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Hugues Duffau - One of the best experts on this subject based on the ideXlab platform.

  • permanent anosmia and Ageusia after resection of a left temporoinsular low grade glioma anatomofunctional considerations
    Journal of Neurosurgery, 2012
    Co-Authors: Eduardo Santamaria Carvalhal Ribas, Hugues Duffau
    Abstract:

    Five percent of the general population has olfactory or gustatory disorders, although most do not complain about it. However, in some cases, these symptoms can be disabling and may affect quality of life. Anosmia was reported as a possible complication following head injury and neurosurgical procedures, particularly after the resection of tumors located in the anterior fossa and the treatment of aneurysms in the anterior circulation. Nonetheless, in all of these situations, olfactory dysfunction could be explained by damage to the peripheral olfactory system. Here, the authors report a case of complete anosmia associated with Ageusia following awake resection of a low-grade glioma involving the left temporoinsular region, with no recovery during a follow-up of 3 years. The frontal lobe was not retracted, and the olfactory tract was not visualized during surgery; therefore, postoperative anosmia and Ageusia are likely explained by damage to the cortex and central pathways responsible for these senses. The ...

  • permanent anosmia and Ageusia after resection of a left temporoinsular low grade glioma anatomofunctional considerations
    Journal of Neurosurgery, 2012
    Co-Authors: Eduardo Carvalhal Ribas, Hugues Duffau
    Abstract:

    Five percent of the general population has olfactory or gustatory disorders, although most do not complain about it. However, in some cases, these symptoms can be disabling and may affect quality of life. Anosmia was reported as a possible complication following head injury and neurosurgical procedures, particularly after the resection of tumors located in the anterior fossa and the treatment of aneurysms in the anterior circulation. Nonetheless, in all of these situations, olfactory dysfunction could be explained by damage to the peripheral olfactory system. Here, the authors report a case of complete anosmia associated with Ageusia following awake resection of a low-grade glioma involving the left temporoinsular region, with no recovery during a follow-up of 3 years. The frontal lobe was not retracted, and the olfactory tract was not visualized during surgery; therefore, postoperative anosmia and Ageusia are likely explained by damage to the cortex and central pathways responsible for these senses. The authors suggest that the patient might have had a subclinical right hemianosmia before surgery, which is a common condition. After resection of the central structures critical for smell and taste processing in the left hemisphere, the patient could have finally had bilateral and complete olfactory and gustatory loss. This is the first known report of permanent anosmia and Ageusia following glioma surgery. Because these symptoms might have been underestimated, more attention should be devoted to olfaction and taste, especially with regard to possible subclinical preoperative deficit.

Luigi Angelo Vaira - One of the best experts on this subject based on the ideXlab platform.

  • potential pathogenesis of Ageusia and anosmia in covid 19 patients
    International Forum of Allergy & Rhinology, 2020
    Co-Authors: Luigi Angelo Vaira, Giovanni Salzano, Alessandro G Fois, Pasquale Piombino, Giacomo De Riu
    Abstract:

    From the first reports, Ageusia and anosmia appear to be frequent clinical features in coronavirus disease 19 (COVID‐19) patients. We have performed a survey of the literature, analyzing the possible causes of these chemosensory alterations, which may be useful as a starting point for specific further studies.This article is protected by copyright. All rights reserved

  • objective evaluation of anosmia and Ageusia in covid 19 patients single center experience on 72 cases
    Head and Neck-journal for The Sciences and Specialties of The Head and Neck, 2020
    Co-Authors: Luigi Angelo Vaira, Giovanna Deiana, Alessandro G Fois, Pietro Pirina, G Madeddu, Andrea De Vito, Sergio Babudieri, Marzia Petrocelli, Antonello Serra, Francesco Bussu
    Abstract:

    BACKGROUND: The first European case series are detecting a very high frequency of chemosensitive disorders in COVID-19 patients, ranging between 19.4% and 88%. METHODS: Olfactory and gustatory function was objectively tested in 72 COVID-19 patients treated at University Hospital of Sassari. RESULTS: Overall, 73.6% of the patients reported having or having had chemosensitive disorders. Olfactory assessment showed variable degree hyposmia in 60 cases and anosmia in two patients. Gustatory assessment revealed hypogeusia in 33 cases and complete Ageusia in one patient. Statistically significant differences in chemosensitive recovery were detected based on age and distance from the onset of clinical manifestations. CONCLUSION: Olfactory and gustatory dysfunctions represent common clinical findings in COVID-19 patients. Otolaryngologists and head-neck surgeons must by now keep this diagnostic option in mind when evaluating cases of Ageusia and nonspecific anosmia that arose suddenly and are not associated with rhinitis symptoms.

  • objective evaluation of anosmia and Ageusia in covid 19 patients a single center experience on 72 cases
    Authorea Preprints, 2020
    Co-Authors: Luigi Angelo Vaira
    Abstract:

    Background. The firsts European case series are detecting a very high frequency of chemosensitive disorders in COVID-19 patients, ranging between 19.4% and 88%.Methods. Olfactory and gustatory function was objectively tested in 72 COVID-19 patients treated at University Hospital of Sassari.Results Overall, 73.6% of the patients reported having or having had chemosensitive disorders. Olfactory assessment showed variable degree hyposmia in 60 cases and anosmia in 2 patients. Gustatory assessment revealed hypogeusia in 33 cases and complete Ageusia in 1 patient. Statistically significant differences in chemosensitive recovery were detected based on age and distance from the onset of clinical manifestations.Conclusion. Olfactory and gustatory dysfunctions represent common clinical findings in COVID-19 patients. Otolaryngologists and head-neck surgeons must by now keep this diagnostic option in mind when evaluating cases of Ageusia and nonspecific anosmia that arose suddenly and are not associated with rhinitis symptoms

  • anosmia and Ageusia common findings in covid 19 patients
    Laryngoscope, 2020
    Co-Authors: Luigi Angelo Vaira, Giovanni Salzano, Giovanna Deiana, Giacomo De Riu
    Abstract:

    In a not negligible number of patients affected by COVID-19 (coronavirus disease 2019), especially if paucisymptomatic, anosmia and Ageusia can represent the first or only symptomatology present. Laryngoscope, 130:1787-1787, 2020.

