The Experts below are selected from a list of 267 Experts worldwide ranked by ideXlab platform
In-seok Lee - One of the best experts on this subject based on the ideXlab platform.
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assessment of Characteristic Distribution of pcdd fs and bfrs in sludge generated at municipal and industrial wastewater treatment plants
Chemosphere, 2012Co-Authors: In-kyu Hwang, Hee-hyung Kang, In-seok LeeAbstract:Abstract The presence of polychlorinated dibenzo- p -dioxins and furan (PCDD/Fs) and brominated flame retardants (BFRs) in sludge generated at municipal wastewater treatment plants (MWTPs) and industrial wastewater treatment plants (IWTPs) was investigated. The concentrations of these pollutants were in the following ranges: 5.38–7947 ng kg −1 dw (0.02–49.9 ng WHO-TEQ kg −1 dw) for 17 PCDD/Fs, 17.5–66 761 μg kg −1 dw for 27 polybrominated diphenyl ethers (PBDEs), 1.55–29 604 μg kg −1 dw for hexabromocyclododecanes (HBCDs) ( α -, β -, and γ -diastereomers), and 4.01–618 μg kg −1 dw for tetrabromobisphenol A (TBBPA). Generally, the levels of each compound in the sewage-sludge samples were higher than those in the industrial-sludge samples with some exceptions. The Characteristic Distribution profiles of target compounds were observed for different types of sludge and different sources of wastewater. High-chlorinated PCDD/Fs were dominant in all samples except those from the textile industry. The Distribution of the BFRs in industrial-sludge samples varied, whereas that of the BFRs in sewage-sludge samples was consistent. The proportion of penta-BDEs in sewage sludge was higher than that in industrial sludge, even though BDE-209 was the most dominant congener in all the samples. For HBCDs, the Distribution of diastereomers ( α -, β -, and γ -HBCD) was similar across sludge samples that had the same source of wastewater and treatment processes.
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Assessment of Characteristic Distribution of PCDD/Fs and BFRs in sludge generated at municipal and industrial wastewater treatment plants.
Chemosphere, 2012Co-Authors: In-kyu Hwang, Hee-hyung Kang, In-seok LeeAbstract:Abstract The presence of polychlorinated dibenzo- p -dioxins and furan (PCDD/Fs) and brominated flame retardants (BFRs) in sludge generated at municipal wastewater treatment plants (MWTPs) and industrial wastewater treatment plants (IWTPs) was investigated. The concentrations of these pollutants were in the following ranges: 5.38–7947 ng kg −1 dw (0.02–49.9 ng WHO-TEQ kg −1 dw) for 17 PCDD/Fs, 17.5–66 761 μg kg −1 dw for 27 polybrominated diphenyl ethers (PBDEs), 1.55–29 604 μg kg −1 dw for hexabromocyclododecanes (HBCDs) ( α -, β -, and γ -diastereomers), and 4.01–618 μg kg −1 dw for tetrabromobisphenol A (TBBPA). Generally, the levels of each compound in the sewage-sludge samples were higher than those in the industrial-sludge samples with some exceptions. The Characteristic Distribution profiles of target compounds were observed for different types of sludge and different sources of wastewater. High-chlorinated PCDD/Fs were dominant in all samples except those from the textile industry. The Distribution of the BFRs in industrial-sludge samples varied, whereas that of the BFRs in sewage-sludge samples was consistent. The proportion of penta-BDEs in sewage sludge was higher than that in industrial sludge, even though BDE-209 was the most dominant congener in all the samples. For HBCDs, the Distribution of diastereomers ( α -, β -, and γ -HBCD) was similar across sludge samples that had the same source of wastewater and treatment processes.
In-kyu Hwang - One of the best experts on this subject based on the ideXlab platform.
