The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform
Giovanni Rezza - One of the best experts on this subject based on the ideXlab platform.
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experimental studies of susceptibility of italian Aedes albopictus to zika virus
Eurosurveillance, 2016Co-Authors: Marco Di Luca, Francesco Severini, Luciano Toma, Daniela Boccolini, Roberto Romi, Maria Elena Remoli, Michela Sabbatucci, Caterina Rizzo, Giulietta Venturi, Giovanni RezzaAbstract:We report a study on vector competence of an Italian population of Aedes albopictus for Zika virus (ZIKV). Ae. albopictus was susceptible to ZIKV infection (infection rate: 10%), and the virus could disseminate and was secreted in the mosquito’s saliva (dissemination rate: 29%; transmission rate: 29%) after an extrinsic incubation period of 11 days. The observed vector competence was lower than that of an Ae. aegypti colony tested in parallel.
Marc Grandadam - One of the best experts on this subject based on the ideXlab platform.
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Aedes albopictus mosquito the main vector of the 2007 chikungunya outbreak in gabon
PLOS ONE, 2009Co-Authors: Frederic Pages, Dieudonne Nkoghe, Christophe N Peyrefitte, Fanny Jarjaval, Sylvain Brisse, Isabelle Iteman, Patrick Gravier, Marc GrandadamAbstract:The primary vector at the origin of the 2007 outbreak in Libreville, Gabon is identified as Aedes albopictus, trapped around the nearby French military camp. The Chikungunya virus was isolated from mosquitoes and found to be identical to the A226V circulating human strain. This is the first field study showing the role of the recently arrived species Aedes albopictus in Chikungunya virus transmission in Central Africa, and it demonstrates this species' role in modifying the epidemiological presentation of Chikungunya in Gabon.
Eric Leroy - One of the best experts on this subject based on the ideXlab platform.
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zika virus in gabon central africa 2007 a new threat from Aedes albopictus
PLOS Neglected Tropical Diseases, 2014Co-Authors: Gilda Grard, Illich Manfred Mombo, Dieudonne Nkoghe, Statiana Mboui Ondo, Melanie Caron, Davy Jiolle, Christophe Paupy, Didier Fontenille, Eric LeroyAbstract:Background Chikungunya and dengue viruses emerged in Gabon in 2007, with large outbreaks primarily affecting the capital Libreville and several northern towns. Both viruses subsequently spread to the south-east of the country, with new outbreaks occurring in 2010. The mosquito species Aedes albopictus, that was known as a secondary vector for both viruses, recently invaded the country and was the primary vector involved in the Gabonese outbreaks. We conducted a retrospective study of human sera and mosquitoes collected in Gabon from 2007 to 2010, in order to identify other circulating arboviruses. Methodology/Principal Findings Sample collections, including 4312 sera from patients presenting with painful febrile disease, and 4665 mosquitoes belonging to 9 species, split into 247 pools (including 137 pools of Aedes albopictus), were screened with molecular biology methods. Five human sera and two Aedes albopictus pools, all sampled in an urban setting during the 2007 outbreak, were positive for the flavivirus Zika (ZIKV). The ratio of Aedes albopictus pools positive for ZIKV was similar to that positive for dengue virus during the concomitant dengue outbreak suggesting similar mosquito infection rates and, presumably, underlying a human ZIKV outbreak. ZIKV sequences from the envelope and NS3 genes were amplified from a human serum sample. Phylogenetic analysis placed the Gabonese ZIKV at a basal position in the African lineage, pointing to ancestral genetic diversification and spread. Conclusions/Significance We provide the first direct evidence of human ZIKV infections in Gabon, and its first occurrence in the Asian tiger mosquito, Aedes albopictus. These data reveal an unusual natural life cycle for this virus, occurring in an urban environment, and potentially representing a new emerging threat due to this novel association with a highly invasive vector whose geographic range is still expanding across the globe.
Marco Di Luca - One of the best experts on this subject based on the ideXlab platform.
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experimental studies of susceptibility of italian Aedes albopictus to zika virus
Eurosurveillance, 2016Co-Authors: Marco Di Luca, Francesco Severini, Luciano Toma, Daniela Boccolini, Roberto Romi, Maria Elena Remoli, Michela Sabbatucci, Caterina Rizzo, Giulietta Venturi, Giovanni RezzaAbstract:We report a study on vector competence of an Italian population of Aedes albopictus for Zika virus (ZIKV). Ae. albopictus was susceptible to ZIKV infection (infection rate: 10%), and the virus could disseminate and was secreted in the mosquito’s saliva (dissemination rate: 29%; transmission rate: 29%) after an extrinsic incubation period of 11 days. The observed vector competence was lower than that of an Ae. aegypti colony tested in parallel.
Didier Fontenille - One of the best experts on this subject based on the ideXlab platform.
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zika virus in gabon central africa 2007 a new threat from Aedes albopictus
PLOS Neglected Tropical Diseases, 2014Co-Authors: Gilda Grard, Illich Manfred Mombo, Dieudonne Nkoghe, Statiana Mboui Ondo, Melanie Caron, Davy Jiolle, Christophe Paupy, Didier Fontenille, Eric LeroyAbstract:Background Chikungunya and dengue viruses emerged in Gabon in 2007, with large outbreaks primarily affecting the capital Libreville and several northern towns. Both viruses subsequently spread to the south-east of the country, with new outbreaks occurring in 2010. The mosquito species Aedes albopictus, that was known as a secondary vector for both viruses, recently invaded the country and was the primary vector involved in the Gabonese outbreaks. We conducted a retrospective study of human sera and mosquitoes collected in Gabon from 2007 to 2010, in order to identify other circulating arboviruses. Methodology/Principal Findings Sample collections, including 4312 sera from patients presenting with painful febrile disease, and 4665 mosquitoes belonging to 9 species, split into 247 pools (including 137 pools of Aedes albopictus), were screened with molecular biology methods. Five human sera and two Aedes albopictus pools, all sampled in an urban setting during the 2007 outbreak, were positive for the flavivirus Zika (ZIKV). The ratio of Aedes albopictus pools positive for ZIKV was similar to that positive for dengue virus during the concomitant dengue outbreak suggesting similar mosquito infection rates and, presumably, underlying a human ZIKV outbreak. ZIKV sequences from the envelope and NS3 genes were amplified from a human serum sample. Phylogenetic analysis placed the Gabonese ZIKV at a basal position in the African lineage, pointing to ancestral genetic diversification and spread. Conclusions/Significance We provide the first direct evidence of human ZIKV infections in Gabon, and its first occurrence in the Asian tiger mosquito, Aedes albopictus. These data reveal an unusual natural life cycle for this virus, occurring in an urban environment, and potentially representing a new emerging threat due to this novel association with a highly invasive vector whose geographic range is still expanding across the globe.
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geographic distribution and developmental sites of Aedes albopictus diptera culicidae during a chikungunya epidemic event
Vector-borne and Zoonotic Diseases, 2008Co-Authors: Helene Delatte, Christophe Paupy, Jeansebastien Dehecq, J Thiria, Caroline Domerg, Didier FontenilleAbstract:Aedes albopictus is generally considered to have a low vectorial capacity because of its lack of host specificity. Nevertheless, it has been the sole vector of the Chikungunya virus in recent explo...
