929 mouse fibroblast cells were cultivated and incubated for 24, 48 or 72 h with different dilutions (1/1, 1/2, 1/4, 1/8, 1/16 and 1/32) of culture media previously exposed to either of the test sealers naming NZOE, AH-26 or Pulpdent. At the end of incubation period, the effect of sealers on cell viability was evaluated using Mosmann's Tetrazolium Toxicity (MTT) colorimetric assay. The data was compared using the one-way analysis of variance (ANOVA) followed by the Tukey's post hoc test for multiple comparisons. Results: After 24, 48 or 72 h, both NZOE and Pulpdent sealers inhibited cell viability at 1/1, 1/2 and 1/8 dilutions. Within the 24 and 48 h, the AH-26 sealer reduced the cell viability at all dilutions except the 1/32 solution; however after 72 h even the 1/32 dilution was cytotoxic. Conclusion: The biocompatibility of the nano Zinc- Oxide Eugenol sealer was comparable to Pulpdent sealer and lower than AH-26.