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assessment of Characteristic Distribution of pcdd fs and bfrs in sludge generated at municipal and industrial wastewater treatment plants
Chemosphere, 2012Co-Authors: In-kyu Hwang, Hee-hyung Kang, In-seok LeeAbstract:Abstract The presence of polychlorinated dibenzo- p -dioxins and furan (PCDD/Fs) and brominated flame retardants (BFRs) in sludge generated at municipal wastewater treatment plants (MWTPs) and industrial wastewater treatment plants (IWTPs) was investigated. The concentrations of these pollutants were in the following ranges: 5.38–7947 ng kg −1 dw (0.02–49.9 ng WHO-TEQ kg −1 dw) for 17 PCDD/Fs, 17.5–66 761 μg kg −1 dw for 27 polybrominated diphenyl ethers (PBDEs), 1.55–29 604 μg kg −1 dw for hexabromocyclododecanes (HBCDs) ( α -, β -, and γ -diastereomers), and 4.01–618 μg kg −1 dw for tetrabromobisphenol A (TBBPA). Generally, the levels of each compound in the sewage-sludge samples were higher than those in the industrial-sludge samples with some exceptions. The Characteristic Distribution profiles of target compounds were observed for different types of sludge and different sources of wastewater. High-chlorinated PCDD/Fs were dominant in all samples except those from the textile industry. The Distribution of the BFRs in industrial-sludge samples varied, whereas that of the BFRs in sewage-sludge samples was consistent. The proportion of penta-BDEs in sewage sludge was higher than that in industrial sludge, even though BDE-209 was the most dominant congener in all the samples. For HBCDs, the Distribution of diastereomers ( α -, β -, and γ -HBCD) was similar across sludge samples that had the same source of wastewater and treatment processes.
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Assessment of Characteristic Distribution of PCDD/Fs and BFRs in sludge generated at municipal and industrial wastewater treatment plants.
Chemosphere, 2012Co-Authors: In-kyu Hwang, Hee-hyung Kang, In-seok LeeAbstract:Abstract The presence of polychlorinated dibenzo- p -dioxins and furan (PCDD/Fs) and brominated flame retardants (BFRs) in sludge generated at municipal wastewater treatment plants (MWTPs) and industrial wastewater treatment plants (IWTPs) was investigated. The concentrations of these pollutants were in the following ranges: 5.38–7947 ng kg −1 dw (0.02–49.9 ng WHO-TEQ kg −1 dw) for 17 PCDD/Fs, 17.5–66 761 μg kg −1 dw for 27 polybrominated diphenyl ethers (PBDEs), 1.55–29 604 μg kg −1 dw for hexabromocyclododecanes (HBCDs) ( α -, β -, and γ -diastereomers), and 4.01–618 μg kg −1 dw for tetrabromobisphenol A (TBBPA). Generally, the levels of each compound in the sewage-sludge samples were higher than those in the industrial-sludge samples with some exceptions. The Characteristic Distribution profiles of target compounds were observed for different types of sludge and different sources of wastewater. High-chlorinated PCDD/Fs were dominant in all samples except those from the textile industry. The Distribution of the BFRs in industrial-sludge samples varied, whereas that of the BFRs in sewage-sludge samples was consistent. The proportion of penta-BDEs in sewage sludge was higher than that in industrial sludge, even though BDE-209 was the most dominant congener in all the samples. For HBCDs, the Distribution of diastereomers ( α -, β -, and γ -HBCD) was similar across sludge samples that had the same source of wastewater and treatment processes.
Naoki Unno - One of the best experts on this subject based on the ideXlab platform.
