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Alopecia Universalis

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Renu Kandpal – One of the best experts on this subject based on the ideXlab platform.

  • rare presentation of Alopecia Universalis congenita and twenty nail dystrophy in siblings
    International Journal of Trichology, 2017
    Co-Authors: Debdeep Mitra, Reetu Agarwal, Ajay Chopra, Renu Kandpal

    Abstract:

    Congenital Alopecia Universalis is one of the rarest anomaly which involves skin and appendages. The inheritance pattern can be autosomal recessive, X-linked recessive, or autosomal dominant. However, the most common is autosomal recessive form and it is the most severe phenotype. Twenty-nail dystrophy refers to the condition in which all the twenty nails are affected in the form of excessive ridging and nail plate roughness leading to unsightly lustureless nails. We report a rare case of two siblings with Alopecia Universalis congenita with twenty-nail dystrophy. To the best of our knowledge, this case is the first case to be reported with such association in both siblings. This case reports highlights the fact that Alopecia areata is an autoimmune disease with a genetic predisposition as in our case both siblings had Alopecia Universalis and nail dystrophy. There was no evidence of any other ectodermal dyplasia and had normal teeth and seat glands. The skin biopsy ruled out congenital atrichia and was suggestive of Alopecia areata.

Toshio Hamada – One of the best experts on this subject based on the ideXlab platform.

  • twenty nail dystrophy trachyonychia caused by lichen planus in a patient with Alopecia Universalis and ichthyosis vulgaris
    Journal of The American Academy of Dermatology, 1995
    Co-Authors: Shoji Taniguchi, Haruo Kutsuna, Yukiko Tani, Kazuhiro Kawahira, Toshio Hamada

    Abstract:

    A 7-year-old girl with Alopecia Universalis had dystrophy of all 20 nails. A nail biopsy specimen disclosed features of lichen planus. The patient also had ichthyosis vulgaris and hypogammaglobulinemia. We are not aware of any previous reports of these associations, which we believe to be noncoincidental.

Debdeep Mitra – One of the best experts on this subject based on the ideXlab platform.

  • rare presentation of Alopecia Universalis congenita and twenty nail dystrophy in siblings
    International Journal of Trichology, 2017
    Co-Authors: Debdeep Mitra, Reetu Agarwal, Ajay Chopra, Renu Kandpal

    Abstract:

    Congenital Alopecia Universalis is one of the rarest anomaly which involves skin and appendages. The inheritance pattern can be autosomal recessive, X-linked recessive, or autosomal dominant. However, the most common is autosomal recessive form and it is the most severe phenotype. Twenty-nail dystrophy refers to the condition in which all the twenty nails are affected in the form of excessive ridging and nail plate roughness leading to unsightly lustureless nails. We report a rare case of two siblings with Alopecia Universalis congenita with twenty-nail dystrophy. To the best of our knowledge, this case is the first case to be reported with such association in both siblings. This case reports highlights the fact that Alopecia areata is an autoimmune disease with a genetic predisposition as in our case both siblings had Alopecia Universalis and nail dystrophy. There was no evidence of any other ectodermal dyplasia and had normal teeth and seat glands. The skin biopsy ruled out congenital atrichia and was suggestive of Alopecia areata.