The Experts below are selected from a list of 27 Experts worldwide ranked by ideXlab platform
Nancy Hildebrandt - One of the best experts on this subject based on the ideXlab platform.
-
on the structure of verbal short term memory and its functional role in sentence comprehension evidence from neuropsychology
Cognitive Neuropsychology, 1991Co-Authors: Gloria Waters, David Caplan, Nancy HildebrandtAbstract:Abstract We present a case of a patient with a disorder of short-term memory. BO has a reduced span (2 to 3 items), no recency effect in free recall, and rapid forgetting in Brown-Peterson tasks, establishing her as a patient with impaired short-term verbal memory functions. She shows no effect of either phonological similarity or word length in recall of auditory or written word lists, but some recency effect under recall-from-end conditions and better performance on Brown-Peterson tasks in an unfilled than in a filled condition. This pattern of performance is interpreted as being consistent with a primary Disturbance of the articulatory rehearsal processes of S.T.M. and possibly some impairment of the phonological store (using Baddeley's 1986 terminology). Her Aphasic Disturbance—apraxia of speech—is also consistent with a Disturbance of articulatory rehearsal. BO shows a retained ability to extract phonology from print, including an ability to apply sublexical grapheme-phoneme correspondences, thus ind...
Joerg-christian Tonn - One of the best experts on this subject based on the ideXlab platform.
-
Intraoperative mapping of language functions: a longitudinal neurolinguistic analysis.
Journal of Neurosurgery, 2008Co-Authors: J. Ilmberger, Maximilian I. Ruge, Friedrich-wilhelm Kreth, Josef Briegel, Hans-juergen Reulen, Joerg-christian TonnAbstract:Object This prospective longitudinally designed study was conducted to evaluate language functions pre- and postoperatively in patients who underwent microsurgical treatment of tumors in close proximity to or within language areas and to detect those patients at risk for a postoperative Aphasic Disturbance. Methods Between 1991 and 2005, 153 awake craniotomies with subsequent cortical mapping of language functions were performed in 149 patients. Language functions were assessed using a standardized test battery. Risk factors were obtained from multivariate logistic regression models. Results Language mapping was able to be performed in all patients, and complete tumor resection was achieved in 48.4%. Within 21 days after surgery a new language deficit (Aphasic Disturbance) was observed in 41 (32%) of the 128 cases without preoperative deficits. There were a total of 60 cases involving postoperative Aphasic Disturbances, including cases both with and without preoperative Disturbances. Risk factors for post...
Wolf-dieter Heiss - One of the best experts on this subject based on the ideXlab platform.
-
Preoperative activation and intraoperative stimulation of language-related areas in patients with glioma
Neurosurgery, 1997Co-Authors: Karl Herholz, Hans-jürgen Reulen, Hans-martin Von Stockhausen, Alexander Thiel, Josef Llmberger, Josef Kessler, W. Eisner, Tarek A. Yousry, Wolf-dieter HeissAbstract:OBJECTIVE: Evaluation of the accuracy of preoperative localization of language-related cortex by magnetic resonance imaging-guided positron emission tomography. METHODS: Patients with gliomas in the left dominant hemisphere were examined preoperatively with magnetic resonance imaging-guided positron emission tomography and intraoperatively by electrical stimulation of cortex. RESULTS: A verb generation task yielded more intense and better lateralized local increases of cerebral blood flow in the positron emission tomographic examination than did a naming task. Significant correspondence of preoperative and intraoperative findings was observed for the verb generation task. Cortical sites with Aphasic Disturbance during electrical stimulation had a significantly higher cerebral blood flow increase during preoperative activation than did sites without intraoperative language impairment. Areas with cerebral blood flow increases above an optimum threshold had 73% sensitivity and 81% specificity to predict Aphasic Disturbance during intraoperative stimulation. CONCLUSION: The data suggest that with further technical improvements, imaging of language function may become a preoperative diagnostic tool for patients with tumors close to language-related brain structures.
Jeanette Wasserstein - One of the best experts on this subject based on the ideXlab platform.
-
acquired epileptiform aphasia a dimensional view of landau kleffner syndrome and the relation to regressive autistic spectrum disorders
Child Neuropsychology, 2002Co-Authors: Gerry A Stefanatos, Marcel Kinsbourne, Jeanette WassersteinAbstract:Acquired epileptiform aphasia (AEA) is characterized by deterioration in language in childhood associated with seizures or epileptiform electroencephalographic abnormalities. Despite an extensive literature, discrepancies and contradictions surround its definition and nosological boundaries. This paper reviews current conceptions of AEA and highlights variations in the Aphasic Disturbance, age of onset, epileptiform EEG abnormalities, temporal course, and long-term outcome. We suggest that AEA, rather than being a discrete entity, is comprised of multiple variants that have in common the features of language regression and epileptiform changes on EEG. Viewed this way, we argue that AEA can be conceptualized on a spectrum with other epileptiform neurocognitive disorders that may share pathophysiological features. The implications of this viewpoint are discussed, with emphasis on parallels between the AEA variants and regressive autistic spectrum disorders.
Gloria Waters - One of the best experts on this subject based on the ideXlab platform.
-
on the structure of verbal short term memory and its functional role in sentence comprehension evidence from neuropsychology
Cognitive Neuropsychology, 1991Co-Authors: Gloria Waters, David Caplan, Nancy HildebrandtAbstract:Abstract We present a case of a patient with a disorder of short-term memory. BO has a reduced span (2 to 3 items), no recency effect in free recall, and rapid forgetting in Brown-Peterson tasks, establishing her as a patient with impaired short-term verbal memory functions. She shows no effect of either phonological similarity or word length in recall of auditory or written word lists, but some recency effect under recall-from-end conditions and better performance on Brown-Peterson tasks in an unfilled than in a filled condition. This pattern of performance is interpreted as being consistent with a primary Disturbance of the articulatory rehearsal processes of S.T.M. and possibly some impairment of the phonological store (using Baddeley's 1986 terminology). Her Aphasic Disturbance—apraxia of speech—is also consistent with a Disturbance of articulatory rehearsal. BO shows a retained ability to extract phonology from print, including an ability to apply sublexical grapheme-phoneme correspondences, thus ind...