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Amino Group

The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform

Pinaki Talukdar – 1st expert on this subject based on the ideXlab platform

  • a 1 3 Amino Group migration route to form acrylamidines
    ChemInform, 2014
    Co-Authors: Dinesh Pratapsinh Chauhan, Sreejith Jayasree Varma, Arjun Vijeta, Pallavi Banerjee, Pinaki Talukdar

    Abstract:

    A novel route for the synthesis of acrylamidines by Cu-catalyzed addition of tosylazide to 1-Aminopropines and subsequent intramolecular addition of nucleophiles to ketenimines with 1,3-Amino Group migration is presented.

  • a 1 3 Amino Group migration route to form acrylamidines
    Chemical Communications, 2014
    Co-Authors: Dinesh Pratapsinh Chauhan, Sreejith Jayasree Varma, Arjun Vijeta, Pallavi Banerjee, Pinaki Talukdar

    Abstract:

    A novel 1,3-Amino Group migration strategy for the synthesis of acrylamidines is presented. Cu(I) catalyzed reaction of N,N-disubstituted propargylamine with tosylazide generates a highly reactive ketenimine intermediate which is trapped by a tethered Amino Group leading to the rearrangement reaction.

Kishore V L Parsa – 2nd expert on this subject based on the ideXlab platform

  • vinylic Amino Group activation a new and general strategy leading to functionalized fused heteroaromatics
    ChemInform, 2013
    Co-Authors: Rajnikanth Sunke, Raju Adepu, Ravikumar Kapavarapu, Swetha Chintala, Chandana Lakshmi T Meda, Kishore V L Parsa

    Abstract:

    With a view to find novel inhibitors of phosphodiesterase 4 (PDE4), a series of tetracyclic heteroaromatics (IV) and (VII) is prepared by intramolecular cyclization of corresponding amines (III) and (VI).

  • vinylic Amino Group activation a new and general strategy leading to functionalized fused heteroaromatics
    Chemical Communications, 2013
    Co-Authors: Rajnikanth Sunke, Raju Adepu, Ravikumar Kapavarapu, Swetha Chintala, Chandana Lakshmi T Meda, Kishore V L Parsa

    Abstract:

    A conceptually new and general strategy has been developed for the construction of a benzimidazole or a benzoxazole ring fused with isoquinolinone affording a diverse and unique class of small molecules as potential and novel inhibitors of PDE4.

Xigeng Zhou – 3rd expert on this subject based on the ideXlab platform

  • lanthanide catalyzed reversible alkynyl exchange by carbon carbon single bond cleavage assisted by a secondary Amino Group
    ChemInform, 2016
    Co-Authors: Yinlin Shao, Fangjun Zhang, Jie Zhang, Xigeng Zhou

    Abstract:

    Lanthanide-catalyzed alkynyl exchange through C—C single-bond cleavage assisted by a secondary Amino Group is reported.

  • lanthanide catalyzed reversible alkynyl exchange by carbon carbon single bond cleavage assisted by a secondary Amino Group
    Angewandte Chemie, 2016
    Co-Authors: Yinlin Shao, Fangjun Zhang, Jie Zhang, Xigeng Zhou

    Abstract:

    Lanthanide-catalyzed alkynyl exchange through C−C single-bond cleavage assisted by a secondary Amino Group is reported. A lanthanide amido complex is proposed as a key intermediate, which undergoes unprecedented reversible β-alkynyl elimination followed by alkynyl exchange and imine reinsertion. The in situ homo- and cross-dimerization of the liberated alkyne can serve as an additional driving force to shift the metathesis equilibrium to completion. This reaction is formally complementary to conventional alkyne metathesis and allows the selective transformation of internal propargylamines into those bearing different substituents on the alkyne terminus in moderate to excellent yields under operationally simple reaction conditions.