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Characteristic Distribution Pattern of Lysophosphatidylcholine in Fibromuscular Dysplasia-Associated Visceral Artery Aneurysms Compared with Atherosclerotic Visceral Artery Aneurysms
Journal of atherosclerosis and thrombosis, 2015Co-Authors: Hiroki Tanaka, Nobuhiro Zaima, Mitsutoshi Setou, Takeshi Sasaki, Naoto Yamamoto, Kazunori Inuzuka, Masaki Sano, Hiroyuki Konno, Tetsumei Urano, Naoki UnnoAbstract:AIM Asymptomatic visceral artery aneurysms (VAAs) have increasingly been found, with most being either atherosclerotic VAAs or fibromuscular dysplasia (FMD)-associated VAAs. However, little is known about the pathogenesis of both diseases. We aimed to identify the differences in the Distribution pattern of lipid molecules between atherosclerotic VAAs and FMD-associated VAAs. METHODS We conducted a histological study of VAAs using imaging mass spectrometry (IMS) to assess the accumulation of lipid molecules in both the aneurysmal sac and the adjacent arteries without aneurysmal changes in 17 VAA samples, which were resected during the surgery. RESULTS IMS revealed Characteristic Distributions of cholesterol ester in intima and media in the atherosclerotic VAAs, which was hardly detected in FMD-associated VAAs. However, lysophosphatidylcholine (lysoPC), a proinflammatory and proapoptotic lipid mediator, was accumulated in the medial ridge of the adventitia of FMD-associated in the aneurysmal sac, and it was also diffusely accumulated in the adjacent arteries. In contrast, lysoPC was accumulated in the area of intimal hyperplasia in atherosclerotic VAAs and the adjacent arteries. CONCLUSION The Distribution patterns of lipid molecules were different between the FMD-associated and atherosclerotic VAAs. The diffuse accumulation of lysoPCs in the visceral arteries may be a predisposition for the formation of FMD-associated VAAs.
Hee-hyung Kang - One of the best experts on this subject based on the ideXlab platform.
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assessment of Characteristic Distribution of pcdd fs and bfrs in sludge generated at municipal and industrial wastewater treatment plants
Chemosphere, 2012Co-Authors: In-kyu Hwang, Hee-hyung Kang, In-seok LeeAbstract:Abstract The presence of polychlorinated dibenzo- p -dioxins and furan (PCDD/Fs) and brominated flame retardants (BFRs) in sludge generated at municipal wastewater treatment plants (MWTPs) and industrial wastewater treatment plants (IWTPs) was investigated. The concentrations of these pollutants were in the following ranges: 5.38–7947 ng kg −1 dw (0.02–49.9 ng WHO-TEQ kg −1 dw) for 17 PCDD/Fs, 17.5–66 761 μg kg −1 dw for 27 polybrominated diphenyl ethers (PBDEs), 1.55–29 604 μg kg −1 dw for hexabromocyclododecanes (HBCDs) ( α -, β -, and γ -diastereomers), and 4.01–618 μg kg −1 dw for tetrabromobisphenol A (TBBPA). Generally, the levels of each compound in the sewage-sludge samples were higher than those in the industrial-sludge samples with some exceptions. The Characteristic Distribution profiles of target compounds were observed for different types of sludge and different sources of wastewater. High-chlorinated PCDD/Fs were dominant in all samples except those from the textile industry. The Distribution of the BFRs in industrial-sludge samples varied, whereas that of the BFRs in sewage-sludge samples was consistent. The proportion of penta-BDEs in sewage sludge was higher than that in industrial sludge, even though BDE-209 was the most dominant congener in all the samples. For HBCDs, the Distribution of diastereomers ( α -, β -, and γ -HBCD) was similar across sludge samples that had the same source of wastewater and treatment processes.
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Assessment of Characteristic Distribution of PCDD/Fs and BFRs in sludge generated at municipal and industrial wastewater treatment plants.
