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Sun Qin-feng – One of the best experts on this subject based on the ideXlab platform.
Study of Acute Inflammation during root canal therapy of residual roots and crownsChinese Journal of Conservative Dentistry, 2004Co-Authors: Sun Qin-fengAbstract:
AIM:To study the reason and incidence of Acute Inflammation during root canal therapy of residual roots and crowns.METHODS:Eighty-three patients were randomly assigned to either the one-appointment or two-appointments root canal therapy.The causes of Acute Inflammation were analyzed.RESULTS:The incidence of the Acute Inflammation from both methods had no significant difference,but the incidence of Acute phlegmon of two-appointment root canal therapy was more than that of one-appointments ( P 0.05).The Acute Inflammation was related to the root preparation,root filling and periapical leision.CONCLUSION:Root canal therapy should be done strictly.One-appointments root canal therapy may be employed in the treatment of residual roots and crowns. [
Kiyofumi Furusawa – One of the best experts on this subject based on the ideXlab platform.
Acute Inflammation in horizontal incompletely impacted third molar with radiolucency in the elderlyClinical interventions in aging, 2009Co-Authors: Minoru Yamaoka, Yusuke Ono, Masahide Ishizuka, Kouichi Yasuda, Takashi Uematsu, Masahiro Takahashi, Takayuki Uchihashi, Kiyofumi FurusawaAbstract:
Although radiolucency has been shown as a risk of infection, the poorly understood effects of aging on radiolucency correlate with Acute pericoronitis, which has a high risk of infection extending any complications. We reviewed the records of 346 consecutive patients aged more than 41 years to evaluate whether pericoronal radiolucency below the crown in mandibular horizontal incompletely impacted third molars is related to Acute Inflammation. The frequency of Acute Inflammation in teeth with pericoronal radiolucency below the crown was similar to that in teeth without; however, the odds ratio of Acute Inflammation exhibited in women aged more than 61 years compared to women aged 41–50 years was 9.77 (95% confidence interval [CI]: 1.67–57.29; P <
Acute Inflammation at a mandibular solitary horizontal incompletely impacted molar.International journal of general medicine, 2009Co-Authors: Minoru Yamaoka, Yusuke Ono, Masahide Ishizuka, Yoko Hasumi-nakayama, Ryosuke Doto, Kouichi Yasuda, Takashi Uematsu, Kiyofumi FurusawaAbstract:
Acute Inflammation is frequently seen in the elderly around incompletely impacted molars located apart from molars or premolars. To identify the factors causing Acute Inflammation in the solitary molars without second molars or without second and first molars, ages of patients and rates of Acute Inflammation in 75 horizontal incompletely impacted mandibular molars in contact or not in contact with molars in subjects 41 years old or older were studied using orthopantomographs. Acute Inflammation was seen in nine third molars out of 48 third molars in contact with second molars (18.8%), whereas Acute Inflammation was seen in 11 molars out of 19 solitary molars without second molars or without first and second molars (57.9%) (p < 0.01). The mean age of 48 subjects with third molars in contact with the second molar was 50.42 +/- 7.62 years, and the mean age of 19 subjects with isolated molars was 65.16 +/- 10.41 years (p < 0.0001). These indicate that a solitary horizontal incompletely impacted molar leads more frequently to Acute Inflammation along with aging due to possible bone resorption resulting from teeth loss.
Radiolucency below the crown of mandibular horizontal incompletely impacted third molars and Acute Inflammation in men with diabetes.Clinical cosmetic and investigational dentistry, 2009Co-Authors: Minoru Yamaoka, Yusuke Ono, Masahide Ishizuka, Kouichi Yasuda, Takashi Uematsu, Kiyofumi FurusawaAbstract:
Although mandibular third molar has a high risk of infection extending any complications, the influence of diabetes on radiolucency and Acute Inflammation in pericoronitis remains unclear. The present study was to evaluate whether radiolucency below the crown is related to Acute Inflammation in mandibular horizontal incompletely impacted third molars and to review the records of 140 men more than 45 years with and without diabetes. The odds ratio of exhibiting Acute Inflammation was 3.38 (95% CI: 1.13-10.16, p < 0.05) and that of exhibiting severe Acute Inflammation was 15.38 (95% CI: 3.56-66.49, p < 0.0001), indicating an association of Acute pericoronitis in diabetes. The frequency of radiolucency below the crown and below the root in diabetics was similar to that in nondiabetics. However, the odds ratio of exhibiting both radiolucency below the crown and Acute Inflammation under the diabetic condition was 4.85 (95% CI: 1.60-14.73, p < 0.01), whereas that of diabetics showing both radiolucency below the root and Acute Inflammation was 0.46 (95% CI: 0.06-3.74, p = 0.74). Radiolucency below the crown and Acute Inflammation were associated with diabetes, but that below root and Acute Inflammation were not associated with diabetes, indicating that the region below the crown carries susceptibility to Acute pericoronitis, whereas the periodontium shows a protective effect against Acute pericoronitis.
Matthew Spite – One of the best experts on this subject based on the ideXlab platform.
Resolution of Acute Inflammation and the Role of Resolvins in Immunity, Thrombosis, and Vascular BiologyCirculation research, 2016Co-Authors: Brian E. Sansbury, Matthew SpiteAbstract:
Acute Inflammation is a host-protective response that is mounted in response to tissue injury and infection. Initiated and perpetuated by exogenous and endogenous mediators, Acute Inflammation must be resolved for tissue repair to proceed and for homeostasis to be restored. Resolution of Inflammation is an actively regulated process governed by an array of mediators as diverse as those that initiate Inflammation. Among these, resolvins have emerged as a genus of evolutionarily conserved proresolving mediators that act on specific cellular receptors to regulate leukocyte trafficking and blunt production of inflammatory mediators, while also promoting clearance of dead cells and tissue repair. Given that chronic unresolved Inflammation is emerging as a central causative factor in the development of cardiovascular diseases, an understanding of the endogenous processes that govern normal resolution of Acute Inflammation is critical for determining why sterile maladaptive cardiovascular Inflammation perpetuates. Here, we provide an overview of the process of resolution with a focus on the enzymatic biosynthesis and receptor-dependent actions of resolvins and related proresolving mediators in immunity, thrombosis, and vascular biology. We discuss how nutritional and current therapeutic approaches modulate resolution and propose that harnessing resolution concepts could potentially lead to the development of new approaches for treating chronic cardiovascular Inflammation in a manner that is not host disruptive.
novel lipid mediators promote resolution of Acute Inflammation impact of aspirin and statinsCirculation Research, 2010Co-Authors: Matthew Spite, Charles N. SerhanAbstract:
The resolution of Acute Inflammation is a process that allows for inflamed tissues to return to homeostasis. Resolution was held to be a passive process, a concept now overturned with new evidence demonstrating that resolution is actively orchestrated by distinct cellular events and endogenous chemical mediators. Among these, lipid mediators, such as the lipoxins, resolvins, protectins, and newly identified maresins, have emerged as a novel genus of potent and stereoselective players that counter-regulate excessive Acute Inflammation and stimulate molecular and cellular events that define resolution. Given that uncontrolled, chronic Inflammation is associated with many cardiovascular pathologies, an appreciation of the endogenous pathways and mediators that control timely resolution can open new terrain for therapeutic approaches targeted at stimulating resolution of local Inflammation, as well as correcting the impact of chronic Inflammation in cardiovascular disorders. Here, we overview and update the biosynthesis and actions of proresolving lipid mediators, highlighting their diverse protective roles relevant to vascular systems and their relation to aspirin and statin therapies.