Eduardo Santamaria Carvalhal Ribas - One of the best experts on this subject based on the ideXlab platform.

  • permanent anosmia and Ageusia after resection of a left temporoinsular low grade glioma anatomofunctional considerations
    Journal of Neurosurgery, 2012
    Co-Authors: Eduardo Santamaria Carvalhal Ribas, Hugues Duffau
    Abstract:

    Five percent of the general population has olfactory or gustatory disorders, although most do not complain about it. However, in some cases, these symptoms can be disabling and may affect quality of life. Anosmia was reported as a possible complication following head injury and neurosurgical procedures, particularly after the resection of tumors located in the anterior fossa and the treatment of aneurysms in the anterior circulation. Nonetheless, in all of these situations, olfactory dysfunction could be explained by damage to the peripheral olfactory system. Here, the authors report a case of complete anosmia associated with Ageusia following awake resection of a low-grade glioma involving the left temporoinsular region, with no recovery during a follow-up of 3 years. The frontal lobe was not retracted, and the olfactory tract was not visualized during surgery; therefore, postoperative anosmia and Ageusia are likely explained by damage to the cortex and central pathways responsible for these senses. The ...

Eduardo Carvalhal Ribas - One of the best experts on this subject based on the ideXlab platform.

  • permanent anosmia and Ageusia after resection of a left temporoinsular low grade glioma anatomofunctional considerations
    Journal of Neurosurgery, 2012
    Co-Authors: Eduardo Carvalhal Ribas, Hugues Duffau
    Abstract:

    Five percent of the general population has olfactory or gustatory disorders, although most do not complain about it. However, in some cases, these symptoms can be disabling and may affect quality of life. Anosmia was reported as a possible complication following head injury and neurosurgical procedures, particularly after the resection of tumors located in the anterior fossa and the treatment of aneurysms in the anterior circulation. Nonetheless, in all of these situations, olfactory dysfunction could be explained by damage to the peripheral olfactory system. Here, the authors report a case of complete anosmia associated with Ageusia following awake resection of a low-grade glioma involving the left temporoinsular region, with no recovery during a follow-up of 3 years. The frontal lobe was not retracted, and the olfactory tract was not visualized during surgery; therefore, postoperative anosmia and Ageusia are likely explained by damage to the cortex and central pathways responsible for these senses. The authors suggest that the patient might have had a subclinical right hemianosmia before surgery, which is a common condition. After resection of the central structures critical for smell and taste processing in the left hemisphere, the patient could have finally had bilateral and complete olfactory and gustatory loss. This is the first known report of permanent anosmia and Ageusia following glioma surgery. Because these symptoms might have been underestimated, more attention should be devoted to olfaction and taste, especially with regard to possible subclinical preoperative deficit.

Luke S P Moore - One of the best experts on this subject based on the ideXlab platform.

  • new onset anosmia and Ageusia in adult patients diagnosed with sars cov 2 infection
    Clinical Microbiology and Infection, 2020
    Co-Authors: Aatish Patel, Esmita Charani, David Ariyanayagam, Ahmed Abdulaal, Nabeela Mughal, Sarah J Denny, Luke S P Moore
    Abstract:

    Abstract Objectives We investigated the prevalence of anosmia and Ageusia in adult patients with a laboratory-confirmed diagnosis of infection with severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2). Methods This was a retrospective observational analysis of patients infected with SARS-CoV-2 admitted to hospital or managed in the community and their household contacts across a London population during the period March 1st to April 1st, 2020. Symptomatology and duration were extracted from routinely collected clinical data and follow-up telephone consultations. Descriptive statistics were used. Results Of 386 patients, 141 (92 community patients, 49 discharged inpatients) were included for analysis; 77/141 (55%) reported anosmia and Ageusia, nine reported only Ageusia and three only anosmia. The median onset of anosmia in relation to onset of SARS-CoV-2 disease (COVID-19) symptoms (as defined by the Public Health England case definition) was 4 days (interquartile range (IQR) 5). Median duration of anosmia was 8 days (IQR 16). Median duration of COVID-19 symptoms in community patients was 10 days (IQR 8) versus 18 days (IQR 13.5) in admitted patients. As of April 1, 45 patients had ongoing COVID-19 symptoms and/or anosmia; 107/141 (76%) patients had household contacts, and of 185 non-tested household contacts 79 (43%) had COVID-19 symptoms with 46/79 (58%) reporting anosmia. Six household contacts had anosmia only. Conclusions Over half of the positive patients reported anosmia and Ageusia, suggesting that these should be added to the case definition and used to guide self-isolation protocols. This adaptation may be integral to case findings in the absence of population-level testing. Until we have successful population-level vaccination coverage, these steps remain critical in the current and future waves of this pandemic.

  • new onset anosmia and Ageusia in adult patients diagnosed with sars cov 2 in a london community and secondary care population
    Social Science Research Network, 2020
    Co-Authors: Aatish Patel, Esmita Charani, David Ariyanayagam, Ahmed Abdulaal, Sarah K Denny, Nabeela Mughal, Luke S P Moore
    Abstract:

    Background: We investigated the prevalence of anosmia and Ageusia in adult patients with a laboratory confirmed diagnosis of severe acute respiratory distress s