Chemosphere, 2012Co-Authors: In-kyu Hwang, Hee-hyung Kang, In-seok LeeAbstract:Abstract The presence of polychlorinated dibenzo- p -dioxins and furan (PCDD/Fs) and brominated flame retardants (BFRs) in sludge generated at municipal wastewater treatment plants (MWTPs) and industrial wastewater treatment plants (IWTPs) was investigated. The concentrations of these pollutants were in the following ranges: 5.38–7947 ng kg −1 dw (0.02–49.9 ng WHO-TEQ kg −1 dw) for 17 PCDD/Fs, 17.5–66 761 μg kg −1 dw for 27 polybrominated diphenyl ethers (PBDEs), 1.55–29 604 μg kg −1 dw for hexabromocyclododecanes (HBCDs) ( α -, β -, and γ -diastereomers), and 4.01–618 μg kg −1 dw for tetrabromobisphenol A (TBBPA). Generally, the levels of each compound in the sewage-sludge samples were higher than those in the industrial-sludge samples with some exceptions. The Characteristic Distribution profiles of target compounds were observed for different types of sludge and different sources of wastewater. High-chlorinated PCDD/Fs were dominant in all samples except those from the textile industry. The Distribution of the BFRs in industrial-sludge samples varied, whereas that of the BFRs in sewage-sludge samples was consistent. The proportion of penta-BDEs in sewage sludge was higher than that in industrial sludge, even though BDE-209 was the most dominant congener in all the samples. For HBCDs, the Distribution of diastereomers ( α -, β -, and γ -HBCD) was similar across sludge samples that had the same source of wastewater and treatment processes.
Nobuhiro Zaima - One of the best experts on this subject based on the ideXlab platform.
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Characteristic Distribution Pattern of Lysophosphatidylcholine in Fibromuscular Dysplasia-Associated Visceral Artery Aneurysms Compared with Atherosclerotic Visceral Artery Aneurysms
Journal of atherosclerosis and thrombosis, 2015Co-Authors: Hiroki Tanaka, Nobuhiro Zaima, Mitsutoshi Setou, Takeshi Sasaki, Naoto Yamamoto, Kazunori Inuzuka, Masaki Sano, Hiroyuki Konno, Tetsumei Urano, Naoki UnnoAbstract:AIM Asymptomatic visceral artery aneurysms (VAAs) have increasingly been found, with most being either atherosclerotic VAAs or fibromuscular dysplasia (FMD)-associated VAAs. However, little is known about the pathogenesis of both diseases. We aimed to identify the differences in the Distribution pattern of lipid molecules between atherosclerotic VAAs and FMD-associated VAAs. METHODS We conducted a histological study of VAAs using imaging mass spectrometry (IMS) to assess the accumulation of lipid molecules in both the aneurysmal sac and the adjacent arteries without aneurysmal changes in 17 VAA samples, which were resected during the surgery. RESULTS IMS revealed Characteristic Distributions of cholesterol ester in intima and media in the atherosclerotic VAAs, which was hardly detected in FMD-associated VAAs. However, lysophosphatidylcholine (lysoPC), a proinflammatory and proapoptotic lipid mediator, was accumulated in the medial ridge of the adventitia of FMD-associated in the aneurysmal sac, and it was also diffusely accumulated in the adjacent arteries. In contrast, lysoPC was accumulated in the area of intimal hyperplasia in atherosclerotic VAAs and the adjacent arteries. CONCLUSION The Distribution patterns of lipid molecules were different between the FMD-associated and atherosclerotic VAAs. The diffuse accumulation of lysoPCs in the visceral arteries may be a predisposition for the formation of FMD-associated VAAs.
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imaging mass spectrometry for lipidomics
Biochimica et Biophysica Acta, 2011Co-Authors: Naoko Gotoinoue, Takahiro Hayasaka, Nobuhiro Zaima, Mitsutoshi SetouAbstract:Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a powerful tool that enables the simultaneous detection and identification of biomolecules in analytes. MALDI-imaging mass spectrometry (MALDI-IMS) is a two-dimensional MALDI-MS technique used to visualize the spatial Distribution of biomolecules without extraction, purification, separation, or labeling of biological samples. This technique can reveal the Distribution of hundreds of ion signals in a single measurement and also helps in understanding the cellular profile of the biological system. MALDI-IMS has already revealed the Characteristic Distribution of several kinds of lipids in various tissues. The versatility of MALDI-IMS has opened a new frontier in several fields, especially in lipidomics. In this review, we describe the methodology and applications of MALDI-IMS to biological samples. This article is part of a Special Issue entitled: Lipodomics and Imaging Mass Spectrometry.